Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
After an arterial blood gas sample is taken from the radial artery, what should the nurse do?
AApply firm pressure to the site for several minutes
BBend the wrist sharply upwards to stop the bleeding
CLeave the site uncovered without pressure
DMassage the site to help the bruising fade
2.Med-surg: cardiovascular & respiratoryHard
A patient with known peripheral arterial disease suddenly has a cold, white, painful foot with no pulses and numb toes. What is the priority?
AEscalate at once as an emergency; keep the leg level, no heat
BApply a compression bandage to improve the circulation
CEncourage walking to open up the collateral circulation
DRaise the leg on pillows and warm the foot with a hot water bottle
3.Med-surg: neuro, endocrine & renalMedium
What is the dexamethasone suppression test used for?
ATo diagnose diabetes insipidus
BTo measure kidney function
CTo help diagnose Cushing's syndrome
DTo check thyroid function
4.Med-surg: neuro, endocrine & renalHard
Which task can the registered nurse delegate to a trained healthcare assistant (nursing assistant)?
ADeciding the dose of correction insulin from the glucose result
BTeaching a new patient how to inject insulin
CAssessing a confused patient whose glucose is 2.6 mmol/L (47 mg/dL)
DChecking pre-meal glucose and reporting results out of range
5.Med-surg: GI, perioperative & oncologyMedium
Which statement about corticosteroids in inflammatory bowel disease is correct?
AThey are given only as a one-off injection
BThey cure the disease after one course
CThey are the best long-term maintenance treatment
DThey are used to induce remission, not for maintenance
6.Med-surg: GI, perioperative & oncologyHard
A 60 kg adult with 25% TBSA burns arrives 2 hours after the injury, having had no IV fluids. Using the Parkland formula, what hourly rate is needed for the rest of the first 8 hours?
A500 mL/h
B375 mL/h
C250 mL/h
D1000 mL/h
7.Clinical nursingMedium
A patient without diabetes is started on high-dose prednisolone. Why might capillary blood glucose be monitored?
ASteroids make glucose meters inaccurate
BSteroids destroy the pancreas
CSteroids can raise the blood glucose
DSteroids always cause hypoglycaemia
8.Clinical nursingHard
The fluid in an underwater seal chest drain has stopped swinging with breathing. What could this mean?
AThe tube may be kinked or blocked, or the lung may have fully re-expanded
BThe water seal has been set up correctly for the first time
CThe drain is working perfectly and needs no checks
DThe patient's breathing has become normal and the drain can be pulled out by the nurse
9.Lab values & electrolytesMedium
Which instruction is correct for a patient starting oral iron tablets?
ATake each tablet with milk to protect the stomach
BYour stools may turn dark green or black
CYour urine will turn bright orange while you take it
DTake the tablet with an antacid to improve absorption
10.Lab values & electrolytesHard
The nurse teaches a patient with thrombocytopenia (platelets 25 × 10³/µL) about home safety. Which statement shows a need for further teaching?
A"I'll take aspirin if I get a headache"
B"I'll use a soft-bristled toothbrush"
C"I'll blow my nose gently, not forcefully"
D"I'll use an electric razor to shave"
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 6 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 6 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
Practice values: Na⁺ 143, Cl⁻ 98 and HCO₃⁻ 13 mmol/L. Calculate the delta ratio (AG − 12)/(24 − HCO₃⁻), using AG = Na⁺ − (Cl⁻ + HCO₃⁻). Give two decimals.
Na⁺ 143 mmol/LCl⁻ 98 mmol/LHCO₃⁻ 13 mmol/L
delta ratio =
13.ECG rhythm strip interpretationMedium
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2first-degree AV block
3second-degree AV block type I (Wenckebach)
4second-degree AV block type II
15.Prioritization & delegationMedium
A nurse takes a telephone order from a provider. What must the nurse do?
ARemember the order and write it in the chart at the end of the shift
BAsk the ward clerk to take the order on the nurse’s behalf instead
CWrite the order down and read it back to the provider to confirm it
DCarry out the order first and ask the provider to confirm it later
16.Prioritization & delegationHard
A patient receiving comfort-focused end-of-life care is distressed by breathlessness. Which approach is most appropriate?
AWithhold all opioids because they may slow breathing
BLeave the patient alone so they can rest
CStart a series of aggressive tests to find the exact cause of the breathlessness
DGive prescribed opioids and use positioning and a fan to relieve breathlessness
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Apply firm pressure to the site for several minutes
Why this is the answer
Firm pressure for at least about 5 minutes (longer in patients on anticoagulants or with clotting problems) prevents a haematoma. The hand is checked for colour and circulation. The sample is processed promptly.
Answer
A · Apply firm pressure to the site for several minutes
2.Med-surg: cardiovascular & respiratory
Answer: A · Escalate at once as an emergency; keep the leg level, no heat
Why this is the answer
Pain, pallor, pulselessness, paraesthesia, paralysis and a perishingly cold limb indicate acute limb ischaemia, usually from an embolus or thrombosis. Revascularisation within hours is needed to save the limb. Heat increases metabolic demand and can burn, elevation reduces arterial flow and compression is harmful.
Answer
A · Escalate at once as an emergency; keep the leg level, no heat
3.Med-surg: neuro, endocrine & renal
Answer: C · To help diagnose Cushing's syndrome
Why this is the answer
A dose of dexamethasone normally suppresses ACTH and cortisol. In Cushing's syndrome, cortisol stays high. The test is part of the work-up for cortisol excess.
Answer
C · To help diagnose Cushing's syndrome
4.Med-surg: neuro, endocrine & renal
Answer: D · Checking pre-meal glucose and reporting results out of range
Why this is the answer
Trained assistants can measure and record glucose and report abnormal results. Dose decisions, teaching and the assessment of an unstable patient need the registered nurse.
Answer
D · Checking pre-meal glucose and reporting results out of range
5.Med-surg: GI, perioperative & oncology
Answer: D · They are used to induce remission, not for maintenance
Why this is the answer
Steroids settle flares but are not effective or safe for maintenance because of side effects such as osteoporosis, diabetes and infection. Drugs such as aminosalicylates, immunomodulators or biologics maintain remission.
Answer
D · They are used to induce remission, not for maintenance
6.Med-surg: GI, perioperative & oncology
Answer: A · 500 mL/h
Why this is the answer
Parkland gives 4 × 60 × 25 = 6000 mL in 24 hours, with 3000 mL due in the first 8 hours from the time of injury. With 6 hours left, 3000 ÷ 6 = 500 mL/h. Dividing by 8 (375 mL/h) ignores the delay. The rate is then adjusted to urine output.
Answer
A · 500 mL/h
7.Clinical nursing
Answer: C · Steroids can raise the blood glucose
Why this is the answer
Glucocorticoids increase glucose production and insulin resistance, causing steroid-induced hyperglycaemia. Glucose monitoring identifies patients who need treatment.
Answer
C · Steroids can raise the blood glucose
8.Clinical nursing
Answer: A · The tube may be kinked or blocked, or the lung may have fully re-expanded
Why this is the answer
Loss of swing can mean a kinked, clamped or blocked tube, or re-expansion of the lung. The nurse checks the tubing and the patient and reports the finding.
Answer
A · The tube may be kinked or blocked, or the lung may have fully re-expanded
9.Lab values & electrolytes
Answer: B · Your stools may turn dark green or black
Why this is the answer
Oral iron commonly darkens the stools, which is harmless, but black tarry stools with abdominal pain should be reported. Milk, antacids and tea reduce absorption; vitamin C or orange juice can improve it.Checked against:Ferrograd C patient information leaflet (ferrous sulfate + vitamin C) · electronic medicines compendium (eMC), UK (2018)
Answer
B · Your stools may turn dark green or black
10.Lab values & electrolytes
Answer: A · "I'll take aspirin if I get a headache"
Why this is the answer
Aspirin irreversibly inhibits platelet function and raises the bleeding risk further in thrombocytopenia, so it and other NSAIDs are avoided unless prescribed. An electric razor, gentle nose blowing and a soft toothbrush reduce minor bleeding.Checked against:Bleeding and Bruising (Thrombocytopenia) and Cancer Treatment · National Cancer Institute (NIH) (2022); Aspirin · MedlinePlus (NIH) (2025)
Answer
A · "I'll take aspirin if I get a headache"
11.Arterial blood gas interpretation
Answer: PaCO₂ = 17 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·6 + 8 = 17 mmHg
range: 15–19 mmHg
Answer
PaCO₂ = 17 mmHg
12.Arterial blood gas interpretation
Answer: delta ratio = 1.818
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 143 − (98 + 13) = 32
Delta ratio
(32 − 12)/(24 − 13) = 20/11 = 1.818
Answer
delta ratio = 1.818
Between 1 and 2: a pure high anion gap acidosis.
13.ECG rhythm strip interpretation
Answer: QTc = 0.447 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 20 × 0.04 = 0.80 s
Bazett’s formula
QTc = 0.40/√0.80 = 0.40/0.8944 = 0.447 s
Answer
QTc = 0.447 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (447 ms)
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 0.88 s, 68 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: lengthens 0.16 → 0.28 → 0.36 s, then a P wave is not conducted.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: C · Write the order down and read it back to the provider to confirm it
Why this is the answer
For telephone and verbal orders, the nurse writes down the full order and reads it back so the provider can confirm it. This “read-back” prevents errors from mishearing.
Answer
C · Write the order down and read it back to the provider to confirm it
16.Prioritization & delegation
Answer: D · Give prescribed opioids and use positioning and a fan to relieve breathlessness
Why this is the answer
In palliative care, opioids are used to relieve breathlessness, along with positioning, a fan and calm reassurance. The aim is comfort, not more investigations.
Answer
D · Give prescribed opioids and use positioning and a fan to relieve breathlessness