ورقة عمل علم الأدوية مع الإجابات

Which of these drugs has a narrow therapeutic index?

1. ALithium
2. BOmeprazole
3. CAmoxicillin
4. DLoratadine

Which drug is first-line for symptomatic bradycardia in adults?

1. ADigoxin
2. BAtropine
3. CMetoprolol
4. DAdenosine

How does tamsulosin improve urine flow in benign prostatic hyperplasia?

1. AIt contracts the bladder muscle
2. BIt increases urine production in the kidney
3. CIt blocks alpha-1 receptors and relaxes prostate smooth muscle
4. DIt shrinks the prostate gland over months by blocking testosterone

Which blood test is used to monitor warfarin therapy?

1. AActivated partial thromboplastin time (aPTT)
2. BSerum albumin
3. CPlatelet count
4. DINR (prothrombin time)

كيف يُحدث الهيبارين تأثيره المضاد للتخثر؟

1. Aيعزز مضاد الثرومبين الذي يعطّل الثرومبين والعامل Xa
2. Bيثبط COX-1 في الصفائح تثبيطًا غير عكوس
3. Cيفكك الفيبرين في الجلطات الموجودة
4. Dيحجب تخليق عوامل التخثر المعتمد على فيتامين K في الكبد

أي علامة نموذجية للتسمم بالأفيونات؟

1. Aارتفاع حرارة الجسم
2. Bحدقتان متوسعتان بشدة
3. Cتنفس سريع وعميق
4. Dحدقتان دبوسيتان

Why is gentamicin often given once daily instead of in several small doses?

1. AIt is absorbed slowly from the muscle over 24 hours
2. BIts killing depends only on the time the level stays above the MIC
3. CIts killing depends on high peak levels, with a post-antibiotic effect
4. DIt has a very long half-life of several days

A patient with an epidural infusion of local anaesthetic becomes hypotensive. What is the most likely mechanism?

1. AThe drug increases urine output and causes dehydration
2. BBlockade of sympathetic nerves causes vasodilation
3. CThe epidural catheter has caused heavy bleeding
4. DThe local anaesthetic causes a severe allergic reaction