Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which exercise advice is recommended for intermittent claudication?
AComplete bed rest until the leg pain has gone for at least a month
BSupervised walking until pain is near maximal, then rest and repeat
CStopping walking at the very first twinge of pain each time
DWalking only on days when the legs feel warm and painless
2.Med-surg: cardiovascular & respiratoryHard
A patient with small-cell lung cancer becomes confused. Sodium is 122 mmol/L (122 mEq/L) with concentrated urine, and there are no signs of dehydration. What is the most likely cause?
ACranial diabetes insipidus from brain metastases
BSevere dehydration from poor oral intake
CSyndrome of inappropriate ADH secretion
DExcess salt in the diet over several weeks
3.Med-surg: neuro, endocrine & renalMedium
Which criterion for acute kidney injury (KDIGO) relates to urine output?
AAny change in the colour of the urine
BBelow 2 mL/kg/h for 1 hour
CBelow 0.5 mL/kg/h for 6 hours or more
DBelow 1 L in 24 hours whatever the intake
4.Med-surg: neuro, endocrine & renalHard
A patient on peritoneal dialysis notices that less fluid drains out than was put in. They have not opened their bowels for four days, and the effluent is clear. What is the most likely cause?
ADialysate given too cold
BNormal absorption with no action needed
CConstipation obstructing outflow
DBacterial peritonitis
5.Med-surg: GI, perioperative & oncologyMedium
Why is thiamine given to patients with alcohol dependence admitted to hospital?
ATo treat the cirrhosis directly
BTo reduce the craving for alcohol
CTo prevent bleeding from varices
DTo prevent Wernicke's encephalopathy
6.Med-surg: GI, perioperative & oncologyHard
A patient arrives in the anaesthetic room without an identity band. What should the nurse do?
AProceed and add a band once in recovery
BProceed because the patient can say their name
CStop and confirm identity, then apply a band
DUse the spare identity band from the front of the patient's notes folder
7.Clinical nursingMedium
A patient receives IV furosemide for fluid overload. Which findings show the treatment is working?
AA rise in weight and more lung crackles
BFalling urine output, new ankle swelling and a rise in weight
CA rise in blood pressure and a new cough
DIncreased urine output, less breathlessness and a falling weight
8.Clinical nursingHard
Which finding most strongly suggests a pulmonary embolism in a postoperative patient?
ASlow heart rate with high blood pressure
BGradual onset of cough with yellow sputum and mild fever over a week
CSudden breathlessness and pleuritic chest pain with tachycardia
DWheeze that improves with salbutamol
9.Lab values & electrolytesMedium
When should a blood sample for a digoxin level be drawn to be interpreted correctly?
AAt any time, because digoxin levels do not change during the day
BOnly after a meal, because food is needed for absorption
CWithin 30 minutes after an oral dose to show the peak level
DAt least 6–8 hours after a dose, often just before the next one
10.Lab values & electrolytesHard
A 68-year-old man has fatigue, a hemoglobin of 9.8 g/dL (98 g/L), an MCV of 72 fL and a low ferritin. He eats a normal diet. What is the most important next step?
ALook for a source of blood loss in the gut
BStart vitamin B12 injections
CRepeat the blood count in one year
DGive iron and do no further tests at all
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.23, PaCO₂ 42 mmHg (5.6 kPa) and HCO₃⁻ 17 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.23PaCO₂ 42 mmHg (5.6 kPa)HCO₃⁻ 17 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 31 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 31 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1torsades de pointes
2atrial flutter, 2:1 conduction
3ventricular fibrillation
4idioventricular rhythm
15.Prioritization & delegationMedium
Which newborn finding needs prompt reporting?
AJaundice that appears within the first 24 hours
BMild jaundice that first appears on the third day
CMilia (small white spots) on the nose
DBluish hands and feet in the first hours
16.Prioritization & delegationHard
After handover on a medical unit, which patient should the nurse see first?
APneumonia on 2 L/min oxygen, SpO₂ 93%, talking in full sentences
BDeep vein thrombosis on a heparin infusion, aPTT in the target range
CDay 2 after a hernia repair, pain 6/10, oral analgesic due in 20 minutes, wants it now
Answer: B · Supervised walking until pain is near maximal, then rest and repeat
Why this is the answer
Supervised exercise programmes, walking to near-maximal claudication pain, resting and repeating for about 30 minutes several times a week, improve walking distance. With smoking cessation, an antiplatelet and a statin, this is first-line management.
Answer
B · Supervised walking until pain is near maximal, then rest and repeat
2.Med-surg: cardiovascular & respiratory
Answer: C · Syndrome of inappropriate ADH secretion
Why this is the answer
Small-cell lung cancer can secrete ADH, causing water retention and dilutional hyponatraemia (normal sodium about 135–145 mmol/L). Urine is inappropriately concentrated and the patient is not dry. Fluid restriction and treating the cancer are the main measures; sodium is corrected slowly to avoid osmotic demyelination.
Answer
C · Syndrome of inappropriate ADH secretion
3.Med-surg: neuro, endocrine & renal
Answer: C · Below 0.5 mL/kg/h for 6 hours or more
Why this is the answer
KDIGO defines AKI as a creatinine rise of ≥26.5 µmol/L (0.3 mg/dL) within 48 hours, a rise to ≥1.5 times baseline within 7 days, or urine output below 0.5 mL/kg/h for 6 hours. Accurate fluid balance charts are therefore essential.
Answer
C · Below 0.5 mL/kg/h for 6 hours or more
4.Med-surg: neuro, endocrine & renal
Answer: C · Constipation obstructing outflow
Why this is the answer
Poor outflow is often caused by constipation, catheter kinking or catheter displacement. Changing position, checking clamps and tubing and treating constipation often help; it should be reported. If it persists, imaging checks the catheter position. Clear effluent makes peritonitis less likely.
Answer
C · Constipation obstructing outflow
5.Med-surg: GI, perioperative & oncology
Answer: D · To prevent Wernicke's encephalopathy
Why this is the answer
Thiamine deficiency is common in alcohol dependence and can cause Wernicke's encephalopathy (confusion, ataxia, eye signs). Thiamine is given early, ideally before or with glucose, as glucose can worsen deficiency.
Answer
D · To prevent Wernicke's encephalopathy
6.Med-surg: GI, perioperative & oncology
Answer: C · Stop and confirm identity, then apply a band
Why this is the answer
Correct identification before anaesthesia prevents wrong-patient surgery. The process stops until identity is confirmed with the patient and records and a band is applied, following the checklist.
Answer
C · Stop and confirm identity, then apply a band
7.Clinical nursing
Answer: D · Increased urine output, less breathlessness and a falling weight
Why this is the answer
Effective diuresis increases urine output and reduces congestion, so breathing improves and weight falls. Electrolytes, renal function and blood pressure are also monitored.
Answer
D · Increased urine output, less breathlessness and a falling weight
8.Clinical nursing
Answer: C · Sudden breathlessness and pleuritic chest pain with tachycardia
Why this is the answer
PE typically presents with sudden dyspnoea, chest pain on breathing, tachycardia, low oxygen saturation and sometimes haemoptysis or collapse.
Answer
C · Sudden breathlessness and pleuritic chest pain with tachycardia
9.Lab values & electrolytes
Answer: D · At least 6–8 hours after a dose, often just before the next one
Why this is the answer
Digoxin distributes slowly from blood to tissues, so a sample taken too soon after a dose is falsely high. Levels are drawn at least 6–8 hours after a dose, commonly as a trough before the next dose.
Answer
D · At least 6–8 hours after a dose, often just before the next one
10.Lab values & electrolytes
Answer: A · Look for a source of blood loss in the gut
Why this is the answer
Iron deficiency in an older man or a postmenopausal woman suggests chronic blood loss, often from the gastrointestinal tract, including colorectal cancer. Iron is started, but endoscopy or colonoscopy is needed to find the cause.
Answer
A · Look for a source of blood loss in the gut
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.23: acidaemia (below 7.35)
PaCO₂ 42 mmHg: normal (35–45)
HCO₃⁻ 17 mmol/L: low (22–26)
Compensation
Clinically, also check the expected compensation: Winter’s formula expects PaCO₂ 31.5–35.5 mmHg, so the measured 42 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: PaCO₂ = 42.7 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·31 + 21 = 42.7 mmHg
Answer
PaCO₂ = 42.7 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: QTc = 0.4 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 25 × 0.04 = 1.00 s
Fridericia’s formula
QTc = 0.40/∛1.00 = 0.40/1 = 0.4 s
Answer
QTc = 0.4 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (400 ms)
14.ECG rhythm strip interpretation
Answer: torsades de pointes
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: very fast, the complexes are about 6 small boxes apart (about 250 per minute).
2. Rhythm: fast and roughly regular, but the height and direction of the complexes change in a repeating spindle pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: wide and polymorphic; the complexes twist around the baseline, pointing up for a few beats and then down.
Interpretation
torsades de pointes
Answer
torsades de pointes
Torsades de pointes is a polymorphic VT linked to a prolonged QT interval. This is identification practice only.
15.Prioritization & delegation
Answer: A · Jaundice that appears within the first 24 hours
Why this is the answer
Jaundice in the first 24 hours is not physiological and may point to hemolysis or infection. Mild jaundice after the first day, milia and acrocyanosis are common, expected findings.
Answer
A · Jaundice that appears within the first 24 hours
16.Prioritization & delegation
Answer: D · New atrial fibrillation, heart rate 150/min, blood pressure 86/50 mmHg, dizzy
Why this is the answer
Rapid atrial fibrillation with hypotension and dizziness means the heart is not pumping enough blood; the patient is unstable. The other patients are within target or have predictable needs.
Answer
D · New atrial fibrillation, heart rate 150/min, blood pressure 86/50 mmHg, dizzy