ورقة عمل علم الأدوية مع الإجابات

Why is methadone used to treat opioid use disorder?

1. AIt causes vomiting if other opioids are used
2. BIt cures the liver damage caused by opioids
3. CIt is a pure opioid antagonist that blocks all opioid effects
4. DIt is a long-acting opioid that prevents withdrawal and craving

How do second-generation antihistamines such as cetirizine and loratadine differ from older ones?

1. AThey block H2 receptors in the stomach
2. BThey work only on the skin
3. CThey cause much less drowsiness
4. DThey are given only by injection

After chemotherapy, what is the "nadir"?

1. AThe day the drug is given
2. BThe point when the tumour is at its smallest after treatment
3. CThe point when blood cell counts are at their lowest
4. DThe time when nausea is worst

كيف تخفض مثبطات SGLT2 مثل الإمباغليفلوزين سكر الدم؟

1. Aتبطئ إفراغ المعدة
2. Bتزيد فقد الغلوكوز في البول
3. Cتنبه إفراز الإنسولين من خلايا بيتا
4. Dتجعل الكبد يخزّن مزيدًا من الغليكوجين

A patient with difficulty swallowing is prescribed several tablets. Which one should not be crushed?

1. AA plain aspirin dispersible tablet
2. BA modified-release (extended-release) tablet
3. CA tablet that the pharmacist says may be crushed
4. DA plain paracetamol tablet

دواء يثبط إنزيم الكبد CYP3A4. ماذا قد يحدث لدواء ثانٍ يُستقلب أساسًا بواسطة CYP3A4؟

1. Aيرتفع مستواه في البلازما فيزداد خطر الآثار الجانبية
2. Bينخفض مستواه في البلازما فقد يتوقف عن العمل بالجرعة المعتادة
3. Cتطرحه الكليتان أسرع
4. Dلا شيء، لأن الإنزيمات لا تؤثر في الأدوية الأخرى

Why is adenosine used with caution in patients with asthma?

1. AIt causes severe hypertension in asthma
2. BIt is broken down too slowly in asthma
3. CIt can cause bronchospasm
4. DIt reduces the effect of inhaled steroids

A man on long-term testosterone therapy has a rising haematocrit. Why is this important?

1. ATestosterone raises red cell production, increasing clot risk
2. BIt means the testosterone dose is too low
3. CA high haematocrit shows that the testosterone is not being absorbed
4. DIt is a sign of liver failure caused by testosterone