Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient is going home with a 24-hour Holter monitor. Which instruction is most important?
AKeep a diary of symptoms and activities with the times
BShower as normal with the monitor on
CStay in bed for the full 24 hours so the trace is clear
DRemove the monitor whenever symptoms occur and restart it
2.Med-surg: cardiovascular & respiratoryHard
Which approach to chest drain removal is commonly taught?
ARemove it during a held breath or expiration, then seal the site
BRemove it and leave the site open to drain for a day
CRemove it slowly while the patient takes a long, deep breath in
DRemove it with the suction still running at full power
3.Med-surg: neuro, endocrine & renalMedium
Which urine finding best distinguishes diabetes insipidus from SIADH?
The day after a lumbar puncture, a patient has a headache that is severe when standing and almost gone when lying flat. Temperature and neck movement are normal. What is the most likely cause?
APost-dural puncture headache
BBacterial meningitis from the procedure
CA migraine triggered by stress
DA subarachnoid haemorrhage
5.Med-surg: GI, perioperative & oncologyMedium
Which complication is more typical of Crohn's disease than of ulcerative colitis?
ABleeding only from the rectum
BInflammation limited to the rectal lining
CFistulas between the bowel and other organs
DDisease that is cured by removing the colon
6.Med-surg: GI, perioperative & oncologyHard
A bag of parenteral nutrition runs out and the next one will not arrive for several hours. Which risk should the nurse anticipate?
AAcute urinary retention
BSevere hyperkalaemia
CRebound hypoglycaemia
DRaised intracranial pressure
7.Clinical nursingMedium
What should a nurse do during a generalised tonic-clonic seizure?
AProtect the head, time the seizure and do not put anything in the mouth
BPut a tongue depressor between the teeth so that the tongue is not bitten
CHold the limbs firmly to stop the jerking and prevent injury
DGive the patient a drink of water
8.Clinical nursingHard
Why must severe chronic hyponatraemia be corrected slowly?
AFast correction causes severe hypoglycaemia and seizures in most patients
BToo-rapid correction can cause osmotic demyelination in the brain
CSodium given quickly causes immediate cardiac arrest
DFast correction makes the kidneys stop producing urine
9.Lab values & electrolytesMedium
A patient taking empagliflozin (an SGLT2 inhibitor) has glucose in the urine but a normal blood glucose. What is the best interpretation?
AA urinary tract infection
BAn expected effect of the drug
CUncontrolled diabetes needing insulin
DA sign of kidney failure
10.Lab values & electrolytesHard
A patient on high-dose dexamethasone has a white cell count of 15 × 10³/µL, mostly mature neutrophils with no bands. They have no fever and no signs of infection. What is the most likely explanation?
AA laboratory error, because steroids always lower the white count
BA steroid effect that moves neutrophils into the circulating blood
CA new leukemia that is confirmed by this result alone
DCertain sepsis that needs antibiotics started without delay
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 55 mmHg (7.3 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic acidosis: pH 7.28, PaCO₂ 22 mmHg (2.9 kPa), HCO₃⁻ 10 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.28PaCO₂ 22 mmHg (2.9 kPa)HCO₃⁻ 10 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1supraventricular tachycardia (SVT)
2atrial fibrillation
3sinus tachycardia
4sinus bradycardia
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2atrial fibrillation
3second-degree AV block type II
4second-degree AV block type I (Wenckebach)
15.Prioritization & delegationMedium
A patient is admitted with diabetic ketoacidosis. Which prescribed treatment is usually started first?
ASubcutaneous long-acting insulin only, given once
BA high-carbohydrate meal
CIV isotonic fluid such as 0.9% sodium chloride
DOral potassium tablets
16.Prioritization & delegationHard
A nurse returns to the station to find four messages. Which one is answered first?
AA colleague asks to swap shifts with them next week because of a family wedding
BThe pharmacy asks when the next delivery should be scheduled
CThe laboratory is calling with a critical potassium result of 2.6 mEq/L
DA family member wants an update on their father’s progress
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Keep a diary of symptoms and activities with the times
Why this is the answer
A Holter monitor records the ECG continuously during normal daily life. A diary of symptoms and activities lets the reviewer match symptoms such as palpitations or dizziness to the rhythm. The device is kept dry unless it is designed to be waterproof.
Answer
A · Keep a diary of symptoms and activities with the times
2.Med-surg: cardiovascular & respiratory
Answer: A · Remove it during a held breath or expiration, then seal the site
Why this is the answer
Many guidelines suggest removing the tube at the end of a deep breath held (Valsalva) or during expiration, so that the pressure in the chest is positive. The wound is closed with a suture or occlusive dressing, the patient monitored for recurrent pneumothorax and a chest X-ray done if indicated. Analgesia beforehand is good practice.
Answer
A · Remove it during a held breath or expiration, then seal the site
3.Med-surg: neuro, endocrine & renal
Answer: B · DI gives dilute urine; SIADH gives concentrated urine
Why this is the answer
In DI, lack of ADH effect causes large volumes of dilute urine (specific gravity often below 1.005) with high serum sodium. In SIADH, excess ADH causes low urine output with concentrated urine and low serum sodium.
Answer
B · DI gives dilute urine; SIADH gives concentrated urine
4.Med-surg: neuro, endocrine & renal
Answer: A · Post-dural puncture headache
Why this is the answer
A positional headache after a lumbar puncture, without fever or neck stiffness, fits a CSF leak. It is managed with rest, fluids, analgesia and caffeine, and an epidural blood patch if it persists. Fever or neck stiffness would suggest infection instead.
Answer
A · Post-dural puncture headache
5.Med-surg: GI, perioperative & oncology
Answer: C · Fistulas between the bowel and other organs
Why this is the answer
Transmural inflammation in Crohn's disease can create fistulas, abscesses and strictures. Ulcerative colitis is mucosal, and removing the colon and rectum is curative.
Answer
C · Fistulas between the bowel and other organs
6.Med-surg: GI, perioperative & oncology
Answer: C · Rebound hypoglycaemia
Why this is the answer
Stopping PN suddenly can cause hypoglycaemia because insulin levels stay high for a while. Glucose is monitored, and a glucose infusion may be given according to local policy.
Answer
C · Rebound hypoglycaemia
7.Clinical nursing
Answer: A · Protect the head, time the seizure and do not put anything in the mouth
Why this is the answer
Remove nearby hazards, cushion the head, note the time and do not restrain or put objects in the mouth. Once jerking stops, place the patient in the recovery position and check the airway.
Answer
A · Protect the head, time the seizure and do not put anything in the mouth
8.Clinical nursing
Answer: B · Too-rapid correction can cause osmotic demyelination in the brain
Why this is the answer
In chronic hyponatraemia brain cells adapt to the low tonicity. A rapid rise in sodium draws water out too fast and can cause osmotic demyelination, so the correction rate is limited and sodium is checked often.
Answer
B · Too-rapid correction can cause osmotic demyelination in the brain
9.Lab values & electrolytes
Answer: B · An expected effect of the drug
Why this is the answer
SGLT2 inhibitors block glucose reabsorption in the proximal tubule, so glycosuria is expected even with normal blood glucose. Urine glucose cannot be used to monitor control in these patients. The drugs also raise the risk of genital infections and DKA.Checked against:Ketones blood test · MedlinePlus (NIH) (2025)
Answer
B · An expected effect of the drug
10.Lab values & electrolytes
Answer: B · A steroid effect that moves neutrophils into the circulating blood
Why this is the answer
Corticosteroids raise the neutrophil count by releasing marginated neutrophils and slowing their exit from the blood, usually without a left shift. The nurse still assesses carefully, because steroids can also hide the usual signs of infection.
Answer
B · A steroid effect that moves neutrophils into the circulating blood
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 29.25 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|55 − 40| = 15 mmHg → 1.5 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·1.5 = 29.25 mmol/L
Answer
HCO₃⁻ = 29.25 mmol/L
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·10 + 8 = 23 → 21–25 mmHg
Compare
measured: 22 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: sinus tachycardia
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 12 small boxes, 1500 ÷ 12 ≈ 125 per minute.
2. Rhythm: regular, every R–R is 0.48 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
sinus tachycardia
Answer
sinus tachycardia
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 0.96 s, 63 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: lengthens 0.16 → 0.28 → 0.36 s, then a P wave is not conducted.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: C · IV isotonic fluid such as 0.9% sodium chloride
Why this is the answer
Patients with DKA are severely dehydrated, so IV isotonic fluid is started first. IV insulin follows, with close monitoring of potassium, which can fall quickly.
Answer
C · IV isotonic fluid such as 0.9% sodium chloride
16.Prioritization & delegation
Answer: C · The laboratory is calling with a critical potassium result of 2.6 mEq/L
Why this is the answer
A critical potassium of 2.6 mEq/L can cause life-threatening arrhythmias, so it is acted on first: the nurse assesses the patient and informs the provider. The other calls can wait.
Answer
C · The laboratory is calling with a critical potassium result of 2.6 mEq/L