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الاسم: ____________________ التاريخ: ____________
1.سهلة
What is the normal fasting blood glucose range in a healthy adult?
A3,9–5,5 mmol/L (about 70–100 mg/dL)
B11,1–15,0 mmol/L (about 200–270 mg/dL)
C7,0–10,0 mmol/L (about 126–180 mg/dL)
D1,5–3,0 mmol/L (about 27–54 mg/dL)
2.سهلة
ما التحمّل الدوائي؟
Aتفاعل تحسسي تجاه دواء
Bاستجابة أقوى في كل مرة يؤخذ فيها الدواء
Cانخفاض الاستجابة بعد الاستخدام المتكرر، فتلزم جرعة أعلى
Dالقدرة على تناول دواء دون ظهور أي آثار جانبية على الإطلاق
3.سهلة
Why is folinic acid (leucovorin) given after high-dose methotrexate?
ATo protect normal cells from methotrexate toxicity
BTo prevent nausea and vomiting after the methotrexate
CTo make methotrexate act faster on the tumour
DTo treat an allergic reaction to methotrexate
4.متوسطة
A patient receiving chemotherapy has a very low neutrophil count and is going home. Which teaching is most important?
AEat plenty of raw shellfish to boost protein
BReport a temperature of 38 °C (100,4 °F) or higher straight away
CExercise in crowded gyms to build strength
DTake paracetamol regularly so that fevers do not show
5.متوسطة
How does sucralfate help a peptic ulcer heal?
AIt blocks histamine H2 receptors in the stomach
BIt neutralises acid by releasing bicarbonate
CIt forms a protective coating over the ulcer base
DIt kills Helicobacter pylori directly
6.متوسطة
A nurse realises that a patient has been given the wrong dose of a medicine. What is the first action?
AWait to see whether the patient notices
BCorrect the chart so it shows the right dose
CAssess the patient for effects of the error
DComplete the incident report before anything else
7.صعبة
A patient on weekly methotrexate is prescribed trimethoprim for a urinary infection. What is the main risk?
ALoss of antibiotic effect because methotrexate binds trimethoprim
BSevere hypertension from the combination
CBone marrow suppression, because both drugs inhibit folate metabolism
DHypoglycaemia from reduced liver glucose output
8.صعبة
A patient taking dabigatran has a life-threatening bleed. Which specific reversal agent is used?
AVitamin K
BIdarucizumab
CProtamine sulfate
DAndexanet alfa
مفتاح الإجابات
1. A · 3,9–5,5 mmol/L (about 70–100 mg/dL)
2. C · انخفاض الاستجابة بعد الاستخدام المتكرر، فتلزم جرعة أعلى
3. A · To protect normal cells from methotrexate toxicity
4. B · Report a temperature of 38 °C (100,4 °F) or higher straight away
5. C · It forms a protective coating over the ulcer base
6. C · Assess the patient for effects of the error
7. C · Bone marrow suppression, because both drugs inhibit folate metabolism
8. B · Idarucizumab
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