Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
When should an adult with cystic fibrosis take pancreatic enzyme capsules?
AOnly at bedtime
BWith all meals and snacks that contain fat
COnce a day on waking, at least an hour before any food
DOnly when they have diarrhoea
2.Med-surg: cardiovascular & respiratoryHard
A patient on warfarin for atrial fibrillation has an INR of 8.5 but no bleeding. What is the most likely management?
AWithhold warfarin, inform the prescriber and recheck the INR soon
BContinue the usual dose and recheck the INR in a month
CGive prothrombin complex concentrate and a blood transfusion
DGive IV protamine sulfate immediately to reverse it
3.Med-surg: neuro, endocrine & renalMedium
Why are insulin and glucose given together to treat hyperkalaemia?
AInsulin moves potassium into cells; glucose prevents a hypo
BGlucose binds the potassium in the blood and removes it
CInsulin protects the heart muscle cells from the potassium
DInsulin makes the kidneys pass more potassium in the urine
4.Med-surg: neuro, endocrine & renalHard
Near the end of a haemodialysis session, a patient has painful leg cramps and a falling blood pressure. What is the most likely cause?
AFluid is being removed too quickly
BThe dialysate is too cold
CAn allergic reaction to the needles
DNot enough fluid is being removed
5.Med-surg: GI, perioperative & oncologyMedium
A patient had an upper GI endoscopy with a local anaesthetic throat spray. What must the nurse check before giving a drink?
AThat the patient has passed urine since the procedure
BThat the patient's blood glucose is above normal
CThat bowel sounds are present in all four quadrants
DThat swallowing and the gag reflex have returned
6.Med-surg: GI, perioperative & oncologyHard
A patient taking IV antibiotics has three unexplained loose stools in 24 hours. What should the nurse do first?
AWait two days to see if the diarrhoea settles
BIsolate the patient and send a stool sample for testing
CMove the patient to a bay with other patients to watch them closely
DGive loperamide after each loose stool and continue as usual
7.Clinical nursingMedium
Under the Mental Capacity Act 2005 (England and Wales), which principle applies?
AA person must be assumed to have capacity unless it is shown that they lack it
BEveryone over 75 is assumed to lack capacity
CCapacity is decided by the next of kin, who must sign a form for every decision
DA diagnosis of dementia means the person lacks capacity for all decisions
8.Clinical nursingHard
A patient has sudden, severe "tearing" chest pain going through to the back and a large difference in blood pressure between the arms. What should be suspected?
AStable angina
BAortic dissection
CPericarditis
DGastro-oesophageal reflux
9.Lab values & electrolytesMedium
During a red cell transfusion, when are serious acute reactions most likely, so the nurse stays with the patient?
AThe next morning
BIn the first 15 minutes
CAfter the last drop is given
DAfter about 2 hours
10.Lab values & electrolytesHard
A patient with a calcium of 6.8 mg/dL (1.7 mmol/L) suddenly develops noisy breathing and a hoarse voice. What does this suggest?
AA normal response that will pass without treatment
BA common cold that started this morning
CLaryngospasm, an emergency needing urgent help and IV calcium
DAnxiety about the blood results, which needs calm reassurance
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 146 mmol/L, glucose 12 mmol/L and urea 8 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 146 mmol/Lglucose 12 mmol/Lurea 8 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 139, Cl⁻ 98 and HCO₃⁻ 14 mmol/L. Calculate the delta ratio (AG − 12)/(24 − HCO₃⁻), using AG = Na⁺ − (Cl⁻ + HCO₃⁻). Give two decimals.
Na⁺ 139 mmol/LCl⁻ 98 mmol/LHCO₃⁻ 14 mmol/L
delta ratio =
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1sinus bradycardia
2sinus tachycardia
3junctional rhythm
4normal sinus rhythm
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type II
2sinus bradycardia
3first-degree AV block
4third-degree (complete) AV block
15.Prioritization & delegationMedium
A nursing assistant offers to suction a patient’s new tracheostomy. Which response from the RN is best?
A“Leave the suctioning until the next shift arrives.”
B“Thank you, please suction him as needed and tell me how it went.”
C“Suctioning a new tracheostomy is my task; I will do it myself.”
D“Ask the patient’s family to do the suctioning today.”
16.Prioritization & delegationHard
A patient with a new tracheostomy is coughing, has noisy breathing and an SpO₂ that has fallen to 86%. What is the first action?
AChange the tracheostomy ties
BGive a nebulized bronchodilator
CSuction the tracheostomy
DDocument the SpO₂ and recheck in 30 minutes
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · With all meals and snacks that contain fat
Why this is the answer
In CF, thick secretions block the pancreatic ducts, causing fat malabsorption and fatty stools. Enzyme capsules are taken with every meal and fat-containing snack, with the dose adjusted to fat intake. Fat-soluble vitamins (A, D, E, K) are also supplemented.
Answer
B · With all meals and snacks that contain fat
2.Med-surg: cardiovascular & respiratory
Answer: A · Withhold warfarin, inform the prescriber and recheck the INR soon
Why this is the answer
A very high INR without bleeding is usually managed by withholding warfarin, informing the prescriber and repeating the INR. Low-dose oral vitamin K may also be prescribed depending on the INR and local protocol (UK guidance gives it above an INR of 8; US guidance mainly above 10 or with high bleeding risk). Prothrombin complex concentrate and IV vitamin K are used for major bleeding. Protamine reverses heparin. The reason for the rise (new drugs, illness, diet) should be explored.
Answer
A · Withhold warfarin, inform the prescriber and recheck the INR soon
3.Med-surg: neuro, endocrine & renal
Answer: A · Insulin moves potassium into cells; glucose prevents a hypo
Why this is the answer
Insulin activates the sodium–potassium pump, moving potassium into cells and lowering the serum level within about 15–30 minutes. Glucose is given to prevent hypoglycaemia. The effect is temporary, so potassium must also be removed.
Answer
A · Insulin moves potassium into cells; glucose prevents a hypo
4.Med-surg: neuro, endocrine & renal
Answer: A · Fluid is being removed too quickly
Why this is the answer
Muscle cramps and hypotension during dialysis are often due to rapid or excessive fluid removal. Staff may reduce the ultrafiltration rate and give saline per protocol. The dry weight may need to be reviewed.
Answer
A · Fluid is being removed too quickly
5.Med-surg: GI, perioperative & oncology
Answer: D · That swallowing and the gag reflex have returned
Why this is the answer
Throat spray numbs the pharynx, so drinking too early risks aspiration. Fluids are given once the gag reflex and swallowing have returned, usually after about an hour, starting with sips of water.
Answer
D · That swallowing and the gag reflex have returned
6.Med-surg: GI, perioperative & oncology
Answer: B · Isolate the patient and send a stool sample for testing
Why this is the answer
Unexplained diarrhoea in a patient on antibiotics should be treated as possible C. difficile. The patient is isolated promptly, a stool sample is sent and the antibiotics are reviewed with the medical team.
Answer
B · Isolate the patient and send a stool sample for testing
7.Clinical nursing
Answer: A · A person must be assumed to have capacity unless it is shown that they lack it
Why this is the answer
The Act begins by presuming capacity. Capacity is decision-specific and time-specific, and people must be given all practicable help to make their own decision.
Answer
A · A person must be assumed to have capacity unless it is shown that they lack it
8.Clinical nursing
Answer: B · Aortic dissection
Why this is the answer
Aortic dissection classically causes abrupt, tearing pain radiating to the back, with unequal arm pulses or pressures. It is a surgical emergency, and thrombolysis must not be given.
Answer
B · Aortic dissection
9.Lab values & electrolytes
Answer: B · In the first 15 minutes
Why this is the answer
Acute hemolytic and anaphylactic reactions usually appear early, so the transfusion is started slowly and the nurse stays with the patient for about the first 15 minutes, checking vital signs before, during and after according to policy.
Answer
B · In the first 15 minutes
10.Lab values & electrolytes
Answer: C · Laryngospasm, an emergency needing urgent help and IV calcium
Why this is the answer
Severe hypocalcemia can cause spasm of the larynx, which blocks the airway. The nurse calls for urgent help, supports the airway and prepares IV calcium gluconate as prescribed, with cardiac monitoring.Checked against:Hypocalcemia (StatPearls) · StatPearls (NCBI Bookshelf) (2026)
Answer
C · Laryngospasm, an emergency needing urgent help and IV calcium
11.Arterial blood gas interpretation
Answer: Osm = 312 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·146 + 12 + 8 = 312 ≈ 312 mOsm/kg
Answer
Osm = 312 mOsm/kg
12.Arterial blood gas interpretation
Answer: delta ratio = 1.5
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 139 − (98 + 14) = 27
Delta ratio
(27 − 12)/(24 − 14) = 15/10 = 1.5
Answer
delta ratio = 1.5
Between 1 and 2: a pure high anion gap acidosis.
13.ECG rhythm strip interpretation
Answer: sinus bradycardia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 32 small boxes, 1500 ÷ 32 ≈ 47 per minute.
2. Rhythm: regular, every R–R is 1.28 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
sinus bradycardia
Answer
sinus bradycardia
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 6 QRS complexes in 6 s, × 10 = 60 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.72 s, 83 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: C · “Suctioning a new tracheostomy is my task; I will do it myself.”
Why this is the answer
Care of a new tracheostomy, including suctioning, involves airway risk and assessment, so the RN keeps it. Leaving it to the family or the next shift is unsafe.
Answer
C · “Suctioning a new tracheostomy is my task; I will do it myself.”
16.Prioritization & delegation
Answer: C · Suction the tracheostomy
Why this is the answer
Noisy breathing, coughing and a falling SpO₂ in a patient with a tracheostomy suggest secretions in the tube. Suctioning clears the airway. If the airway is still blocked, follow the emergency tracheostomy algorithm and call for help.