Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A 34-year-old has hypertension that is hard to control and a low serum potassium without taking diuretics. Which cause should be considered?
AHypothyroidism
BPrimary hyperaldosteronism
CEssential hypertension of ageing
DIron-deficiency anaemia
2.Med-surg: cardiovascular & respiratoryHard
A patient with severe aortic stenosis is prescribed glyceryl trinitrate (nitroglycerin) for chest pain. Why should the nurse use particular caution?
AGTN makes the narrowed aortic valve tighten further within a few minutes
BGTN raises the blood pressure dangerously in aortic stenosis
CThere is no reason for caution, because GTN acts only on the coronary arteries
DVasodilators can cause a severe fall in BP with a fixed outflow obstruction
3.Med-surg: neuro, endocrine & renalMedium
Several hours after a carotid endarterectomy, which finding needs the most urgent action?
AAn expanding neck swelling with noisy breathing
BA small amount of dried blood on the dressing
CMild pain at the incision site
DA blood pressure slightly above the baseline
4.Med-surg: neuro, endocrine & renalHard
A nurse teaches a young adult with newly diagnosed epilepsy. Which statement shows a need for further teaching?
A"I will keep a record of any seizures I have."
B"As long as I take my tablets, I can swim alone."
C"I will take a shower rather than a bath."
D"I will tell my friends what to do if I have a seizure."
5.Med-surg: GI, perioperative & oncologyMedium
For how long are special precautions often taken with body fluids after many chemotherapy drugs?
AThey are never needed
BFor a whole year
CCommonly about 48 hours
DOnly during the infusion
6.Med-surg: GI, perioperative & oncologyHard
An older patient on regular opioids has small amounts of liquid stool leaking all day, but has not had a formed bowel movement for 6 days. What is the most likely cause?
AAcute infective gastroenteritis
BNormal stool pattern on opioids
CA flare of ulcerative colitis
DFaecal impaction with overflow
7.Clinical nursingMedium
A nurse suspects that an older patient is being financially abused by a relative. What should the nurse do?
AConfront the relative directly at the bedside about it
BRaise the concern through the local safeguarding (adult protection) procedure
CWait until the patient has been discharged
DKeep it secret because it is a family matter
8.Clinical nursingHard
A hypotensive postoperative patient is given a fluid bolus. Which findings suggest a good response?
AThe respiratory rate rises and new lung crackles appear
BThe heart rate falls, blood pressure rises and urine output improves
CThe capillary refill time becomes longer
DThe heart rate rises further and the patient becomes more confused
9.Lab values & electrolytesMedium
A patient on phenytoin has a level of 28 mcg/mL (usual range about 10–20 mcg/mL). Which findings would the nurse expect?
AHunger and weight gain
BNystagmus, unsteady gait and slurred speech
CTall, peaked T waves
DHyperactive behavior and insomnia only
10.Lab values & electrolytesHard
A trauma patient receives many units of blood quickly and then develops muscle twitching and low blood pressure. Which laboratory value is most likely to explain this?
AA high serum magnesium
BA high serum sodium
CA low serum glucose
DA low ionized calcium
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 14 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 14 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.28, PaCO₂ 24 mmHg (3.2 kPa), HCO₃⁻ 11 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.28PaCO₂ 24 mmHg (3.2 kPa)HCO₃⁻ 11 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
A patient without a palpable pulse has this organised rhythm on the monitor (pulseless electrical activity). Which treatment do adult resuscitation guidelines name for it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1transcutaneous pacing
2CPR (non-shockable rhythm)
3synchronised cardioversion
4immediate defibrillation
15.Prioritization & delegationMedium
A parent of a child with influenza talks with the nurse. Which statement shows a need for further teaching?
A“I will call if my child has trouble breathing.”
B“I will give my child aspirin to bring the fever down.”
C“I will keep my child home from school and away from others while unwell.”
D“I will give my child plenty of fluids.”
16.Prioritization & delegationHard
A child who had a tonsillectomy this morning is swallowing again and again while asleep. What should the nurse suspect?
AA sore throat from the breathing tube
BHunger after fasting for surgery
CNormal swallowing during sleep
DBleeding from the operation site
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Primary hyperaldosteronism
Why this is the answer
Excess aldosterone (for example from an adrenal adenoma, Conn's syndrome) causes sodium retention, hypertension and potassium loss. Young age, resistant hypertension and unexplained hypokalaemia suggest a secondary cause and need investigation.
Answer
B · Primary hyperaldosteronism
2.Med-surg: cardiovascular & respiratory
Answer: D · Vasodilators can cause a severe fall in BP with a fixed outflow obstruction
Why this is the answer
In severe aortic stenosis, cardiac output is fixed by the narrow valve. Vasodilators lower preload and afterload, and the heart cannot compensate, so the blood pressure can fall sharply and cause syncope. They are used with care and close monitoring.
Answer
D · Vasodilators can cause a severe fall in BP with a fixed outflow obstruction
3.Med-surg: neuro, endocrine & renal
Answer: A · An expanding neck swelling with noisy breathing
Why this is the answer
A neck haematoma after carotid surgery can compress the airway quickly. It needs immediate senior help and may need the wound opened. Neurological checks for new stroke and cranial nerve damage are also part of routine care.
Answer
A · An expanding neck swelling with noisy breathing
4.Med-surg: neuro, endocrine & renal
Answer: B · "As long as I take my tablets, I can swim alone."
Why this is the answer
People with epilepsy should never swim alone, even if their seizures are well controlled. Showers are safer than baths. Telling friends about first aid and keeping a seizure diary are good practice.
Answer
B · "As long as I take my tablets, I can swim alone."
5.Med-surg: GI, perioperative & oncology
Answer: C · Commonly about 48 hours
Why this is the answer
Many cytotoxic drugs are excreted in urine, faeces, vomit and other fluids for some time after administration. Local policies often require gloves and gowns for handling body fluids for about 48 hours, and longer for some drugs.
Answer
C · Commonly about 48 hours
6.Med-surg: GI, perioperative & oncology
Answer: D · Faecal impaction with overflow
Why this is the answer
Overflow diarrhoea occurs when liquid stool leaks around impacted faeces. Antidiarrhoeal drugs would worsen it; the nurse escalates for assessment, and treatment includes laxatives or enemas and review of the opioids.
Answer
D · Faecal impaction with overflow
7.Clinical nursing
Answer: B · Raise the concern through the local safeguarding (adult protection) procedure
Why this is the answer
Financial abuse is a form of adult abuse. Nurses report concerns through safeguarding procedures, document facts accurately and involve the patient as appropriate.
Answer
B · Raise the concern through the local safeguarding (adult protection) procedure
8.Clinical nursing
Answer: B · The heart rate falls, blood pressure rises and urine output improves
Why this is the answer
After a fluid challenge, a falling heart rate, rising blood pressure, better capillary refill, improving consciousness and urine output suggest fluid responsiveness. New crackles or breathlessness suggest fluid overload.
Answer
B · The heart rate falls, blood pressure rises and urine output improves
9.Lab values & electrolytes
Answer: B · Nystagmus, unsteady gait and slurred speech
Why this is the answer
Phenytoin toxicity causes nystagmus, ataxia, slurred speech and drowsiness. The nurse holds the dose and informs the prescriber. Low albumin increases the free (active) drug, so toxicity can occur even with a normal total level.
Answer
B · Nystagmus, unsteady gait and slurred speech
10.Lab values & electrolytes
Answer: D · A low ionized calcium
Why this is the answer
Stored blood contains citrate, which binds calcium. During massive transfusion, citrate can lower ionized calcium, causing tetany, hypotension and arrhythmias. Ionized calcium is monitored and replaced as prescribed.
Answer
D · A low ionized calcium
11.Arterial blood gas interpretation
Answer: PaCO₂ = 29 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·14 + 8 = 29 mmHg
range: 27–31 mmHg
Answer
PaCO₂ = 29 mmHg
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·11 + 8 = 24.5 → 22.5–26.5 mmHg
Compare
measured: 24 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: QTc = 0.465 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 9 × 0.04 = 0.36 s
RR = 15 × 0.04 = 0.60 s
Bazett’s formula
QTc = 0.36/√0.60 = 0.36/0.7746 = 0.465 s
Answer
QTc = 0.465 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (465 ms)
14.ECG rhythm strip interpretation
Answer: CPR (non-shockable rhythm)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 32 small boxes, 1500 ÷ 32 ≈ 47 per minute.
2. Rhythm: regular, every R–R is 1.28 s.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
junctional rhythm
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
CPR (non-shockable rhythm)
Answer
CPR (non-shockable rhythm)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: B · “I will give my child aspirin to bring the fever down.”
Why this is the answer
Aspirin in children with viral illnesses such as influenza or chickenpox is linked to Reye syndrome. Fluids, rest at home and reporting breathing trouble are correct.
Answer
B · “I will give my child aspirin to bring the fever down.”
16.Prioritization & delegation
Answer: D · Bleeding from the operation site
Why this is the answer
Frequent swallowing after tonsillectomy is a classic sign of bleeding. The nurse checks the throat with a light, looks at vital signs and reports at once.