Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has just started an ACE inhibitor. Which blood tests are usually checked within the first one to two weeks?
AINR and platelet count
BTroponin and creatine kinase
CLiver enzymes and amylase
DPotassium and creatinine
2.Med-surg: cardiovascular & respiratoryHard
A patient on spironolactone and an ACE inhibitor has a potassium of 6.8 mmol/L (6.8 mEq/L) with peaked T waves. What is usually given first to protect the heart?
AA dose of digoxin
BOral potassium supplements
CAn IV furosemide bolus as the only treatment
DIntravenous calcium gluconate or chloride
3.Med-surg: neuro, endocrine & renalMedium
A patient with type 1 diabetes has gastroenteritis and cannot eat. Which sick-day advice is correct?
AStop all insulin until normal eating restarts
BAvoid drinking fluids to reduce the vomiting
CKeep taking basal insulin and check glucose and ketones more often
DCheck glucose once a day only and rest in bed until better
4.Med-surg: neuro, endocrine & renalHard
A patient in thyroid storm has a temperature of 40 °C (104 °F). Which measure for the fever is usually avoided?
AFanning with cool air
BAspirin
CParacetamol (acetaminophen)
DCooling blankets
5.Med-surg: GI, perioperative & oncologyMedium
Why are superficial burns (redness only, like sunburn) not counted when calculating burn area for fluid resuscitation?
AThey always heal completely within one day
BThey are always too small to measure accurately on a chart
CThe skin barrier is intact, so little fluid is lost
DThey cause more fluid loss than any other depth
6.Med-surg: GI, perioperative & oncologyHard
Which new prescription for a patient with cirrhosis should the nurse question?
ASpironolactone for ascites
BThiamine supplements
CLactulose to keep the bowels open
DRegular ibuprofen for back pain
7.Clinical nursingMedium
A patient's abdomen is rigid and board-like, and they lie very still because movement worsens the pain. What does this suggest?
AIndigestion
BUrinary tract infection
CConstipation
DPeritonitis
8.Clinical nursingHard
Why might a patient with diabetes who takes a beta-blocker not notice hypoglycaemia early?
ABeta-blockers stop the liver from responding to insulin
BBeta-blockers make the patient sleep through the night
CBeta-blockers can mask warning signs such as tremor and a fast heart rate
DBeta-blockers raise blood glucose, so true hypoglycaemia cannot happen at all
9.Lab values & electrolytesMedium
When should a blood sample for a digoxin level be drawn to be interpreted correctly?
AAt least 6–8 hours after a dose, often just before the next one
BAt any time, because digoxin levels do not change during the day
COnly after a meal, because food is needed for absorption
DWithin 30 minutes after an oral dose to show the peak level
10.Lab values & electrolytesHard
A patient on a stable dose of levothyroxine now has a TSH of 9.8 mIU/L. She recently started taking her calcium and iron supplements with her morning levothyroxine. What is the most likely explanation?
AThe TSH is low, showing that the dose is now too high
BThe result is normal for a person on levothyroxine therapy
CThe supplements are reducing levothyroxine absorption
DThe supplements are causing an overactive thyroid gland
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.53, PaCO₂ 20 mmHg (2.7 kPa) and HCO₃⁻ 16 mmol/L. The primary disorder is respiratory alkalosis. How far is it compensated? Click your answer.
pH 7.53PaCO₂ 20 mmHg (2.7 kPa)HCO₃⁻ 16 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 134, Cl⁻ 109, HCO₃⁻ 11 mmol/L and albumin 30 g/L. Find the albumin-corrected anion gap AGc = AG + 0.25·(40 − albumin).
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1ventricular tachycardia
2sinus bradycardia
3idioventricular rhythm
4third-degree (complete) AV block
15.Prioritization & delegationMedium
During START triage, a non-walking adult breathes 22 times a minute, has a radial pulse and follows simple commands, but has an obvious leg fracture. Which category is the victim given?
ARed (immediate)
BGreen (minor)
CBlack (expectant)
DYellow (delayed)
16.Prioritization & delegationHard
A patient with known abdominal aortic aneurysm suddenly has severe back pain, a pulsing mass in the abdomen and a falling blood pressure. What should the nurse do?
AGive an oral analgesic and reassess the patient in about one hour
BCall for emergency help at once and prepare for urgent surgery
CEncourage the patient to walk to ease the back pain
DPalpate the mass firmly to check its size and spread
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · Potassium and creatinine
Why this is the answer
ACE inhibitors lower aldosterone, so potassium can rise, and they reduce glomerular filtration pressure, so creatinine can rise, especially with renal artery stenosis or dehydration. Baseline and early follow-up urea, electrolytes and creatinine are standard.
Answer
D · Potassium and creatinine
2.Med-surg: cardiovascular & respiratory
Answer: D · Intravenous calcium gluconate or chloride
Why this is the answer
Severe hyperkalaemia with ECG changes is an emergency. IV calcium stabilises the myocardium within minutes. Insulin with glucose and nebulised salbutamol shift potassium into cells, and the cause (here spironolactone and the ACE inhibitor) is stopped. Cardiac monitoring is essential.
Answer
D · Intravenous calcium gluconate or chloride
3.Med-surg: neuro, endocrine & renal
Answer: C · Keep taking basal insulin and check glucose and ketones more often
Why this is the answer
Stress hormones during illness raise glucose and ketones. Stopping insulin can quickly lead to DKA. Patients keep taking basal insulin, test glucose and ketones often, drink fluids and seek help if ketones rise or vomiting persists.
Answer
C · Keep taking basal insulin and check glucose and ketones more often
4.Med-surg: neuro, endocrine & renal
Answer: B · Aspirin
Why this is the answer
Aspirin (salicylates) displaces thyroid hormone from binding proteins, raising free hormone levels. Paracetamol (acetaminophen) and external cooling are used instead, together with treatment for the storm itself.
Answer
B · Aspirin
5.Med-surg: GI, perioperative & oncology
Answer: C · The skin barrier is intact, so little fluid is lost
Why this is the answer
Superficial (epidermal) burns cause pain and redness but not the capillary leak and fluid loss of partial- and full-thickness burns. Including them overestimates the burn size and leads to excess fluid.
Answer
C · The skin barrier is intact, so little fluid is lost
6.Med-surg: GI, perioperative & oncology
Answer: D · Regular ibuprofen for back pain
Why this is the answer
NSAIDs can cause kidney injury, fluid retention and GI bleeding in cirrhosis and should be avoided. Paracetamol at a reduced, carefully reviewed dose is usually preferred for pain.
Answer
D · Regular ibuprofen for back pain
7.Clinical nursing
Answer: D · Peritonitis
Why this is the answer
Peritonitis, often from perforation, causes guarding, rigidity and pain worsened by movement. It is a surgical emergency.
Answer
D · Peritonitis
8.Clinical nursing
Answer: C · Beta-blockers can mask warning signs such as tremor and a fast heart rate
Why this is the answer
Tremor, palpitations and anxiety in hypoglycaemia are driven by the sympathetic system, which beta-blockers blunt. Sweating is often still present, and patients need to monitor glucose closely.
Answer
C · Beta-blockers can mask warning signs such as tremor and a fast heart rate
9.Lab values & electrolytes
Answer: A · At least 6–8 hours after a dose, often just before the next one
Why this is the answer
Digoxin distributes slowly from blood to tissues, so a sample taken too soon after a dose is falsely high. Levels are drawn at least 6–8 hours after a dose, commonly as a trough before the next dose.
Answer
A · At least 6–8 hours after a dose, often just before the next one
10.Lab values & electrolytes
Answer: C · The supplements are reducing levothyroxine absorption
Why this is the answer
Calcium, iron and antacids bind levothyroxine in the gut and reduce absorption, so the TSH rises. Levothyroxine is taken on an empty stomach, usually 30–60 minutes before breakfast, separated from these supplements by about 4 hours.
Answer
C · The supplements are reducing levothyroxine absorption
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.53: alkalaemia (above 7.45)
PaCO₂ 20 mmHg: low (35–45)
HCO₃⁻ 16 mmol/L: low (22–26)
Compensation
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: AGc = 16.5 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 134 − (109 + 11) = 14
Correction for albumin
14 + 0.25·(40 − 30) = 16.5 mmol/L
Answer
AGc = 16.5 mmol/L
Above about 12 after correction: a high anion gap.
13.ECG rhythm strip interpretation
Answer: QTc = 0.482 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10.5 × 0.04 = 0.42 s
RR = 19 × 0.04 = 0.76 s
Bazett’s formula
QTc = 0.42/√0.76 = 0.42/0.8718 = 0.482 s
Answer
QTc = 0.482 s
Above the usual limits for both men (about 0.45 s) and women (about 0.46 s): prolonged. (482 ms)
14.ECG rhythm strip interpretation
Answer: idioventricular rhythm
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: R–R = 47 small boxes, 1500 ÷ 47 ≈ 32 per minute.
2. Rhythm: regular, every R–R is 1.88 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.18 s, wide (0.12 s or more) and bizarre, with the T wave pointing the other way.
Interpretation
idioventricular rhythm
Answer
idioventricular rhythm
An idioventricular rhythm is an escape rhythm: the ventricles take over because the pacemakers above them have failed.
15.Prioritization & delegation
Answer: D · Yellow (delayed)
Why this is the answer
A victim who cannot walk but passes the breathing, perfusion and mental status checks is delayed (yellow). A serious injury alone does not make a victim immediate.
Answer
D · Yellow (delayed)
16.Prioritization & delegation
Answer: B · Call for emergency help at once and prepare for urgent surgery
Why this is the answer
Sudden severe back or abdominal pain with hypotension in a patient with an aneurysm suggests rupture, which is fatal without urgent surgery. The mass should not be palpated firmly.
Answer
B · Call for emergency help at once and prepare for urgent surgery