Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with COPD is prescribed long-term oxygen therapy. How many hours a day is it usually needed to improve survival?
AOnly when walking outside
BAbout one hour each morning
COnly during meals
DAt least 15 hours a day
2.Med-surg: cardiovascular & respiratoryHard
Shortly after a thoracentesis, a patient becomes breathless with sharp chest pain and reduced breath sounds on the same side. What complication is most likely?
APneumothorax
BRe-accumulation of the effusion
CPulmonary embolism from the leg
DInfection at the puncture site
3.Med-surg: neuro, endocrine & renalMedium
A patient on insulin asks about drinking alcohol. Which advice is correct?
AAlcohol has no effect on blood glucose in people with diabetes
BAlcohol raises glucose, so extra insulin should be taken first
CAlcohol can cause hypos, even the next day, so eat carbs with it
DAlcohol should replace a meal on the days it is drunk
4.Med-surg: neuro, endocrine & renalHard
A patient with acute glomerulonephritis has a BP of 190/115 mmHg, a severe headache and blurred vision. Which is the priority?
AEncourage a walk to relieve the headache
BRecheck the BP at the next routine round
CGive extra oral fluids to correct the low urine output
DUrgent escalation for BP control and close neuro checks
5.Med-surg: GI, perioperative & oncologyMedium
Which monitoring is especially important for a patient receiving parenteral nutrition?
ABowel sounds and stool colour only
BPupil size and limb strength
CBlood glucose and signs of line infection
DPeak flow and visual acuity
6.Med-surg: GI, perioperative & oncologyHard
On day 3 after admission, a patient with alcohol dependence becomes confused, with hallucinations, sweating, tremor, fever and tachycardia. What is the most likely cause?
AHepatitis A caught on the ward
BAn allergic reaction to hospital food
CNormal anxiety about being in hospital
DDelirium tremens from alcohol withdrawal
7.Clinical nursingMedium
A patient without diabetes is started on high-dose prednisolone. Why might capillary blood glucose be monitored?
ASteroids make glucose meters inaccurate
BSteroids can raise the blood glucose
CSteroids always cause hypoglycaemia
DSteroids destroy the pancreas
8.Clinical nursingHard
A patient who speaks little English needs to give consent for a procedure. Their 14-year-old child offers to interpret. What is the best action?
AUse gestures and proceed
BArrange a professional interpreter
CAsk the patient to sign the form without explanation
DLet the child interpret to save time
9.Lab values & electrolytesMedium
An older adult takes lisinopril and furosemide and recently started daily ibuprofen for knee pain. The creatinine has risen from 1.0 to 1.8 mg/dL (88 to 159 µmol/L). What is the most likely cause?
AA laboratory error, since ibuprofen has no effect on the kidney
BNormal aging of the kidneys over a period of a few weeks
CMore activity has increased the patient's muscle mass quickly
DThe NSAID reduces kidney blood flow on top of the other two drugs
10.Lab values & electrolytesHard
A patient on clozapine reports a sore throat and fever. The ANC is 400/µL (0.4 × 10⁹/L). What should the nurse do?
AHold the clozapine and report the result at once
BHalve the dose and give it with a throat lozenge
CGive the dose with food to protect the stomach
DGive the next dose and recheck the ANC next month
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.48, PaCO₂ 25 mmHg (3.3 kPa) and HCO₃⁻ 18 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.48PaCO₂ 25 mmHg (3.3 kPa)HCO₃⁻ 18 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 142, Cl⁻ 106, HCO₃⁻ 17 mmol/L and albumin 19 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1supraventricular tachycardia (SVT)
2ventricular tachycardia
3accelerated junctional rhythm
4sinus tachycardia
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type II
2sinus bradycardia
3second-degree AV block type I (Wenckebach)
4third-degree (complete) AV block
15.Prioritization & delegationMedium
A patient with a head injury is being monitored. Which set of findings suggests rising intracranial pressure?
ALow temperature, fast breathing and a strong appetite
BNormal blood pressure, normal pulse and clear speech
CFalling blood pressure, a fast pulse and warm, flushed dry skin
DRising systolic pressure, slow pulse and irregular breathing
16.Prioritization & delegationHard
A patient with SIADH has a serum sodium of 120 mEq/L and is newly confused. Which nursing action has priority?
ATeaching the patient about a low-sodium diet at home
BEncouraging the patient to drink plenty of water
CSeizure precautions and close neurological checks
DHelping the patient to walk in the corridor alone
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · At least 15 hours a day
Why this is the answer
Long-term oxygen therapy improves survival in COPD with chronic hypoxaemia when used for at least 15 hours a day, including overnight. Patients must not smoke, because of the fire risk. Ambulatory oxygen for exercise is a separate assessment.
Answer
D · At least 15 hours a day
2.Med-surg: cardiovascular & respiratory
Answer: A · Pneumothorax
Why this is the answer
Pneumothorax is a common complication of thoracentesis, caused by the needle puncturing the lung or air entering the chest. The nurse assesses the patient, gives oxygen and informs the team, who will arrange a chest X-ray. An effusion re-accumulates over days, and infection appears later.
Answer
A · Pneumothorax
3.Med-surg: neuro, endocrine & renal
Answer: C · Alcohol can cause hypos, even the next day, so eat carbs with it
Why this is the answer
Alcohol reduces the liver's release of glucose, so it increases the risk of hypoglycaemia, which may be delayed for many hours. Patients should eat carbohydrate, check glucose before bed and tell friends that a hypo can look like drunkenness.
Answer
C · Alcohol can cause hypos, even the next day, so eat carbs with it
4.Med-surg: neuro, endocrine & renal
Answer: D · Urgent escalation for BP control and close neuro checks
Why this is the answer
Severe hypertension with headache and visual change suggests hypertensive encephalopathy. This needs urgent medical treatment and neurological monitoring. Seizures can occur.
Answer
D · Urgent escalation for BP control and close neuro checks
5.Med-surg: GI, perioperative & oncology
Answer: C · Blood glucose and signs of line infection
Why this is the answer
PN can cause hyperglycaemia and electrolyte disturbance, and the central line is a route for bloodstream infection. Glucose, electrolytes, fluid balance, weight and temperature are monitored closely.
Answer
C · Blood glucose and signs of line infection
6.Med-surg: GI, perioperative & oncology
Answer: D · Delirium tremens from alcohol withdrawal
Why this is the answer
Delirium tremens usually develops 2–3 days after stopping alcohol and is a medical emergency. It is treated with benzodiazepines, fluids, thiamine and close monitoring, ideally prevented by a withdrawal protocol.
Answer
D · Delirium tremens from alcohol withdrawal
7.Clinical nursing
Answer: B · Steroids can raise the blood glucose
Why this is the answer
Glucocorticoids increase glucose production and insulin resistance, causing steroid-induced hyperglycaemia. Glucose monitoring identifies patients who need treatment.
Answer
B · Steroids can raise the blood glucose
8.Clinical nursing
Answer: B · Arrange a professional interpreter
Why this is the answer
Professional interpreters provide accurate, impartial translation and protect confidentiality. Children and family members should not be used for important clinical discussions such as consent.
Answer
B · Arrange a professional interpreter
9.Lab values & electrolytes
Answer: D · The NSAID reduces kidney blood flow on top of the other two drugs
Why this is the answer
NSAIDs reduce prostaglandin-driven blood flow to the kidney. Combined with an ACE inhibitor and a diuretic, this can cause acute kidney injury, especially in older adults. The nurse reports the result and the NSAID is usually stopped.Checked against:Creatinine blood test · MedlinePlus (NIH) (2025)
Answer
D · The NSAID reduces kidney blood flow on top of the other two drugs
10.Lab values & electrolytes
Answer: A · Hold the clozapine and report the result at once
Why this is the answer
An ANC below 500/µL is severe neutropenia, and with fever and sore throat it suggests a serious infection. Clozapine is held, the provider is told immediately, and infection is assessed and treated. A nurse never changes a dose without a prescription.
Answer
A · Hold the clozapine and report the result at once
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.48: alkalaemia (above 7.45)
PaCO₂ 25 mmHg: low (35–45)
HCO₃⁻ 18 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: AGc = 24.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 142 − (106 + 17) = 19
Correction for albumin
19 + 0.25·(40 − 19) = 24.25 mmol/L
Answer
AGc = 24.25 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: supraventricular tachycardia (SVT)
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC. Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none visible; at this rate they are hidden in the QRS complexes or the T waves.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s), so the rhythm starts above the ventricles.
Interpretation
supraventricular tachycardia (SVT)
Answer
supraventricular tachycardia (SVT)
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 6 QRS complexes in 6 s, × 10 = 60 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.72 s, 83 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.14 s, wide (0.12 s or more).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: D · Rising systolic pressure, slow pulse and irregular breathing
Why this is the answer
Cushing’s triad (high systolic pressure with a widening pulse pressure, bradycardia and irregular respirations) is a late sign of raised intracranial pressure and needs urgent escalation.
Answer
D · Rising systolic pressure, slow pulse and irregular breathing
16.Prioritization & delegation
Answer: C · Seizure precautions and close neurological checks
Why this is the answer
Severe hyponatremia can cause seizures and falls. The nurse keeps the patient safe and reports changes; free water is restricted rather than encouraged, as prescribed.
Answer
C · Seizure precautions and close neurological checks