Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A nurse measures blood pressure on a large upper arm using a cuff that is too small. What effect will this have?
AThe reading will be falsely low
BThe reading will be accurate but slower
COnly the pulse rate will be affected
DThe reading will be falsely high
2.Med-surg: cardiovascular & respiratoryHard
A patient with infective endocarditis is on IV gentamicin with another antibiotic. Which monitoring is most important?
ABlood glucose only
BLiver size by daily palpation and weekly abdominal ultrasound
CDrug levels, renal function and hearing or balance changes
DPeak flow readings and spirometry before and after each dose
3.Med-surg: neuro, endocrine & renalMedium
A week after thyroid surgery, a patient's voice is still hoarse and weak. Which complication is most likely?
ADamage to a recurrent laryngeal nerve
BAn allergic reaction to the adhesive dressing tape
CA thyroid storm caused by surgery
DLow calcium from parathyroid injury
4.Med-surg: neuro, endocrine & renalHard
During an alteplase infusion for stroke, the patient develops a severe headache, vomiting and a falling GCS. What should the nurse do first?
AStop the infusion and call the stroke team urgently
BGive a sedative to settle the patient and continue
CSpeed up the infusion so that it finishes sooner
DGive an antiemetic and recheck the GCS in an hour's time
5.Med-surg: GI, perioperative & oncologyMedium
A day after a spinal anaesthetic, a patient has a headache that is worse when sitting up and better when lying flat. What is the most likely cause?
AMigraine caused by hospital lighting
BRaised blood pressure from pain
CPost-dural puncture headache
DA side effect of the antibiotic
6.Med-surg: GI, perioperative & oncologyHard
On day 2 after upper abdominal surgery, a patient has a temperature of 37.8 °C, SpO₂ 93% on air and reduced breath sounds at both bases. They have not used their incentive spirometer because of pain. What is the most appropriate nursing plan?
AStop all analgesia so that the patient can cough more strongly
BGive oxygen at 15 L/min and leave the patient to rest quietly
CBetter pain control, sitting up, deep breathing, mobilising and reporting
DKeep the patient in bed and restrict movement until the fever settles
7.Clinical nursingMedium
After thyroid surgery, a patient has tingling around the mouth and muscle cramps. Which electrolyte problem should be suspected?
AHypocalcaemia
BHypermagnesaemia
CHypernatraemia
DHyperkalaemia
8.Clinical nursingHard
A patient with central chest pain has ST elevation on the 12-lead ECG. What is the main aim of urgent treatment?
AStarting a cholesterol-lowering drug before any other treatment is given
BRestoring blood flow through the blocked coronary artery quickly
CStrict bed rest for several days before deciding on treatment
DWaiting for the troponin result before taking any action
9.Lab values & electrolytesMedium
A patient's levothyroxine dose was changed today. When is the TSH usually rechecked?
AAfter about 6–8 weeks
BAfter about 24 hours
CAfter about 1 year
DAfter about 3 days
10.Lab values & electrolytesHard
A patient on high-dose dexamethasone has a white cell count of 15 × 10³/µL, mostly mature neutrophils with no bands. They have no fever and no signs of infection. What is the most likely explanation?
ACertain sepsis that needs antibiotics started without delay
BA new leukemia that is confirmed by this result alone
CA laboratory error, because steroids always lower the white count
DA steroid effect that moves neutrophils into the circulating blood
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.20, PaCO₂ 16 mmHg (2.1 kPa) and HCO₃⁻ 6 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.20PaCO₂ 16 mmHg (2.1 kPa)HCO₃⁻ 6 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 32 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 32 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2first-degree AV block
3normal sinus rhythm
4sinus tachycardia
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1junctional rhythm
2asystole
3third-degree (complete) AV block
4ventricular fibrillation
15.Prioritization & delegationMedium
Which practice makes a shift handover safest?
AA quick chat in the corridor with no notes taken
BA structured format, such as SBAR, with time for questions
CLeaving a sticky note on the computer screen for the next nurse
DHanding over only the patients who had problems during the shift
16.Prioritization & delegationHard
A patient receiving comfort-focused end-of-life care is distressed by breathlessness. Which approach is most appropriate?
AStart a series of aggressive tests to find the exact cause of the breathlessness
BLeave the patient alone so they can rest
CGive prescribed opioids and use positioning and a fan to relieve breathlessness
DWithhold all opioids because they may slow breathing
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · The reading will be falsely high
Why this is the answer
A cuff that is too small needs a higher pressure to compress the brachial artery, giving a falsely high reading. A cuff that is too large can give a falsely low reading. The bladder should encircle most of the arm, so cuff size is chosen by arm circumference.
Answer
D · The reading will be falsely high
2.Med-surg: cardiovascular & respiratory
Answer: C · Drug levels, renal function and hearing or balance changes
Why this is the answer
Gentamicin is nephrotoxic and ototoxic. Levels are measured to guide dosing, renal function is checked regularly and patients are asked about tinnitus, hearing loss and dizziness. Risk is greater with loop diuretics, older age and longer courses.
Answer
C · Drug levels, renal function and hearing or balance changes
3.Med-surg: neuro, endocrine & renal
Answer: A · Damage to a recurrent laryngeal nerve
Why this is the answer
The recurrent laryngeal nerves run close to the thyroid and supply most of the laryngeal muscles. Injury causes hoarseness; bilateral injury can cause stridor and airway obstruction. Mild hoarseness from intubation usually settles within days. Parathyroid injury causes hypocalcaemia with tingling and cramps.
Answer
A · Damage to a recurrent laryngeal nerve
4.Med-surg: neuro, endocrine & renal
Answer: A · Stop the infusion and call the stroke team urgently
Why this is the answer
New headache, vomiting, hypertension or neurological deterioration during or after thrombolysis may indicate symptomatic intracranial haemorrhage. The infusion is stopped, urgent medical review arranged and an urgent CT scan and coagulation tests anticipated.
Answer
A · Stop the infusion and call the stroke team urgently
5.Med-surg: GI, perioperative & oncology
Answer: C · Post-dural puncture headache
Why this is the answer
CSF leaking through the dural puncture lowers pressure and causes a positional headache. Fluids, simple analgesia and caffeine may help, and the anaesthetist is informed; an epidural blood patch is sometimes needed.
Answer
C · Post-dural puncture headache
6.Med-surg: GI, perioperative & oncology
Answer: C · Better pain control, sitting up, deep breathing, mobilising and reporting
Why this is the answer
Basal atelectasis is common after upper abdominal surgery when pain limits deep breathing. Good analgesia, upright positioning, deep breathing exercises, incentive spirometry, supported coughing and early mobilisation re-expand the lungs. The findings are reported, because they may progress to pneumonia; oxygen is given to target if needed.
Answer
C · Better pain control, sitting up, deep breathing, mobilising and reporting
7.Clinical nursing
Answer: A · Hypocalcaemia
Why this is the answer
Damage to the parathyroid glands lowers calcium, causing perioral tingling, tetany and positive Chvostek or Trousseau signs.
Answer
A · Hypocalcaemia
8.Clinical nursing
Answer: B · Restoring blood flow through the blocked coronary artery quickly
Why this is the answer
ST-elevation myocardial infarction means a coronary artery is usually completely blocked. Urgent reperfusion by primary PCI, or thrombolysis if PCI is not available in time, limits the amount of heart muscle that dies.
Answer
B · Restoring blood flow through the blocked coronary artery quickly
9.Lab values & electrolytes
Answer: A · After about 6–8 weeks
Why this is the answer
Levothyroxine has a half-life of about a week, so a steady state takes about 6 weeks. The TSH is therefore rechecked about 6–8 weeks after a dose change; checking earlier gives a misleading result.Checked against:Hypothyroidism · MedlinePlus (NIH) (2024)
Answer
A · After about 6–8 weeks
10.Lab values & electrolytes
Answer: D · A steroid effect that moves neutrophils into the circulating blood
Why this is the answer
Corticosteroids raise the neutrophil count by releasing marginated neutrophils and slowing their exit from the blood, usually without a left shift. The nurse still assesses carefully, because steroids can also hide the usual signs of infection.
Answer
D · A steroid effect that moves neutrophils into the circulating blood
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.20: acidaemia (below 7.35)
PaCO₂ 16 mmHg: low (35–45)
HCO₃⁻ 6 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: PaCO₂ = 43.4 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·32 + 21 = 43.4 mmHg
Answer
PaCO₂ = 43.4 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: sinus bradycardia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 35 small boxes, 1500 ÷ 35 ≈ 43 per minute.
2. Rhythm: regular, every R–R is 1.40 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.20 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
sinus bradycardia
Answer
sinus bradycardia
14.ECG rhythm strip interpretation
Answer: asystole
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: none; an almost flat line.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
asystole
Answer
asystole
A flat line is always checked: look at the patient, the leads and the gain, and view a second lead, because a loose electrode or fine VF can look like asystole.
15.Prioritization & delegation
Answer: B · A structured format, such as SBAR, with time for questions
Why this is the answer
Handover is a high-risk moment for errors. A structured format and the chance to ask questions help the next nurse understand each patient’s condition and priorities.
Answer
B · A structured format, such as SBAR, with time for questions
16.Prioritization & delegation
Answer: C · Give prescribed opioids and use positioning and a fan to relieve breathlessness
Why this is the answer
In palliative care, opioids are used to relieve breathlessness, along with positioning, a fan and calm reassurance. The aim is comfort, not more investigations.
Answer
C · Give prescribed opioids and use positioning and a fan to relieve breathlessness