Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has a prosthetic heart valve. Which teaching best reduces the risk of infective endocarditis?
AKeep teeth and gums healthy with regular dental check-ups
BAvoid eating dairy products and raw vegetables
CTake a daily antibiotic tablet indefinitely
DAvoid all physical exercise for the rest of their life
2.Med-surg: cardiovascular & respiratoryHard
After six weeks of treatment for tuberculosis, a patient has nausea, dark urine and yellow eyes. What should the nurse do?
AReassure the patient that the urine colour is due to rifampicin
BDouble the isoniazid dose to clear the infection faster
CWithhold the next doses and report urgently for liver tests
DAdvise taking the tablets with an alcoholic drink to settle the stomach
3.Med-surg: neuro, endocrine & renalMedium
A patient takes an SGLT2 inhibitor. Which sick-day advice is correct?
APause the drug during illness with vomiting or poor intake
BDouble the dose during illness to control the glucose
CStop drinking fluids while taking the drug
DKeep taking it as normal, whatever the illness
4.Med-surg: neuro, endocrine & renalHard
A patient with a known ureteric stone develops a fever of 39 °C (102.2 °F) and rigors. Scanning shows a blocked, swollen kidney. What is needed?
AStrong pain relief alone, then discharge
BA fluid restriction to reduce the swelling
CUrgent drainage of the kidney plus IV antibiotics
DOral antibiotics and waiting for the stone to pass
5.Med-surg: GI, perioperative & oncologyMedium
Which pain pattern classically suggests a duodenal rather than a gastric ulcer?
APain straight after eating that is worsened by food
BPain 2–3 hours after meals and at night, eased by eating
CPain only on deep breathing that eases when sitting forwards
DPain in the right lower abdomen with fever and vomiting
6.Med-surg: GI, perioperative & oncologyHard
A patient with lung cancer develops facial swelling, distended neck veins and breathlessness that worsens when lying down. Which emergency is likely?
ASuperior vena cava obstruction
BHypercalcaemia of malignancy
CSpinal cord compression
DMassive pulmonary embolism
7.Clinical nursingMedium
Which statement about storing insulin is correct?
AInsulin should be kept in direct sunlight
BAll insulin should be stored in the freezer to keep it fresh
CUnopened insulin is kept in the fridge and must not be frozen
DInsulin never expires once opened
8.Clinical nursingHard
A patient has a full-thickness burn all the way round the forearm. Which complication must be watched for closely?
ALoss of circulation to the hand as swelling builds under tight burned skin
BDelayed hair growth on the arm
CExcessive bleeding from the burn surface needing an urgent blood transfusion
DHypoglycaemia caused by the body using glucose to heal the burn
9.Lab values & electrolytesMedium
In countries that screen all pregnant women (such as the US), a vaginal-rectal swab is taken at about 36–37 weeks. Which organism is it screening for?
AGroup B Streptococcus
BCandida albicans
CHepatitis B virus
DStaphylococcus aureus
10.Lab values & electrolytesHard
A patient's low calcium does not improve despite several days of calcium replacement. Which other electrolyte should be checked and corrected?
ASodium
BBicarbonate
CChloride
DMagnesium
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 31 mmHg (4.1 kPa). Use the rule that in acute respiratory alkalosis HCO₃⁻ falls by 2 mmol/L for every 10 mmHg that PaCO₂ is below 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
At sea level, a practice gas taken on 40% oxygen shows PaO₂ 79 mmHg (10.5 kPa) and PaCO₂ 45 mmHg (6.0 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1normal sinus rhythm
2sinus arrhythmia
3second-degree AV block type II
4sinus rhythm with sinus arrest
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
Which SBAR recommendation is the clearest?
A“I just wanted to let you know about him.”
B“I will keep watching him and call again tomorrow.”
C“I would like you to see him within 15 minutes and consider a fluid bolus.”
D“He seems a bit off tonight, so maybe you could come up and do something about it.”
16.Prioritization & delegationHard
In a disaster with very limited resources, a victim with severe burns over almost the whole body is tagged black. Which principle explains this decision?
ATreating victims in the order in which they arrive
BDoing the greatest good for the greatest number
CTreating the youngest victims first
DTreating the most severely injured person first
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Keep teeth and gums healthy with regular dental check-ups
Why this is the answer
Oral bacteria often enter the blood and can settle on prosthetic valves. Good oral hygiene and regular dental care are key. Patients should also report unexplained fever and avoid body piercing or tattoos where possible. Antibiotic prophylaxis policies differ between countries.
Answer
A · Keep teeth and gums healthy with regular dental check-ups
2.Med-surg: cardiovascular & respiratory
Answer: C · Withhold the next doses and report urgently for liver tests
Why this is the answer
Isoniazid, rifampicin and pyrazinamide can all cause hepatotoxicity. Jaundice, dark urine and nausea suggest drug-induced hepatitis, so the drugs are stopped and liver function is checked urgently. Orange urine from rifampicin does not cause yellow eyes. Alcohol increases the risk.
Answer
C · Withhold the next doses and report urgently for liver tests
3.Med-surg: neuro, endocrine & renal
Answer: A · Pause the drug during illness with vomiting or poor intake
Why this is the answer
During dehydrating illness, SGLT2 inhibitors increase the risk of DKA, which can occur with only modestly raised glucose, and of acute kidney injury. Patients are taught to pause them until they are eating and drinking normally.
Answer
A · Pause the drug during illness with vomiting or poor intake
4.Med-surg: neuro, endocrine & renal
Answer: C · Urgent drainage of the kidney plus IV antibiotics
Why this is the answer
Infection behind an obstruction can quickly cause sepsis and kidney damage. Antibiotics alone will not clear it. The kidney needs urgent decompression, usually with a nephrostomy or ureteric stent.
Answer
C · Urgent drainage of the kidney plus IV antibiotics
5.Med-surg: GI, perioperative & oncology
Answer: B · Pain 2–3 hours after meals and at night, eased by eating
Why this is the answer
Classically, duodenal ulcer pain occurs when the stomach is empty and at night, and food or antacids ease it. Gastric ulcer pain is often brought on by eating. Patterns overlap, so endoscopy makes the diagnosis.
Answer
B · Pain 2–3 hours after meals and at night, eased by eating
6.Med-surg: GI, perioperative & oncology
Answer: A · Superior vena cava obstruction
Why this is the answer
A tumour can compress or invade the superior vena cava, causing facial and arm swelling, dilated chest veins, headache and breathlessness. The patient is sat up and urgently reviewed; treatment includes steroids, stenting and radiotherapy or chemotherapy.
Answer
A · Superior vena cava obstruction
7.Clinical nursing
Answer: C · Unopened insulin is kept in the fridge and must not be frozen
Why this is the answer
Unopened insulin is refrigerated; in-use pens or vials are usually kept at room temperature for a limited time stated by the manufacturer. Frozen or overheated insulin must be discarded.
Answer
C · Unopened insulin is kept in the fridge and must not be frozen
8.Clinical nursing
Answer: A · Loss of circulation to the hand as swelling builds under tight burned skin
Why this is the answer
Circumferential full-thickness burns form a tight eschar that acts like a tourniquet as oedema develops. Neurovascular checks are needed, and escharotomy may be required.
Answer
A · Loss of circulation to the hand as swelling builds under tight burned skin
9.Lab values & electrolytes
Answer: A · Group B Streptococcus
Why this is the answer
Group B streptococci can colonize the vagina and rectum and can cause severe infection in newborns. Women who test positive receive IV antibiotics during labor to reduce transmission to the baby. The UK does not screen all women routinely; it uses a risk-based approach instead.Checked against:Group B streptococcal septicemia of the newborn · MedlinePlus (NIH) (2024)
Answer
A · Group B Streptococcus
10.Lab values & electrolytes
Answer: D · Magnesium
Why this is the answer
Low magnesium reduces parathyroid hormone secretion and the body's response to it, so hypocalcemia does not correct until magnesium is replaced. The same applies to refractory hypokalemia.Checked against:Magnesium Blood Test · MedlinePlus (NIH) (2023)
Answer
D · Magnesium
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 22.2 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|31 − 40| = 9 mmHg → 0.9 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 − 2·0.9 = 22.2 mmol/L
Answer
HCO₃⁻ = 22.2 mmol/L
12.Arterial blood gas interpretation
Answer: A–a gradient = 149.9 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC. Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Five steps
1. Rate: 6 QRS complexes in 6 s, × 10 = 60 per minute.
2. Rhythm: regular (R–R 0.92 s) except for one pause of 1.48 s, which is not a whole number of P–P cycles.
3. P waves: upright, one before every QRS; no P wave at all during the pause.
4. PR interval: 0.16 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
sinus rhythm with sinus arrest
Answer
sinus rhythm with sinus arrest
14.ECG rhythm strip interpretation
Answer: rate
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 29 small boxes, 1500 ÷ 29 ≈ 52 per minute.
2. Rhythm: regular, every R–R is 1.16 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.16 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
First abnormal step
rate → sinus bradycardia
Answer
rate
15.Prioritization & delegation
Answer: C · “I would like you to see him within 15 minutes and consider a fluid bolus.”
Why this is the answer
A good recommendation is specific about the request and the time frame. Vague statements leave the provider unsure how urgent the problem is.
Answer
C · “I would like you to see him within 15 minutes and consider a fluid bolus.”
16.Prioritization & delegation
Answer: B · Doing the greatest good for the greatest number
Why this is the answer
In a mass-casualty event, resources are used where they save the most lives. A victim who is unlikely to survive even with full treatment is given comfort care, while staff treat salvageable victims. In everyday triage, the sickest patient is usually seen first.
Answer
B · Doing the greatest good for the greatest number