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1Formulas and methods
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
2Practice problems
1.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
2.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1ventricular tachycardia
2sinus bradycardia
3idioventricular rhythm
4asystole
3.Human physiologyMedium
Which hormonal event triggers ovulation?
AA rise in progesterone from the corpus luteum
BA surge of luteinising hormone (LH)
CA surge of prolactin
DA fall in oestrogen
4.Human physiologyHard
Which spirometry finding is typical of chronic obstructive pulmonary disease (COPD)?
AIncreased peak expiratory flow
BNormal FEV1 with low FVC
CFEV1/FVC ratio below 0.7
DFEV1/FVC ratio above 0.9 with low FVC
3Solutions
1.ECG rhythm strip interpretation
Answer: QTc = 0.417 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 23 × 0.04 = 0.92 s
Bazett’s formula
QTc = 0.40/√0.92 = 0.40/0.9592 = 0.417 s
Answer
QTc = 0.417 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (417 ms)
2.ECG rhythm strip interpretation
Answer: idioventricular rhythm
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: R–R = 48 small boxes, 1500 ÷ 48 ≈ 31 per minute.
2. Rhythm: regular, every R–R is 1.92 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.20 s, wide (0.12 s or more) and bizarre, with the T wave pointing the other way.
Interpretation
idioventricular rhythm
Answer
idioventricular rhythm
An idioventricular rhythm is an escape rhythm: the ventricles take over because the pacemakers above them have failed.
3.Human physiology
Answer: B · A surge of luteinising hormone (LH)
Why this is the answer
Rising oestrogen from the dominant follicle triggers an LH surge from the anterior pituitary, which causes ovulation about a day later.
Answer
B · A surge of luteinising hormone (LH)
4.Human physiology
Answer: C · FEV1/FVC ratio below 0.7
Why this is the answer
Narrowed airways slow expiration, so FEV1 falls more than FVC and the ratio drops below 0.7. In COPD this is not fully reversed by bronchodilators.