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1.سهلة
Disulfiram is used in alcohol use disorder because it:
ACauses an unpleasant reaction if alcohol is drunk
BCures liver damage caused by alcohol
CRemoves alcohol from the blood faster
DReplaces alcohol at its receptors in the brain
2.سهلة
Celecoxib selectively inhibits which enzyme?
ACyclo-oxygenase-1 (COX-1)
BPhospholipase A2
CLipoxygenase
DCyclo-oxygenase-2 (COX-2)
3.سهلة
Which signs are typical of hypoglycaemia?
AFruity breath with deep, rapid breathing
BThirst, frequent urination and warm, dry, flushed skin
CSweating, shakiness, a fast heart rate and confusion
DA slow pulse, constipation and weight gain
4.متوسطة
لماذا لا ينبغي أخذ الدوكسيسيكلين في الوقت نفسه مع الحليب أو مضادات الحموضة؟
Aلأن الكالسيوم وأيونات معدنية أخرى ترتبط به فتقلل امتصاصه
Bلأن الحليب يسرّع تفككه في الكبد بتحريض الإنزيمات
Cلأن مضادات الحموضة تحوّله إلى مركّب سام
Dلأن الجمع بينهما يسبب إمساكًا شديدًا
5.متوسطة
Benzathine benzylpenicillin (penicillin G benzathine) is ordered. Which route is correct?
ADeep intramuscular only
BSubcutaneous in the abdomen
CIntravenous infusion over 30 minutes
DIntravenous push
6.متوسطة
A transplant patient takes tacrolimus. Which monitoring is most important?
ASerum amylase
BBlood drug levels and kidney function
CPeak expiratory flow
DThyroid function and bone density
7.صعبة
A patient taking azathioprine is prescribed allopurinol for gout. What is the main danger?
AGout becomes worse because allopurinol is inactivated by azathioprine
BSevere bone marrow suppression, because azathioprine breakdown is reduced
CSevere hypertension from the combination
DLiver enzyme induction, making azathioprine ineffective
8.صعبة
A patient on lisinopril for hypertension starts taking ibuprofen every day for knee pain. What is the main concern?
AA large fall in blood pressure, with fainting and falls on standing up
BWeaker blood pressure control, kidney injury and high potassium
CA higher risk of a dry cough than with lisinopril alone
DFaster liver metabolism of lisinopril, so it stops working
مفتاح الإجابات
1. A · Causes an unpleasant reaction if alcohol is drunk
2. D · Cyclo-oxygenase-2 (COX-2)
3. C · Sweating, shakiness, a fast heart rate and confusion
4. A · لأن الكالسيوم وأيونات معدنية أخرى ترتبط به فتقلل امتصاصه
5. A · Deep intramuscular only
6. B · Blood drug levels and kidney function
7. B · Severe bone marrow suppression, because azathioprine breakdown is reduced
8. B · Weaker blood pressure control, kidney injury and high potassium
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