Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
According to current guidance, when should oxygen be given to a patient with an acute coronary syndrome?
AAlways at 15 L/min, whatever the saturation
BOnly when SpO₂ is below the target range
CNever, because oxygen harms heart muscle
DOnly once the troponin result is available
2.Med-surg: cardiovascular & respiratoryHard
A nurse teaches a patient how to measure blood pressure at home. Which statement shows a need for further teaching?
A"I will take two readings and write them both down."
B"I will sit with my back supported and my arm at heart level."
C"I will measure it straight after my morning jog."
D"I will rest quietly for five minutes before measuring."
3.Med-surg: neuro, endocrine & renalMedium
Why can a patient with an insulin pump develop DKA within hours if the pump stops working?
AThe body becomes allergic to insulin when the pump stops
BThe battery in the pump releases chemicals into the blood
CThe pump gives long-acting insulin, which builds up and stops working all at once
DThe pump gives only rapid-acting insulin, so there is no long-acting reserve
4.Med-surg: neuro, endocrine & renalHard
A patient taking lithium has polyuria and thirst, and the urine does not concentrate after desmopressin. What is the most likely cause?
ACranial DI after a head injury
BNewly developed type 1 diabetes
CNephrogenic DI caused by lithium
DSIADH caused by lithium
5.Med-surg: GI, perioperative & oncologyMedium
A patient with cirrhosis takes lactulose for hepatic encephalopathy. What is the usual aim?
AOne firm stool every week
BNo bowel movement for several days
CTen or more watery stools a day
DTwo to three soft stools a day
6.Med-surg: GI, perioperative & oncologyHard
A patient on chemotherapy has white plaques on the tongue and cheeks that wipe off to leave red areas. What is most likely?
AOral candidiasis
BNormal mucositis healing
CFood residue only
DLeukoplakia from smoking
7.Clinical nursingMedium
Which is the correct technique for using a metered-dose inhaler without a spacer?
ABreathe out, then breathe in slowly and deeply while pressing the canister, then hold
BPress the canister and wait one minute before breathing in
CPress the canister twice quickly, then breathe in fast and breathe straight out again
DBreathe in quickly through the nose while pressing the canister
8.Clinical nursingHard
A patient with a small leg wound has severe pain out of proportion to the skin changes, rapidly spreading redness and signs of sepsis. What should be suspected?
AAn allergic reaction to the dressing
BSimple cellulitis that will settle with oral antibiotics
CNecrotising fasciitis
DA superficial bruise
9.Lab values & electrolytesMedium
A patient taking phenazopyridine for bladder pain has bright orange urine. What should the nurse know about urine tests?
AThe color shows severe liver failure is present
BThe dye can interfere with dipstick color readings
CThe color proves blood is present in the urine
DThe drug improves the accuracy of all dipsticks
10.Lab values & electrolytesHard
A patient has fatigue, weight loss, darkening of the skin and low blood pressure. Results: sodium 130 mEq/L, potassium 5.6 mEq/L. Which test pattern would confirm primary adrenal insufficiency (Addison disease)?
ALow cortisol with a high ACTH
BHigh cortisol with a high ACTH
CLow cortisol with a low ACTH
DHigh cortisol with a low ACTH
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 62 mmHg (8.3 kPa). Use the rule that in acute respiratory acidosis HCO₃⁻ rises by 1 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic acidosis: pH 7.33, PaCO₂ 35 mmHg (4.7 kPa), HCO₃⁻ 18 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.33PaCO₂ 35 mmHg (4.7 kPa)HCO₃⁻ 18 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2sinus rhythm with PVCs
3first-degree AV block
4ventricular bigeminy
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2asystole
3third-degree (complete) AV block
4junctional rhythm
15.Prioritization & delegationMedium
Which patient is most appropriate to assign to an LPN/LVN?
AA patient about to receive a first unit of red blood cells
BA patient with stable chronic heart failure who needs oral medications
CA patient arriving from the recovery room who needs an initial assessment
DA patient admitted 30 minutes ago with new chest pain
16.Prioritization & delegationHard
In an emergency department, which patient should go straight to a treatment room?
AA 30-year-old with a sore throat for two days and a temperature of 38.0 °C
BA 45-year-old asking for a repeat prescription
CA 60-year-old with chest pressure, sweating and nausea for 20 minutes
DA 25-year-old with a sprained wrist and normal vital signs
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Only when SpO₂ is below the target range
Why this is the answer
Routine high-flow oxygen in patients who are not hypoxaemic offers no benefit and may increase infarct size. Oxygen is given when saturation falls below the target (for example below 90% in some guidelines, below 94% in others).
Answer
B · Only when SpO₂ is below the target range
2.Med-surg: cardiovascular & respiratory
Answer: C · "I will measure it straight after my morning jog."
Why this is the answer
Home readings should be taken after resting quietly for about 5 minutes, sitting with back supported, feet flat and the arm supported at heart level, with no recent exercise, caffeine or smoking. Two readings are often recorded. Measuring after exercise gives falsely high results.
Answer
C · "I will measure it straight after my morning jog."
3.Med-surg: neuro, endocrine & renal
Answer: D · The pump gives only rapid-acting insulin, so there is no long-acting reserve
Why this is the answer
Insulin pumps deliver a continuous flow of rapid-acting insulin. If delivery stops, there is no depot of long-acting insulin, so ketones can rise within a few hours. Patients carry pens or syringes as a backup.
Answer
D · The pump gives only rapid-acting insulin, so there is no long-acting reserve
4.Med-surg: neuro, endocrine & renal
Answer: C · Nephrogenic DI caused by lithium
Why this is the answer
Lithium is a common cause of nephrogenic DI, in which the collecting ducts do not respond to ADH, so desmopressin has little effect. Management includes specialist review of the lithium, access to water and monitoring of sodium and lithium levels.
Answer
C · Nephrogenic DI caused by lithium
5.Med-surg: GI, perioperative & oncology
Answer: D · Two to three soft stools a day
Why this is the answer
Lactulose acidifies the colon and traps ammonia, and it speeds transit. The dose is titrated to 2–3 soft stools a day. Excessive diarrhoea can cause dehydration and electrolyte disturbance that worsen encephalopathy.
Answer
D · Two to three soft stools a day
6.Med-surg: GI, perioperative & oncology
Answer: A · Oral candidiasis
Why this is the answer
Oral thrush is common during chemotherapy, especially with steroids or antibiotics. It is reported so that antifungal treatment can be prescribed, and good oral care continues.
Answer
A · Oral candidiasis
7.Clinical nursing
Answer: A · Breathe out, then breathe in slowly and deeply while pressing the canister, then hold
Why this is the answer
The patient breathes out, seals the lips around the mouthpiece, starts breathing in slowly, presses the canister and continues a deep breath, then holds it for about 10 seconds. Spacers make coordination easier.
Answer
A · Breathe out, then breathe in slowly and deeply while pressing the canister, then hold
8.Clinical nursing
Answer: C · Necrotising fasciitis
Why this is the answer
Necrotising fasciitis spreads rapidly along fascia; severe pain, systemic toxicity and fast progression are key warning signs. It is a surgical emergency needing urgent debridement and IV antibiotics.
Answer
C · Necrotising fasciitis
9.Lab values & electrolytes
Answer: B · The dye can interfere with dipstick color readings
Why this is the answer
Phenazopyridine is a urinary analgesic dye that turns urine orange-red. It can interfere with color-based dipstick tests, so the laboratory should be told. The color is harmless, but it can stain contact lenses and clothing.Checked against:Urine - abnormal color · MedlinePlus (NIH) (2025)
Answer
B · The dye can interfere with dipstick color readings
10.Lab values & electrolytes
Answer: A · Low cortisol with a high ACTH
Why this is the answer
In primary adrenal insufficiency the adrenal glands fail, so cortisol is low and the pituitary responds with high ACTH, which also darkens the skin. Low cortisol with low ACTH suggests a pituitary cause. An ACTH stimulation test confirms the diagnosis.Checked against:Adrenocorticotropic Hormone (ACTH) · MedlinePlus (NIH) (2023); Cortisol Test · MedlinePlus (NIH) (2024)
Answer
A · Low cortisol with a high ACTH
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 26.2 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|62 − 40| = 22 mmHg → 2.2 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 1·2.2 = 26.2 mmol/L
Answer
HCO₃⁻ = 26.2 mmol/L
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·18 + 8 = 35 → 33–37 mmHg
Compare
measured: 35 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: sinus rhythm with PVCs
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 6 QRS complexes in 6 s, × 10 = 60 per minute.
2. Rhythm: regular (0.92 s) except for the early beats and the pause after each of them.
3. P waves: upright before every narrow QRS; none before the early wide beats.
4. PR interval: 0.16 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s in the sinus beats; the early beats are wide (0.14 s) and bizarre, with the T wave pointing the other way.
Interpretation
sinus rhythm with PVCs
Answer
sinus rhythm with PVCs
14.ECG rhythm strip interpretation
Answer: asystole
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: none; an almost flat line.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
asystole
Answer
asystole
A flat line is always checked: look at the patient, the leads and the gain, and view a second lead, because a loose electrode or fine VF can look like asystole.
15.Prioritization & delegation
Answer: B · A patient with stable chronic heart failure who needs oral medications
Why this is the answer
Stable chronic heart failure with routine oral medicines is predictable care. New chest pain, the start of a transfusion and the first assessment after surgery need RN assessment.
Answer
B · A patient with stable chronic heart failure who needs oral medications
16.Prioritization & delegation
Answer: C · A 60-year-old with chest pressure, sweating and nausea for 20 minutes
Why this is the answer
Chest pressure with sweating and nausea may be a heart attack, so the patient needs an ECG within minutes. The other patients are stable and can safely wait.
Answer
C · A 60-year-old with chest pressure, sweating and nausea for 20 minutes