Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with heart failure starts dapagliflozin, an SGLT2 inhibitor. Which teaching is most relevant?
AAvoid drinking any fluids at all for the first week of treatment
BKeep the genital area clean, as fungal infections are more common
CExpect the urine to turn bright orange and stain underwear and clothes
DTake an extra dose if the ankles swell
2.Med-surg: cardiovascular & respiratoryHard
A patient has new chest pain at rest. The ECG shows ST depression, but serial troponins remain normal. Which diagnosis fits best?
ANon-ST-elevation myocardial infarction
BST-elevation myocardial infarction
CUnstable angina
DStable angina
3.Med-surg: neuro, endocrine & renalMedium
Which measure best prevents catheter-associated urinary tract infection?
AChange the catheter for a new one every day
BDisconnect the bag regularly to empty it
CKeep the drainage bag above bladder level
DRemove the catheter as soon as it is no longer needed
4.Med-surg: neuro, endocrine & renalHard
A patient with a severe head injury does not open the eyes, and in response to pain the arms extend and rotate inwards with the legs extended. What does this indicate?
AA focal seizure that will stop without any treatment
BFlexor (decorticate) posturing, a sign of mild cortical injury
CExtensor (decerebrate) posturing: severe brainstem injury
DA normal withdrawal response to a painful stimulus
5.Med-surg: GI, perioperative & oncologyMedium
Dysphagia that started with solids and now includes liquids, with weight loss, most suggests which cause?
ASimple anxiety about swallowing tablets
BNormal ageing of the swallowing muscles
CA narrowing such as an oesophageal tumour
DA dry mouth from drinking too little water
6.Med-surg: GI, perioperative & oncologyHard
Two days after a PEG insertion, a patient reports pain on feeding, and feed is leaking around the site. What should the nurse do?
AGive the next medicines through the tube as usual
BStop the feed at once and seek urgent medical advice
CIncrease the feed rate to improve nutrition
DContinue feeding and apply a thicker dressing
7.Clinical nursingMedium
A patient taking a statin reports unexplained muscle pain and weakness. What should the nurse do?
AReassure them that this is a sign the drug is working
BReport it, as statins can cause muscle damage
CTell them to double the dose
DAdvise more vigorous exercise to work through it
8.Clinical nursingHard
Why are liquid medicines for nasogastric tubes drawn up in dedicated enteral (oral) syringes rather than IV syringes?
ATo prevent accidental intravenous administration
BEnteral syringes measure doses less accurately
CIV syringes cannot hold liquid medicines
DEnteral syringes keep the medicine sterile
9.Lab values & electrolytesMedium
A patient has weight loss, tremor and heat intolerance. Which thyroid test pattern fits Graves disease?
ANormal TSH with a low free T4
BHigh TSH with a normal free T4
CLow TSH with a high free T4
DHigh TSH with a low free T4
10.Lab values & electrolytesHard
A patient has painless jaundice, itching, dark urine and pale stools. ALP is markedly raised, conjugated (direct) bilirubin is high and ALT is only mildly raised. What is the most likely cause?
AIncreased breakdown of red blood cells (hemolytic anemia)
BGilbert syndrome, a harmless inherited bilirubin disorder
CBlockage of bile flow, for example by a tumor in the bile duct
DAcute viral hepatitis with widespread liver cell damage
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 16 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 16 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 30 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 30 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1torsades de pointes
2ventricular tachycardia
3supraventricular tachycardia (SVT)
4atrial flutter, 2:1 conduction
15.Prioritization & delegationMedium
During labor, the nurse sees the umbilical cord in the vagina after the membranes rupture. What is the first action?
AWait for the next contraction before acting
BRelieve pressure on the cord by lifting the presenting part with a gloved hand
CPush the cord back into the uterus
DAsk the patient to walk around the room to bring the baby lower and speed up labor
16.Prioritization & delegationHard
During a power cut, which patient is the nurse’s first priority?
AA patient watching television when it switched off
BA patient whose bed will not raise electrically
CA patient who depends on a ventilator
DA patient whose call light is not working
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Keep the genital area clean, as fungal infections are more common
Why this is the answer
SGLT2 inhibitors increase glucose loss in the urine, raising the risk of genital thrush and urinary infections. They also cause mild diuresis, and in people with diabetes there is a rare risk of ketoacidosis, so they are paused during acute illness as advised. They improve outcomes in heart failure.
Answer
B · Keep the genital area clean, as fungal infections are more common
2.Med-surg: cardiovascular & respiratory
Answer: C · Unstable angina
Why this is the answer
Unstable angina is new, worsening or rest angina without a troponin rise. It is an acute coronary syndrome and is managed urgently because it can progress to infarction. Stable angina is predictable and exertional. NSTEMI has a rising troponin.
Answer
C · Unstable angina
3.Med-surg: neuro, endocrine & renal
Answer: D · Remove the catheter as soon as it is no longer needed
Why this is the answer
The risk of CAUTI rises with each day a catheter is in place. Avoiding unnecessary catheters and removing them early are the most effective measures. A closed system and keeping the bag below bladder level also help.
Answer
D · Remove the catheter as soon as it is no longer needed
4.Med-surg: neuro, endocrine & renal
Answer: C · Extensor (decerebrate) posturing: severe brainstem injury
Why this is the answer
Abnormal extension to pain (GCS motor score 2) indicates severe injury at or near the brainstem and carries a worse prognosis than abnormal flexion (decorticate posturing, motor score 3). Any new abnormal posturing needs immediate escalation.
Answer
C · Extensor (decerebrate) posturing: severe brainstem injury
5.Med-surg: GI, perioperative & oncology
Answer: C · A narrowing such as an oesophageal tumour
Why this is the answer
Progressive dysphagia, solids first then liquids, with weight loss, is typical of a mechanical obstruction such as oesophageal cancer or a stricture. It needs an urgent referral for endoscopy.
Answer
C · A narrowing such as an oesophageal tumour
6.Med-surg: GI, perioperative & oncology
Answer: B · Stop the feed at once and seek urgent medical advice
Why this is the answer
Pain on feeding, external leakage or new bleeding soon after PEG insertion may mean feed is leaking into the peritoneum. Feeding and medicines are stopped immediately and senior review is arranged to exclude peritonitis.
Answer
B · Stop the feed at once and seek urgent medical advice
7.Clinical nursing
Answer: B · Report it, as statins can cause muscle damage
Why this is the answer
Statins can cause myopathy and, rarely, rhabdomyolysis. Unexplained muscle symptoms should be reported so creatine kinase can be checked and the drug reviewed.
Answer
B · Report it, as statins can cause muscle damage
8.Clinical nursing
Answer: A · To prevent accidental intravenous administration
Why this is the answer
Giving an oral or enteral medicine intravenously can be fatal. Enteral syringes with non-IV connectors, such as ENFit, make this wrong-route error much less likely.
Answer
A · To prevent accidental intravenous administration
9.Lab values & electrolytes
Answer: C · Low TSH with a high free T4
Why this is the answer
In Graves disease, antibodies stimulate the thyroid to make too much hormone. The high free T4 suppresses TSH from the pituitary through negative feedback, so TSH is low. A high TSH with a low T4 fits primary hypothyroidism.Checked against:TSH test · MedlinePlus (NIH) (2026); Thyroxine (T4) Test · MedlinePlus (NIH) (2024); Graves disease · MedlinePlus (NIH) (2026)
Answer
C · Low TSH with a high free T4
10.Lab values & electrolytes
Answer: C · Blockage of bile flow, for example by a tumor in the bile duct
Why this is the answer
In obstruction, conjugated bilirubin backs up into the blood and is passed in the urine, making it dark, while stools are pale and ALP rises. Hemolysis and Gilbert syndrome raise unconjugated bilirubin; hepatitis raises ALT much more.Checked against:Bilirubin in Urine · MedlinePlus (NIH) (2024)
Answer
C · Blockage of bile flow, for example by a tumor in the bile duct
11.Arterial blood gas interpretation
Answer: PaCO₂ = 32 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·16 + 8 = 32 mmHg
range: 30–34 mmHg
Answer
PaCO₂ = 32 mmHg
12.Arterial blood gas interpretation
Answer: PaCO₂ = 42 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·30 + 21 = 42 mmHg
Answer
PaCO₂ = 42 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: QTc = 0.458 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10.5 × 0.04 = 0.42 s
RR = 21 × 0.04 = 0.84 s
Bazett’s formula
QTc = 0.42/√0.84 = 0.42/0.9165 = 0.458 s
Answer
QTc = 0.458 s
Between the usual limits for men (about 0.45 s) and women (about 0.46 s): borderline, depending on the reference used. (458 ms)
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.16 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: B · Relieve pressure on the cord by lifting the presenting part with a gloved hand
Why this is the answer
In cord prolapse, the presenting part can compress the cord and cut off fetal oxygen. The nurse lifts the presenting part off the cord, calls for help and positions the patient (for example knee-chest) while urgent birth is arranged.
Answer
B · Relieve pressure on the cord by lifting the presenting part with a gloved hand
16.Prioritization & delegation
Answer: C · A patient who depends on a ventilator
Why this is the answer
A ventilator-dependent patient is at immediate risk. The nurse checks that the ventilator is on emergency power or battery and keeps a manual resuscitation bag ready.