Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has had atrial fibrillation for more than 48 hours and is listed for elective cardioversion. Why is anticoagulation needed beforehand?
AAtrial clots may be dislodged when sinus rhythm returns
BAnticoagulants reduce the electrical energy needed for the shock
CAnticoagulants convert AF back to sinus rhythm
DAnticoagulants make the shock less painful
2.Med-surg: cardiovascular & respiratoryHard
A patient had 40 minutes of chest pain at rest. The ECG shows ST depression without ST elevation, and the troponin is rising. What is the diagnosis?
AST-elevation myocardial infarction (STEMI)
BStable angina
CNon-ST-elevation myocardial infarction
DAcute pericarditis
3.Med-surg: neuro, endocrine & renalMedium
Why might a patient bleed more from the needle sites straight after haemodialysis?
AThe fistula has been damaged and must be tied off
BHeparin is often used to stop the circuit from clotting
CDialysis raises the blood pressure sharply for several hours
DDialysis removes all the platelets from the blood
4.Med-surg: neuro, endocrine & renalHard
The nurse has four patients. Which one needs to be seen first?
AA patient with Parkinson's disease whose next dose is due in two hours
BA patient on insulin for DKA whose potassium is now 2.9 mmol/L
CA patient with hypothyroidism asking when to take levothyroxine
DA patient with stable CKD waiting for a renal diet review
5.Med-surg: GI, perioperative & oncologyMedium
Which nerve is at risk if the arm is poorly padded at the elbow during surgery?
AFemoral nerve
BFacial nerve
CSciatic nerve
DUlnar nerve
6.Med-surg: GI, perioperative & oncologyHard
A nurse spills a small amount of a cytotoxic drug on the floor. What is the correct approach?
AUse the spill kit with PPE, clean up, bag as cytotoxic waste and report
BLeave it to evaporate and keep people away for a few minutes
CWipe it with a paper towel and put it in the general waste bin
DMop it up with the ward mop and rinse the mop in the sluice
7.Clinical nursingMedium
A patient with pneumonia is breathless and coughing up thick sputum. Which nursing measure helps most with breathing?
ADiscouraging coughing to save energy
BRestricting all oral fluids
CSitting the patient upright and supporting them to clear secretions
DLying the patient flat so that they can rest and conserve energy
8.Clinical nursingHard
Which patient should a ward nurse assess first at the start of a shift?
AA patient with chronic back pain scored 4/10
BA patient with new-onset confusion and a respiratory rate of 28/min
CA patient asking for a laxative
DA patient awaiting discharge with stable observations
9.Lab values & electrolytesMedium
A patient has a sodium of 124 mEq/L, a headache and new confusion. Which nursing measure is most appropriate?
APut seizure precautions in place and monitor neurological status
BGive the next dose of the prescribed thiazide diuretic early
CEncourage the patient to drink plenty of plain water
DKeep the patient flat and limit neurological checks to once a shift
10.Lab values & electrolytesHard
A patient has marked generalized edema. Results show heavy proteinuria, serum albumin 1.8 g/dL (18 g/L) and total cholesterol 340 mg/dL (8.8 mmol/L). Which condition fits best?
ALiver cirrhosis only
BAcute pyelonephritis
CNephrotic syndrome
DPrerenal kidney injury
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.24, PaCO₂ 24 mmHg (3.2 kPa) and HCO₃⁻ 10 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.24PaCO₂ 24 mmHg (3.2 kPa)HCO₃⁻ 10 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.23, PaCO₂ 22 mmHg (2.9 kPa), HCO₃⁻ 9 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.23PaCO₂ 22 mmHg (2.9 kPa)HCO₃⁻ 9 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type I (Wenckebach)
2third-degree (complete) AV block
3junctional rhythm
4second-degree AV block type II
15.Prioritization & delegationMedium
After handover, which patient should the nurse see first?
AA patient with pneumonia, temperature 38.2 °C, who had an antipyretic 30 minutes ago
BA patient with diabetes whose glucose before breakfast is 160 mg/dL (8.9 mmol/L)
CA patient two days after hip replacement with pain of 5/10
DA patient with asthma who is using accessory muscles and has an SpO₂ of 88%
16.Prioritization & delegationHard
A patient with diabetes is sweaty and confused, and no glucose meter is available. The patient can swallow. What should the nurse do?
ATreat for hypoglycemia with fast-acting oral carbohydrate
BAsk the patient to lie down and sleep it off
CGive a dose of rapid-acting insulin in case the glucose is high
DWithhold all food and fluids until a meter is found
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Atrial clots may be dislodged when sinus rhythm returns
Why this is the answer
After 48 hours of AF, atrial thrombus may be present. Restoring organised contraction can expel it and cause a stroke. Patients are usually anticoagulated for at least three weeks before (or a transoesophageal echo excludes clot) and for at least four weeks afterwards.
Answer
A · Atrial clots may be dislodged when sinus rhythm returns
2.Med-surg: cardiovascular & respiratory
Answer: C · Non-ST-elevation myocardial infarction
Why this is the answer
An NSTEMI is an acute coronary syndrome with myocardial necrosis (rising troponin) but no persistent ST elevation; ST depression or T wave inversion may be seen. It is treated with antiplatelets, anticoagulation and angiography based on risk, rather than emergency reperfusion.
Answer
C · Non-ST-elevation myocardial infarction
3.Med-surg: neuro, endocrine & renal
Answer: B · Heparin is often used to stop the circuit from clotting
Why this is the answer
Heparin is commonly used during haemodialysis to prevent clotting in the circuit. Its effect can cause prolonged bleeding from puncture sites, so procedures such as IM injections may be timed with care.
Answer
B · Heparin is often used to stop the circuit from clotting
4.Med-surg: neuro, endocrine & renal
Answer: B · A patient on insulin for DKA whose potassium is now 2.9 mmol/L
Why this is the answer
Insulin drives potassium into cells, and a potassium of 2.9 mmol/L during DKA treatment can cause life-threatening arrhythmias. The insulin rate and potassium replacement need urgent review under the protocol. The other patients are stable.
Answer
B · A patient on insulin for DKA whose potassium is now 2.9 mmol/L
5.Med-surg: GI, perioperative & oncology
Answer: D · Ulnar nerve
Why this is the answer
The ulnar nerve runs superficially at the elbow and is a common site of positioning injury. Careful padding and avoiding pressure on the elbow help prevent numbness and weakness of the hand.
Answer
D · Ulnar nerve
6.Med-surg: GI, perioperative & oncology
Answer: A · Use the spill kit with PPE, clean up, bag as cytotoxic waste and report
Why this is the answer
Cytotoxic spills are managed using a dedicated spill kit with gloves, gown, eye protection and a mask as needed. The spill is contained, absorbed and cleaned from the outside in, waste is placed in labelled cytotoxic waste and the incident is reported.
Answer
A · Use the spill kit with PPE, clean up, bag as cytotoxic waste and report
7.Clinical nursing
Answer: C · Sitting the patient upright and supporting them to clear secretions
Why this is the answer
An upright position improves lung expansion, and adequate fluids, deep breathing and coughing help clear sputum. Oxygen is given to target saturations if needed.
Answer
C · Sitting the patient upright and supporting them to clear secretions
8.Clinical nursing
Answer: B · A patient with new-onset confusion and a respiratory rate of 28/min
Why this is the answer
New confusion with tachypnoea suggests acute deterioration, such as sepsis or hypoxia. Patients with stable chronic problems can wait.
Answer
B · A patient with new-onset confusion and a respiratory rate of 28/min
9.Lab values & electrolytes
Answer: A · Put seizure precautions in place and monitor neurological status
Why this is the answer
Hyponatremia can cause cerebral edema and seizures. The nurse monitors neurological status, takes seizure precautions and reports the result. Extra water and thiazides can lower the sodium further.Checked against:Low blood sodium · MedlinePlus (NIH) (2025)
Answer
A · Put seizure precautions in place and monitor neurological status
10.Lab values & electrolytes
Answer: C · Nephrotic syndrome
Why this is the answer
Nephrotic syndrome is heavy proteinuria with low albumin, edema and high lipids. Low albumin reduces oncotic pressure, causing edema, and the liver increases lipoprotein production. There is also a higher risk of clots and infection.Checked against:Nephrotic syndrome · MedlinePlus (NIH) (2025)
Answer
C · Nephrotic syndrome
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.24: acidaemia (below 7.35)
PaCO₂ 24 mmHg: low (35–45)
HCO₃⁻ 10 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·9 + 8 = 21.5 → 19.5–23.5 mmHg
Compare
measured: 22 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: QTc = 0.49 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 12 × 0.04 = 0.48 s
RR = 24 × 0.04 = 0.96 s
Bazett’s formula
QTc = 0.48/√0.96 = 0.48/0.9798 = 0.49 s
Answer
QTc = 0.49 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (490 ms)
14.ECG rhythm strip interpretation
Answer: third-degree (complete) AV block
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: R–R = 31 small boxes, 1500 ÷ 31 ≈ 48 per minute.
2. Rhythm: R–R regular (1.24 s) and P–P regular (0.76 s), but the two are independent.
3. P waves: upright and regular at 79 per minute, but not linked to the QRS complexes; some hide in a QRS or a T wave.
4. PR interval: varies from beat to beat; there is no fixed relation.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
third-degree (complete) AV block
Answer
third-degree (complete) AV block
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: D · A patient with asthma who is using accessory muscles and has an SpO₂ of 88%
Why this is the answer
Accessory muscle use and low SpO₂ in asthma show acute respiratory distress, a breathing problem. The raised glucose, moderate pain and a fever already being treated are real but less urgent.
Answer
D · A patient with asthma who is using accessory muscles and has an SpO₂ of 88%
16.Prioritization & delegation
Answer: A · Treat for hypoglycemia with fast-acting oral carbohydrate
Why this is the answer
When in doubt, treat as hypoglycemia. A little sugar will not harm a patient with high glucose, but untreated hypoglycemia can cause brain injury within minutes, and insulin could be fatal.
Answer
A · Treat for hypoglycemia with fast-acting oral carbohydrate