Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A woman had lymph nodes removed from her left armpit for breast cancer. Which advice helps reduce the risk of lymphoedema?
AUse only the left arm for heavy lifting to build up its muscles
BKeep the left arm hanging down and as still as possible all day
CApply tight jewellery to the left wrist
DAvoid BP cuffs and injections on the left arm where possible
2.Med-surg: cardiovascular & respiratoryHard
A patient being treated for infective endocarditis of the mitral valve suddenly develops slurred speech and weakness of the right arm. What is the most likely cause?
ALow blood glucose from a reduced appetite
BA side effect of the IV antibiotic on the nerves
CA migraine aura triggered by the fever
DAn embolus from a valve vegetation causing a stroke
3.Med-surg: neuro, endocrine & renalMedium
A patient with atrial fibrillation has had an ischaemic stroke. Which long-term medicine type most reduces the risk of another stroke?
AA proton pump inhibitor
BA beta-agonist inhaler
CA loop diuretic
DAn oral anticoagulant
4.Med-surg: neuro, endocrine & renalHard
A patient on levothyroxine has palpitations, weight loss and poor sleep. TSH is suppressed, and free T4 is high. What is the most likely explanation?
AThe dose is too high
BA normal response to the drug
CThe dose is too low
DThe thyroid has stopped working
5.Med-surg: GI, perioperative & oncologyMedium
Which neutrophil count indicates severe neutropenia?
AAbove 10 × 109/L
BAbove 2.0 × 109/L
CBelow 7.5 × 109/L
DBelow 0.5 × 109/L
6.Med-surg: GI, perioperative & oncologyHard
A patient with diabetes has a foot ulcer. A sterile probe touches bone at the base of the ulcer. What should the nurse suspect?
AA healing category 1 ulcer
BSimple dry skin
COsteomyelitis
DVenous insufficiency
7.Clinical nursingMedium
A patient with sickle cell disease is admitted with a painful crisis. What is a key early nursing priority?
AApplying cold packs to the painful areas
BRestricting oral fluids
CGiving prompt, effective analgesia
DDelaying pain relief until a diagnosis is confirmed
8.Clinical nursingHard
A patient with full mental capacity decides against a treatment that the team thinks is best. What does the Mental Capacity Act 2005 (England and Wales) say?
AThe team may override any decision that it disagrees with if it is serious
BThe patient must be assessed by a psychiatrist before refusing
CThe family may make the decision instead if they disagree with the patient's choice
DA person is not treated as lacking capacity just because they make an unwise decision
9.Lab values & electrolytesMedium
A patient had a total thyroidectomy yesterday. Which laboratory value is most important to monitor in the first days after surgery?
ASerum sodium
BSerum calcium
CSerum potassium
DSerum glucose
10.Lab values & electrolytesHard
A patient with heavy alcohol use and a poor diet has a hemoglobin of 10.1 g/dL (101 g/L), an MCV of 110 fL and a low red cell folate. Which explanation fits best?
AThalassemia trait inherited from one of the parents
BAnemia caused by long-standing chronic kidney disease
CIron deficiency from slow, chronic bleeding in the gut
DFolate deficiency, made worse by a direct alcohol effect
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.36, PaCO₂ 57 mmHg (7.6 kPa) and HCO₃⁻ 31 mmol/L. The primary disorder is respiratory acidosis. How far is it compensated? Click your answer.
pH 7.36PaCO₂ 57 mmHg (7.6 kPa)HCO₃⁻ 31 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 138, Cl⁻ 107, HCO₃⁻ 18 mmol/L and albumin 15 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2junctional rhythm
3first-degree AV block
4normal sinus rhythm
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2paced rhythm, failure to capture
3idioventricular rhythm
4third-degree (complete) AV block
15.Prioritization & delegationMedium
A nurse teaches a patient with COPD pursed-lip breathing. Which statement shows a need for further teaching?
A“I will make my breath out about twice as long as my breath in.”
B“I will breathe out slowly through pursed lips.”
C“I will breathe in slowly through my nose.”
D“I will breathe in through my mouth and out quickly through my nose.”
16.Prioritization & delegationHard
Which patient needs airborne precautions rather than droplet precautions?
AA child with chickenpox (varicella)
BAn adult with influenza
CA child with pertussis (whooping cough)
DA teenager with mumps
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Avoid BP cuffs and injections on the left arm where possible
Why this is the answer
After axillary node removal, the arm's lymph drainage is reduced. Patients are advised to protect the skin, treat cuts promptly, avoid tight items and, where possible, avoid BP measurements, cannulation and injections on that arm. Gentle exercise helps lymph flow.
Answer
D · Avoid BP cuffs and injections on the left arm where possible
2.Med-surg: cardiovascular & respiratory
Answer: D · An embolus from a valve vegetation causing a stroke
Why this is the answer
Vegetations on the mitral or aortic valve can break off and embolise to the brain, kidneys, spleen or limbs. Sudden focal neurological signs suggest an embolic stroke: the nurse calls for urgent help, checks the blood glucose to exclude hypoglycaemia and expects urgent brain imaging. Thrombolysis is generally avoided in endocarditis because of the bleeding risk.
Answer
D · An embolus from a valve vegetation causing a stroke
3.Med-surg: neuro, endocrine & renal
Answer: D · An oral anticoagulant
Why this is the answer
In AF the main cause of stroke is a clot from the left atrium. Oral anticoagulants such as a DOAC or warfarin prevent this far better than antiplatelets. The start date after a stroke depends on its size and bleeding risk.
Answer
D · An oral anticoagulant
4.Med-surg: neuro, endocrine & renal
Answer: A · The dose is too high
Why this is the answer
A suppressed TSH with raised free T4 and hyperthyroid symptoms in a patient on levothyroxine suggests over-replacement. The prescriber usually lowers the dose. Long-term over-replacement increases the risk of atrial fibrillation and bone loss.
Answer
A · The dose is too high
5.Med-surg: GI, perioperative & oncology
Answer: D · Below 0.5 × 109/L
Why this is the answer
A neutrophil count below 0.5 × 109/L (500/mm³) is severe neutropenia, with a high risk of life-threatening infection. Fever in this setting is treated as neutropenic sepsis.
Answer
D · Below 0.5 × 109/L
6.Med-surg: GI, perioperative & oncology
Answer: C · Osteomyelitis
Why this is the answer
A positive probe-to-bone test in a diabetic foot ulcer strongly suggests osteomyelitis. Imaging, bone samples, prolonged antibiotics and specialist foot team care are usually needed.
Answer
C · Osteomyelitis
7.Clinical nursing
Answer: C · Giving prompt, effective analgesia
Why this is the answer
A sickle cell crisis needs rapid analgesia, often opioids, within a short target time, plus hydration, oxygen if hypoxic, warmth and monitoring for complications. Cold can trigger more sickling.
Answer
C · Giving prompt, effective analgesia
8.Clinical nursing
Answer: D · A person is not treated as lacking capacity just because they make an unwise decision
Why this is the answer
One of the Act's principles is that making an unwise decision is not, on its own, evidence of incapacity. The team should check understanding, explore reasons and document the discussion.
Answer
D · A person is not treated as lacking capacity just because they make an unwise decision
9.Lab values & electrolytes
Answer: B · Serum calcium
Why this is the answer
The parathyroid glands can be injured or removed during thyroidectomy, so parathyroid hormone falls and hypocalcemia can follow. The nurse monitors calcium and checks for tingling around the mouth, muscle cramps and Chvostek or Trousseau signs.Checked against:Hypoparathyroidism · MedlinePlus (NIH) (2026)
Answer
B · Serum calcium
10.Lab values & electrolytes
Answer: D · Folate deficiency, made worse by a direct alcohol effect
Why this is the answer
Poor diet and alcohol reduce folate intake and absorption, causing macrocytic anemia, and alcohol itself also raises the MCV. Iron deficiency and thalassemia cause small cells. Folate is replaced after B12 deficiency is excluded, and thiamine is also commonly given.Checked against:Folate-deficiency anemia - Medical Encyclopedia · MedlinePlus (NIH) (2026)
Answer
D · Folate deficiency, made worse by a direct alcohol effect
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.36: within 7.35–7.45
PaCO₂ 57 mmHg: high (35–45)
HCO₃⁻ 31 mmol/L: high (22–26)
Compensation
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: AGc = 19.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 138 − (107 + 18) = 13
Correction for albumin
13 + 0.25·(40 − 15) = 19.25 mmol/L
Answer
AGc = 19.25 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: junctional rhythm
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 34 small boxes, 1500 ÷ 34 ≈ 44 per minute.
2. Rhythm: regular, every R–R is 1.36 s.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
junctional rhythm
Answer
junctional rhythm
14.ECG rhythm strip interpretation
Answer: paced rhythm, failure to capture
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: 6 QRS complexes in 6 s, × 10 = 60 per minute.
2. Rhythm: the pacing spikes are regular (every 0.84 s), but the R–R is not, because a QRS is missing after some spikes.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.16 s and wide after the captured spikes; one spike is not followed by a QRS (no capture).
Interpretation
paced rhythm, failure to capture
Answer
paced rhythm, failure to capture
Failure to capture: the pacemaker fires but the heart does not respond. Textbooks treat it as urgent to report, because the patient may depend on the pacemaker.
15.Prioritization & delegation
Answer: D · “I will breathe in through my mouth and out quickly through my nose.”
Why this is the answer
Pursed-lip breathing means breathing in through the nose and out slowly through pursed lips, making exhalation longer. This keeps airways open and reduces air trapping.
Answer
D · “I will breathe in through my mouth and out quickly through my nose.”
16.Prioritization & delegation
Answer: A · A child with chickenpox (varicella)
Why this is the answer
Varicella spreads by the airborne route (and contact), so it needs an airborne infection isolation room. Influenza, pertussis and mumps are spread mainly by droplets.