Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient who had a stroke has a weak swallow. Which measure most reduces the risk of aspiration pneumonia?
ALying flat for 30 minutes after eating to aid digestion
BGiving meals while the patient is drowsy
CGiving thin fluids quickly through a straw between meals
DA swallowing assessment and sitting upright for meals
2.Med-surg: cardiovascular & respiratoryHard
A patient with known peripheral arterial disease suddenly has a cold, white, painful foot with no pulses and numb toes. What is the priority?
AEncourage walking to open up the collateral circulation
BRaise the leg on pillows and warm the foot with a hot water bottle
CApply a compression bandage to improve the circulation
DEscalate at once as an emergency; keep the leg level, no heat
3.Med-surg: neuro, endocrine & renalMedium
A patient on peritoneal dialysis has gained weight and has higher glucose levels. Which part of the treatment is the likely cause?
ASodium lost into the dialysis fluid
BProtein lost into the dialysis fluid
CGlucose absorbed from the dialysis fluid
DAir entering the abdomen during exchanges
4.Med-surg: neuro, endocrine & renalHard
A patient with cranial diabetes insipidus starts desmopressin. Which complication should the nurse monitor for?
AHyperglycaemia
BSevere diarrhoea
CHyponatraemia
DHyperkalaemia
5.Med-surg: GI, perioperative & oncologyMedium
What is TENS?
AA pain score used for babies
BA type of epidural catheter inserted in theatre
CA strong opioid given through the skin as a weekly adhesive patch
DA device that sends mild electrical pulses through skin pads
6.Med-surg: GI, perioperative & oncologyHard
An hour after a line flush, a patient receiving parenteral nutrition has rigors and a temperature of 39.1 °C. What should the nurse suspect and do?
AA normal reaction; give paracetamol and continue the infusion
BLow blood glucose; give a sugary drink
CFluid overload; reduce the infusion rate only
DLine infection; escalate and take blood cultures
7.Clinical nursingMedium
Why is it important to prevent hypothermia during and after surgery?
AIt makes the patient wake up too quickly and become agitated in recovery
BIt causes high blood glucose only
CIt makes the patient's pain disappear
DIt increases the risk of wound infection, bleeding and cardiac complications
8.Clinical nursingHard
A patient's hypoglycaemia was caused by a sulfonylurea such as gliclazide or glipizide. Why might they need monitoring for longer than usual?
AThe drug makes glucose tablets and drinks ineffective
BThe drug causes rebound hyperglycaemia later the same day
CSulfonylureas only work at night
DSulfonylureas act for a long time, so hypoglycaemia can recur
9.Lab values & electrolytesMedium
Which laboratory value best reflects the cause of confusion in a patient with severe liver disease and a flapping tremor?
AA raised serum ammonia
BA low serum potassium only
CA low serum lipase
DA raised troponin
10.Lab values & electrolytesHard
Which pattern of results fits SIADH?
ALow serum sodium, high serum osmolality and dilute urine
BHigh serum sodium, high serum osmolality and very dilute urine
CNormal sodium with very dilute urine
DLow serum sodium, low serum osmolality and concentrated urine
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 136 mmol/L, glucose 14 mmol/L and urea 20.6 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 136 mmol/Lglucose 14 mmol/Lurea 20.6 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.09, PaCO₂ 34 mmHg (4.5 kPa), HCO₃⁻ 10 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.09PaCO₂ 34 mmHg (4.5 kPa)HCO₃⁻ 10 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
A patient without a palpable pulse has this organised rhythm on the monitor (pulseless electrical activity). Which treatment do adult resuscitation guidelines name for it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1synchronised cardioversion
2immediate defibrillation
3CPR (non-shockable rhythm)
4transcutaneous pacing
15.Prioritization & delegationMedium
A swimmer is found unresponsive after diving into shallow water. Which method should the nurse use to open the airway?
ARaising the chin while bending the neck forward
BTurning the head to the side to drain water
CJaw thrust, keeping the head and neck in line
DHead-tilt, chin-lift with full neck extension
16.Prioritization & delegationHard
A trauma patient has an open leg fracture, absent breath sounds on one side, a trachea shifted to the other side and a falling blood pressure. Which problem is the priority?
AThe open fracture of the leg
BThe risk of wound infection
CThe pain from the fracture
DThe suspected tension pneumothorax
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · A swallowing assessment and sitting upright for meals
Why this is the answer
Patients with dysphagia need a formal swallowing assessment, food and fluid textures that are safe for them, sitting upright during and after meals and close supervision. Good oral hygiene also reduces the bacterial load that can be aspirated.
Answer
D · A swallowing assessment and sitting upright for meals
2.Med-surg: cardiovascular & respiratory
Answer: D · Escalate at once as an emergency; keep the leg level, no heat
Why this is the answer
Pain, pallor, pulselessness, paraesthesia, paralysis and a perishingly cold limb indicate acute limb ischaemia, usually from an embolus or thrombosis. Revascularisation within hours is needed to save the limb. Heat increases metabolic demand and can burn, elevation reduces arterial flow and compression is harmful.
Answer
D · Escalate at once as an emergency; keep the leg level, no heat
3.Med-surg: neuro, endocrine & renal
Answer: C · Glucose absorbed from the dialysis fluid
Why this is the answer
Standard PD fluids contain glucose to pull water out by osmosis. Some glucose is absorbed, adding calories and raising blood glucose. Glucose monitoring and diet advice are needed, and other solutions may be used.
Answer
C · Glucose absorbed from the dialysis fluid
4.Med-surg: neuro, endocrine & renal
Answer: C · Hyponatraemia
Why this is the answer
Desmopressin is a synthetic ADH analogue. If the patient continues drinking large amounts, water retention can cause hyponatraemia, with headache, confusion or seizures. Patients are advised to drink to thirst, and sodium, weight and fluid balance are monitored.
Answer
C · Hyponatraemia
5.Med-surg: GI, perioperative & oncology
Answer: D · A device that sends mild electrical pulses through skin pads
Why this is the answer
TENS is thought to reduce pain partly through the gate-control mechanism. It is non-invasive and patient-controlled, but is avoided over certain areas and with some implanted devices.
Answer
D · A device that sends mild electrical pulses through skin pads
6.Med-surg: GI, perioperative & oncology
Answer: D · Line infection; escalate and take blood cultures
Why this is the answer
Fever and rigors after flushing a central line suggest a catheter-related bloodstream infection. The nurse escalates urgently, takes cultures from the line and peripherally per policy, and starts sepsis care.
Answer
D · Line infection; escalate and take blood cultures
7.Clinical nursing
Answer: D · It increases the risk of wound infection, bleeding and cardiac complications
Why this is the answer
Inadvertent perioperative hypothermia impairs clotting and immune function and increases cardiac events and wound infection. Patients are warmed actively and their temperature monitored.
Answer
D · It increases the risk of wound infection, bleeding and cardiac complications
8.Clinical nursing
Answer: D · Sulfonylureas act for a long time, so hypoglycaemia can recur
Why this is the answer
Sulfonylureas stimulate insulin release and have a long duration of action. Hypoglycaemia can be prolonged or recur, so glucose is monitored closely after treatment.
Answer
D · Sulfonylureas act for a long time, so hypoglycaemia can recur
9.Lab values & electrolytes
Answer: A · A raised serum ammonia
Why this is the answer
A failing liver cannot convert ammonia into urea, so ammonia builds up and contributes to hepatic encephalopathy. Lactulose is commonly used to lower ammonia absorption from the gut.Checked against:Ammonia Levels · MedlinePlus (NIH) (2026); Loss of brain function - liver disease · MedlinePlus (NIH) (2025)
Answer
A · A raised serum ammonia
10.Lab values & electrolytes
Answer: D · Low serum sodium, low serum osmolality and concentrated urine
Why this is the answer
Excess antidiuretic hormone causes water retention, diluting the blood (low sodium and osmolality), while the urine is inappropriately concentrated. High sodium with very dilute urine is the pattern of diabetes insipidus.Checked against:Syndrome of inappropriate antidiuretic hormone secretion · MedlinePlus (NIH) (2025)
Answer
D · Low serum sodium, low serum osmolality and concentrated urine
11.Arterial blood gas interpretation
Answer: Osm = 307 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·136 + 14 + 20.6 = 306.6 ≈ 307 mOsm/kg
Answer
Osm = 307 mOsm/kg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·10 + 8 = 23 → 21–25 mmHg
Compare
measured: 34 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: QTc = 0.48 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 11.5 × 0.04 = 0.46 s
RR = 22 × 0.04 = 0.88 s
Fridericia’s formula
QTc = 0.46/∛0.88 = 0.46/0.9583 = 0.48 s
Answer
QTc = 0.48 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (480 ms)
14.ECG rhythm strip interpretation
Answer: CPR (non-shockable rhythm)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 13 small boxes, 1500 ÷ 13 ≈ 115 per minute.
2. Rhythm: regular, every R–R is 0.52 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
sinus tachycardia
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
CPR (non-shockable rhythm)
Answer
CPR (non-shockable rhythm)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: C · Jaw thrust, keeping the head and neck in line
Why this is the answer
A diving injury may damage the cervical spine. A jaw thrust opens the airway with little neck movement; if it fails, the airway still takes priority.
Answer
C · Jaw thrust, keeping the head and neck in line
16.Prioritization & delegation
Answer: D · The suspected tension pneumothorax
Why this is the answer
A shifted trachea, absent breath sounds and hypotension suggest tension pneumothorax, which threatens breathing and circulation within minutes. The fracture is important, but it comes after the immediate life threat.