ورقة عمل علم الأدوية مع الإجابات

ماذا يعني «عمر النصف» للدواء؟

1. Aالزمن اللازم لامتصاص نصف الجرعة من الأمعاء
2. Bالزمن اللازم لانخفاض تركيز الدواء في البلازما إلى النصف
3. Cالزمن حتى يبدأ الدواء بالعمل
4. Dنصف المدة التي يبقى فيها الدواء في الجسم

Filgrastim, a granulocyte colony-stimulating factor (G-CSF), is given to:

1. AIncrease the production of platelets
2. BIncrease the production of neutrophils
3. CLower the white cell count in leukaemia
4. DStop bleeding from wounds

Alendronate, used for osteoporosis, belongs to which class?

1. AThyroid hormones
2. BBisphosphonates
3. CCorticosteroids
4. DCalcium channel blockers

A patient is starting doxazosin, an alpha-1 blocker. What should the nurse advise about the first dose?

1. AExpect a short rise in blood pressure after the dose
2. BTake it in the morning with a cup of strong coffee to stay alert
3. CTake it at bedtime, because it can cause dizziness and fainting
4. DTake it only if the urine is darker than usual

أي جزء من الدواء في البلازما يمكنه الوصول إلى المستقبل وإحداث التأثير؟

1. Aالجزء المرتبط بالألبومين
2. Bالجزء المخزّن في خلايا الدم الحمراء
3. Cالجزء غير المرتبط (الحر)
4. Dالجزء المرتبط بالغلوبولينات

Why should loperamide usually be avoided in bloody diarrhoea with fever?

1. ALoperamide makes the bleeding worse by blocking platelets
2. BLoperamide is an antibiotic that causes resistance
3. CSlowing the gut may keep bacteria and toxins in the bowel longer
4. DLoperamide causes severe hypertension when there is an infection

A patient taking long-term morphine for cancer pain becomes very sedated with slow breathing. Why is naloxone given in small, diluted doses?

1. ATo restore breathing without causing severe withdrawal and pain
2. BBecause naloxone is much more potent and toxic in patients with cancer
3. CBecause naloxone is toxic to the liver in large doses
4. DTo make the effect of naloxone last longer than morphine

In myxoedema coma, why is hydrocortisone often given before or with thyroid hormone?

1. AThyroid hormone can trigger adrenal crisis if cortisol is also low
2. BHydrocortisone makes thyroid hormone work faster
3. CHydrocortisone prevents the hypoglycaemia caused by levothyroxine
4. DThyroid hormone is inactive unless hydrocortisone is given