Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient takes both digoxin and furosemide. Why does the nurse watch the potassium level closely?
ALow potassium increases the risk of digoxin toxicity
BHigh potassium is the main effect of furosemide
CPotassium has no link with either medicine
DLow potassium makes digoxin stop working completely
2.Med-surg: cardiovascular & respiratoryHard
During a thrombolytic infusion for an MI, the patient develops a sudden severe headache, vomiting and new confusion. What should the nurse do first?
AGive a second dose to finish the treatment
BStop the infusion and call for urgent medical help
CSlow the infusion and give an antiemetic
DContinue the infusion, as headache is a common side effect
3.Med-surg: neuro, endocrine & renalMedium
A patient with advanced CKD asks how to manage indigestion. Which option should they avoid?
ARaising the head of the bed at night
BAvoiding large meals late in the evening
CMagnesium-containing antacids
DEating smaller, more frequent meals
4.Med-surg: neuro, endocrine & renalHard
A patient taking digoxin has a potassium of 2.9 mmol/L. Why is this especially dangerous?
ALow potassium increases the risk of digoxin toxicity
BDigoxin raises the potassium to dangerous levels
CDigoxin stops working when potassium is low
DLow potassium makes digoxin leave the body faster
5.Med-surg: GI, perioperative & oncologyMedium
Which nursing intervention best reduces preoperative anxiety?
AKeeping family members away until after surgery
BAvoiding talking about the operation at all
CTelling the patient that there is nothing to worry about
DExplaining what will happen and answering questions
6.Med-surg: GI, perioperative & oncologyHard
A dying patient has noisy, rattling breathing. The patient seems unaware, but the family is distressed. What is the best nursing approach?
APerform deep suction every hour
BGive large volumes of IV fluid to loosen and thin the secretions
CAsk the family to leave the room
DReposition, explain the cause and give prescribed drugs if needed
7.Clinical nursingMedium
Which statement about storing insulin is correct?
AUnopened insulin is kept in the fridge and must not be frozen
BInsulin never expires once opened
CInsulin should be kept in direct sunlight
DAll insulin should be stored in the freezer to keep it fresh
8.Clinical nursingHard
A patient with central chest pain has ST elevation on the 12-lead ECG. What is the main aim of urgent treatment?
AStrict bed rest for several days before deciding on treatment
BWaiting for the troponin result before taking any action
CStarting a cholesterol-lowering drug before any other treatment is given
DRestoring blood flow through the blocked coronary artery quickly
9.Lab values & electrolytesMedium
A patient on phenytoin has a level of 28 mcg/mL (usual range about 10–20 mcg/mL). Which findings would the nurse expect?
AHyperactive behavior and insomnia only
BHunger and weight gain
CTall, peaked T waves
DNystagmus, unsteady gait and slurred speech
10.Lab values & electrolytesHard
A patient with a calcium of 6.8 mg/dL (1.7 mmol/L) suddenly develops noisy breathing and a hoarse voice. What does this suggest?
AA normal response that will pass without treatment
BA common cold that started this morning
CAnxiety about the blood results, which needs calm reassurance
DLaryngospasm, an emergency needing urgent help and IV calcium
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 143 mmol/L, glucose 22.1 mmol/L and urea 25 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 143 mmol/Lglucose 22.1 mmol/Lurea 25 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.32, PaCO₂ 30 mmHg (4.0 kPa), HCO₃⁻ 15 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.32PaCO₂ 30 mmHg (4.0 kPa)HCO₃⁻ 15 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2sinus bradycardia
3junctional rhythm
4first-degree AV block
14.ECG rhythm strip interpretationHard
This patient has a pacemaker. Interpret the lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1dual-chamber (AV) paced rhythm
2third-degree (complete) AV block
3paced rhythm, failure to capture
4idioventricular rhythm
15.Prioritization & delegationMedium
A patient receiving chemotherapy has a temperature of 38.3 °C and a very low neutrophil count. What should the nurse do?
ADocument the reading and mention it at the next handover
BRecheck the temperature in four hours before telling anyone
CReport it at once, because cultures and antibiotics are needed quickly
DGive a cool shower and offer extra fluids, then wait and see what happens
16.Prioritization & delegationHard
Two patients on the unit have the same surname. What should the nurse do before giving a medication?
AAsk a nursing assistant which patient is which
BCheck two identifiers against the wristband and the medication record
CUse the room number as the main identifier
DAsk the patient, “Are you Mr Smith?” and give the drug once he says yes
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Low potassium increases the risk of digoxin toxicity
Why this is the answer
Digoxin binds to the Na⁺/K⁺-ATPase pump at the site potassium normally uses. When potassium is low, more digoxin binds, so toxicity and arrhythmias become more likely. Loop diuretics commonly cause hypokalaemia, so the combination needs monitoring.
Answer
A · Low potassium increases the risk of digoxin toxicity
2.Med-surg: cardiovascular & respiratory
Answer: B · Stop the infusion and call for urgent medical help
Why this is the answer
Sudden neurological change during or after thrombolysis suggests intracranial haemorrhage. The infusion is stopped immediately, help is called, and urgent CT and reversal are considered. Neurological observations continue.
Answer
B · Stop the infusion and call for urgent medical help
3.Med-surg: neuro, endocrine & renal
Answer: C · Magnesium-containing antacids
Why this is the answer
Magnesium and aluminium are excreted by the kidneys and can accumulate in kidney failure. Patients with CKD should check with a pharmacist before using over-the-counter remedies, including laxatives and NSAIDs.
Answer
C · Magnesium-containing antacids
4.Med-surg: neuro, endocrine & renal
Answer: A · Low potassium increases the risk of digoxin toxicity
Why this is the answer
Digoxin binds to the sodium–potassium pump, and low potassium increases this binding. Hypokalaemia therefore raises the risk of toxicity and arrhythmias, even with a normal digoxin level. The potassium is corrected and the patient monitored.
Answer
A · Low potassium increases the risk of digoxin toxicity
5.Med-surg: GI, perioperative & oncology
Answer: D · Explaining what will happen and answering questions
Why this is the answer
Clear information about what to expect, including pain control and recovery, reduces anxiety and can improve recovery. False reassurance does not address the patient's concerns.
Answer
D · Explaining what will happen and answering questions
6.Med-surg: GI, perioperative & oncology
Answer: D · Reposition, explain the cause and give prescribed drugs if needed
Why this is the answer
Noisy respiratory secretions near death come from secretions in the throat that the patient cannot clear. Repositioning, explanation and anticholinergic drugs may help; deep suction is usually distressing and ineffective.
Answer
D · Reposition, explain the cause and give prescribed drugs if needed
7.Clinical nursing
Answer: A · Unopened insulin is kept in the fridge and must not be frozen
Why this is the answer
Unopened insulin is refrigerated; in-use pens or vials are usually kept at room temperature for a limited time stated by the manufacturer. Frozen or overheated insulin must be discarded.
Answer
A · Unopened insulin is kept in the fridge and must not be frozen
8.Clinical nursing
Answer: D · Restoring blood flow through the blocked coronary artery quickly
Why this is the answer
ST-elevation myocardial infarction means a coronary artery is usually completely blocked. Urgent reperfusion by primary PCI, or thrombolysis if PCI is not available in time, limits the amount of heart muscle that dies.
Answer
D · Restoring blood flow through the blocked coronary artery quickly
9.Lab values & electrolytes
Answer: D · Nystagmus, unsteady gait and slurred speech
Why this is the answer
Phenytoin toxicity causes nystagmus, ataxia, slurred speech and drowsiness. The nurse holds the dose and informs the prescriber. Low albumin increases the free (active) drug, so toxicity can occur even with a normal total level.
Answer
D · Nystagmus, unsteady gait and slurred speech
10.Lab values & electrolytes
Answer: D · Laryngospasm, an emergency needing urgent help and IV calcium
Why this is the answer
Severe hypocalcemia can cause spasm of the larynx, which blocks the airway. The nurse calls for urgent help, supports the airway and prepares IV calcium gluconate as prescribed, with cardiac monitoring.Checked against:Hypocalcemia (StatPearls) · StatPearls (NCBI Bookshelf) (2026)
Answer
D · Laryngospasm, an emergency needing urgent help and IV calcium
11.Arterial blood gas interpretation
Answer: Osm = 333 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·143 + 22.1 + 25 = 333.1 ≈ 333 mOsm/kg
Answer
Osm = 333 mOsm/kg
12.Arterial blood gas interpretation
Answer: appropriate compensation
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·15 + 8 = 30.5 → 28.5–32.5 mmHg
Compare
measured: 30 mmHg → appropriate compensation
Answer
appropriate compensation
13.ECG rhythm strip interpretation
Answer: junctional rhythm
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 34 small boxes, 1500 ÷ 34 ≈ 44 per minute.
2. Rhythm: regular, every R–R is 1.36 s.
3. P waves: inverted, just before each QRS.
4. PR interval: 0.10 s, shorter than 0.12 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
junctional rhythm
Answer
junctional rhythm
14.ECG rhythm strip interpretation
Answer: paced rhythm, failure to capture
Paced rhythms: a pacemaker impulse shows as a narrow vertical pacing spike. After a ventricular spike the QRS is wide (0.12 s or more), because the impulse spreads from the lead through the muscle instead of the conduction system; with right-ventricular pacing it is often mostly negative in lead II. A spike before each P wave means atrial pacing, and a dual-chamber (AV) pacemaker shows an atrial spike and a P wave, then, after the programmed AV delay, a ventricular spike and a wide QRS. Capture means every spike is followed by a depolarisation. Failure to capture is a spike without a P wave or QRS after it; failure to sense (spikes that ignore the patient’s own beats) and failure to pace (no spike when one is due) are the other classic malfunctions.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: the pacing spikes are regular (every 1.00 s), but the R–R is not, because a QRS is missing after some spikes.
3. P waves: none visible.
4. PR interval: not measurable.
5. QRS: 0.16 s and wide after the captured spikes; one spike is not followed by a QRS (no capture).
Interpretation
paced rhythm, failure to capture
Answer
paced rhythm, failure to capture
Failure to capture: the pacemaker fires but the heart does not respond. Textbooks treat it as urgent to report, because the patient may depend on the pacemaker.
15.Prioritization & delegation
Answer: C · Report it at once, because cultures and antibiotics are needed quickly
Why this is the answer
Neutropenic fever is a medical emergency. The patient may have few other signs of infection, so the nurse reports it immediately so that cultures can be taken and IV antibiotics started.
Answer
C · Report it at once, because cultures and antibiotics are needed quickly
16.Prioritization & delegation
Answer: B · Check two identifiers against the wristband and the medication record
Why this is the answer
The nurse uses at least two identifiers, such as full name and date of birth, checked against the wristband and record. Open questions (“Please tell me your name”) are safer than yes/no questions.
Answer
B · Check two identifiers against the wristband and the medication record