Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
When should an adult with cystic fibrosis take pancreatic enzyme capsules?
AWith all meals and snacks that contain fat
BOnly when they have diarrhoea
COnly at bedtime
DOnce a day on waking, at least an hour before any food
2.Med-surg: cardiovascular & respiratoryHard
A 70-year-old man has a small abdominal aortic aneurysm found on screening and is placed under surveillance. Which advice is most important?
AStop all blood pressure medicines to avoid low pressure
BHave the aneurysm repaired immediately, whatever its size or growth rate
CAvoid all exercise and lifting for the rest of his life to protect the aorta
DStop smoking, control BP and seek help at once for sudden back pain
3.Med-surg: neuro, endocrine & renalMedium
Why can a patient with an insulin pump develop DKA within hours if the pump stops working?
AThe body becomes allergic to insulin when the pump stops
BThe battery in the pump releases chemicals into the blood
CThe pump gives long-acting insulin, which builds up and stops working all at once
DThe pump gives only rapid-acting insulin, so there is no long-acting reserve
4.Med-surg: neuro, endocrine & renalHard
A nurse is caring for four patients. Which patient needs to be seen first?
AA patient after a craniotomy whose right pupil is newly dilated and slow to react
BA patient on peritoneal dialysis with clear effluent
CA patient with CKD asking about their phosphate binder
DA patient with stable hypothyroidism due for levothyroxine
5.Med-surg: GI, perioperative & oncologyMedium
How is the height of an epidural sensory block usually checked?
AMeasuring the patient's blood glucose level
BTesting sensation to cold with ice or a cold spray
CChecking the colour of the patient's urine
DTapping the knee with a reflex hammer and recording the score
6.Med-surg: GI, perioperative & oncologyHard
A patient with diabetes on continuous enteral feeding and an insulin regimen has the feed stopped for a procedure. What is the main concern?
ARefeeding syndrome from too much glucose
BDiarrhoea from stopping the feed suddenly
CHypoglycaemia if insulin continues without the feed
DHyperglycaemia because the stomach is empty
7.Clinical nursingMedium
A patient on insulin reports nightmares, night sweats and morning headaches. What should be suspected?
ARaised intracranial pressure
BNight-time hypoglycaemia
CA urinary tract infection
DHyperthyroidism
8.Clinical nursingHard
A patient going home with a leg cast is taught about cast care. Which statement shows a need for further teaching?
A"I will come back if my toes go numb or turn blue."
B"I will keep the cast dry."
C"I will keep my leg raised on pillows for the first few days."
D"I can push a knitting needle down the cast to scratch an itch."
9.Lab values & electrolytesMedium
Why is a blood β-hydroxybutyrate level often preferred to a urine ketone dipstick in DKA?
AIt measures the main ketone in DKA, and the dipstick may miss it
BIt is the only test that can measure glucose and ketones together
CThe urine dipstick only detects ketones in people without diabetes
DIt shows the average ketone level over the past three months
10.Lab values & electrolytesHard
Why can a normal creatinine be misleading in a frail older adult with low muscle mass?
AOlder adults always have a higher creatinine than younger adults do
BCreatinine levels do not depend on muscle mass at all
CA normal creatinine always proves normal kidney function
DLess muscle makes less creatinine, hiding reduced kidney function
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.61, PaCO₂ 25 mmHg (3.3 kPa) and HCO₃⁻ 24 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.61PaCO₂ 25 mmHg (3.3 kPa)HCO₃⁻ 24 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.24, PaCO₂ 65 mmHg (8.7 kPa), HCO₃⁻ 27 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.24PaCO₂ 65 mmHg (8.7 kPa)HCO₃⁻ 27 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Measure the QT interval on this lead II strip, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QT = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type II
2third-degree (complete) AV block
3sinus bradycardia
42:1 AV block (type undetermined)
15.Prioritization & delegationMedium
A nurse asks a nursing assistant to “assess the patient’s pain and decide if the patient needs more medication”. Which right of delegation is violated?
ARight supervision and evaluation
BRight person
CRight task
DRight circumstance
16.Prioritization & delegationHard
A nurse teaches a patient to inject enoxaparin at home. Which statement shows a need for further teaching?
A“I will rub the area after the injection to help it absorb.”
B“I will tell my doctor if I notice unusual bruising or bleeding.”
C“I will change the injection site each time.”
D“I will inject into the fat of my abdomen, away from the navel.”
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · With all meals and snacks that contain fat
Why this is the answer
In CF, thick secretions block the pancreatic ducts, causing fat malabsorption and fatty stools. Enzyme capsules are taken with every meal and fat-containing snack, with the dose adjusted to fat intake. Fat-soluble vitamins (A, D, E, K) are also supplemented.
Answer
A · With all meals and snacks that contain fat
2.Med-surg: cardiovascular & respiratory
Answer: D · Stop smoking, control BP and seek help at once for sudden back pain
Why this is the answer
Small aneurysms are usually monitored with regular ultrasound, with repair considered when they reach a threshold size or grow fast. Stopping smoking slows growth, and BP and cardiovascular risk are managed. Sudden abdominal or back pain may mean rupture and needs emergency care.
Answer
D · Stop smoking, control BP and seek help at once for sudden back pain
3.Med-surg: neuro, endocrine & renal
Answer: D · The pump gives only rapid-acting insulin, so there is no long-acting reserve
Why this is the answer
Insulin pumps deliver a continuous flow of rapid-acting insulin. If delivery stops, there is no depot of long-acting insulin, so ketones can rise within a few hours. Patients carry pens or syringes as a backup.
Answer
D · The pump gives only rapid-acting insulin, so there is no long-acting reserve
4.Med-surg: neuro, endocrine & renal
Answer: A · A patient after a craniotomy whose right pupil is newly dilated and slow to react
Why this is the answer
A new, one-sided dilated and sluggish pupil after brain surgery suggests rising intracranial pressure pressing on the oculomotor nerve, a possible sign of brain herniation. It needs immediate assessment, including the GCS and vital signs, and urgent escalation. The other patients are stable, and their needs can be met shortly afterwards.
Answer
A · A patient after a craniotomy whose right pupil is newly dilated and slow to react
5.Med-surg: GI, perioperative & oncology
Answer: B · Testing sensation to cold with ice or a cold spray
Why this is the answer
The level at which the patient no longer feels cold shows the upper extent of the sensory block. Motor block is assessed with a scale such as Bromage. A rising block or new weakness is reported.
Answer
B · Testing sensation to cold with ice or a cold spray
6.Med-surg: GI, perioperative & oncology
Answer: C · Hypoglycaemia if insulin continues without the feed
Why this is the answer
When feed stops but insulin continues, blood glucose can fall sharply. The insulin plan is reviewed with the team, glucose is checked frequently, and a glucose infusion may be needed.
Answer
C · Hypoglycaemia if insulin continues without the feed
7.Clinical nursing
Answer: B · Night-time hypoglycaemia
Why this is the answer
Nocturnal hypoglycaemia can cause sweating, restless sleep, nightmares and morning headache. Checking glucose overnight and reviewing insulin doses can confirm and correct it.
Answer
B · Night-time hypoglycaemia
8.Clinical nursing
Answer: D · "I can push a knitting needle down the cast to scratch an itch."
Why this is the answer
Pushing objects under a cast can injure the skin and cause infection or pressure sores. Elevation, keeping the cast dry and reporting numbness, colour change or increasing pain are correct.
Answer
D · "I can push a knitting needle down the cast to scratch an itch."
9.Lab values & electrolytes
Answer: A · It measures the main ketone in DKA, and the dipstick may miss it
Why this is the answer
In DKA, β-hydroxybutyrate is the main ketone, but most urine dipsticks detect acetoacetate, so they can underestimate ketosis. Blood β-hydroxybutyrate gives a current value that is also useful to monitor recovery.Checked against:Diabetic ketoacidosis - Medical Encyclopedia · MedlinePlus (NIH) (2025)
Answer
A · It measures the main ketone in DKA, and the dipstick may miss it
10.Lab values & electrolytes
Answer: D · Less muscle makes less creatinine, hiding reduced kidney function
Why this is the answer
Creatinine is made by muscle. A person with little muscle makes little creatinine, so the value can look normal even when kidney function is reduced. Creatinine-based eGFR can overestimate function in the same way, so a measured creatinine clearance or a cystatin C–based estimate may be used when dosing drugs cleared by the kidneys.Checked against:Creatinine blood test · MedlinePlus (NIH) (2025)
Answer
D · Less muscle makes less creatinine, hiding reduced kidney function
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.61: alkalaemia (above 7.45)
PaCO₂ 25 mmHg: low (35–45)
HCO₃⁻ 24 mmol/L: normal (22–26)
Compensation
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·2.5 = 26.5 mmol/L
chronic: 24 + 3.5·2.5 = 32.75 mmol/L
Compare
measured: 27 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: QT = 0.48 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
12 small boxes from the start of the QRS to the end of the T wave
Convert
QT = 12 × 0.04 s = 0.48 s
Answer
QT = 0.48 s
A rough rule: at normal rates the QT should be less than half the R–R interval (here R–R = 0.88 s).
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 44 small boxes, 1500 ÷ 44 ≈ 34 per minute.
2. Rhythm: regular, every R–R is 1.76 s.
3. P waves: upright and regular (P–P 0.88 s, 68 per minute), two for every QRS.
4. PR interval: constant at 0.18 s in the conducted beats.
5. QRS: 0.06 s, narrow (below 0.12 s).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: C · Right task
Why this is the answer
Assessing a patient and deciding on treatment need nursing judgement, so the task itself cannot be delegated to assistive personnel. An assistant can report what the patient says, but the RN assesses and decides.
Answer
C · Right task
16.Prioritization & delegation
Answer: A · “I will rub the area after the injection to help it absorb.”
Why this is the answer
Rubbing the site after a low-molecular-weight heparin injection increases bruising. The abdomen away from the navel, rotating sites and reporting bleeding are correct.
Answer
A · “I will rub the area after the injection to help it absorb.”