Clinical Nutrition: cram pack

Formula sheets, the key method steps for every topic and 4 practice problems, with full solutions at the back.

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1Formulas and methods

Enteral & parenteral nutrition calculations

Daily volume
mL = kcal / (kcal/mL)
Continuous feed
mL/h = daily volume / hours of feeding
Bolus feed
mL per feed = daily volume / number of feeds
Energy and protein delivered
kcal = mL × kcal/mL; g = L × g/L
Free water
mL = formula volume × water fraction
Ideal body weight (Devine)
men 50 + 2.3 × (in − 60); women 45.5 + 2.3 × (in − 60); 1 in = 2.54 cm
Body mass index
BMI = kg/m²
Parenteral nutrition
dextrose 3.4 kcal/g, amino acids 4 kcal/g, lipid 20% 2.0 kcal/mL, 10% 1.1 kcal/mL
Nitrogen
g N = g protein / 6.25
Glucose infusion rate
GIR = mg/(kg·min) = % × mL/h / (6 × kg)

Method

  1. Write down what is asked: a pump rate, a volume, kilocalories, grams of protein or water.
  2. Turn energy into volume with mL = kcal/(kcal/mL), and volume into protein with litres × g/L.
  3. Divide by the hours the feed actually runs for a rate, or by the number of feeds for a bolus.
  4. For needs, multiply kcal/kg or g/kg by the weight the rule names; find the ideal body weight with Devine: 50 or 45.5 + 2.3 × (inches − 60).
  5. For PN, find grams as % × mL/100, then use 3.4 kcal/g for dextrose, 4 kcal/g for amino acids and the stated kcal/mL for lipid.

IV fluids & fluid balance

Holliday–Segar per hour
4 mL/kg (first 10 kg) + 2 mL/kg (next 10 kg) + 1 mL/kg (each kg above 20)
Holliday–Segar per day
100 / 50 / 20 mL/kg for the same bands
Fluid balance
intake − output
Ice chips
count as half their volume
Urine output
mL/kg/h = mL / (kg × h)
Infusion time
time (h) = volume left (mL) / rate (mL/h)
Volume infused
mL = rate × time

2Practice problems

1.Enteral & parenteral nutrition calculationsMedium
44 g/L1.3 g/kg/day70 mL/h70 kg24 h/dayΔP = ? g

Practice exercise (made-up values, not clinical guidance). A 70 kg patient needs 1.3 g of protein per kg a day. The tube feed contains 44 g of protein per litre and runs at 70 mL/h for 24 hours a day. How many grams of extra protein ΔP a day are still needed? Round to one decimal place.

70 kg1.3 g/kg/day44 g/L70 mL/h · 24 h
ΔP = g/day
2.Enteral & parenteral nutrition calculationsHard
24 hdextrose 25%1200 mLamino acids 4.25%1200 mLlipid 20%100 mL · 2 kcal/mLN = protein/6.25NPC : N = ? : 1

Practice exercise (made-up values, not clinical guidance). Over 24 hours a patient receives 1200 mL of parenteral nutrition with final concentrations of 25% dextrose and 4.25% amino acids, plus 100 mL of 20% lipid emulsion (2 kcal/mL). Find the non-protein kilocalorie to nitrogen ratio NPC : N (the number x in x : 1). Round to the nearest whole number.

1200 mLdextrose 25%amino acids 4.25%lipid 100 mL · 2 kcal/mL
NPC : N =
3.IV fluids & fluid balanceMedium
IntakeOutput8-hour shiftmilk100 mLwater240 mLjuice120 mLIV infusion125 mL/h × 8 hIV antibiotic2 × 100 mLurine225 mLurine500 mLwound drain140 mL

Practice exercise (made-up values, not clinical guidance). The record shows a patient's intake and output for one 8-hour shift. The IV infusion ran at the rate shown for the whole shift. Find the total intake I in mL.

milk: 100 mLwater: 240 mLjuice: 120 mLIV infusion: 125 mL/h × 8 hIV antibiotic: 2 × 100 mL
I = mL
4.IV fluids & fluid balanceHard
1000 mL500 mL infused50 mL/h09:00t = ? h

Practice exercise (made-up values, not clinical guidance). A 1000 mL bag runs by pump at 50 mL/h. At 09:00, 500 mL have already been infused. How many hours t until the bag is empty? Round to one decimal place.

1000 mL500 mL infused50 mL/h
t = h

3Solutions

1.Enteral & parenteral nutrition calculations

Answer: ΔP = 17.1 g/day

Needs and free water: energy needs are often estimated as kcal/kg/day × weight and protein needs as g/kg/day × weight. A formula is only partly water, so its free water = volume × water fraction; water flushes make up the rest of the daily fluid goal. Ideal body weight (Devine): IBW = 50 kg + 2.3 kg for every inch over 5 feet (60 in) for men, and 45.5 kg + 2.3 kg per inch over 60 in for women; 1 in = 2.54 cm. The formula is meant for adults at least 152.4 cm (5 ft) tall. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Protein needed

1.3·70 = 91 g/day

Protein from the feed

70·24 = 1680 mL = 1.68 L
1.68·44 = 73.92 g/day

Shortfall

ΔP = 91 − 73.92 = 17.08 ≈ 17.1 g/day

Answer

ΔP = 17.1 g/day
2.Enteral & parenteral nutrition calculations

Answer: NPC : N = 150

Parenteral nutrition: dextrose provides 3.4 kcal/g, amino acids 4 kcal/g and lipid emulsion the kcal/mL stated (2 kcal/mL for 20%, 1.1 kcal/mL for 10%). Grams = % × mL/100. Non-protein kcal (NPC) = dextrose + lipid kcal; nitrogen = protein/6.25. The glucose infusion rate (GIR) in mg/kg/min = dextrose mg/(kg × minutes). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Grams of dextrose and amino acids

dextrose: 25·1200/100 = 300 g
amino acids: 4.25·1200/100 = 51 g

Kilocalories per component

dextrose: 300·3.4 = 1020 kcal
amino acids: 51·4 = 204 kcal
lipid: 100·2 = 200 kcal

Non-protein kcal and nitrogen

NPC = 1020 + 200 = 1220 kcal
N = 51/6.25 = 8.16 g

Ratio

NPC : N = 1220/8.16 = 149.5 ≈ 150 : 1

Answer

NPC : N = 150

Ratios of about 150 : 1 are typical for stable patients; lower ratios give relatively more protein.

3.IV fluids & fluid balance

Answer: I = 1660 mL

Intake and output: intake counts everything that goes in (oral fluids, IV infusions, IV medications and flushes, tube feeds); ice chips count as half their volume. Output counts urine, drains, vomit and other losses. Balance = total intake − total output; a negative balance is a net loss. The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Add the intake

oral: 100 + 240 + 120 = 460 mL
IV infusion: 125·8 = 1000 mL
IV antibiotic: 2·100 = 200 mL
I = 1660 mL

Answer

I = 1660 mL
4.IV fluids & fluid balance

Answer: t = 10 h

Infusion time: time (h) = volume to infuse (mL)/rate (mL/h); use the volume still left in the bag, not the bag size. Volume infused = rate × time. Convert decimal hours to hours and minutes with the fraction × 60 (0.5 h = 30 min, not 50 min). The numbers are for practice only; at the bedside always follow local protocols and have high-risk doses double-checked.

Volume left

1000 − 500 = 500 mL

Time

t = 500/50 = 10 h

Answer

t = 10 h

That is about 10 h 00 min, so the bag runs out at about 19:00.

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