Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
What is the main problem in heart failure with preserved ejection fraction?
AA dilated ventricle that cannot contract strongly
BA leaking aortic valve
CA stiff ventricle that fills poorly in diastole
DA blocked pulmonary artery
2.Med-surg: cardiovascular & respiratoryHard
An 84-year-old with heart failure becomes breathless with new crackles and a rising blood pressure during a blood transfusion. What should the nurse suspect?
AA mild febrile reaction
BAn acute haemolytic reaction from wrong blood
CNormal effects of the transfusion
DTransfusion-associated circulatory overload
3.Med-surg: neuro, endocrine & renalMedium
After a lumbar discectomy, which finding should the nurse report promptly?
AMild pain at the wound site
BNew weakness or numbness in the legs
CStiffness when getting out of bed
DA dry, intact wound dressing
4.Med-surg: neuro, endocrine & renalHard
A patient with type 1 diabetes is vomiting at home. Their glucose is 12 mmol/L (216 mg/dL), and blood ketones are 3.5 mmol/L. What advice is correct?
ADrink less fluid to stop the vomiting
BWait until the glucose is above 20 mmol/L (360 mg/dL)
CSeek urgent hospital assessment for possible DKA
DStop insulin until the vomiting has settled
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps prevent dumping syndrome after gastrectomy?
ASmall, frequent meals low in simple sugars, with fluids between meals
BSit upright and walk briskly straight after every meal
CThree large meals a day with plenty of sweet drinks with each meal
DA high-sugar diet with fruit juice to keep energy levels up
6.Med-surg: GI, perioperative & oncologyHard
A patient with 35% TBSA burns is entering the hypermetabolic phase. Which nutrition plan is most appropriate?
AEarly enteral feeding, high in energy and protein
BClear fluids only until the burn wounds have healed
CNil by mouth for two weeks to rest the gut fully
DA low-protein diet to protect the kidneys from damage
7.Clinical nursingMedium
A patient with type 1 diabetes is vomiting and eating little. What is correct sick-day advice?
ACheck glucose once a day only
BStop insulin until eating normally again to avoid hypoglycaemia
CDo not stop insulin; check glucose and ketones more often
DHalve fluid intake to prevent vomiting
8.Clinical nursingHard
A patient taking regular ibuprofen suddenly develops severe upper abdominal pain, a rigid abdomen and becomes tachycardic. What is most likely?
AConstipation
BA perforated peptic ulcer
CIndigestion that will settle with antacids
DIrritable bowel syndrome
9.Lab values & electrolytesMedium
A patient takes valproate (valproic acid) for epilepsy. Which tests are monitored regularly?
ATroponin and B-type natriuretic peptide
BThyroid function and serum calcium
CSerum lithium and urine specific gravity
DLiver function tests and platelet count
10.Lab values & electrolytesHard
A patient with blood pressure that is hard to control has a potassium of 2.9 mEq/L, a sodium of 144 mEq/L and a raised serum bicarbonate, without taking a diuretic. Which condition is most likely?
ASyndrome of inappropriate ADH
BPrimary hyperaldosteronism
CPrimary adrenal insufficiency
DCentral diabetes insipidus
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 16 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 16 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 32 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 32 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2atrial flutter, 4:1 conduction
3junctional rhythm
4atrial flutter, 2:1 conduction
14.ECG rhythm strip interpretationHard
A monitored patient is found unresponsive and not breathing normally, and no carotid pulse can be felt. The monitor shows this organised rhythm. What is this situation called? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1asystole
2ventricular fibrillation
3pulseless electrical activity (PEA)
4sinus tachycardia
15.Prioritization & delegationMedium
On the first day after abdominal surgery, a patient has a temperature of 37.9 °C and reduced breath sounds at the lung bases. Which nursing action is most helpful?
ARestrict oral fluids so that the lungs do not fill up with extra fluid
BKeep the patient lying flat in bed to rest the incision fully
CEncourage deep breathing, coughing and use of the incentive spirometer
DGive a cough suppressant so that the incision is not strained
16.Prioritization & delegationHard
A patient is admitted with inhalational anthrax. Which precautions are needed?
AFull contact and droplet precautions for all staff and visitors on the unit
BDroplet precautions with a surgical mask for everyone who enters
CAirborne precautions in a negative-pressure room for the whole of the hospital stay
DStandard precautions, because it does not usually spread from person to person
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · A stiff ventricle that fills poorly in diastole
Why this is the answer
In HFpEF, the left ventricle is stiff and relaxes poorly, so filling pressures rise and cause congestion even though the ejection fraction is normal. It is common in older people with hypertension, diabetes and obesity. HFrEF is mainly a problem of contraction.
Answer
C · A stiff ventricle that fills poorly in diastole
2.Med-surg: cardiovascular & respiratory
Answer: D · Transfusion-associated circulatory overload
Why this is the answer
Transfusion-associated circulatory overload causes breathlessness, crackles, raised BP and JVP during or soon after transfusion, especially in older people and those with heart or kidney disease. The transfusion is stopped or slowed, the patient sat up and given oxygen, and diuretics may be prescribed. Slow rates and single units with reassessment reduce the risk.
Answer
D · Transfusion-associated circulatory overload
3.Med-surg: neuro, endocrine & renal
Answer: B · New weakness or numbness in the legs
Why this is the answer
New or worsening leg weakness, numbness or problems passing urine may indicate a haematoma or nerve root compression and need urgent review. Mild wound pain and stiffness are expected.
Answer
B · New weakness or numbness in the legs
4.Med-surg: neuro, endocrine & renal
Answer: C · Seek urgent hospital assessment for possible DKA
Why this is the answer
Blood ketones above 3 mmol/L, especially with vomiting, mean a high risk of DKA, even if the glucose is only moderately raised. The patient needs urgent assessment. Insulin should not be stopped.
Answer
C · Seek urgent hospital assessment for possible DKA
5.Med-surg: GI, perioperative & oncology
Answer: A · Small, frequent meals low in simple sugars, with fluids between meals
Why this is the answer
Small meals, fewer simple sugars, more protein and fibre, and taking fluids between rather than with meals slow emptying and reduce fluid shifts. Lying down briefly after meals can also help.
Answer
A · Small, frequent meals low in simple sugars, with fluids between meals
6.Med-surg: GI, perioperative & oncology
Answer: A · Early enteral feeding, high in energy and protein
Why this is the answer
Major burns cause a prolonged hypermetabolic, catabolic state with muscle loss. Early enteral nutrition (often within 24 hours) with high energy and protein, plus micronutrients, supports wound healing and immunity and helps protect the gut barrier. Weight and intake are monitored.
Answer
A · Early enteral feeding, high in energy and protein
7.Clinical nursing
Answer: C · Do not stop insulin; check glucose and ketones more often
Why this is the answer
Stopping insulin in type 1 diabetes can quickly cause DKA. Patients should continue insulin, monitor glucose and ketones, drink fluids and seek help if ketones rise.
Answer
C · Do not stop insulin; check glucose and ketones more often
8.Clinical nursing
Answer: B · A perforated peptic ulcer
Why this is the answer
Sudden severe pain with a board-like abdomen suggests perforation and peritonitis. The patient needs nil by mouth, IV access, analgesia and urgent surgical review.
Answer
B · A perforated peptic ulcer
9.Lab values & electrolytes
Answer: D · Liver function tests and platelet count
Why this is the answer
Valproate can cause liver toxicity and thrombocytopenia, so liver tests and the platelet count are monitored. It can also raise ammonia; confusion or vomiting should prompt an ammonia level.Checked against:Valproic Acid · StatPearls (NCBI Bookshelf) (2024)
Answer
D · Liver function tests and platelet count
10.Lab values & electrolytes
Answer: B · Primary hyperaldosteronism
Why this is the answer
Excess aldosterone causes sodium and water retention (hypertension), potassium loss (hypokalemia) and hydrogen ion loss (metabolic alkalosis). Adrenal insufficiency causes the opposite pattern, with low sodium and high potassium.Checked against:Primary and secondary hyperaldosteronism · MedlinePlus (NIH) (2025); Alkalosis · StatPearls (NCBI Bookshelf) (2024)
Answer
B · Primary hyperaldosteronism
11.Arterial blood gas interpretation
Answer: PaCO₂ = 32 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·16 + 8 = 32 mmHg
range: 30–34 mmHg
Answer
PaCO₂ = 32 mmHg
12.Arterial blood gas interpretation
Answer: PaCO₂ = 43.4 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·32 + 21 = 43.4 mmHg
Answer
PaCO₂ = 43.4 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: atrial fibrillation
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 9 QRS complexes in 6 s, × 10 = 90 per minute.
2. Rhythm: irregularly irregular, R–R from 0.56 to 0.92 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.06 s, narrow (below 0.12 s).
Interpretation
atrial fibrillation
Answer
atrial fibrillation
14.ECG rhythm strip interpretation
Answer: pulseless electrical activity (PEA)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 12 small boxes, 1500 ÷ 12 ≈ 125 per minute.
2. Rhythm: regular, every R–R is 0.48 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
sinus tachycardia
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
pulseless electrical activity (PEA)
Answer
pulseless electrical activity (PEA)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: C · Encourage deep breathing, coughing and use of the incentive spirometer
Why this is the answer
Reduced basal breath sounds and a mild temperature early after surgery often mean atelectasis. Deep breathing, coughing, incentive spirometry and early mobilization help re-expand the lungs.
Answer
C · Encourage deep breathing, coughing and use of the incentive spirometer
16.Prioritization & delegation
Answer: D · Standard precautions, because it does not usually spread from person to person
Why this is the answer
Inhalational anthrax is not spread from person to person, so standard precautions are used. Contact precautions may be added for skin (cutaneous) anthrax with draining lesions.
Answer
D · Standard precautions, because it does not usually spread from person to person