Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
How is orthostatic (postural) hypotension usually assessed?
ABP lying after rest, then again after 1 and 3 minutes standing
BBP in both arms at the same moment while sitting
CBP only standing, after a brisk walk along the corridor
DBP once sitting, then once lying down straight after a large meal
2.Med-surg: cardiovascular & respiratoryHard
A patient with infective endocarditis is on IV gentamicin with another antibiotic. Which monitoring is most important?
APeak flow readings and spirometry before and after each dose
BBlood glucose only
CDrug levels, renal function and hearing or balance changes
DLiver size by daily palpation and weekly abdominal ultrasound
3.Med-surg: neuro, endocrine & renalMedium
Why is nimodipine given to patients after a subarachnoid haemorrhage?
ATo dissolve the blood clot around the aneurysm
BTo reduce brain injury from delayed vasospasm
CTo raise the blood pressure and improve perfusion
DTo stop seizures in the first few days
4.Med-surg: neuro, endocrine & renalHard
Two days after an ileal conduit was formed, the stoma is dark purple and dry. What should the nurse do?
ARecord it as normal for a new stoma
BApply a warm compress to improve the colour of the stoma
CReport it urgently, because the stoma may be ischaemic
DChange the bag and check again next week
5.Med-surg: GI, perioperative & oncologyMedium
How is an uncomplicated sigmoid volvulus often first treated?
AEating a large high-fibre meal
BA barium meal given by mouth to untwist the bowel slowly
CDecompression with a flexible sigmoidoscope and flatus tube
DHigh-dose laxatives taken by mouth
6.Med-surg: GI, perioperative & oncologyHard
A few hours after an ERCP, a patient has severe epigastric pain radiating to the back, with vomiting. Which complication is most likely?
AAcute appendicitis
BBiliary colic from a new stone
CPost-ERCP pancreatitis
DHepatitis B infection
7.Clinical nursingMedium
Why does a patient with a suspected TIA need urgent specialist assessment?
AThe patient needs urgent surgery on the brain
BThe risk of a full stroke is highest in the days after a TIA
CThe symptoms will come back permanently within an hour
DA TIA always turns into a brain tumour unless it is treated
8.Clinical nursingHard
A patient on enteral tube feeding after a long period of starvation develops low phosphate, low potassium and arrhythmias. What is most likely?
ADumping syndrome
BHyperthyroidism
CRefeeding syndrome
DDiabetic ketoacidosis
9.Lab values & electrolytesMedium
Which instruction is correct for a patient starting oral iron tablets?
ATake each tablet with milk to protect the stomach
BYour stools may turn dark green or black
CYour urine will turn bright orange while you take it
DTake the tablet with an antacid to improve absorption
10.Lab values & electrolytesHard
A patient with heart failure takes lisinopril, spironolactone and a potassium supplement. Today the potassium is 6.0 mEq/L. What is the most likely explanation?
ALisinopril lowers potassium
BSeveral medicines that raise potassium are being taken together
CPotassium supplements have no effect on the serum level
DSpironolactone causes potassium loss
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.50, PaCO₂ 50 mmHg (6.7 kPa) and HCO₃⁻ 38 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.50PaCO₂ 50 mmHg (6.7 kPa)HCO₃⁻ 38 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.16, PaCO₂ 81 mmHg (10.8 kPa), HCO₃⁻ 28 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.16PaCO₂ 81 mmHg (10.8 kPa)HCO₃⁻ 28 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial flutter, 4:1 conduction
2ventricular fibrillation
3atrial fibrillation
4asystole
15.Prioritization & delegationMedium
A patient has a blood pressure of 210/120 mmHg. Which finding would make this a hypertensive emergency?
AForgetting to take the blood pressure tablet this morning
BA history of high blood pressure for ten years
CNew chest pain or confusion suggesting organ damage
DMild anxiety about the high reading on the monitor
16.Prioritization & delegationHard
A patient opens their eyes only to pain, uses inappropriate words and withdraws from pain. What is the Glasgow Coma Scale score?
A13
B7
C11
D9
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · BP lying after rest, then again after 1 and 3 minutes standing
Why this is the answer
Blood pressure is measured after the patient has been lying for about 5 minutes, then after 1 and 3 minutes of standing. A fall in systolic pressure of 20 mmHg or more, or diastolic of 10 mmHg or more, indicates orthostatic hypotension. Symptoms such as dizziness are recorded too.
Answer
A · BP lying after rest, then again after 1 and 3 minutes standing
2.Med-surg: cardiovascular & respiratory
Answer: C · Drug levels, renal function and hearing or balance changes
Why this is the answer
Gentamicin is nephrotoxic and ototoxic. Levels are measured to guide dosing, renal function is checked regularly and patients are asked about tinnitus, hearing loss and dizziness. Risk is greater with loop diuretics, older age and longer courses.
Answer
C · Drug levels, renal function and hearing or balance changes
3.Med-surg: neuro, endocrine & renal
Answer: B · To reduce brain injury from delayed vasospasm
Why this is the answer
Nimodipine, a calcium channel blocker, reduces the risk of poor outcome from delayed cerebral ischaemia caused by vasospasm. Blood pressure must be monitored because it can cause hypotension.
Answer
B · To reduce brain injury from delayed vasospasm
4.Med-surg: neuro, endocrine & renal
Answer: C · Report it urgently, because the stoma may be ischaemic
Why this is the answer
A dusky, purple or black stoma suggests poor blood supply and possible necrosis. It needs urgent surgical review. A healthy stoma is moist and pink to red, and some swelling is normal at first.
Answer
C · Report it urgently, because the stoma may be ischaemic
5.Med-surg: GI, perioperative & oncology
Answer: C · Decompression with a flexible sigmoidoscope and flatus tube
Why this is the answer
Endoscopic decompression often untwists a sigmoid volvulus. Recurrence is common, so elective surgery may follow. Signs of ischaemia or perforation need emergency surgery.
Answer
C · Decompression with a flexible sigmoidoscope and flatus tube
6.Med-surg: GI, perioperative & oncology
Answer: C · Post-ERCP pancreatitis
Why this is the answer
Pancreatitis is the most common serious complication of ERCP. Severe epigastric pain radiating to the back with raised amylase or lipase suggests it; management includes analgesia, IV fluids and close monitoring.
Answer
C · Post-ERCP pancreatitis
7.Clinical nursing
Answer: B · The risk of a full stroke is highest in the days after a TIA
Why this is the answer
The risk of stroke is highest soon after a TIA. Rapid assessment and treatment, such as antiplatelets, statins and carotid imaging, reduce this risk.
Answer
B · The risk of a full stroke is highest in the days after a TIA
8.Clinical nursing
Answer: C · Refeeding syndrome
Why this is the answer
Refeeding syndrome results from rapid shifts of phosphate, potassium and magnesium into cells when feeding resumes. High-risk patients start slowly with electrolyte monitoring and thiamine.
Answer
C · Refeeding syndrome
9.Lab values & electrolytes
Answer: B · Your stools may turn dark green or black
Why this is the answer
Oral iron commonly darkens the stools, which is harmless, but black tarry stools with abdominal pain should be reported. Milk, antacids and tea reduce absorption; vitamin C or orange juice can improve it.Checked against:Ferrograd C patient information leaflet (ferrous sulfate + vitamin C) · electronic medicines compendium (eMC), UK (2018)
Answer
B · Your stools may turn dark green or black
10.Lab values & electrolytes
Answer: B · Several medicines that raise potassium are being taken together
Why this is the answer
ACE inhibitors and spironolactone both make the kidneys retain potassium, and a supplement adds more. The nurse holds the supplement, informs the prescriber and checks kidney function and the ECG.Checked against:High potassium level · MedlinePlus (NIH) (2025); Spironolactone · MedlinePlus (NIH) (2018)
Answer
B · Several medicines that raise potassium are being taken together
11.Arterial blood gas interpretation
Answer: partially compensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.50: alkalaemia (above 7.45)
PaCO₂ 50 mmHg: high (35–45)
HCO₃⁻ 38 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 45.6–49.6 mmHg, so the measured 50 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
partially compensated
Answer
partially compensated
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·4.1 = 28.1 mmol/L
chronic: 24 + 3.5·4.1 = 38.35 mmol/L
Compare
measured: 28 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: QTc = 0.38 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 9.5 × 0.04 = 0.38 s
RR = 25 × 0.04 = 1.00 s
Fridericia’s formula
QTc = 0.38/∛1.00 = 0.38/1 = 0.38 s
Answer
QTc = 0.38 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (380 ms)
14.ECG rhythm strip interpretation
Answer: ventricular fibrillation
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: chaotic, no repeating pattern.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
ventricular fibrillation
Answer
ventricular fibrillation
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: C · New chest pain or confusion suggesting organ damage
Why this is the answer
Severe hypertension becomes an emergency when there is acute organ damage, such as chest pain, neurological changes or kidney injury. It needs urgent, controlled lowering of the blood pressure.
Answer
C · New chest pain or confusion suggesting organ damage
16.Prioritization & delegation
Answer: D · 9
Why this is the answer
Eyes open to pain scores 2, inappropriate words score 3 and withdrawal from pain scores 4, giving 9. A score of 8 or less often means the patient cannot protect their airway.