Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which set of side effects is typical of thiazide or thiazide-like diuretics such as indapamide?
AHigh sodium and magnesium, with low blood glucose
BHigh potassium and sodium, low uric acid and low blood glucose
CLow potassium and sodium, raised uric acid and raised glucose
DDry cough, taste disturbance and swelling of the lips
2.Med-surg: cardiovascular & respiratoryHard
After chest trauma, a patient is hypotensive with reduced breath sounds on the left. Which finding suggests a haemothorax rather than a tension pneumothorax?
ADullness to percussion on the affected side
BDistended neck veins
CHyper-resonance on the affected side
DTrachea pushed away from the affected side
3.Med-surg: neuro, endocrine & renalMedium
A patient with Graves' eye disease has gritty eyes and swelling around them in the morning. Which advice is most appropriate?
AUse lubricating drops and sleep with the head raised
BSmoking more will not affect the eyes
CRub the eyes firmly each morning to reduce the swelling
DStay in bright sunlight to dry the eyes
4.Med-surg: neuro, endocrine & renalHard
A patient with a severe head injury does not open the eyes, and in response to pain the arms extend and rotate inwards with the legs extended. What does this indicate?
AA normal withdrawal response to a painful stimulus
BExtensor (decerebrate) posturing: severe brainstem injury
CA focal seizure that will stop without any treatment
DFlexor (decorticate) posturing, a sign of mild cortical injury
5.Med-surg: GI, perioperative & oncologyMedium
What is anticipatory nausea in chemotherapy?
ANausea triggered by reminders of treatment before it is given
BNausea caused by low blood glucose
CNausea caused only by the smell of food
DNausea that starts about a week after each cycle and lasts for days
6.Med-surg: GI, perioperative & oncologyHard
Which medicine commonly needs enteral feeds paused before and after each dose because the feed reduces its absorption?
ALactulose
BParacetamol
COmeprazole liquid
DPhenytoin
7.Clinical nursingMedium
A patient's low potassium does not improve despite potassium replacement. Which other electrolyte should be checked?
AMagnesium
BChloride
CPhosphate
DSodium
8.Clinical nursingHard
A patient with poorly controlled hyperthyroidism develops a high fever, very fast heart rate, agitation and vomiting during an infection. What is likely?
AHypoglycaemia
BMyxoedema coma
CThyroid storm
DAddisonian crisis
9.Lab values & electrolytesMedium
A patient with chronic kidney disease has a potassium of 5.6 mEq/L. Which food should the nurse advise the patient to limit?
AWhite rice
BBananas
CApples
DCabbage
10.Lab values & electrolytesHard
After lying on the floor for many hours, a patient has a CK of 40,000 U/L, a potassium of 6.1 mEq/L and dark urine. Which prescribed treatment is the priority?
ALarge-volume IV fluids with cardiac monitoring
BAn oral potassium supplement with each meal
CHigh-dose NSAIDs for the muscle pain
DFluid restriction to protect the heart from overload
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 70 mmHg (9.3 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
At sea level, a practice gas taken on 40% oxygen shows PaO₂ 92 mmHg (12.3 kPa) and PaCO₂ 55 mmHg (7.3 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1junctional rhythm
2normal sinus rhythm
3first-degree AV block
4sinus bradycardia
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
22:1 AV block (type undetermined)
3sinus bradycardia
4second-degree AV block type I (Wenckebach)
15.Prioritization & delegationMedium
A pregnant nurse is on the unit. Which patient should the charge nurse avoid assigning to her?
AA patient with type 2 diabetes who needs insulin teaching before discharge
BA patient after a hip replacement
CA patient with a sealed radioactive implant for cervical cancer
DA patient with a fractured wrist
16.Prioritization & delegationHard
Two weeks after birth, a mother says she hears voices telling her the baby is evil. What is the priority?
ALeave her alone with the baby to bond
BAdvise more sleep and book a routine follow-up visit for next month
CKeep the mother and baby safe and arrange urgent psychiatric care
DReassure her that this is normal “baby blues”
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Low potassium and sodium, raised uric acid and raised glucose
Why this is the answer
Thiazides cause hypokalaemia, hyponatraemia, hypomagnesaemia, hyperuricaemia (gout), hyperglycaemia and hypercalcaemia (they reduce calcium excretion). Dry cough and angioedema are ACE inhibitor effects.
Answer
C · Low potassium and sodium, raised uric acid and raised glucose
2.Med-surg: cardiovascular & respiratory
Answer: A · Dullness to percussion on the affected side
Why this is the answer
Blood in the pleural space gives a dull percussion note, whereas air gives hyper-resonance. In haemothorax the neck veins are often flat because of blood loss; in tension pneumothorax they are distended. A massive haemothorax needs a large chest drain, blood replacement and surgical review.
Answer
A · Dullness to percussion on the affected side
3.Med-surg: neuro, endocrine & renal
Answer: A · Use lubricating drops and sleep with the head raised
Why this is the answer
Lubricating drops protect the cornea, raising the head at night reduces swelling, and sunglasses help with light sensitivity. Smoking strongly worsens thyroid eye disease, so stopping is advised.
Answer
A · Use lubricating drops and sleep with the head raised
4.Med-surg: neuro, endocrine & renal
Answer: B · Extensor (decerebrate) posturing: severe brainstem injury
Why this is the answer
Abnormal extension to pain (GCS motor score 2) indicates severe injury at or near the brainstem and carries a worse prognosis than abnormal flexion (decorticate posturing, motor score 3). Any new abnormal posturing needs immediate escalation.
Answer
B · Extensor (decerebrate) posturing: severe brainstem injury
5.Med-surg: GI, perioperative & oncology
Answer: A · Nausea triggered by reminders of treatment before it is given
Why this is the answer
Anticipatory nausea is a conditioned response after previous poorly controlled nausea, triggered by sights or smells linked to treatment. Good antiemetic control from the first cycle helps prevent it; relaxation techniques and anxiolytics may help.
Answer
A · Nausea triggered by reminders of treatment before it is given
6.Med-surg: GI, perioperative & oncology
Answer: D · Phenytoin
Why this is the answer
Enteral feeds bind phenytoin and lower its levels, risking seizures. Feeds are usually paused around doses, as advised by the pharmacist, and drug levels are monitored.
Answer
D · Phenytoin
7.Clinical nursing
Answer: A · Magnesium
Why this is the answer
Hypomagnesaemia increases renal potassium loss and makes hypokalaemia hard to correct. Magnesium must be replaced as well.
Answer
A · Magnesium
8.Clinical nursing
Answer: C · Thyroid storm
Why this is the answer
Thyroid storm is a life-threatening worsening of hyperthyroidism, often triggered by infection or surgery. It needs urgent treatment with cooling, beta-blockade and antithyroid drugs.
Answer
C · Thyroid storm
9.Lab values & electrolytes
Answer: B · Bananas
Why this is the answer
Bananas, oranges, potatoes, tomatoes, dried fruit and beans are high in potassium. Apples, white rice and cabbage are lower-potassium choices that are commonly allowed on a potassium-restricted diet.Checked against:Potassium in diet · MedlinePlus (NIH) (2026); Chronic kidney disease · MedlinePlus (NIH) (2025)
Answer
B · Bananas
10.Lab values & electrolytes
Answer: A · Large-volume IV fluids with cardiac monitoring
Why this is the answer
Rhabdomyolysis releases myoglobin, which can cause acute kidney injury, and potassium, which can cause arrhythmias. Early aggressive IV fluids, a target urine output and cardiac monitoring are priorities. NSAIDs and potassium would worsen kidney injury and hyperkalemia.Checked against:Rhabdomyolysis · MedlinePlus (NIH) (2025)
Answer
A · Large-volume IV fluids with cardiac monitoring
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 34.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|70 − 40| = 30 mmHg → 3 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·3 = 34.5 mmol/L
Answer
HCO₃⁻ = 34.5 mmol/L
12.Arterial blood gas interpretation
Answer: A–a gradient = 124.4 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 29 small boxes, 1500 ÷ 29 ≈ 52 per minute.
2. Rhythm: regular, every R–R is 1.16 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
sinus bradycardia
Answer
sinus bradycardia
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 38 small boxes, 1500 ÷ 38 ≈ 39 per minute.
2. Rhythm: regular, every R–R is 1.52 s.
3. P waves: upright and regular (P–P 0.76 s, 79 per minute), two for every QRS.
4. PR interval: constant at 0.16 s in the conducted beats.
5. QRS: 0.12 s, wide (0.12 s or more).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: C · A patient with a sealed radioactive implant for cervical cancer
Why this is the answer
A sealed radioactive implant (brachytherapy) emits radiation, and pregnant staff should not care for these patients. The other patients pose no special risk to a pregnancy.
Answer
C · A patient with a sealed radioactive implant for cervical cancer
16.Prioritization & delegation
Answer: C · Keep the mother and baby safe and arrange urgent psychiatric care
Why this is the answer
Hallucinations and delusions after birth suggest postpartum psychosis, a psychiatric emergency with risk to mother and baby. Safety and urgent specialist care are the priorities.
Answer
C · Keep the mother and baby safe and arrange urgent psychiatric care