感染控制与患者安全
方法
- 对每位患者都从标准预防开始:手卫生、针对预期暴露的个人防护装备、安全使用锐器。
- 按传播途径追加预防措施:接触传播(隔离衣、手套)、飞沫传播(外科口罩)、空气传播(N95、负压病房)。
- 保持无菌物品的无菌状态:如有疑问就视为不无菌;更换,绝不擦拭。
- 预防环境中的伤害:防跌倒措施,约束仅作为最后手段,火灾时用 RACE 和 PASS。
- 核对给药的正确原则、两个身份识别信息,以及对高警示药物的额外保障;报告差错和险兆事件。
公式表、每个专题的关键方法步骤和 40 道练习题,完整解答附在最后。
When should blood cultures be taken in a patient with suspected sepsis?
在 SBAR 沟通工具中,"A"代表什么?
Which type of white blood cell is most often raised in viral infections?
A patient has a rash, and both smallpox and chickenpox are considered. Which finding suggests smallpox?
A patient’s chest tube becomes disconnected from the drainage system. What should the nurse do first?
一名护士正在监督一名新的护理助理。护士何时应最仔细地检查助理的工作?
一名 1 型糖尿病患者血糖 25 mmol/L,呼吸深快,尿中有酮体。最可能的诊断是什么?
A few hours after cardiac surgery, a patient has low blood pressure, a raised jugular venous pressure and quiet, muffled heart sounds. What should be suspected?
一名意识清醒的患者血糖为 54 mg/dL(3.0 mmol/L),已摄入 15 g 速效碳水化合物。应在何时复测血糖?
A patient taking an SGLT2 inhibitor has nausea and fast breathing. Glucose 190 mg/dL (10.5 mmol/L), pH 7.15, bicarbonate 10 mEq/L, blood ketones high. What is the most likely diagnosis?
为什么多西环素不应与牛奶或抗酸药同时服用?
A patient on simvastatin is prescribed gemfibrozil. What is the main concern?
A patient is starting doxazosin, an alpha-blocker, for hypertension. Which advice is most important?
Three days after an MI, a patient faints on the commode while straining hard to open the bowels. The heart rate was 42/min at the time. What is the most likely mechanism?
哪种电解质模式是 Addison 病的典型表现?
A patient with lung cancer is confused, dehydrated and constipated, with a corrected calcium of 3.4 mmol/L (about 13.6 mg/dL). What is usually the first treatment?
What is achalasia?
一名小肠梗阻患者的鼻胃管每天引流 2 L。哪项护理重点最重要?
一名哺乳期母亲在产后第 2 天哺乳时出现产后痛(痉挛痛)。如何解释?
Over the last hour, a labour tracing shows variable decelerations that are becoming deeper and longer, a baseline rising from 135 to 165 bpm and falling variability. How should the nurse interpret this?
How is urine output measured in an infant wearing nappies?
Which finding in a teenager with anorexia nervosa most clearly suggests the need for hospital admission?
Which feature helps distinguish normal grief from major depression?
During a ward community meeting, several patients complain that the ward is too noisy at night. What reflects a therapeutic milieu?
练习题(虚构数值,不作为临床指导)。 一次小剂量注射的计算得到 0.46054 mL。 本练习的规则是:低于 1 mL 的体积取到最接近的百分之一 mL。你记录的数值x是多少?
练习题(虚构数值,不作为临床指导)。 血糖结果为 9.1 mmol/L。按葡萄糖 1 mmol/L = 18 mg/dL,求以 mg/dL 表示的c,取到最接近的整数。
一名体重 16 kg 的儿童按 3 mg/kg 处方用药。原液浓度为 20 mg/mL。请抽取剂量:应给多少体积 V?
一袋输液在 500 mL 中含 25000 单位药物。医嘱为每小时 1200 单位。泵速 R 应设为多少 mL/h?
医嘱要求在 12 小时内输入 500 mL。6 小时后你发现袋中还剩 330 mL,而输液仍须按时完成。 必须把泵重新设定为多少 mL/h 的速率 R?
一袋中含有 4 g 药物,溶于 500 mL。医嘱为每分钟 1.5 mg。泵速 R 应设为多少 mL/h?
练习题(虚构数值,不作为临床指导)。 一袋中含肝素 25 000 单位,容量 250 mL。医嘱为 18 units/kg/h,患者体重 90 kg。输液泵速率 R 应设为多少 mL/h? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 一份含dopamine 800 mg、容量 500 mL 的输液以 7 mL/h 输注。患者体重 95 kg。患者接受的剂量 D 是多少 mcg/kg/min? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 记录显示了一名患者在一个 12 小时班次中的出入量。静脉输液在整个班次中按所示速率输注。求总入量 I,以 mL 计。 冰屑按其体积的一半计。
练习题(虚构数值,不作为临床指导)。 一袋 1000 mL 的液体用输液泵以 150 mL/h 输注。到 18:00 时已输入 400 mL。还要多少小时 t 袋子才会输完? 保留一位小数。
练习题(虚构数值,不作为临床指导)。 用 Morse 跌倒评分评估一位练习患者:过去 3 个月内的跌倒史: 是; 次要诊断: 否; 行走辅助: 扶着家具; 静脉输液或封管: 是; 步态: 受损; 精神状态: 高估或忘记自身局限。求 Morse 总分MFS。
练习题(虚构数值,不作为临床指导)。 用 Braden 量表评估一位练习患者:感觉知觉: 轻度受限; 潮湿程度: 很少潮湿; 活动: 卧床不起; 活动能力: 非常受限; 营养: 充足; 摩擦力和剪切力: 有问题。使用的分级为:19–23 无风险,15–18 轻度,13–14 中度,10–12 高,9 或以下极高。点击风险等级。
某练习血气显示代谢性酸中毒,HCO₃⁻ 14 mmol/L。用温特公式求预期PaCO₂(范围的中心),单位 mmHg。
在海平面,某练习血气取自吸入 30% 氧气时,显示 PaO₂ 54 mmHg (7.2 kPa),PaCO₂ 39 mmHg (5.2 kPa)。用 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 求A–a 梯度。
在这条规则的 II 导联心电图上测量 QT 间期和 R–R 间期,然后用 Bazett 公式 QTc = QT/√RR(均以秒计)计算经心率校正的QTc。答案以秒表示,保留三位小数。
一位摸不到脉搏的患者,监护仪上显示这种有组织的心律(无脉性电活动)。成人复苏指南为它推荐哪种治疗?点击你的答案。
答案: D · Before antibiotics are given, as long as this does not delay them
Taking cultures first gives the best chance of identifying the organism. They are collected with strict asepsis, but antibiotics must not be delayed in sepsis.
答案: D · Assessment(评估)
SBAR:Situation(现状)、Background(背景)、Assessment(你对问题的临床判断)和 Recommendation(你需要什么)。
答案: D · Lymphocytes
Lymphocytes increase in many viral infections. Neutrophils rise mainly with bacterial infections, and eosinophils with allergies and parasites.
答案: B · Lesions all at the same stage, most dense on the face and limbs
In smallpox, lesions develop at the same stage in any one area and are densest on the face and extremities. In chickenpox, crops appear at different stages and are densest on the trunk.
答案: D · Place the end of the tube in a bottle of sterile water
Putting the tube end in sterile water creates a temporary water seal until a new drainage system is connected. Long clamping can cause a tension pneumothorax, and the nurse does not remove the tube.
答案: C · 当助理对该任务不熟悉或患者不太稳定时
当被委派者经验较少、患者病情较难预测或任务风险较高时,需要更多的监督。被动的或班次结束时才检查,可能在还能纠正的时候错过问题。
答案: D · 糖尿病酮症酸中毒
高血糖、酮体和酸中毒伴 Kussmaul 呼吸提示 DKA。治疗包括补液、胰岛素和密切监测血钾。
答案: C · Cardiac tamponade
Hypotension, raised JVP and muffled heart sounds (Beck's triad) suggest cardiac tamponade. Blood in the pericardial space compresses the heart and needs urgent drainage.
答案: A · 约 15 分钟后
15 法则是指摄入 15 g 速效碳水化合物,15 分钟后复测,如果血糖仍低于 70 mg/dL(3.9 mmol/L)则重复。然后再吃点心或正餐有助于预防复发。核对依据: Low blood sugar - self-care · MedlinePlus (NIH) (2026)
答案: C · Euglycemic diabetic ketoacidosis
SGLT2 inhibitors can cause DKA with only mildly raised glucose because glucose is lost in the urine. Ketones and acidosis must be checked in any unwell patient on these drugs, even with a near-normal glucose.核对依据: Ketones blood test · MedlinePlus (NIH) (2025)
答案: B · 钙和其他金属离子会与之结合,减少吸收
四环素类在肠道中与钙、镁、铝和铁形成络合物,从而减少吸收。服药时间应与这些产品错开。
答案: D · A much higher risk of myopathy and rhabdomyolysis
Gemfibrozil reduces statin clearance and adds its own muscle toxicity. The combination greatly increases the risk of rhabdomyolysis and is generally avoided.
答案: A · Take the first dose at bedtime, as dizziness and fainting can occur
Alpha-blockers can cause marked first-dose postural hypotension. Taking the first dose at bedtime and rising slowly reduces the risk of falls. They are also used for symptoms of an enlarged prostate.
答案: C · A vagal response to straining
Straining (the Valsalva manoeuvre) can cause a vagal bradycardia and a fall in cardiac output, leading to syncope. After an MI, stool softeners, adequate fluids and avoiding straining are advised. The event is still reported and the patient assessed for arrhythmia or ischaemia.
答案: C · 低钠高钾
醛固酮缺乏导致失钠、钾潴留,引起低钠血症和高钾血症。皮质醇缺乏还会加上低血糖和低血压。
答案: C · IV fluids to rehydrate the patient
Hypercalcaemia causes polyuria and dehydration, which worsen the high calcium. IV fluids are the first step, followed by a bisphosphonate to reduce bone resorption. Calcium is rechecked regularly.
答案: A · Failure of the lower oesophageal sphincter to relax on swallowing
In achalasia, peristalsis is lost and the lower oesophageal sphincter does not relax, causing dysphagia to both solids and liquids, regurgitation and weight loss. Treatments include dilatation and surgical myotomy.
答案: D · 准确的液体平衡,配合静脉补充和电解质检查
鼻胃管大量丢失可引起脱水、低钾血症和低氯性代谢性碱中毒。应测量并记录引流量,按医嘱静脉补充(常用含钾晶体液),并至少每天检查尿素、肌酐和电解质。口服液体会增加丢失和呕吐风险。
答案: B · 哺乳时释放的缩宫素使子宫收缩
吸吮释放缩宫素,引起乳汁排出和子宫收缩。产后痛是正常的,经产妇常常更明显。排空膀胱和使用简单的镇痛药有帮助。
答案: A · Evolving fetal hypoxia; escalate for urgent obstetric review
Deepening decelerations with a rising baseline and falling variability show that the fetus is losing its ability to compensate. Intrauterine resuscitation (position change, stopping any oxytocin, treating hypotension) starts and the obstetrician is called urgently, because expedited birth may be needed.
答案: D · Weigh the wet nappy and subtract the dry weight; 1 g is about 1 mL
Weighing nappies before and after use gives an accurate measure of urine output, as 1 g of urine is about 1 mL. This is important in sick infants to calculate output in mL/kg/hour.
答案: B · Fainting episodes with a very slow heart rate and low potassium
Admission is considered for medical instability, such as marked bradycardia, low or postural blood pressure, fainting, hypothermia, electrolyte problems or refusal to eat. Medical risk is judged on the whole picture, not on weight alone.
答案: D · In grief, painful feelings come in waves and self-esteem is usually kept
In grief, sadness tends to come in waves linked to reminders of the loss, and positive memories and humour are possible. Pervasive worthlessness, self-loathing and hopelessness suggest depression.
答案: A · Discuss the problem openly and involve patients in finding a solution
In a therapeutic milieu, the ward environment itself is used for treatment. Shared decision-making in community meetings builds responsibility, social skills and trust.
答案: x = 0.46 mL
取整:看舍入位后面的那个数字:5 或更大则进位,4 或更小则保持原数字不变。只对最终答案取整,绝不对中间步骤取整。典型的考试规则:1 mL 或以上的体积取到十分位,低于 1 mL 的体积取到百分位,滴速取整到整滴,体重取到一位小数;务必遵循题目所规定的规则。
答案: c = 164 mg/dL
量纲分析:先写出已知量,再乘以写成分数形式的换算系数(例如 60 min/1 h 或 1 mg/1000 mcg),使每个不需要的单位在分子和分母各出现一次并相互约去。只剩下所求单位时再计算。使用题目给出的等量关系,只对最终答案取整。
答案: V = 2.4 mL
抽取剂量:体积 = (处方剂量/药物浓度) × 药物体积。先换算成相同的单位,再检查该体积是否适合注射器,并落在它的某一个刻度上。
在这支 10 mL 的注射器上,每条小刻度线代表 0.2 mL。
答案: R = 24 mL/h
剂量计算:给药量等于医嘱剂量除以现有药物的规格,再乘以该规格对应的量:给药量 = (医嘱剂量/储备规格) × 储备体积。始终统一单位(先把 g 换成 mg,mg 换成 mcg),并检查答案是否合理。
答案: R = 55 mL/h
Infusion rates: a pump is set in mL/h = volume/time in hours. A gravity drip is counted in drops per minute: gtt/min = volume (mL) × drop factor (gtt/mL)/time (min). The drop factor is printed on the tubing package: macrodrip sets deliver 10, 15 or 20 gtt/mL (blood sets often 10 gtt/mL in the US, 15 in the UK) and microdrip sets 60 gtt/mL. Always use the drop factor the question or package gives.
这超过了 25% 的增幅:大多数医院要求你联系开医嘱者,而不是加快补输,并评估患者是否存在液体过多。
答案: R = 11.25 mL/h
Dose-based infusions: concentration = amount of drug in the bag/bag volume. Pump rate (mL/h) = dose per hour/concentration, and dose per hour = mL/h × concentration. Convert per-minute doses to per-hour (× 60) and keep the mass units the same (1 g = 1000 mg, 1 mg = 1000 mcg).
答案: R = 16.2 mL/h
肝素和胰岛素输注:浓度 = 袋中单位数/袋容量 (units/mL)。泵速 (mL/h) = 每小时单位数/浓度,每小时单位数 = mL/h × 浓度。按体重给药时,先求 units/h = units/kg/h × 体重。推注体积 = 所需单位数/药瓶规格。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: D = 2 mcg/kg/min
滴定输注:先求以 mcg/mL 计的浓度(mg × 1000/mL)。按体重给药时,mcg/min = mcg/kg/min × 体重。然后 mL/h = mcg/min × 60/浓度。反推时,mcg/kg/min = mL/h × 浓度/(60 × 体重)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: I = 1430 mL
出入量:入量计入所有进入体内的液体(口服液体、静脉输液、静脉用药及冲管液、管饲);冰屑按其体积的一半计。出量计入尿液、引流液、呕吐物和其他丢失。平衡 = 总入量 − 总出量;平衡为负表示净丢失。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
答案: t = 4 h
输液时间:时间 (h) = 待输体积 (mL)/速率 (mL/h);使用袋中剩余的体积,而不是袋的容量。已输入体积 = 速率 × 时间。把小数小时换算为小时和分钟时,用小数部分 × 60(0.5 h = 30 min,而不是 50 min)。 这些数字仅供练习;在临床工作中务必遵循当地规程,高危剂量须经双人核对。
约为 4 h 00 min,所以袋子大约在 22:00 输完。
答案: MFS = 110
Morse 跌倒评分:六个条目。跌倒史:否 0 分,是 25 分。次要诊断:否 0 分,是 15 分。行走辅助:无、卧床休息或护士协助 0 分;拐杖、手杖或助行器 15 分;扶着家具 30 分。静脉输液或封管:否 0 分,是 20 分。步态:正常、卧床休息或轮椅 0 分;虚弱 10 分;受损 20 分。精神状态:了解自身局限 0 分;高估或忘记自身局限 15 分。总分为 0 至 125。各医院的风险分界值不同;常用的一套是 0–24 低风险,25–44 中度风险,45 及以上为高风险。
答案: 中度风险
Braden 量表:评估压力性损伤风险的六个分项。感觉知觉、潮湿程度、活动、活动能力和营养各评 1 至 4 分,从最差水平(1)到无问题(4);摩擦力和剪切力评 1 至 3 分。总分为 6 至 23,总分越低风险越高。常用分级:19–23 无风险,15–18 轻度风险,13–14 中度风险,10–12 高风险,9 分及以下为极高风险。
答案: PaCO₂ = 29 mmHg
预期代偿:代谢性酸中毒时,温特公式预测 PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg;实测值高于该范围提示合并呼吸性酸中毒,低于该范围提示合并呼吸性碱中毒。阴离子间隙 AG = Na⁺ − (Cl⁻ + HCO₃⁻),正常约为 8–12 mmol/L,用于区分高阴离子间隙与正常阴离子间隙代谢性酸中毒;低白蛋白会掩盖升高的间隙(白蛋白低于 4.0 的部分,每 g/dL 加 2.5)。Δ 比值 (AG − 12)/(24 − HCO₃⁻) 约在 0.8 到 2 之间符合单纯高间隙酸中毒(有些教材用 1 代替 0.8),低于此范围提示合并正常间隙酸中毒,高于 2 提示合并代谢性碱中毒。
答案: A–a 梯度 = 111.2 mmHg
衍生数值:计算所得的血清渗透压为 2·Na⁺ + 葡萄糖 + 尿素,各值均以 mmol/L 计(葡萄糖和 BUN 以 mg/dL 计时为 2·Na⁺ + 葡萄糖/18 + BUN/2.8);正常约为 275–295 mOsm/kg。P/F 比值是 PaO₂ 除以以小数表示的 FiO₂。海平面的肺泡氧分压为 PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg,A–a 梯度为 PAO₂ − PaO₂。
答案: QTc = 0.44 s
QT 与 QTc:QT 间期从 QRS 波群起点到 T 波终点。它随心率加快而缩短,因此要用以秒为单位的 R–R 间期按心率校正:Bazett QTc = QT/√RR,Fridericia QTc = QT/∛RR。多数教科书使用 Bazett 公式;它在心率快时校正过度,此时宜用 Fridericia。各参考标准的界限不同:QTc 男性高于约 0.45 s、女性高于约 0.46 s 通常称为延长,高于 0.50 s 称为明显延长。
在通常上限之内(男性约 0.45 s,女性约 0.46 s)。(440 ms)
答案: 心肺复苏(不可电击心律)
无脉性电活动(PEA):PEA 无法从心电图条带上看出。监护仪显示有组织的电活动(VF、VT 或心搏停止以外的心律),但患者摸不到脉搏,因此要通过检查患者来识别。在成人复苏指南中,PEA 和心搏停止是不可电击的心脏骤停心律:进行高质量心肺复苏,尽快使用肾上腺素,并寻找可逆原因(5H 和 5T,如低血容量、缺氧、张力性气胸和心脏压塞)。VF 和无脉性 VT 是可电击心律。
PEA 在床旁识别,绝不能仅凭心电图条带。这是考试练习,不是临床指南。
本内容为独立练习材料。ExamProblems 与该考试的主办机构没有隶属关系,也未获其认可,考试名称仅用于描述内容。 NCLEX®, NCLEX-RN® and NCLEX-PN® 是 the National Council of State Boards of Nursing, Inc. (NCSBN) 的商标,该机构与 ExamProblems 无关,不为其背书,也不保证其准确性。
ExamProblems · examproblems.com/courses/nclex-rn-practice-questions