Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which ECG finding is typical of atrial flutter?
AP waves with no relationship to the QRS complexes
BWide, bizarre QRS complexes at 180/min
CA chaotic baseline with no clear P waves and irregular QRS
DRegular sawtooth flutter waves between QRS complexes
2.Med-surg: cardiovascular & respiratoryHard
A patient with pneumonia on high-flow nasal oxygen at 50 L/min with FiO₂ 0.6 has SpO₂ 90%, RR 34/min and is using accessory muscles. What is the most appropriate action?
AEscalate urgently to critical care for review of respiratory support
BContinue the same support and recheck in four hours
CChange to a nasal cannula at 4 L/min to reduce nasal dryness
DLay the patient flat so they can rest the breathing muscles
3.Med-surg: neuro, endocrine & renalMedium
A patient with AKI has a urinary catheter that drains nothing. Which quick bedside check helps rule out a post-renal cause?
ASend a urine sample for culture and wait for the laboratory result
BGive a large bolus of IV fluid straight away
CEncourage the patient to drink two litres of water
DCheck the catheter for kinks or blockage and do a bladder scan
4.Med-surg: neuro, endocrine & renalHard
A patient with Parkinson's disease becomes agitated and confused at night. Which newly prescribed drug should the nurse question?
AParacetamol (acetaminophen)
BMelatonin
CHaloperidol
DLactulose
5.Med-surg: GI, perioperative & oncologyMedium
Why is an ankle-brachial pressure index (ABPI) measured before compression bandaging for a leg ulcer?
ATo check for a leg bone fracture
BTo find the bacteria in the wound
CTo exclude significant arterial disease
DTo find out how deep the ulcer is
6.Med-surg: GI, perioperative & oncologyHard
A patient on warfarin has a major upper GI bleed with an INR of 5. Which treatment should the nurse anticipate to reverse the warfarin?
AProthrombin complex concentrate with IV vitamin K
BMore warfarin to stabilise the INR
COral aspirin to balance the clotting system quickly
DProtamine sulfate on its own
7.Clinical nursingMedium
What is the first-line drug treatment for anaphylaxis?
AInhaled steroid
BOral antihistamine such as cetirizine
CIntravenous paracetamol
DIntramuscular adrenaline
8.Clinical nursingHard
Which task is most appropriate for a registered nurse to delegate to a trained healthcare assistant (unlicensed assistive personnel)?
AMeasuring and recording vital signs on a stable patient
BTeaching a patient to inject insulin for the first time
CGiving a dose of intravenous antibiotic
DAssessing a patient who has just reported new chest pain
9.Lab values & electrolytesMedium
A patient is scheduled for a liver biopsy. Which laboratory results should the nurse check before the procedure?
ATSH and free T4
BPlatelet count and PT/INR
CHbA1c and lipid panel
DSerum sodium and chloride
10.Lab values & electrolytesHard
A patient with acute kidney injury has a potassium of 6.8 mEq/L despite medical treatment, a pH of 7.12 and pulmonary edema not responding to diuretics. Which treatment is most likely needed?
AMore oral fluid
BUrgent dialysis
CA potassium supplement
DAn IV magnesium dose
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.42, PaCO₂ 58 mmHg (7.7 kPa) and HCO₃⁻ 36 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.42PaCO₂ 58 mmHg (7.7 kPa)HCO₃⁻ 36 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.17, PaCO₂ 31 mmHg (4.1 kPa), HCO₃⁻ 11 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.17PaCO₂ 31 mmHg (4.1 kPa)HCO₃⁻ 11 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A patient with asthma uses a peak flow meter. A reading below 50% of personal best is in the red zone. Which statement shows correct understanding?
A“I will use my reliever inhaler and get emergency help straight away.”
B“I will stop all my inhalers until the reading is back up.”
C“I will go for a short run to open up my lungs.”
D“I will wait until tomorrow morning to see if the reading gets better on its own.”
16.Prioritization & delegationHard
During birth, the baby’s head delivers but the shoulders do not follow. What should the nurse do first?
AAsk the mother to stop pushing and wait an hour
BPush firmly on the top of the uterus (fundal pressure)
CPull hard on the baby’s head and neck to free the trapped shoulders quickly
DHelp with the McRoberts position and give suprapubic pressure as directed
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Regular sawtooth flutter waves between QRS complexes
Why this is the answer
Atrial flutter is caused by a re-entry circuit in the right atrium, giving regular sawtooth flutter waves, often at about 300/min with 2:1 block (ventricular rate about 150/min). A chaotic baseline with irregular QRS is atrial fibrillation. Like AF, it carries a stroke risk.
Answer
D · Regular sawtooth flutter waves between QRS complexes
2.Med-surg: cardiovascular & respiratory
Answer: A · Escalate urgently to critical care for review of respiratory support
Why this is the answer
High oxygen requirements with tachypnoea and increased work of breathing despite high-flow oxygen indicate worsening respiratory failure. Early critical care review is needed for escalation such as CPAP, NIV or intubation. Reducing support or waiting risks a respiratory arrest.
Answer
A · Escalate urgently to critical care for review of respiratory support
3.Med-surg: neuro, endocrine & renal
Answer: D · Check the catheter for kinks or blockage and do a bladder scan
Why this is the answer
A blocked or kinked catheter or a distended bladder can cause or mimic anuria. Checking the tubing, flushing or changing the catheter as permitted and performing a bladder scan quickly identify obstruction. Ultrasound of the kidneys looks for higher obstruction such as hydronephrosis.
Answer
D · Check the catheter for kinks or blockage and do a bladder scan
4.Med-surg: neuro, endocrine & renal
Answer: C · Haloperidol
Why this is the answer
Haloperidol is a dopamine antagonist and can severely worsen parkinsonian symptoms. Metoclopramide is avoided for the same reason. Causes of delirium should be looked for, and specialist advice is needed if a drug is required.
Answer
C · Haloperidol
5.Med-surg: GI, perioperative & oncology
Answer: C · To exclude significant arterial disease
Why this is the answer
ABPI compares ankle and arm systolic pressures. A low ABPI suggests arterial disease, where compression could cause ischaemia, so assessment is needed before compression therapy.
Answer
C · To exclude significant arterial disease
6.Med-surg: GI, perioperative & oncology
Answer: A · Prothrombin complex concentrate with IV vitamin K
Why this is the answer
Major bleeding on warfarin is treated by stopping it and giving prothrombin complex concentrate for rapid reversal with IV vitamin K for a lasting effect. Protamine reverses heparin, not warfarin.
Answer
A · Prothrombin complex concentrate with IV vitamin K
7.Clinical nursing
Answer: D · Intramuscular adrenaline
Why this is the answer
Adrenaline IM into the thigh (for adults typically 0.5 mg, i.e. 0.5 mL of 1 mg/mL; US guidance 0.3–0.5 mg) is first line, repeated after 5 minutes if needed. Antihistamines and steroids are not first-line treatments.
Answer
D · Intramuscular adrenaline
8.Clinical nursing
Answer: A · Measuring and recording vital signs on a stable patient
Why this is the answer
Routine observations on a stable patient are within the role of a trained assistant, with the nurse remaining accountable and reviewing the results. Assessment of new symptoms, IV medicines and initial teaching need registered nurse skills.
Answer
A · Measuring and recording vital signs on a stable patient
9.Lab values & electrolytes
Answer: B · Platelet count and PT/INR
Why this is the answer
Liver biopsy carries a risk of bleeding, and liver disease often lowers platelets and clotting factors. Platelets and PT/INR are checked beforehand, and abnormal results are reported so they can be corrected or the procedure postponed.Checked against:Liver biopsy · MedlinePlus (NIH) (2025)
Answer
B · Platelet count and PT/INR
10.Lab values & electrolytes
Answer: B · Urgent dialysis
Why this is the answer
Indications for urgent dialysis in AKI include refractory hyperkalemia, severe metabolic acidosis, fluid overload not responding to diuretics, uremic complications and some poisonings. This patient has three of them.Checked against:Acute tubular necrosis · MedlinePlus (NIH) (2025)
Answer
B · Urgent dialysis
11.Arterial blood gas interpretation
Answer: fully compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.42: within 7.35–7.45
PaCO₂ 58 mmHg: high (35–45)
HCO₃⁻ 36 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 44.2–48.2 mmHg, so the measured 58 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
fully compensated
Answer
fully compensated
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·11 + 8 = 24.5 → 22.5–26.5 mmHg
Compare
measured: 31 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: QTc = 0.411 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 23 × 0.04 = 0.92 s
Fridericia’s formula
QTc = 0.40/∛0.92 = 0.40/0.9726 = 0.411 s
Answer
QTc = 0.411 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (411 ms)
14.ECG rhythm strip interpretation
Answer: PR interval
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 23 small boxes, 1500 ÷ 23 ≈ 65 per minute.
2. Rhythm: regular, every R–R is 0.92 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.32 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
PR interval → first-degree AV block
Answer
PR interval
15.Prioritization & delegation
Answer: A · “I will use my reliever inhaler and get emergency help straight away.”
Why this is the answer
A red-zone reading means a severe flare. The patient uses their quick-relief inhaler as in their action plan and seeks emergency care at once.
Answer
A · “I will use my reliever inhaler and get emergency help straight away.”
16.Prioritization & delegation
Answer: D · Help with the McRoberts position and give suprapubic pressure as directed
Why this is the answer
In shoulder dystocia, the McRoberts maneuver (flexing the mother’s thighs onto her abdomen) and suprapubic pressure help free the shoulder. Fundal pressure and pulling on the head can worsen the injury.
Answer
D · Help with the McRoberts position and give suprapubic pressure as directed