Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which statement about a spacer for a metered-dose inhaler is correct?
ALess coordination is needed, and more drug reaches the lungs
BIt makes each puff of the drug stronger than usual
CIt means the steroid preventer inhaler can be stopped altogether
DIt is designed to be used with dry-powder inhalers
2.Med-surg: cardiovascular & respiratoryHard
A nurse teaches a patient how to measure blood pressure at home. Which statement shows a need for further teaching?
A"I will measure it straight after my morning jog."
B"I will take two readings and write them both down."
C"I will sit with my back supported and my arm at heart level."
D"I will rest quietly for five minutes before measuring."
3.Med-surg: neuro, endocrine & renalMedium
Several hours after a carotid endarterectomy, which finding needs the most urgent action?
AA blood pressure slightly above the baseline
BAn expanding neck swelling with noisy breathing
CA small amount of dried blood on the dressing
DMild pain at the incision site
4.Med-surg: neuro, endocrine & renalHard
A patient on a variable rate IV insulin infusion is nil by mouth. Why is a glucose-containing IV fluid usually given alongside it?
ATo prevent hypoglycaemia while insulin is running
BTo speed up the action of the insulin in the muscles
CTo stop the insulin sticking to the IV tubing
DTo replace the potassium lost from the cells
5.Med-surg: GI, perioperative & oncologyMedium
What is the main treatment for a venous leg ulcer with an adequate arterial supply?
AStrong oral antibiotics for all ulcers
BCompression therapy
CSurgery to amputate the limb
DKeeping the leg hanging down all day
6.Med-surg: GI, perioperative & oncologyHard
During a nasogastric feed, a patient starts coughing and SpO₂ falls from 96% to 89%. What should the nurse do first?
ALay the patient flat to help them rest
BStop the feed and assess the airway and breathing
CIncrease the feed rate to finish it sooner
DGive a drink of water to clear the throat
7.Clinical nursingMedium
A patient with heart failure has pink, frothy sputum and crackles throughout both lungs. What is happening?
AAcute pulmonary oedema
BAsthma attack
CPneumothorax
DUpper gastrointestinal bleeding
8.Clinical nursingHard
Why might a patient with diabetes who takes a beta-blocker not notice hypoglycaemia early?
ABeta-blockers can mask warning signs such as tremor and a fast heart rate
BBeta-blockers raise blood glucose, so true hypoglycaemia cannot happen at all
CBeta-blockers make the patient sleep through the night
DBeta-blockers stop the liver from responding to insulin
9.Lab values & electrolytesMedium
A patient on levothyroxine has palpitations, weight loss and a TSH of 0.05 mIU/L. What is the most likely explanation?
AThe thyroid is now completely normal
BThe levothyroxine dose is too high
CThe patient has stopped the drug
DThe levothyroxine dose is too low
10.Lab values & electrolytesHard
The nurse teaches a patient about the HbA1c test. Which statement shows a need for further teaching?
A"The test shows my average glucose over the past few months"
B"A lower result means less risk of damage to my eyes and kidneys"
C"My daily finger-stick readings still matter between the tests"
D"I must not eat anything for 12 hours before the HbA1c test"
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 135 mmol/L, glucose 31.2 mmol/L and urea 17.7 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 135 mmol/Lglucose 31.2 mmol/Lurea 17.7 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.27, PaCO₂ 27 mmHg (3.6 kPa), HCO₃⁻ 12 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.27PaCO₂ 27 mmHg (3.6 kPa)HCO₃⁻ 12 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A drowsy patient who has just returned from surgery starts to vomit. What should the nurse do first?
ATurn the patient onto their side
BGive a drink of water
CGive an oral anti-sickness tablet
DRaise the legs above the heart
16.Prioritization & delegationHard
An infant with pyloric stenosis has repeated projectile vomiting. Which acid-base imbalance is most likely?
AMetabolic alkalosis
BRespiratory alkalosis
CMetabolic acidosis
DRespiratory acidosis
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Less coordination is needed, and more drug reaches the lungs
Why this is the answer
A spacer slows the aerosol and holds it so the patient can inhale it with slow breaths. More drug reaches the lungs and less is deposited in the mouth. It is used with pressurised metered-dose inhalers, not dry-powder devices.
Answer
A · Less coordination is needed, and more drug reaches the lungs
2.Med-surg: cardiovascular & respiratory
Answer: A · "I will measure it straight after my morning jog."
Why this is the answer
Home readings should be taken after resting quietly for about 5 minutes, sitting with back supported, feet flat and the arm supported at heart level, with no recent exercise, caffeine or smoking. Two readings are often recorded. Measuring after exercise gives falsely high results.
Answer
A · "I will measure it straight after my morning jog."
3.Med-surg: neuro, endocrine & renal
Answer: B · An expanding neck swelling with noisy breathing
Why this is the answer
A neck haematoma after carotid surgery can compress the airway quickly. It needs immediate senior help and may need the wound opened. Neurological checks for new stroke and cranial nerve damage are also part of routine care.
Answer
B · An expanding neck swelling with noisy breathing
4.Med-surg: neuro, endocrine & renal
Answer: A · To prevent hypoglycaemia while insulin is running
Why this is the answer
Without food, an insulin infusion can push glucose too low. A substrate fluid containing glucose is run with the insulin, and glucose is checked hourly so the rate can be adjusted.
Answer
A · To prevent hypoglycaemia while insulin is running
5.Med-surg: GI, perioperative & oncology
Answer: B · Compression therapy
Why this is the answer
Graduated compression reduces venous hypertension and oedema and speeds healing. Leg elevation, exercise and treating the underlying vein disease also help.
Answer
B · Compression therapy
6.Med-surg: GI, perioperative & oncology
Answer: B · Stop the feed and assess the airway and breathing
Why this is the answer
Coughing and desaturation suggest aspiration or a displaced tube. The feed is stopped, the patient is sat up, oxygen is given as needed, and medical review and checking of tube position follow.
Answer
B · Stop the feed and assess the airway and breathing
7.Clinical nursing
Answer: A · Acute pulmonary oedema
Why this is the answer
Acute pulmonary oedema causes severe breathlessness, crackles and frothy sputum. Sit the patient up, give oxygen and call urgently for medical help; diuretics are commonly given.
Answer
A · Acute pulmonary oedema
8.Clinical nursing
Answer: A · Beta-blockers can mask warning signs such as tremor and a fast heart rate
Why this is the answer
Tremor, palpitations and anxiety in hypoglycaemia are driven by the sympathetic system, which beta-blockers blunt. Sweating is often still present, and patients need to monitor glucose closely.
Answer
A · Beta-blockers can mask warning signs such as tremor and a fast heart rate
9.Lab values & electrolytes
Answer: B · The levothyroxine dose is too high
Why this is the answer
A very low TSH with symptoms of excess thyroid hormone suggests over-replacement. The dose is usually reduced, because long-term over-replacement raises the risk of atrial fibrillation and bone loss, especially in older adults.Checked against:TSH test · MedlinePlus (NIH) (2026)
Answer
B · The levothyroxine dose is too high
10.Lab values & electrolytes
Answer: D · "I must not eat anything for 12 hours before the HbA1c test"
Why this is the answer
HbA1c reflects glucose attached to hemoglobin over about 2–3 months, so fasting is not needed. Lower HbA1c values are linked to fewer microvascular complications, and home glucose monitoring is still useful for day-to-day decisions.Checked against:The A1C Test & Diabetes · NIDDK (NIH) (2018); Hemoglobin A1C (HbA1c) Test · MedlinePlus (NIH) (2025)
Answer
D · "I must not eat anything for 12 hours before the HbA1c test"
11.Arterial blood gas interpretation
Answer: Osm = 319 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·135 + 31.2 + 17.7 = 318.9 ≈ 319 mOsm/kg
Answer
Osm = 319 mOsm/kg
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·12 + 8 = 26 → 24–28 mmHg
Compare
measured: 27 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: pause = 1.68 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
42 small boxes from R to R across the pause
Convert
pause = 42 × 0.04 s = 1.68 s
Compare with P–P
1.68 ÷ 0.72 ≈ 2.3 P–P cycles, not a whole number
Answer
pause = 1.68 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: rate
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 32 small boxes, 1500 ÷ 32 ≈ 47 per minute.
2. Rhythm: regular, every R–R is 1.28 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
rate → sinus bradycardia
Answer
rate
15.Prioritization & delegation
Answer: A · Turn the patient onto their side
Why this is the answer
A drowsy patient who vomits can aspirate. Turning them to the side lets vomit drain from the mouth; suction and a prescribed antiemetic follow.
Answer
A · Turn the patient onto their side
16.Prioritization & delegation
Answer: A · Metabolic alkalosis
Why this is the answer
Repeated vomiting of stomach contents loses hydrochloric acid, causing metabolic alkalosis, often with low chloride and potassium. Fluids and electrolytes are corrected before surgery.