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الاسم: ____________________ التاريخ: ____________
1.سهلة
Varenicline helps people stop smoking because it:
ABlocks dopamine receptors in the brain completely
BIs a form of nicotine absorbed slowly through the skin
CMakes cigarettes taste bitter
DIs a nicotinic partial agonist that reduces craving and reward
2.سهلة
ما المقصود بالناهض (Agonist)؟
Aدواء يدمّر المستقبل
Bدواء يرتبط بالمستقبل ويحجبه
Cدواء يسرّع إطراحه الذاتي
Dدواء يرتبط بالمستقبل وينشّطه
3.سهلة
ماذا تصف «نجاعة» الدواء (efficacy)؟
Aالتأثير الأقصى الذي يمكن أن يُحدثه الدواء
Bنسبة الجرعة المرتبطة ببروتينات البلازما
Cالجرعة اللازمة لإحداث نصف التأثير
Dسرعة امتصاص الدواء
4.متوسطة
A patient is starting lamotrigine. Which adverse effect should the patient report at once?
AMild headache on the first day
BAny new skin rash
CA brief change in taste
DSlight tiredness in the afternoon
5.متوسطة
Which assessment is most important before giving a dose of IV morphine?
ABlood glucose and temperature, checked before each dose
BRespiratory rate and level of sedation
CBowel sounds and urine colour
DPupil size and hearing
6.متوسطة
A child is starting methylphenidate for ADHD. Which advice is appropriate?
AGive the drug only at weekends
BGive doses early in the day and monitor appetite and growth
CExpect weight gain as the main side effect
DGive the last dose at bedtime to help the child sleep
7.صعبة
A nurse calculates a child's dose and finds it is ten times higher than the usual range in the drug reference. What should the nurse do?
AGive one tenth of the dose without telling anyone
BGive half the dose as a compromise
CGive the dose, because the prescriber is responsible for the order
DWithhold it, recheck the calculation and clarify with the prescriber
8.صعبة
Lithium taken in the first trimester of pregnancy has been linked to which type of birth defect?
ANeural tube defects such as spina bifida
BLimb defects similar to thalidomide
CCleft lip and palate only
DHeart malformations, such as Ebstein's anomaly
مفتاح الإجابات
1. D · Is a nicotinic partial agonist that reduces craving and reward
2. D · دواء يرتبط بالمستقبل وينشّطه
3. A · التأثير الأقصى الذي يمكن أن يُحدثه الدواء
4. B · Any new skin rash
5. B · Respiratory rate and level of sedation
6. B · Give doses early in the day and monitor appetite and growth
7. D · Withhold it, recheck the calculation and clarify with the prescriber
8. D · Heart malformations, such as Ebstein's anomaly
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