Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1.5 kcal/mL25 kcal/kg/day? mL/h71 kg24 h/day

Practice exercise (made-up values, not clinical guidance). A 71 kg adult (BMI below 30) needs 25 kcal/kg/day. The tube feed provides 1.5 kcal/mL and runs by pump for 24 hours a day. At what rate R do you set the pump, in mL/h? Round to the nearest whole number.

71 kg25 kcal/kg/day1.5 kcal/mL24 h
R = mL/h
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 17.5%1500 mLamino acids 4.25%1500 mLlipid 10%500 mL · 1.1 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1500 mL of parenteral nutrition with final concentrations of 17.5% dextrose and 4.25% amino acids, plus 500 mL of 10% lipid emulsion (1.1 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1500 mLdextrose 17.5%amino acids 4.25%lipid 500 mL · 1.1 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftjuice150 mLtea150 mLice chips200 mLIV infusion60 mL/h × 8 hIV antibiotic2 × 100 mLurine350 mLurine475 mLwound drain60 mLvomit150 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The patient weighs 103 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

103 kg8 hurine: 350 mLurine: 475 mLwound drain: 60 mLvomit: 150 mL
U = mL/kg/h
4.IV fluids & fluid balanceHard
500 mL150 mL infused100 mL/h21:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 500 mL bag runs by pump at 100 mL/h. At 21:00, 150 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

500 mL150 mL infused100 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: R = 49 mL/h

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Energy needed

E = 25·71 = 1775 kcal/day

Daily volume

V = 1775/1.5 = 1183 mL/day

Pump rate

R = 1183/24 = 49.31 ≈ 49 mL/h

Answer

R = 49 mL/h
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 141

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 17.5·1500/100 = 262.5 g
amino acids: 4.25·1500/100 = 63.75 g

Kilocalories per component

dextrose: 262.5·3.4 = 892.5 kcal
amino acids: 63.75·4 = 255 kcal
lipid: 500·1.1 = 550 kcal

Non-protein kcal and nitrogen

NPC = 892.5 + 550 = 1443 kcal
N = 63.75/6.25 = 10.2 g

Ratio

NPC : N = 1443/10.2 = 141.4 ≈ 141 : 1

Answer

NPC : N = 141

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: U = 1 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

350 + 475 = 825 mL

Per kilogram per hour

U = 825/(103·8) = 1.001 ≈ 1 mL/kg/h

Answer

U = 1 mL/kg/h
4.IV fluids & fluid balance

Answer: t = 3.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

500 − 150 = 350 mL

Time

t = 350/100 = 3.5 h

Answer

t = 3.5 h

That is about 3 h 30 min, so the bag runs out at about 00:30.

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