Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A pulse oximeter on a patient's finger gives an unreliable, flickering reading. Which factor is the most likely cause?
AThe patient having eaten recently
BA regular heart rate of 75 beats per minute
CCold hands with poor peripheral circulation
DThe patient sitting upright in a chair
2.Med-surg: cardiovascular & respiratoryHard
A day after a myocardial infarction, a patient has frequent ventricular ectopic beats on the monitor. Which blood results should be checked first?
APotassium and magnesium
BAmylase and lipase
CFerritin and vitamin B12
DAlbumin and bilirubin
3.Med-surg: neuro, endocrine & renalMedium
A patient has radioactive iodine treatment for hyperthyroidism. Which advice is correct?
ALimit close contact with children and pregnant women for a time
BThere are no precautions, because the dose is tiny
CStay in strict isolation in hospital for several months
DStart breastfeeding again the next day
4.Med-surg: neuro, endocrine & renalHard
A patient has fever, confusion, odd behaviour and a new seizure. Herpes simplex encephalitis is suspected. Which drug is usually started straight away?
AOral amoxicillin
BOral prednisolone
CIV insulin
DIV aciclovir
5.Med-surg: GI, perioperative & oncologyMedium
Which initial treatment is usual for symptomatic hypercalcaemia of malignancy?
AFluid restriction and a thiazide diuretic
BOral calcium tablets and vitamin D
CA high-calcium diet with extra milk
DIV fluids followed by an IV bisphosphonate
6.Med-surg: GI, perioperative & oncologyHard
A patient finds daily wound dressing changes very painful. What is the most effective nursing approach?
ADo the dressing quickly and give analgesia afterwards
BChange the dressing less often than the plan says
CGive analgesia timed so it works during the dressing change
DAvoid analgesia so the patient can report any problems during the change
7.Clinical nursingMedium
After a laparoscopic cholecystectomy, a patient has pain in the shoulder tip. What is the most likely cause?
AAn allergic reaction to the dressing
BGas used during the operation irritating the diaphragm
CA broken collarbone from being moved onto the table
DA heart attack caused by the stress of surgery
8.Clinical nursingHard
Why must blood samples for a cross-match be labelled at the bedside immediately after they are taken?
ATo speed up the laboratory's computer system and reduce the waiting time
BTo let the patient sign the label
CTo prevent "wrong blood in tube" errors that can cause fatal reactions
DTo keep the sample warm so the cells do not break down in transit
9.Lab values & electrolytesMedium
An older adult takes lisinopril and furosemide and recently started daily ibuprofen for knee pain. The creatinine has risen from 1.0 to 1.8 mg/dL (88 to 159 µmol/L). What is the most likely cause?
AThe NSAID reduces kidney blood flow on top of the other two drugs
BNormal aging of the kidneys over a period of a few weeks
CMore activity has increased the patient's muscle mass quickly
DA laboratory error, since ibuprofen has no effect on the kidney
10.Lab values & electrolytesHard
A patient without symptoms has a TSH of 7.5 mIU/L on two occasions with a normal free T4. Which term fits best?
ASubclinical hyperthyroidism
BOvert primary hypothyroidism
CSubclinical hypothyroidism
DSecondary hypothyroidism
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 6 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 6 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 35% oxygen shows PaO₂ 71 mmHg (9.5 kPa) and PaCO₂ 46 mmHg (6.1 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1normal sinus rhythm
2sinus rhythm with PVCs
3second-degree AV block type II
4sinus rhythm with sinus arrest
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2second-degree AV block type II
3third-degree (complete) AV block
4sinus bradycardia
15.Prioritization & delegationMedium
A nurse who usually works in obstetrics floats to an adult medical unit. Which patient is most appropriate to assign to this nurse?
AA patient on a continuous insulin infusion for diabetic ketoacidosis
BA patient with a new tracheostomy
CA patient with pneumonia who is stable on oral antibiotics
DA patient with an active upper gastrointestinal bleed
16.Prioritization & delegationHard
An older patient with heart failure is receiving a second unit of blood. She becomes breathless, with crackles in both lungs and a rising blood pressure. What is most likely happening?
ATransfusion-associated circulatory overload
BAn expected effect of the first unit
CHypoglycemia caused by the stored blood product
DA mild allergic reaction with hives
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Cold hands with poor peripheral circulation
Why this is the answer
Poor perfusion (cold, shock, vasoconstriction), movement, dark nail varnish or bright ambient light can make readings unreliable. The nurse checks the waveform, warms the hand or uses an ear probe, and compares the reading with the clinical picture.
Answer
C · Cold hands with poor peripheral circulation
2.Med-surg: cardiovascular & respiratory
Answer: A · Potassium and magnesium
Why this is the answer
Low potassium and low magnesium both increase ventricular irritability and the risk of VT and VF after an MI. They are checked and corrected, usually keeping potassium in the upper part of the normal range. The patient is also assessed for ischaemia and haemodynamic change.
Answer
A · Potassium and magnesium
3.Med-surg: neuro, endocrine & renal
Answer: A · Limit close contact with children and pregnant women for a time
Why this is the answer
After radioiodine, patients are advised to limit close and prolonged contact, especially with young children and pregnant women, for a period set by the department. It is contraindicated in pregnancy and breastfeeding.
Answer
A · Limit close contact with children and pregnant women for a time
4.Med-surg: neuro, endocrine & renal
Answer: D · IV aciclovir
Why this is the answer
Herpes simplex encephalitis is treatable but can cause severe brain damage. IV aciclovir is started as soon as it is suspected, without waiting for test results. Kidney function and hydration are monitored during treatment.
Answer
D · IV aciclovir
5.Med-surg: GI, perioperative & oncology
Answer: D · IV fluids followed by an IV bisphosphonate
Why this is the answer
Hypercalcaemia causes polyuria and dehydration, so IV saline is given first, then a bisphosphonate such as zoledronic acid to reduce bone resorption. Calcium, kidney function and symptoms are monitored.
Answer
D · IV fluids followed by an IV bisphosphonate
6.Med-surg: GI, perioperative & oncology
Answer: C · Give analgesia timed so it works during the dressing change
Why this is the answer
Procedural pain is best managed by giving analgesia so its peak effect matches the procedure. Non-adherent dressings, soaking adherent dressings and allowing the patient to call pauses also help.
Answer
C · Give analgesia timed so it works during the dressing change
7.Clinical nursing
Answer: B · Gas used during the operation irritating the diaphragm
Why this is the answer
Carbon dioxide used to inflate the abdomen can irritate the diaphragm, causing referred shoulder-tip pain. It usually settles within a few days with mobilisation and analgesia.
Answer
B · Gas used during the operation irritating the diaphragm
8.Clinical nursing
Answer: C · To prevent "wrong blood in tube" errors that can cause fatal reactions
Why this is the answer
A sample labelled with the wrong patient's details can lead to incompatible blood being issued. Labelling at the bedside after positive identification is a key transfusion safety step.
Answer
C · To prevent "wrong blood in tube" errors that can cause fatal reactions
9.Lab values & electrolytes
Answer: A · The NSAID reduces kidney blood flow on top of the other two drugs
Why this is the answer
NSAIDs reduce prostaglandin-driven blood flow to the kidney. Combined with an ACE inhibitor and a diuretic, this can cause acute kidney injury, especially in older adults. The nurse reports the result and the NSAID is usually stopped.Checked against:Creatinine blood test · MedlinePlus (NIH) (2025)
Answer
A · The NSAID reduces kidney blood flow on top of the other two drugs
10.Lab values & electrolytes
Answer: C · Subclinical hypothyroidism
Why this is the answer
A raised TSH with a normal free T4 is subclinical hypothyroidism; the pituitary is working harder to keep T4 normal. Overt hypothyroidism has a low free T4, and subclinical hyperthyroidism has a low TSH.Checked against:TSH (Thyroid-stimulating hormone) Test · MedlinePlus (NIH) (2024)
Answer
C · Subclinical hypothyroidism
11.Arterial blood gas interpretation
Answer: PaCO₂ = 17 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·6 + 8 = 17 mmHg
range: 15–19 mmHg
Answer
PaCO₂ = 17 mmHg
12.Arterial blood gas interpretation
Answer: A–a gradient = 121 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC. Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: regular (R–R 0.96 s) except for one pause of 2.32 s, which is not a whole number of P–P cycles.
3. P waves: upright, one before every QRS; no P wave at all during the pause.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
sinus rhythm with sinus arrest
Answer
sinus rhythm with sinus arrest
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.76 s, 79 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.12 s, wide (0.12 s or more).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: C · A patient with pneumonia who is stable on oral antibiotics
Why this is the answer
A float nurse should receive stable patients whose care uses general skills. A new tracheostomy, an active bleed and an insulin infusion for DKA need unit-specific experience and close monitoring.
Answer
C · A patient with pneumonia who is stable on oral antibiotics
16.Prioritization & delegation
Answer: A · Transfusion-associated circulatory overload
Why this is the answer
Breathlessness, crackles and hypertension during a transfusion in a patient with heart failure suggest circulatory overload. The nurse stops the transfusion, sits the patient up, gives oxygen as prescribed and informs the provider, who may prescribe a diuretic.