Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
1.2 kcal/mL81% free water75 mL/hevery 6 h61 kg · 30 mL/kg/day18 h/dayV = ? mL

Practice exercise (made-up values, not clinical guidance). A 61 kg patient has a fluid goal of 30 mL/kg/day and receives all fluid through a feeding tube. The formula is 81% free water and runs at 75 mL/h for 18 hours a day. The rest of the fluid is given as water flushes every 6 hours. What volume V is each flush? Round to the nearest whole number.

61 kg30 mL/kg/day81%75 mL/h · 18 hevery 6 h
V = mL
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 10%1200 mLamino acids 3.5%1200 mLlipid 20%100 mL · 2 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1200 mL of parenteral nutrition with final concentrations of 10% dextrose and 3.5% amino acids, plus 100 mL of 20% lipid emulsion (2 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1200 mLdextrose 10%amino acids 3.5%lipid 100 mL · 2 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput12-hour shifttea200 mLwater120 mLjuice200 mLice chips200 mLIV infusion100 mL/h × 12 hIV antibiotic1 × 50 mLurine425 mLurine225 mLvomit200 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 12-hour shift. The patient weighs 88 kg. Find the average urine output U in mL/kg/h. Round to two decimal places.

88 kg12 hurine: 425 mLurine: 225 mLvomit: 200 mL
U = mL/kg/h
4.IV fluids & fluid balanceHard
1000 mL→ 200 mL/hstart 08:00ttotal​ = ? h75 mL/h × 4 h

Practice exercise (made-up values, not clinical guidance). A 1000 mL infusion starts at 08:00 at 75 mL/h. After 4 hours the rate is changed to 200 mL/h and is not changed again. How many hours t after the start will the bag be empty? Round to one decimal place.

1000 mL75 mL/h · 4 h200 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: V = 184 mL

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Fluid goal

30·61 = 1830 mL/day

Free water from the formula

75·18 = 1350 mL
1350·0.81 = 1094 mL

Water still needed

1830 − 1094 = 736.5 mL/day

Volume per flush

24/6 = 4 flushes
V = 736.5/4 = 184.1 ≈ 184 mL

Answer

V = 184 mL
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 90

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 10·1200/100 = 120 g
amino acids: 3.5·1200/100 = 42 g

Kilocalories per component

dextrose: 120·3.4 = 408 kcal
amino acids: 42·4 = 168 kcal
lipid: 100·2 = 200 kcal

Non-protein kcal and nitrogen

NPC = 408 + 200 = 608 kcal
N = 42/6.25 = 6.72 g

Ratio

NPC : N = 608/6.72 = 90.48 ≈ 90 : 1

Answer

NPC : N = 90

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: U = 0.62 mL/kg/h

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Total urine

425 + 225 = 650 mL

Per kilogram per hour

U = 650/(88·12) = 0.6155 ≈ 0.62 mL/kg/h

Answer

U = 0.62 mL/kg/h
4.IV fluids & fluid balance

Answer: t = 7.5 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

First part

75·4 = 300 mL
1000 − 300 = 700 mL left

Second part

700/200 = 3.5 h

Total time

t = 4 + 3.5 = 7.5 h

Answer

t = 7.5 h

That is about 7 h 30 min, so the bag runs out at about 15:30.

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