Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
During an episode of chest pain, a patient's ECG shows new horizontal ST depression. What does this most likely indicate?
AMyocardial ischaemia
BPericarditis
CHyperkalaemia
DA normal finding during pain
2.Med-surg: cardiovascular & respiratoryHard
A 74-year-old with atrial fibrillation, hypertension and diabetes asks why she needs an anticoagulant when she feels well. Which reply is best?
AIt is needed only while she has palpitations
BIt is given to lower her blood pressure
CHer risk of stroke is high, and an anticoagulant lowers it
DThe anticoagulant will stop the irregular heartbeat for good
3.Med-surg: neuro, endocrine & renalMedium
Which CSF result is most typical of bacterial meningitis?
ACloudy fluid, many neutrophils, low glucose and high protein
BClear fluid with normal cells, glucose and protein
CBlood-stained fluid that clears in later tubes
DClear fluid, many lymphocytes, normal glucose and slightly raised protein
4.Med-surg: neuro, endocrine & renalHard
Six weeks after a kidney transplant, a patient has a fever, tenderness over the graft, less urine and a rising creatinine. What is most likely?
AAcute rejection, needing urgent transplant team review
BA side effect of sun exposure
CA normal finding as the kidney settles in
DDehydration that needs only more oral fluids and rest
5.Med-surg: GI, perioperative & oncologyMedium
Which advice may help reduce the risk of a parastomal hernia after stoma surgery?
AStrain hard on the toilet each day to strengthen the abdominal muscles
BKeep the stoma bag as full as possible
CDo intensive sit-ups from the first week
DAvoid heavy lifting early on and use support garments as advised
6.Med-surg: GI, perioperative & oncologyHard
A patient with a sacral pressure ulcer keeps sliding down the bed when the head is raised high. Which advice best reduces shear?
ASit the patient upright without any support for the feet
BKeep the head of the bed at or below 30° if possible; use slide sheets
CRaise the head of the bed to 90° and pull the patient up the bed by the arms
DUse a dry sheet and drag the patient up the bed
7.Clinical nursingMedium
When a patient returns to the ward from theatre, what should the nurse assess first?
AThe patient's dietary preferences for the next meal
BWhether visitors are waiting to see the patient
CAirway, breathing, circulation and level of consciousness
DThe discharge date
8.Clinical nursingHard
A patient with lung cancer develops swelling of the face and arms, distended neck veins and breathlessness that is worse lying down. What should be suspected?
AAn allergic reaction to food
BSuperior vena cava obstruction
CRight-sided heart failure from valve disease
DHypothyroidism
9.Lab values & electrolytesMedium
On the first day after major surgery, a patient's white cell count is 12.5 × 10³/µL, with no fever or wound signs. What is the best interpretation?
AA laboratory error, since surgery lowers white cells
BDefinite wound infection that needs antibiotics now
CA sign of leukemia that needs bone marrow testing
DA common stress response to surgery that is monitored
10.Lab values & electrolytesHard
A patient has sudden episodes of severe headache, sweating, palpitations and very high blood pressure. Which test is most useful to look for the cause?
APlasma free metanephrines
BSerum calcium only
CSerum TSH and free T4
DFasting lipid profile
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 151 mmol/L, glucose 23.6 mmol/L and urea 24.4 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 151 mmol/Lglucose 23.6 mmol/Lurea 24.4 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 50% oxygen shows PaO₂ 91 mmHg (12.1 kPa) and PaCO₂ 49 mmHg (6.5 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1normal sinus rhythm
2sinus arrhythmia
3atrial fibrillation
4ventricular bigeminy
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2idioventricular rhythm
3junctional rhythm
4paced rhythm, failure to capture
15.Prioritization & delegationMedium
When making patient assignments, what should the charge nurse consider first?
ALetting staff choose the patients they prefer
BGiving the newest staff the most complex patients
CMatching each patient’s needs to staff competence
DGiving each nurse patients in rooms next to each other
16.Prioritization & delegationHard
During START triage, an adult is not breathing. The airway is repositioned and the victim still does not breathe. What is the correct category?
ARed, and start CPR at once
BYellow, and come back later
CRed, because no breathing is the most urgent finding
DBlack (deceased or expectant)
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Myocardial ischaemia
Why this is the answer
New horizontal or downsloping ST depression during pain suggests myocardial ischaemia, as in unstable angina or NSTEMI. It should be reported immediately with serial ECGs and troponins. ST depression can also reflect reciprocal change opposite a STEMI.
Answer
A · Myocardial ischaemia
2.Med-surg: cardiovascular & respiratory
Answer: C · Her risk of stroke is high, and an anticoagulant lowers it
Why this is the answer
In AF, blood stasis in the left atrium causes clots that can travel to the brain. Scores such as CHA₂DS₂-VASc (age, hypertension, diabetes, female sex and others) estimate stroke risk; her score is high. Anticoagulation reduces stroke risk but does not change the rhythm.
Answer
C · Her risk of stroke is high, and an anticoagulant lowers it
3.Med-surg: neuro, endocrine & renal
Answer: A · Cloudy fluid, many neutrophils, low glucose and high protein
Why this is the answer
Bacterial meningitis usually gives turbid CSF with raised neutrophils and protein and low glucose. Viral meningitis typically shows clear fluid with lymphocytes and normal glucose.
Answer
A · Cloudy fluid, many neutrophils, low glucose and high protein
4.Med-surg: neuro, endocrine & renal
Answer: A · Acute rejection, needing urgent transplant team review
Why this is the answer
Fever, graft tenderness, falling urine output and rising creatinine suggest acute rejection, although infection must also be ruled out. Early treatment, often with high-dose steroids, can save the graft, so the transplant team is contacted urgently.
Answer
A · Acute rejection, needing urgent transplant team review
5.Med-surg: GI, perioperative & oncology
Answer: D · Avoid heavy lifting early on and use support garments as advised
Why this is the answer
Avoiding heavy lifting in the early months, supporting the abdomen when coughing, gentle core exercises as advised by the stoma team and a healthy weight may reduce risk.
Answer
D · Avoid heavy lifting early on and use support garments as advised
6.Med-surg: GI, perioperative & oncology
Answer: B · Keep the head of the bed at or below 30° if possible; use slide sheets
Why this is the answer
A high head position makes patients slide, causing shear on the sacrum. A lower head position when clinically possible, knee break or foot support, and slide sheets for moving reduce shear and friction.
Answer
B · Keep the head of the bed at or below 30° if possible; use slide sheets
7.Clinical nursing
Answer: C · Airway, breathing, circulation and level of consciousness
Why this is the answer
Early postoperative assessment checks the airway, breathing, oxygen saturation, circulation, consciousness, pain, wound and drains. This detects anaesthetic and surgical complications early.
Answer
C · Airway, breathing, circulation and level of consciousness
8.Clinical nursing
Answer: B · Superior vena cava obstruction
Why this is the answer
Superior vena cava obstruction prevents venous drainage from the head and arms. It is an oncological emergency; patients are positioned upright and need urgent specialist treatment.
Answer
B · Superior vena cava obstruction
9.Lab values & electrolytes
Answer: D · A common stress response to surgery that is monitored
Why this is the answer
A mild leukocytosis is common after surgery because of tissue injury and the stress response. It is monitored along with temperature and wound assessment. A rising count after several days, or fever, suggests infection.Checked against:WBC count · MedlinePlus (NIH) (2025)
Answer
D · A common stress response to surgery that is monitored
10.Lab values & electrolytes
Answer: A · Plasma free metanephrines
Why this is the answer
These episodes suggest pheochromocytoma, a tumor of the adrenal medulla that releases catecholamines. Plasma free metanephrines (or 24-hour urine metanephrines) are the main screening tests. Hyperthyroidism can cause similar symptoms but usually without these bursts of severe hypertension.Checked against:Pheochromocytoma · MedlinePlus (NIH) (2024)
Answer
A · Plasma free metanephrines
11.Arterial blood gas interpretation
Answer: Osm = 350 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·151 + 23.6 + 24.4 = 350 ≈ 350 mOsm/kg
Answer
Osm = 350 mOsm/kg
12.Arterial blood gas interpretation
Answer: A–a gradient = 204.3 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 7 QRS complexes in 6 s, × 10 = 70 per minute.
2. Rhythm: regularly irregular, a short and a long R–R alternate (0.46 s and 1.22 s).
3. P waves: upright before every narrow QRS; none before the early wide beats.
4. PR interval: 0.18 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s in the sinus beats; the early beats are wide (0.14 s) and bizarre, with the T wave pointing the other way.
Interpretation
ventricular bigeminy
Answer
ventricular bigeminy
14.ECG rhythm strip interpretation
Answer: dual-chamber (AV) paced rhythm
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: R–R = 24 small boxes, 1500 ÷ 24 ≈ 63 per minute.
2. Rhythm: regular, every R–R is 0.96 s.
3. P waves: each P wave follows its own pacing spike (atrial pacing).
4. AV interval: the second spike comes 0.18 s after the first one (the programmed AV delay).
5. QRS: 0.14 s, wide, right after the second spike (ventricular pacing).
Interpretation
dual-chamber (AV) paced rhythm
Answer
dual-chamber (AV) paced rhythm
The paced QRS is wide by nature; do not call it a bundle branch block or a ventricular rhythm.
15.Prioritization & delegation
Answer: C · Matching each patient’s needs to staff competence
Why this is the answer
Assignments are based mainly on patient acuity and needs and on each staff member’s skills and scope. Geography and continuity of care help, but they come after safety.
Answer
C · Matching each patient’s needs to staff competence
16.Prioritization & delegation
Answer: D · Black (deceased or expectant)
Why this is the answer
In START, a victim who does not breathe after the airway is repositioned is tagged black. CPR for one person would take rescuers away from many others who could survive. If breathing starts after repositioning, the victim is red.