1Practice problems
1.Human anatomyMedium
The circle of Willis at the base of the brain connects which two arterial supplies?
- AExternal carotid and subclavian arterial systems
- BJugular and vertebral systems
- CLeft and right external carotid arteries
- DInternal carotid and vertebrobasilar systems
2.Human anatomyHard
A patient with a large aneurysm of the aortic arch develops hoarseness. Which nerve is most likely compressed?
- ARight recurrent laryngeal nerve
- BExternal laryngeal nerve
- CLeft phrenic nerve
- DLeft recurrent laryngeal nerve
3.Human physiologyMedium
Where is the heart's natural pacemaker?
- APurkinje fibres
- BSinoatrial node
- CAtrioventricular node
- DBundle of His
4.Human physiologyHard
In pernicious anaemia, autoimmune destruction of gastric parietal cells leads to anaemia because:
- AAcid is lost, so iron is never absorbed in any form
- BIntrinsic factor is lost, so vitamin B12 is not absorbed
- CPepsin is lost, so haemoglobin cannot be made
- DGastrin is lost, so the bone marrow is no longer stimulated
2Solutions
1.Human anatomy
Answer: D · Internal carotid and vertebrobasilar systems
Why this is the answer
The circle of Willis links the internal carotid arteries with the basilar artery (formed by the vertebral arteries), allowing some collateral flow.
D · Internal carotid and vertebrobasilar systems
2.Human anatomy
Answer: D · Left recurrent laryngeal nerve
Why this is the answer
The left recurrent laryngeal nerve loops under the aortic arch beside the ligamentum arteriosum. It supplies most laryngeal muscles, so compression causes hoarseness.
D · Left recurrent laryngeal nerve
3.Human physiology
Answer: B · Sinoatrial node
Why this is the answer
The SA node depolarises spontaneously at the fastest rate and sets the heart rhythm. The AV node delays the impulse before it spreads to the ventricles.
4.Human physiology
Answer: B · Intrinsic factor is lost, so vitamin B12 is not absorbed
Why this is the answer
Parietal cells secrete intrinsic factor, needed for B12 absorption in the terminal ileum. B12 deficiency impairs DNA synthesis and causes megaloblastic anaemia.
B · Intrinsic factor is lost, so vitamin B12 is not absorbed