Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient on furosemide has a serum potassium of 3.0 mmol/L (3.0 mEq/L). Which symptoms may this cause?
ATingling around the lips and painful spasm of the hands
BMuscle weakness, cramps and an irregular pulse
CFacial flushing, fever and a skin rash
DSevere headache and a stiff neck
2.Med-surg: cardiovascular & respiratoryHard
A ventilated patient in critical care is at risk of ventilator-associated pneumonia. Which nursing measure helps reduce this risk?
AChanging the ventilator tubing every few hours
BAvoiding mouth care to prevent gum bleeding
CKeeping the head of the bed raised to 30–45°
DKeeping the patient flat to protect the endotracheal tube
3.Med-surg: neuro, endocrine & renalMedium
Why are tacrolimus blood levels checked regularly?
AToo high harms the kidney; too low risks rejection
BThe drug only works if levels are as high as possible
CThe levels show whether the patient has diabetes
DThe levels show how much urine the kidney is making
4.Med-surg: neuro, endocrine & renalHard
A patient with an external ventricular drain sat up in bed without help. The drain stayed at its old height, and the drainage bag filled quickly. The patient now has a headache. What is the concern?
AAn infected drain, so the dressing should be removed
BUnderdrainage, so the drain should be lowered further
COverdrainage of CSF, so act per protocol and inform the team
DNo concern, because more drainage always lowers the ICP safely
5.Med-surg: GI, perioperative & oncologyMedium
Why are patients with diabetes often placed early on the operating list?
ABecause they need to go home before midday
BBecause their surgery always takes longer than others
CBecause their wounds heal faster in the morning
DTo shorten fasting and reduce swings in blood glucose
6.Med-surg: GI, perioperative & oncologyHard
Which preoperative task can a registered nurse usually delegate to a healthcare assistant (nursing assistant)?
ATeaching the patient how to use a PCA pump
BDeciding whether abnormal results need reporting
CAssessing the patient's understanding of the surgery
DRecording baseline vital signs
7.Clinical nursingMedium
Which is a recognised risk factor for postoperative nausea and vomiting?
ABeing male
BUse of opioids after surgery
CA short operation under local anaesthetic
DBeing a smoker
8.Clinical nursingHard
During CPR for asystole, when should adrenaline (epinephrine) be given according to standard adult guidelines?
AAs soon as IV or IO access is obtained, then every 3–5 minutes
BNever, because asystole is not treated with drugs
COnly once the patient has a pulse again
DOnly after three shocks have been delivered by the defibrillator
9.Lab values & electrolytesMedium
A patient on a heparin infusion has an aPTT below the target range on the protocol. What should the nurse do?
ASwitch the infusion to oral warfarin without a prescription
BStop the infusion and give protamine sulfate as quickly as possible
CContinue the same rate and recheck the aPTT in a few days
DAdjust the rate as the protocol directs and recheck as scheduled
10.Lab values & electrolytesHard
A patient on long-term amiodarone has fatigue and weight gain. TSH is 11 mIU/L and the free T4 is low. What is the most likely explanation?
AAmiodarone-induced hyperthyroidism
BAmiodarone-induced hypothyroidism
CSecondary hypothyroidism from pituitary failure
DA normal response to amiodarone needing no action
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.53, PaCO₂ 50 mmHg (6.7 kPa) and HCO₃⁻ 40 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.53PaCO₂ 50 mmHg (6.7 kPa)HCO₃⁻ 40 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.29, PaCO₂ 62 mmHg (8.3 kPa), HCO₃⁻ 29 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.29PaCO₂ 62 mmHg (8.3 kPa)HCO₃⁻ 29 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 2:1 conduction
2normal sinus rhythm
3atrial fibrillation
4atrial flutter, 4:1 conduction
14.ECG rhythm strip interpretationHard
This lead II strip shows second-degree AV block type I (Wenckebach). Measure the PR interval of the last conducted beat before a non-conducted P wave (the longest PR), in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
longest PR = s
15.Prioritization & delegationMedium
A patient with diabetes is unresponsive and has a blood glucose of 40 mg/dL (2.2 mmol/L). What should the nurse do first?
AGive IV dextrose or glucagon as prescribed
BGive the scheduled dose of insulin
CWait 15 minutes and recheck the glucose
DPour orange juice into the patient’s mouth
16.Prioritization & delegationHard
Four laboratory results come back at once. Which one should the nurse report first?
ACreatinine 1.3 mg/dL in an older adult, unchanged from last week
BHemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed
CGlucose 180 mg/dL after a meal in a patient with diabetes
DPotassium 3.4 mEq/L in a patient on a diuretic
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Muscle weakness, cramps and an irregular pulse
Why this is the answer
The adult reference range is about 3.5–5.0 mmol/L, so 3.0 mmol/L is low. Hypokalaemia causes weakness, cramps, constipation and arrhythmias, with flattened T waves and U waves on the ECG. Tingling lips and hand spasm suggest low calcium.
Answer
B · Muscle weakness, cramps and an irregular pulse
2.Med-surg: cardiovascular & respiratory
Answer: C · Keeping the head of the bed raised to 30–45°
Why this is the answer
Ventilator care bundles include head elevation of 30–45°, regular oral care, daily assessment of readiness to wean (sedation holds) and subglottic secretion drainage where available. Frequent circuit changes are not recommended unless the tubing is soiled or faulty.
Answer
C · Keeping the head of the bed raised to 30–45°
3.Med-surg: neuro, endocrine & renal
Answer: A · Too high harms the kidney; too low risks rejection
Why this is the answer
Tacrolimus has a narrow therapeutic range and many interactions. High levels can cause nephrotoxicity, tremor and high glucose, while low levels risk rejection. Trough levels are taken before the morning dose.
Answer
A · Too high harms the kidney; too low risks rejection
4.Med-surg: neuro, endocrine & renal
Answer: C · Overdrainage of CSF, so act per protocol and inform the team
Why this is the answer
When the head rises above the drain level, CSF drains faster. Overdrainage can cause headache, collapse of the ventricles or a subdural bleed. The nurse follows the protocol (often clamping briefly and re-levelling) and informs the neurosurgical team.
Answer
C · Overdrainage of CSF, so act per protocol and inform the team
5.Med-surg: GI, perioperative & oncology
Answer: D · To shorten fasting and reduce swings in blood glucose
Why this is the answer
Shorter fasting reduces the risk of hypoglycaemia and makes it easier to restart normal eating and medicines. Glucose is monitored, and a variable-rate insulin infusion may be used for longer fasts.
Answer
D · To shorten fasting and reduce swings in blood glucose
6.Med-surg: GI, perioperative & oncology
Answer: D · Recording baseline vital signs
Why this is the answer
Trained assistants can record routine observations and report them. Assessment, teaching and interpreting results need registered nurse knowledge and judgement.
Answer
D · Recording baseline vital signs
7.Clinical nursing
Answer: B · Use of opioids after surgery
Why this is the answer
Known risk factors include opioids, female sex, being a non-smoker, previous PONV or motion sickness and longer general anaesthetics. High-risk patients may be given preventive antiemetics.
Answer
B · Use of opioids after surgery
8.Clinical nursing
Answer: A · As soon as IV or IO access is obtained, then every 3–5 minutes
Why this is the answer
In non-shockable rhythms, adrenaline is given as soon as possible and repeated every 3–5 minutes while CPR continues. In shockable rhythms it is given after the third shock in UK/European guidelines (after the second shock in AHA guidelines).
Answer
A · As soon as IV or IO access is obtained, then every 3–5 minutes
9.Lab values & electrolytes
Answer: D · Adjust the rate as the protocol directs and recheck as scheduled
Why this is the answer
A subtherapeutic aPTT means the patient is not fully anticoagulated and is at risk of clot extension. Weight-based heparin protocols specify a bolus and/or rate increase and when to recheck. The nurse follows the protocol and documents the change.
Answer
D · Adjust the rate as the protocol directs and recheck as scheduled
10.Lab values & electrolytes
Answer: B · Amiodarone-induced hypothyroidism
Why this is the answer
Amiodarone is rich in iodine and can cause either hypothyroidism or hyperthyroidism. A high TSH with a low free T4 shows primary hypothyroidism, so thyroid function is monitored before and during therapy; liver tests are monitored too.
Answer
B · Amiodarone-induced hypothyroidism
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.53: alkalaemia (above 7.45)
PaCO₂ 50 mmHg: high (35–45)
HCO₃⁻ 40 mmol/L: high (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: acute on chronic
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·2.2 = 26.2 mmol/L
chronic: 24 + 3.5·2.2 = 31.7 mmol/L
Compare
measured: 29 mmol/L → acute on chronic
Answer
acute on chronic
13.ECG rhythm strip interpretation
Answer: atrial flutter, 4:1 conduction
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 20 small boxes, 1500 ÷ 20 ≈ 75 per minute.
2. Rhythm: regular, every R–R is 0.80 s.
3. P waves: none; regular sawtooth flutter waves every 0.20 s (300 per minute), 4 for each QRS.
4. PR interval: not measurable.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
atrial flutter, 4:1 conduction
Answer
atrial flutter, 4:1 conduction
14.ECG rhythm strip interpretation
Answer:longest PR = 0.36 s
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
March out the P waves
P–P = 1.00 s, regular; one P wave in every 4 is not conducted
PR in each group
PR₁ = 0.18 s, PR₂ = 0.30 s, PR₃ = 0.36 s
Answer
longest PR = 0.36 s
The biggest step in PR comes between the first and second beats of a group; later steps are smaller, which is why the R–R intervals shorten before the pause.
15.Prioritization & delegation
Answer: A · Give IV dextrose or glucagon as prescribed
Why this is the answer
An unconscious patient must not be given anything by mouth because of aspiration risk. IV dextrose or glucagon raises the glucose quickly.
Answer
A · Give IV dextrose or glucagon as prescribed
16.Prioritization & delegation
Answer: B · Hemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed
Why this is the answer
A hemoglobin of 6.5 g/dL (65 g/L) in a bleeding patient shows severe anemia and may need urgent transfusion. The other results are mildly abnormal or stable.
Answer
B · Hemoglobin 6.5 g/dL (65 g/L) in a patient with a GI bleed