Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with supraventricular tachycardia is to receive IV adenosine. What should the nurse warn them about?
ASeveral hours of drowsiness, slurred speech and confusion afterwards
BA burning pain along the arm vein for about a week
CBrief flushing or chest tightness and a pause of a few seconds
DA headache that lasts for several days afterwards
2.Med-surg: cardiovascular & respiratoryHard
An older patient's varicose vein bursts at the ankle and bleeds heavily. What is the most effective first aid?
AStand the patient up so the blood flows away and clots faster
BLie the patient down, raise the leg and press firmly on the site
CApply a hot compress to the leg to help the vein close up
DKeep the leg hanging down over the bed
3.Med-surg: neuro, endocrine & renalMedium
For which patient would the nurse question an order for pioglitazone?
AA patient with asthma
BA patient with hypothyroidism
CA patient with an allergy to latex
DA patient with heart failure
4.Med-surg: neuro, endocrine & renalHard
On day 6 after a subarachnoid haemorrhage, a patient becomes newly confused and develops weakness in one arm. The aneurysm was secured on day 1. What is the most likely cause?
AHypoglycaemia from reduced eating
BNormal tiredness after major surgery
CDelayed cerebral ischaemia from vasospasm
DRe-bleeding from the secured aneurysm
5.Med-surg: GI, perioperative & oncologyMedium
How should a patient with facial burns usually be positioned?
ALying flat with the head lower than the feet
BWith the head of the bed raised to reduce swelling
CIn any position that keeps the face covered
DLying face down on the pillow to protect the airway
6.Med-surg: GI, perioperative & oncologyHard
A nurse teaches a patient after a colonoscopy with polyp removal. Which statement shows a need for further teaching?
A"Some wind and bloating today is expected."
B"I'll report heavy bleeding from my bottom."
C"Severe abdominal pain is normal for a week afterwards."
D"I should report a fever or a swollen, painful abdomen."
7.Clinical nursingMedium
Long-term amiodarone treatment can affect which of the following?
AHair colour and nail growth only, with no effect on organs
BBlood glucose and cholesterol only
CThe sense of smell and taste only, with no other effects
DThyroid function, the lungs and the skin's sensitivity to sunlight
8.Clinical nursingHard
Why must a unit of red cells be transfused within the set time limit (commonly four hours) after it leaves controlled cold storage?
AThe bag stops dripping after four hours
BBacteria can grow in the blood at room temperature
CThe red cells break down and turn into plasma
DThe blood group of the cells changes after a few hours
9.Lab values & electrolytesMedium
A patient with sickle cell disease takes hydroxyurea. Which laboratory test is monitored regularly for an adverse effect?
ASerum amylase level
BSerum lithium level
CComplete blood count
DUrine ketone level
10.Lab values & electrolytesHard
A patient's low calcium does not improve despite several days of calcium replacement. Which other electrolyte should be checked and corrected?
AMagnesium
BBicarbonate
CSodium
DChloride
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.59, PaCO₂ 39 mmHg (5.2 kPa) and HCO₃⁻ 36 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.59PaCO₂ 39 mmHg (5.2 kPa)HCO₃⁻ 36 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.31, PaCO₂ 33 mmHg (4.4 kPa), HCO₃⁻ 16 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.31PaCO₂ 33 mmHg (4.4 kPa)HCO₃⁻ 16 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2third-degree (complete) AV block
32:1 AV block (type undetermined)
4sinus bradycardia
15.Prioritization & delegationMedium
A nurse sees a nursing assistant leave a confused patient’s bed in the highest position after care. What should the nurse do?
AWrite it in the assistant’s yearly review only
BLeave it because the patient is asleep
CAsk the family to lower the bed when they next visit
DLower the bed now and remind the assistant why it matters
16.Prioritization & delegationHard
A patient rescued from a house fire has burns to the face, singed nasal hair and a hoarse voice. What is the priority?
ACleaning and dressing the facial burns
BStarting IV fluid resuscitation calculated from the burn size
CProtecting the airway, preparing for early airway support
DGiving pain relief
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Brief flushing or chest tightness and a pause of a few seconds
Why this is the answer
Adenosine is given as a rapid IV bolus followed by a saline flush, with continuous ECG monitoring. It briefly blocks AV node conduction, often causing a few seconds of asystole, flushing, chest discomfort, breathlessness or a sense of doom. The effects last only seconds.
Answer
C · Brief flushing or chest tightness and a pause of a few seconds
2.Med-surg: cardiovascular & respiratory
Answer: B · Lie the patient down, raise the leg and press firmly on the site
Why this is the answer
Bleeding from a varicose vein can be dramatic. Lying the patient flat and raising the leg above heart level lowers venous pressure, and firm direct pressure stops most bleeds. Medical review is needed afterwards, as it can recur.
Answer
B · Lie the patient down, raise the leg and press firmly on the site
3.Med-surg: neuro, endocrine & renal
Answer: D · A patient with heart failure
Why this is the answer
Pioglitazone can cause fluid retention and oedema, which can worsen heart failure. It is contraindicated in patients with heart failure. Weight gain and an increased fracture risk are other effects.
Answer
D · A patient with heart failure
4.Med-surg: neuro, endocrine & renal
Answer: C · Delayed cerebral ischaemia from vasospasm
Why this is the answer
Vasospasm of cerebral arteries typically occurs several days after a subarachnoid haemorrhage and causes new focal deficits or confusion. It needs urgent medical review. Normal fluid balance is maintained, and nimodipine is continued.
Answer
C · Delayed cerebral ischaemia from vasospasm
5.Med-surg: GI, perioperative & oncology
Answer: B · With the head of the bed raised to reduce swelling
Why this is the answer
Raising the head reduces facial and airway swelling. The airway is monitored closely because swelling can increase over the first 24–48 hours.
Answer
B · With the head of the bed raised to reduce swelling
6.Med-surg: GI, perioperative & oncology
Answer: C · "Severe abdominal pain is normal for a week afterwards."
Why this is the answer
Mild bloating and cramps from the air used are expected. Severe or worsening pain, fever, a distended abdomen or heavy rectal bleeding can mean perforation or haemorrhage and must be reported straight away.
Answer
C · "Severe abdominal pain is normal for a week afterwards."
7.Clinical nursing
Answer: D · Thyroid function, the lungs and the skin's sensitivity to sunlight
Why this is the answer
Amiodarone can cause hypo- or hyperthyroidism, pulmonary fibrosis, liver problems and photosensitivity. Regular monitoring of thyroid and liver function is needed.
Answer
D · Thyroid function, the lungs and the skin's sensitivity to sunlight
8.Clinical nursing
Answer: B · Bacteria can grow in the blood at room temperature
Why this is the answer
Red cells are stored cold to limit bacterial growth. Once out of controlled storage, the transfusion must be completed within the time limit to reduce the risk of bacterial contamination and transfusion-transmitted infection.
Answer
B · Bacteria can grow in the blood at room temperature
9.Lab values & electrolytes
Answer: C · Complete blood count
Why this is the answer
Hydroxyurea increases fetal hemoglobin and reduces sickling crises, but it can suppress the bone marrow. The CBC, including neutrophils and platelets, is monitored regularly, and doses are adjusted if counts fall.Checked against:Sickle cell disease · MedlinePlus (NIH) (2026)
Answer
C · Complete blood count
10.Lab values & electrolytes
Answer: A · Magnesium
Why this is the answer
Low magnesium reduces parathyroid hormone secretion and the body's response to it, so hypocalcemia does not correct until magnesium is replaced. The same applies to refractory hypokalemia.Checked against:Magnesium Blood Test · MedlinePlus (NIH) (2023)
Answer
A · Magnesium
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.59: alkalaemia (above 7.45)
PaCO₂ 39 mmHg: normal (35–45)
HCO₃⁻ 36 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 44.2–48.2 mmHg, so the measured 39 mmHg points to an additional respiratory alkalosis (a mixed disorder). The answer above is the ROME exam classification.
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·16 + 8 = 32 → 30–34 mmHg
Compare
measured: 33 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: QTc = 0.435 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 11.5 × 0.04 = 0.46 s
RR = 28 × 0.04 = 1.12 s
Bazett’s formula
QTc = 0.46/√1.12 = 0.46/1.058 = 0.435 s
Answer
QTc = 0.435 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (435 ms)
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 36 small boxes, 1500 ÷ 36 ≈ 42 per minute.
2. Rhythm: regular, every R–R is 1.44 s.
3. P waves: upright and regular (P–P 0.72 s, 83 per minute), two for every QRS.
4. PR interval: constant at 0.16 s in the conducted beats.
5. QRS: 0.06 s, narrow (below 0.12 s).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: D · Lower the bed now and remind the assistant why it matters
Why this is the answer
A high bed increases the risk of a serious fall, so the nurse corrects it at once and gives brief, clear feedback. Leaving it or delaying feedback leaves the patient at risk.
Answer
D · Lower the bed now and remind the assistant why it matters
16.Prioritization & delegation
Answer: C · Protecting the airway, preparing for early airway support
Why this is the answer
Singed nasal hair and hoarseness suggest inhalation injury. The upper airway can swell and close within hours, so it is protected early. Fluids, pain relief and wound care follow.
Answer
C · Protecting the airway, preparing for early airway support