Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why must intravenous potassium chloride never be given as a rapid push or undiluted?
AIt immediately lowers the blood glucose to dangerous levels
BA sudden high potassium level can cause cardiac arrest
CIt turns into solid crystals inside the vein and blocks it
DIt works only when given by mouth
2.Med-surg: cardiovascular & respiratoryHard
Hours after surgery to restore blood flow to an ischaemic leg, the patient has severe calf pain that is worse when the toes are moved passively, and the calf feels tense. What should the nurse suspect?
AExpected postoperative pain from the leg wound
BCramp from lying still in bed
CA superficial thrombophlebitis of the long saphenous vein
DCompartment syndrome from reperfusion swelling
3.Med-surg: neuro, endocrine & renalMedium
A patient with gout has recurrent uric acid kidney stones. Which treatment helps prevent them?
ACalcium tablets and a low-fluid diet
BRestricting fluids in the evening only
CVitamin C supplements and a high-meat diet
DAllopurinol and making the urine less acidic
4.Med-surg: neuro, endocrine & renalHard
Which task for a patient with a urinary catheter can the nurse delegate to a healthcare assistant (nursing assistant)?
ADeciding whether the catheter can be removed
BAssessing a patient whose irrigation is not draining
CTeaching self-catheterisation for the first time
DEmptying the drainage bag and recording the volume
5.Med-surg: GI, perioperative & oncologyMedium
Which advice is appropriate for a patient with a very low platelet count?
AFloss hard every day to prevent gum disease
BUse a soft toothbrush and an electric razor
CTake aspirin regularly for headaches
DUse a razor blade for shaving every day
6.Med-surg: GI, perioperative & oncologyHard
At the end of an operation, the final count shows one swab missing. What should happen?
AClose the wound, as the swab was probably thrown away
BLet the patient leave and search the theatre later
CRecord the count as correct to avoid a delay
DTell the surgeon, search, and X-ray if it is not found
7.Clinical nursingMedium
What does HbA1c measure?
AInsulin levels after a meal
BBlood glucose at the moment of testing
CThe amount of ketones in the urine
DAverage blood glucose over roughly the previous two to three months
8.Clinical nursingHard
An older patient with delirium is trying to leave the ward at night, saying he must go home. What is the best initial approach?
AGive a sedative straight away without a prescription
BLet him leave, because adults can always do as they wish whatever their state
CPhysically restrain him in bed until the morning so that he cannot fall
DCalmly reassure and redirect him while the team assesses his capacity and safety
9.Lab values & electrolytesMedium
A patient has weight loss, tremor and heat intolerance. Which thyroid test pattern fits Graves disease?
ALow TSH with a high free T4
BHigh TSH with a normal free T4
CNormal TSH with a low free T4
DHigh TSH with a low free T4
10.Lab values & electrolytesHard
The nurse teaches a patient who is starting warfarin. Which statement shows a need for further teaching?
A"I will keep my intake of green leafy vegetables about the same"
B"I will tell my dentist and pharmacist that I take warfarin"
C"If I miss a dose, I will take two tablets the next day"
D"I will have my INR checked as often as I am told to"
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 59 mmHg (7.9 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a respiratory acidosis: pH 7.24, PaCO₂ 65 mmHg (8.7 kPa), HCO₃⁻ 27 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.24PaCO₂ 65 mmHg (8.7 kPa)HCO₃⁻ 27 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip. Which interpretation can you defend from this single strip? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
12:1 AV block (type undetermined)
2sinus bradycardia
3second-degree AV block type II
4first-degree AV block
15.Prioritization & delegationMedium
Before accessing a central venous catheter, what should the nurse do to prevent infection?
ATouch the hub to check it is clean
BRinse the hub with tap water and dry it
CBlow on the hub to remove any dust before connecting the syringe or line
DScrub the hub with an antiseptic such as chlorhexidine and let it dry
16.Prioritization & delegationHard
A patient admitted with suspected appendicitis says the pain suddenly got better, but now the abdomen is rigid and the heart rate is rising. What does this suggest?
AThe patient’s analgesic has finally started to work
BThe appendix may have ruptured, causing peritonitis
CThe pain has moved to a different, harmless place
DThe appendicitis is getting better without surgery
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · A sudden high potassium level can cause cardiac arrest
Why this is the answer
Rapid or concentrated IV potassium can cause cardiac arrest. It is given diluted, by infusion, at controlled rates (often with a pump and ECG monitoring for higher rates). Concentrated ampoules are tightly controlled in hospitals because of fatal errors.
Answer
B · A sudden high potassium level can cause cardiac arrest
2.Med-surg: cardiovascular & respiratory
Answer: D · Compartment syndrome from reperfusion swelling
Why this is the answer
When blood flow returns to ischaemic muscle, swelling can raise pressure in a fascial compartment. Pain out of proportion and pain on passive stretch are early signs; pulses may remain until late. It is reported urgently, as fasciotomy may be needed. The limb is kept at heart level, not raised high.
Answer
D · Compartment syndrome from reperfusion swelling
3.Med-surg: neuro, endocrine & renal
Answer: D · Allopurinol and making the urine less acidic
Why this is the answer
Uric acid stones form when urine is acidic and rich in uric acid. High fluid intake, alkalinising the urine (for example with potassium citrate) and allopurinol reduce the risk. Purine-rich foods are limited.
Answer
D · Allopurinol and making the urine less acidic
4.Med-surg: neuro, endocrine & renal
Answer: D · Emptying the drainage bag and recording the volume
Why this is the answer
Emptying and recording urine volume is routine and can be delegated to trained staff. Decisions about removal, assessment of a possible blockage and first-time teaching need the registered nurse.
Answer
D · Emptying the drainage bag and recording the volume
5.Med-surg: GI, perioperative & oncology
Answer: B · Use a soft toothbrush and an electric razor
Why this is the answer
With thrombocytopenia, the nurse reduces bleeding risk: soft toothbrush, electric razor, no NSAIDs or aspirin, avoiding IM injections and rectal procedures, and reporting bleeding, bruising or blood in urine or stool.
Answer
B · Use a soft toothbrush and an electric razor
6.Med-surg: GI, perioperative & oncology
Answer: D · Tell the surgeon, search, and X-ray if it is not found
Why this is the answer
Any discrepancy is reported immediately, the wound is checked before closure, the area and waste are searched, and an X-ray is taken if the item is not found. The event is documented and reported.
Answer
D · Tell the surgeon, search, and X-ray if it is not found
7.Clinical nursing
Answer: D · Average blood glucose over roughly the previous two to three months
Why this is the answer
HbA1c reflects glycation of haemoglobin over the life of red cells, giving an estimate of long-term glucose control.
Answer
D · Average blood glucose over roughly the previous two to three months
8.Clinical nursing
Answer: D · Calmly reassure and redirect him while the team assesses his capacity and safety
Why this is the answer
De-escalation, reorientation and supervision come first. If he lacks capacity, the team must act in his best interests using the least restrictive measures, following local law and policy.
Answer
D · Calmly reassure and redirect him while the team assesses his capacity and safety
9.Lab values & electrolytes
Answer: A · Low TSH with a high free T4
Why this is the answer
In Graves disease, antibodies stimulate the thyroid to make too much hormone. The high free T4 suppresses TSH from the pituitary through negative feedback, so TSH is low. A high TSH with a low T4 fits primary hypothyroidism.Checked against:TSH test · MedlinePlus (NIH) (2026); Thyroxine (T4) Test · MedlinePlus (NIH) (2024); Graves disease · MedlinePlus (NIH) (2026)
Answer
A · Low TSH with a high free T4
10.Lab values & electrolytes
Answer: C · "If I miss a dose, I will take two tablets the next day"
Why this is the answer
Doubling a missed warfarin dose can raise the INR and cause bleeding; the patient should follow the prescriber's instructions, usually taking the missed dose the same day or skipping it. A steady vitamin K intake, regular INR checks and telling other providers are correct.Checked against:Warfarin (drug information) · MedlinePlus (NIH) (2026)
Answer
C · "If I miss a dose, I will take two tablets the next day"
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 30.65 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|59 − 40| = 19 mmHg → 1.9 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·1.9 = 30.65 mmol/L
Answer
HCO₃⁻ = 30.65 mmol/L
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·2.5 = 26.5 mmol/L
chronic: 24 + 3.5·2.5 = 32.75 mmol/L
Compare
measured: 27 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: QTc = 0.417 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 23 × 0.04 = 0.92 s
Bazett’s formula
QTc = 0.40/√0.92 = 0.40/0.9592 = 0.417 s
Answer
QTc = 0.417 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (417 ms)
14.ECG rhythm strip interpretation
Answer: 2:1 AV block (type undetermined)
2:1 AV block: with two P waves for every QRS, no two conducted P waves follow each other, so you cannot see whether the PR would lengthen (type I) or stay constant (type II) before a non-conducted P wave. From one strip it is called a 2:1 AV block; a longer strip or a change in the conduction ratio decides the type. A narrow QRS makes type I more likely and a wide QRS type II, but neither proves it.
Five steps
1. Rate: R–R = 44 small boxes, 1500 ÷ 44 ≈ 34 per minute.
2. Rhythm: regular, every R–R is 1.76 s.
3. P waves: upright and regular (P–P 0.88 s, 68 per minute), two for every QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.14 s, wide (0.12 s or more).
Why the type stays open
Every second P wave is not conducted, so no two conducted beats follow each other and a lengthening PR could never show.
2:1 AV block (type undetermined)
Answer
2:1 AV block (type undetermined)
A narrow QRS makes type I more likely and a wide QRS type II, but only a longer strip or a change in the conduction ratio decides.
15.Prioritization & delegation
Answer: D · Scrub the hub with an antiseptic such as chlorhexidine and let it dry
Why this is the answer
Scrubbing the needleless connector with an antiseptic, such as chlorhexidine or alcohol, and letting it dry reduces central line infections. Aseptic technique is used for every access.
Answer
D · Scrub the hub with an antiseptic such as chlorhexidine and let it dry
16.Prioritization & delegation
Answer: B · The appendix may have ruptured, causing peritonitis
Why this is the answer
A sudden ease in pain followed by a rigid abdomen and a rising pulse can mean rupture and peritonitis. This is a surgical emergency, so the nurse reports at once.
Answer
B · The appendix may have ruptured, causing peritonitis