Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why must intravenous potassium chloride never be given as a rapid push or undiluted?
AIt turns into solid crystals inside the vein and blocks it
BIt works only when given by mouth
CIt immediately lowers the blood glucose to dangerous levels
DA sudden high potassium level can cause cardiac arrest
2.Med-surg: cardiovascular & respiratoryHard
A nurse teaches a patient who has a new permanent pacemaker. Which statement shows a need for further teaching?
A"I will carry my pacemaker identification card with me at all times."
B"I will keep my mobile phone in my shirt pocket over the device."
C"I will tell staff about the device before any MRI scan."
D"I will keep my follow-up appointments for device checks."
3.Med-surg: neuro, endocrine & renalMedium
After IV thrombolysis for stroke, which observations are most important in the first 24 hours?
AHourly peak flow and oxygen saturation
BBowel sounds and abdominal girth hourly
CFrequent neurological checks and BP
DDaily weight and the fluid balance only
4.Med-surg: neuro, endocrine & renalHard
A patient on long-term high-dose prednisolone is three days after bowel surgery. They report only mild abdominal pain, but the heart rate has risen to 115/min and the temperature is 37.4 °C. Why should the nurse be especially concerned?
ASteroids protect against infection, so sepsis is very unlikely
BSteroids can mask fever, pain and peritonism, hiding complications
CThe mild pain shows that the bowel is healing as expected
DSteroids cause tachycardia in all patients, so no action is needed
5.Med-surg: GI, perioperative & oncologyMedium
When is cold therapy most useful for pain?
ASoon after an acute soft tissue injury, to reduce swelling
BDirectly on skin with poor circulation
COver numb areas where sensation is lost
DFor long-term muscle stiffness, applied continuously for several hours
6.Med-surg: GI, perioperative & oncologyHard
A worker has a hydrofluoric acid burn on the hand and severe pain. After irrigation with water, which specific treatment is commonly applied?
ASodium bicarbonate paste
BSilver sulfadiazine cream
CIce cubes wrapped in a cloth
DCalcium gluconate gel
7.Clinical nursingMedium
What does HbA1c measure?
ABlood glucose at the moment of testing
BThe amount of ketones in the urine
CAverage blood glucose over roughly the previous two to three months
DInsulin levels after a meal
8.Clinical nursingHard
Why should "units" never be abbreviated to "U" or "IU" on an insulin prescription?
APharmacists cannot dispense insulin written that way
BIt changes the type of insulin given
CThe letters can be misread as a zero, causing a tenfold overdose
DThe abbreviation is only allowed on prescriptions for children
9.Lab values & electrolytesMedium
A patient with recurrent gout starts allopurinol. Which laboratory result shows that the treatment is achieving its goal?
AA falling serum potassium
BA falling serum uric acid
CA rising white cell count
DA rising serum calcium
10.Lab values & electrolytesHard
A patient with jaundice and nausea has a positive IgM antibody to hepatitis A virus (IgM anti-HAV). What does this show?
APast hepatitis B infection that has cleared
BImmunity from hepatitis A vaccine long ago
CA current or recent hepatitis A infection
DChronic hepatitis A lasting many years
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.50, PaCO₂ 49 mmHg (6.5 kPa) and HCO₃⁻ 37 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.50PaCO₂ 49 mmHg (6.5 kPa)HCO₃⁻ 37 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 32 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 32 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
This lead II strip shows atrial flutter with a fixed conduction ratio. Find the ventricular rate in beats per minute.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
ventricular rate = bpm
14.ECG rhythm strip interpretationHard
A monitored patient is found unresponsive and not breathing normally, and no carotid pulse can be felt. The monitor shows this organised rhythm. What is this situation called? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1pulseless electrical activity (PEA)
2asystole
3sinus bradycardia
4ventricular fibrillation
15.Prioritization & delegationMedium
On a mixed medical unit, which patient should the nurse see first?
AA patient with hypertension whose blood pressure is 136/84 mmHg
BA patient with a mild tension headache who is asking for acetaminophen
CA patient asking for written information about tomorrow’s discharge
DA patient with depression who has given away his belongings and has a suicide plan
16.Prioritization & delegationHard
Four patients arrive at the emergency department at the same time. Who should be seen first?
AA young adult with a swollen, painful ankle after a fall on the stairs
BA child with a temperature of 39 °C who is alert and drinking
CAn adult with kidney stone pain of 9/10 and stable vital signs
DAn older adult with weakness on one side that began 40 minutes ago
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · A sudden high potassium level can cause cardiac arrest
Why this is the answer
Rapid or concentrated IV potassium can cause cardiac arrest. It is given diluted, by infusion, at controlled rates (often with a pump and ECG monitoring for higher rates). Concentrated ampoules are tightly controlled in hospitals because of fatal errors.
Answer
D · A sudden high potassium level can cause cardiac arrest
2.Med-surg: cardiovascular & respiratory
Answer: B · "I will keep my mobile phone in my shirt pocket over the device."
Why this is the answer
Patients are advised to keep mobile phones at least about 15 cm from the device and to hold them to the opposite ear. They carry a device card, tell staff before MRI or surgery (diathermy) and attend follow-up checks. Normal household appliances are generally safe.
Answer
B · "I will keep my mobile phone in my shirt pocket over the device."
3.Med-surg: neuro, endocrine & renal
Answer: C · Frequent neurological checks and BP
Why this is the answer
Neurological observations, blood pressure and checks for bleeding are done frequently after thrombolysis. A new headache, vomiting, falling GCS or rising blood pressure may indicate haemorrhage. Antiplatelets and anticoagulants are usually avoided for 24 hours.
Answer
C · Frequent neurological checks and BP
4.Med-surg: neuro, endocrine & renal
Answer: B · Steroids can mask fever, pain and peritonism, hiding complications
Why this is the answer
Long-term steroids blunt fever, pain and abdominal rigidity, so an anastomotic leak, abscess or perforation may present only with subtle signs such as tachycardia. The nurse should assess thoroughly and escalate early. These patients also need steroid cover around surgery to prevent adrenal crisis.
Answer
B · Steroids can mask fever, pain and peritonism, hiding complications
5.Med-surg: GI, perioperative & oncology
Answer: A · Soon after an acute soft tissue injury, to reduce swelling
Why this is the answer
Cold reduces swelling, bleeding and nerve conduction in acute injuries. It is wrapped and applied for short periods and avoided on areas with poor circulation or sensation. Heat is better for muscle spasm and stiffness.
Answer
A · Soon after an acute soft tissue injury, to reduce swelling
6.Med-surg: GI, perioperative & oncology
Answer: D · Calcium gluconate gel
Why this is the answer
Hydrofluoric acid penetrates deeply and binds calcium and magnesium, causing severe pain and possible life-threatening hypocalcaemia. Calcium gluconate gel binds fluoride; serum calcium and heart rhythm are monitored in larger exposures.
Answer
D · Calcium gluconate gel
7.Clinical nursing
Answer: C · Average blood glucose over roughly the previous two to three months
Why this is the answer
HbA1c reflects glycation of haemoglobin over the life of red cells, giving an estimate of long-term glucose control.
Answer
C · Average blood glucose over roughly the previous two to three months
8.Clinical nursing
Answer: C · The letters can be misread as a zero, causing a tenfold overdose
Why this is the answer
"U" can be misread as 0, so "10U" might be read as 100, and "IU" can be mistaken for "IV" or "10". Writing "units" in full is a standard safety rule (ISMP), because insulin errors can cause severe hypoglycaemia.
Answer
C · The letters can be misread as a zero, causing a tenfold overdose
9.Lab values & electrolytes
Answer: B · A falling serum uric acid
Why this is the answer
Allopurinol reduces uric acid production by blocking xanthine oxidase. Over time, a lower serum uric acid reduces gout attacks and dissolves urate crystals. Kidney function is checked, and a rash must be reported because of rare severe skin reactions.Checked against:Gout · StatPearls (NCBI Bookshelf) (2026)
Answer
B · A falling serum uric acid
10.Lab values & electrolytes
Answer: C · A current or recent hepatitis A infection
Why this is the answer
IgM antibodies appear early, so IgM anti-HAV indicates acute hepatitis A. IgG anti-HAV alone shows past infection or vaccination and lifelong immunity. Hepatitis A does not become chronic and spreads by the fecal-oral route, so hand hygiene is essential.Checked against:Hepatitis A · MedlinePlus (NIH) (2025)
Answer
C · A current or recent hepatitis A infection
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.50: alkalaemia (above 7.45)
PaCO₂ 49 mmHg: high (35–45)
HCO₃⁻ 37 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 44.9–48.9 mmHg, so the measured 49 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: PaCO₂ = 43.4 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·32 + 21 = 43.4 mmHg
Answer
PaCO₂ = 43.4 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: ventricular rate = 63 bpm
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Flutter waves
F–F = 6 small boxes = 0.24 s → 1500 ÷ 6 = 250 per minute
QRS complexes
R–R = 24 small boxes = 0.96 s → 1500 ÷ 24 = 63 per minute
conduction ratio = 250 ÷ 63 = 4:1
Answer
ventricular rate = 63 bpm
14.ECG rhythm strip interpretation
Answer: pulseless electrical activity (PEA)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 34 small boxes, 1500 ÷ 34 ≈ 44 per minute.
2. Rhythm: regular, every R–R is 1.36 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.20 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
sinus bradycardia
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
pulseless electrical activity (PEA)
Answer
pulseless electrical activity (PEA)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: D · A patient with depression who has given away his belongings and has a suicide plan
Why this is the answer
Giving away belongings and having a plan are warning signs of suicide, an immediate safety threat. The other patients are stable and their needs can wait.
Answer
D · A patient with depression who has given away his belongings and has a suicide plan
16.Prioritization & delegation
Answer: D · An older adult with weakness on one side that began 40 minutes ago
Why this is the answer
Sudden one-sided weakness suggests a stroke, and treatment depends on how quickly it starts. Severe kidney stone pain needs prompt pain relief, but the patient is stable.
Answer
D · An older adult with weakness on one side that began 40 minutes ago