Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A chest drain water-seal chamber bubbles continuously, even when the patient is not coughing. What does this suggest?
AAn air leak from the lung or from the drainage system
BThe suction source has been switched off
CThe lung has fully re-expanded and the drain is ready to remove
DThe drain is blocked by a clot in the tubing
2.Med-surg: cardiovascular & respiratoryHard
A patient with crushing chest pain has ST elevation in leads V1–V4. Which coronary artery is most likely blocked?
AThe left anterior descending artery
BThe right coronary artery and its branches
CThe left subclavian artery
DThe circumflex artery
3.Med-surg: neuro, endocrine & renalMedium
Why is all urine strained in a patient with suspected kidney stones?
ATo measure the urine volume more accurately
BTo stop the stone from blocking the toilet
CTo catch the stone so it can be analysed
DTo remove blood clots before testing
4.Med-surg: neuro, endocrine & renalHard
A patient with an insulin pump is admitted with nausea, a glucose of 19 mmol/L (342 mg/dL) and blood ketones of 3.1 mmol/L. What is the priority?
AGive an antiemetic only, because nausea is causing the high glucose
BIncrease the pump rate and recheck the ketones in 12 hours
CDisconnect the pump and give no insulin until the ketones clear
DSuspect failed insulin delivery and give insulin by another route
5.Med-surg: GI, perioperative & oncologyMedium
Which task for a stable patient with an established ileostomy can usually be delegated to a trained healthcare assistant (nursing assistant)?
ADeciding whether IV fluids are needed
BTeaching the patient about high-output risks
CAssessing the stoma for signs of necrosis
DEmptying the pouch and measuring the output
6.Med-surg: GI, perioperative & oncologyHard
Why is folinic acid (leucovorin) given after high-dose methotrexate?
ATo treat the patient's anaemia only
BTo increase the anticancer effect on the tumour
CTo prevent hair loss during treatment
DTo rescue normal cells from methotrexate toxicity
7.Clinical nursingMedium
A patient with heart failure has pink, frothy sputum and crackles throughout both lungs. What is happening?
AAsthma attack
BPneumothorax
CAcute pulmonary oedema
DUpper gastrointestinal bleeding
8.Clinical nursingHard
A severely hypothermic patient is in cardiac arrest. Why is resuscitation usually continued until they are rewarmed?
AAdrenaline works better in cold patients
BThe cold protects the brain, so recovery may be possible after long resuscitation
CCold patients cannot be defibrillated at all, so CPR is the only possible treatment
DHypothermia always causes brain death quickly
9.Lab values & electrolytesMedium
Why must vitamin B12 deficiency be ruled out before treating macrocytic anemia with folic acid alone?
AFolic acid causes iron overload when B12 levels are low
BFolic acid makes B12 deficiency anemia much worse within a few days
CFolic acid blocks the absorption of all B12 from the diet
DFolic acid can fix the anemia while B12-related nerve damage continues
10.Lab values & electrolytesHard
Three days after starting haloperidol, a patient has a temperature of 40 °C, severe muscle rigidity and confusion. Which laboratory result would the nurse expect?
AA very high creatine kinase (CK)
BA very high serum lithium
CA very low white cell count
DA very low serum sodium
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.56, PaCO₂ 37 mmHg (4.9 kPa) and HCO₃⁻ 32 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.56PaCO₂ 37 mmHg (4.9 kPa)HCO₃⁻ 32 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.17, PaCO₂ 40 mmHg (5.3 kPa), HCO₃⁻ 14 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.17PaCO₂ 40 mmHg (5.3 kPa)HCO₃⁻ 14 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2ventricular bigeminy
3normal sinus rhythm
4sinus rhythm with PVCs
14.ECG rhythm strip interpretationHard
A patient without a palpable pulse has this organised rhythm on the monitor (pulseless electrical activity). Which treatment do adult resuscitation guidelines name for it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1synchronised cardioversion
2immediate defibrillation
3transcutaneous pacing
4CPR (non-shockable rhythm)
15.Prioritization & delegationMedium
On a mixed medical unit, which patient should the nurse see first?
AA patient with a mild tension headache who is asking for acetaminophen
BA patient with depression who has given away his belongings and has a suicide plan
CA patient asking for written information about tomorrow’s discharge
DA patient with hypertension whose blood pressure is 136/84 mmHg
16.Prioritization & delegationHard
An older patient has bruises of different ages and seems frightened when a relative visits. What is the nurse’s priority?
ATell the patient she must leave home and go to live somewhere else
BAsk the relative directly in front of the patient whether they hit her
CIgnore it, because older people bruise easily
DEnsure the patient’s safety, document the findings and report as required
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · An air leak from the lung or from the drainage system
Why this is the answer
Intermittent bubbling on expiration or coughing is expected while a pneumothorax drains. Continuous bubbling suggests a persistent air leak from the lung (such as a bronchopleural fistula) or from a loose connection or a tube that has slipped out. Check the system from the patient downwards and report it.
Answer
A · An air leak from the lung or from the drainage system
2.Med-surg: cardiovascular & respiratory
Answer: A · The left anterior descending artery
Why this is the answer
ST elevation in V1–V4 indicates an anteroseptal STEMI, usually from LAD occlusion. Anterior MIs damage a large area of muscle and carry a high risk of heart failure and arrhythmias. Leads II, III and aVF suggest an inferior MI, usually from the right coronary artery.
Answer
A · The left anterior descending artery
3.Med-surg: neuro, endocrine & renal
Answer: C · To catch the stone so it can be analysed
Why this is the answer
A passed stone can be sent for analysis. Its composition guides diet and drug advice to prevent recurrence. Straining also confirms that the stone has passed.
Answer
C · To catch the stone so it can be analysed
4.Med-surg: neuro, endocrine & renal
Answer: D · Suspect failed insulin delivery and give insulin by another route
Why this is the answer
Rising ketones in a pump user suggest that insulin delivery has failed, for example from a kinked cannula or an empty reservoir. Insulin must be given by pen or IV, and DKA treatment started if criteria are met. The site and pump are checked.
Answer
D · Suspect failed insulin delivery and give insulin by another route
5.Med-surg: GI, perioperative & oncology
Answer: D · Emptying the pouch and measuring the output
Why this is the answer
Emptying and measuring output is a routine task. Assessment of the stoma, teaching and decisions about treatment remain with the registered nurse, who reviews the recorded output.
Answer
D · Emptying the pouch and measuring the output
6.Med-surg: GI, perioperative & oncology
Answer: D · To rescue normal cells from methotrexate toxicity
Why this is the answer
Methotrexate inhibits dihydrofolate reductase. Timed folinic acid bypasses this block in normal cells, reducing toxicity such as mucositis and myelosuppression, while methotrexate levels and kidney function are monitored.
Answer
D · To rescue normal cells from methotrexate toxicity
7.Clinical nursing
Answer: C · Acute pulmonary oedema
Why this is the answer
Acute pulmonary oedema causes severe breathlessness, crackles and frothy sputum. Sit the patient up, give oxygen and call urgently for medical help; diuretics are commonly given.
Answer
C · Acute pulmonary oedema
8.Clinical nursing
Answer: B · The cold protects the brain, so recovery may be possible after long resuscitation
Why this is the answer
Hypothermia reduces the brain's oxygen needs, and good recoveries have occurred after long resuscitation. Death is usually not confirmed until the patient has been rewarmed, unless injuries are clearly not survivable.
Answer
B · The cold protects the brain, so recovery may be possible after long resuscitation
9.Lab values & electrolytes
Answer: D · Folic acid can fix the anemia while B12-related nerve damage continues
Why this is the answer
Folic acid can improve the blood picture in B12 deficiency but does not prevent nerve damage. Giving folate alone can therefore mask the deficiency while neurological damage progresses. Both levels are checked before treatment.
Answer
D · Folic acid can fix the anemia while B12-related nerve damage continues
10.Lab values & electrolytes
Answer: A · A very high creatine kinase (CK)
Why this is the answer
These signs suggest neuroleptic malignant syndrome, a medical emergency. Muscle rigidity releases CK, often to very high levels, and the white count is often raised. Myoglobin can damage the kidneys. The antipsychotic is stopped and supportive care is started.
Answer
A · A very high creatine kinase (CK)
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.56: alkalaemia (above 7.45)
PaCO₂ 37 mmHg: normal (35–45)
HCO₃⁻ 32 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 41.4–45.4 mmHg, so the measured 37 mmHg points to an additional respiratory alkalosis (a mixed disorder). The answer above is the ROME exam classification.
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·14 + 8 = 29 → 27–31 mmHg
Compare
measured: 40 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: ventricular bigeminy
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: regularly irregular, a short and a long R–R alternate (0.42 s and 1.10 s).
3. P waves: upright before every narrow QRS; none before the early wide beats.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s in the sinus beats; the early beats are wide (0.14 s) and bizarre, with the T wave pointing the other way.
Interpretation
ventricular bigeminy
Answer
ventricular bigeminy
14.ECG rhythm strip interpretation
Answer: CPR (non-shockable rhythm)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 28 small boxes, 1500 ÷ 28 ≈ 54 per minute.
2. Rhythm: regular, every R–R is 1.12 s.
3. P waves: inverted, just before each QRS.
4. PR interval: 0.10 s, shorter than 0.12 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
junctional rhythm
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
CPR (non-shockable rhythm)
Answer
CPR (non-shockable rhythm)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: B · A patient with depression who has given away his belongings and has a suicide plan
Why this is the answer
Giving away belongings and having a plan are warning signs of suicide, an immediate safety threat. The other patients are stable and their needs can wait.
Answer
B · A patient with depression who has given away his belongings and has a suicide plan
16.Prioritization & delegation
Answer: D · Ensure the patient’s safety, document the findings and report as required
Why this is the answer
Unexplained bruises of different ages and fear of a carer can suggest abuse. The nurse makes sure the patient is safe, documents objectively and reports according to law and policy.
Answer
D · Ensure the patient’s safety, document the findings and report as required