Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why are nitrates used with great caution in right ventricular infarction?
AThe right ventricle depends on preload, so BP can fall sharply
BNitrates make the infarct spread into the left ventricle
CNitrates cause dangerous hyperkalaemia in this type of infarct
DNitrates are not absorbed when the right ventricle is affected
2.Med-surg: cardiovascular & respiratoryHard
A hypotensive patient has a temperature of 39.2 °C, warm flushed skin, a bounding pulse and a fast heart rate. Which type of shock is most likely?
AEarly septic (distributive) shock
BHypovolaemic shock from bleeding
CObstructive shock from tamponade
DCardiogenic shock
3.Med-surg: neuro, endocrine & renalMedium
In a patient with an acute spinal cord injury at C6, which picture suggests neurogenic shock?
ANormal blood pressure, fast pulse and a high fever
BHigh blood pressure, slow pulse and a pounding headache
CLow blood pressure, fast pulse and cold, clammy skin
DLow blood pressure, slow pulse and warm, dry skin
4.Med-surg: neuro, endocrine & renalHard
A haemodialysis patient with a tunnelled central venous catheter develops fever and rigors soon after dialysis starts. What should the nurse suspect and do?
ANormal reaction to dialysis; continue and give paracetamol only
BDialysis disequilibrium; speed up dialysis to finish sooner
CCatheter-related bloodstream infection; stop, take cultures and escalate
DAir embolism; tilt the patient head-up and continue
5.Med-surg: GI, perioperative & oncologyMedium
A patient has taken oral prednisolone daily for many months. Why is this important before surgery?
ASteroids prevent all wound infections after surgery
BSteroids make the anaesthetic drugs last much longer
CSteroids must always be stopped a full week before any type of surgery
DThey may need extra steroid cover to prevent an adrenal crisis
6.Med-surg: GI, perioperative & oncologyHard
A patient with hepatic encephalopathy is restless at night. A benzodiazepine is suggested for sleep. What should the nurse do?
AGive it and stop the lactulose to avoid diarrhoea
BGive it at double the usual dose to ensure sleep
CQuestion it, as sedatives can worsen encephalopathy
DGive it, as the liver does not affect sedatives
7.Clinical nursingMedium
Within which time window is IV thrombolysis generally given for acute ischaemic stroke?
AWithin 48 hours of the onset of symptoms
BAt any time within a week
COnly after 24 hours
DWithin 4.5 hours of symptom onset
8.Clinical nursingHard
A nurse teaches a patient with diabetes about foot care. Which statement shows a need for further teaching?
A"I will walk barefoot at home to toughen my feet."
B"I will see the podiatrist about hard skin."
C"I will check my feet every day for cuts or blisters."
D"I will wear well-fitting shoes."
9.Lab values & electrolytesMedium
A patient has burning on urination and frequency. The dipstick is positive for nitrites and leukocyte esterase, and a urine culture is ordered. When should the sample be taken?
AAfter the symptoms have fully settled
BBefore the first dose of antibiotic
CAfter 3 days of antibiotic treatment
DAt any time, as antibiotics do not matter
10.Lab values & electrolytesHard
A patient’s total calcium is 7.9 mg/dL (2.0 mmol/L), with an albumin of 2.4 g/dL (24 g/L) and no symptoms. Which test would best clarify whether true hypocalcemia is present?
AA serum sodium
BAn ionized calcium
CA urine specific gravity
DAn HbA1c
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.62, PaCO₂ 41 mmHg (5.5 kPa) and HCO₃⁻ 41 mmol/L. The primary disorder is metabolic alkalosis. How far is it compensated? Click your answer.
pH 7.62PaCO₂ 41 mmHg (5.5 kPa)HCO₃⁻ 41 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 28% oxygen shows PaO₂ 51 mmHg (6.8 kPa) and PaCO₂ 42 mmHg (5.6 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Bazett’s formula QTc = QT/√RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1ventricular tachycardia
2idioventricular rhythm
3third-degree (complete) AV block
4asystole
15.Prioritization & delegationMedium
A patient has a new plaster cast that is still drying. How should the nurse handle it?
AWith the palms of the hands, not the fingertips
BBy resting it directly on a hard surface
CWith the fingertips, pressing firmly to test it
DBy covering it tightly with a plastic sheet
16.Prioritization & delegationHard
A trauma patient has an open leg fracture, absent breath sounds on one side, a trachea shifted to the other side and a falling blood pressure. Which problem is the priority?
AThe pain from the fracture
BThe suspected tension pneumothorax
CThe risk of wound infection
DThe open fracture of the leg
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · The right ventricle depends on preload, so BP can fall sharply
Why this is the answer
In right ventricular infarction cardiac output depends heavily on venous filling. Venodilators such as nitrates (and diuretics or opioids) can cause a dramatic fall in blood pressure. These patients often need careful fluid administration instead.
Answer
A · The right ventricle depends on preload, so BP can fall sharply
2.Med-surg: cardiovascular & respiratory
Answer: A · Early septic (distributive) shock
Why this is the answer
Early septic shock often causes warm peripheries and bounding pulses because of widespread vasodilation. Cardiogenic, hypovolaemic and obstructive shock usually cause cool, clammy skin from vasoconstriction. Septic shock can later become "cold" as it progresses.
Answer
A · Early septic (distributive) shock
3.Med-surg: neuro, endocrine & renal
Answer: D · Low blood pressure, slow pulse and warm, dry skin
Why this is the answer
Neurogenic shock follows injury at T6 or above. Loss of sympathetic tone causes vasodilation (warm, dry skin) and unopposed vagal activity (bradycardia). Hypovolaemic shock causes tachycardia and cold, clammy skin; a trauma patient may have both, so bleeding must still be looked for.
Answer
D · Low blood pressure, slow pulse and warm, dry skin
4.Med-surg: neuro, endocrine & renal
Answer: C · Catheter-related bloodstream infection; stop, take cultures and escalate
Why this is the answer
Fever and rigors when dialysis starts through a central catheter strongly suggest a catheter-related bloodstream infection. Dialysis is stopped or adjusted per protocol, blood cultures are taken (from the catheter and peripherally), the team is informed and IV antibiotics are started as prescribed. The exit site is inspected.
Answer
C · Catheter-related bloodstream infection; stop, take cultures and escalate
5.Med-surg: GI, perioperative & oncology
Answer: D · They may need extra steroid cover to prevent an adrenal crisis
Why this is the answer
Long-term steroids suppress the adrenal glands, so they cannot raise cortisol in response to surgical stress. Extra steroid cover may be prescribed, and steroids are not stopped suddenly. Healing may also be slower.
Answer
D · They may need extra steroid cover to prevent an adrenal crisis
6.Med-surg: GI, perioperative & oncology
Answer: C · Question it, as sedatives can worsen encephalopathy
Why this is the answer
Benzodiazepines and opioids accumulate in liver failure and can precipitate or worsen encephalopathy. Look for triggers such as infection, constipation, GI bleeding, dehydration and electrolyte changes. Benzodiazepines for alcohol withdrawal are an exception, used with care.
Answer
C · Question it, as sedatives can worsen encephalopathy
7.Clinical nursing
Answer: D · Within 4.5 hours of symptom onset
Why this is the answer
Thrombolysis with alteplase is generally given within 4.5 hours of onset after a scan excludes haemorrhage. Knowing when the patient was last seen well is therefore essential.
Answer
D · Within 4.5 hours of symptom onset
8.Clinical nursing
Answer: A · "I will walk barefoot at home to toughen my feet."
Why this is the answer
Diabetic neuropathy and poor circulation mean small injuries can become ulcers. Patients should avoid walking barefoot, inspect their feet daily and get professional foot care.
Answer
A · "I will walk barefoot at home to toughen my feet."
9.Lab values & electrolytes
Answer: B · Before the first dose of antibiotic
Why this is the answer
The culture sample is taken before antibiotics, so the organism can be grown and its sensitivities tested. A sample taken after antibiotics may give a false negative culture.
Answer
B · Before the first dose of antibiotic
10.Lab values & electrolytes
Answer: B · An ionized calcium
Why this is the answer
Low albumin lowers total calcium without necessarily lowering the active, ionized calcium. Measuring ionized calcium directly is the most reliable way to decide whether treatment is needed.Checked against:Calcium - ionized · MedlinePlus (NIH) (2025); Calcium Blood Test · MedlinePlus (NIH) (2024)
Answer
B · An ionized calcium
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.62: alkalaemia (above 7.45)
PaCO₂ 41 mmHg: normal (35–45)
HCO₃⁻ 41 mmol/L: high (22–26)
Compensation
Clinically, also check the expected compensation: for a metabolic alkalosis PaCO₂ ≈ 0.7·HCO₃⁻ + 21 = 47.7–51.7 mmHg, so the measured 41 mmHg points to an additional respiratory alkalosis (a mixed disorder). The answer above is the ROME exam classification.
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: A–a gradient = 96.14 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 12 × 0.04 = 0.48 s
RR = 28 × 0.04 = 1.12 s
Bazett’s formula
QTc = 0.48/√1.12 = 0.48/1.058 = 0.454 s
Answer
QTc = 0.454 s
Between the usual limits for men (about 0.45 s) and women (about 0.46 s): borderline, depending on the reference used. (454 ms)
14.ECG rhythm strip interpretation
Answer: idioventricular rhythm
More ventricular rhythms: torsades de pointes is a polymorphic ventricular tachycardia, usually 150–250/min, in which the wide complexes change in height and twist around the baseline, pointing up for a few beats and then down. Textbooks link it to a prolonged QT interval, and magnesium sulfate is the drug resuscitation guidelines name for it. An idioventricular rhythm is a ventricular escape rhythm: regular, wide QRS (0.12 s or more), no P waves, at 20–40/min (an accelerated idioventricular rhythm runs at 40–100/min). Monomorphic VT has identical wide complexes at more than 100/min. VF is chaotic, without any repeating complex.
Five steps
1. Rate: R–R = 56 small boxes, 1500 ÷ 56 ≈ 27 per minute.
2. Rhythm: regular, every R–R is 2.24 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.16 s, wide (0.12 s or more) and bizarre, with the T wave pointing the other way.
Interpretation
idioventricular rhythm
Answer
idioventricular rhythm
An idioventricular rhythm is an escape rhythm: the ventricles take over because the pacemakers above them have failed.
15.Prioritization & delegation
Answer: A · With the palms of the hands, not the fingertips
Why this is the answer
A wet plaster cast can be dented by fingertips, causing pressure points under the cast. It is handled with the palms, supported on pillows and left uncovered to dry.
Answer
A · With the palms of the hands, not the fingertips
16.Prioritization & delegation
Answer: B · The suspected tension pneumothorax
Why this is the answer
A shifted trachea, absent breath sounds and hypotension suggest tension pneumothorax, which threatens breathing and circulation within minutes. The fracture is important, but it comes after the immediate life threat.