Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with diabetes is starting a beta-blocker. What should the nurse teach about hypoglycaemia?
AInsulin should be stopped while taking a beta-blocker
BSome warning signs, such as a fast heartbeat, may be masked
CThe beta-blocker will prevent all episodes of hypoglycaemia
DHypoglycaemia will always cause a very slow and weak pulse
2.Med-surg: cardiovascular & respiratoryHard
After cardiac catheterisation via the radial artery, which assessment is most important?
APupil size and reaction to light every 15 minutes
BUrine specific gravity every four hours
CBowel sounds and abdominal girth every hour after the test
DCirculation, sensation and movement of the hand, and the site
3.Med-surg: neuro, endocrine & renalMedium
Several hours after a carotid endarterectomy, which finding needs the most urgent action?
AA blood pressure slightly above the baseline
BAn expanding neck swelling with noisy breathing
CMild pain at the incision site
DA small amount of dried blood on the dressing
4.Med-surg: neuro, endocrine & renalHard
A student has fever, a severe headache, a spreading non-blanching rash and a BP of 85/50 mmHg. A lumbar puncture is planned. What is the priority?
AArrange a CT scan of the head before any treatment
BGive paracetamol (acetaminophen) and recheck observations in an hour
CGive IV antibiotics at once and start sepsis treatment
DWait until after the lumbar puncture before giving antibiotics
5.Med-surg: GI, perioperative & oncologyMedium
Why is the time a surgical limb tourniquet is inflated carefully recorded?
ALong inflation can cause nerve and muscle damage
BThe tourniquet slowly loses all its air after one minute
CIt shows how long the anaesthetic gas was used
DThe surgeon is paid per minute of use
6.Med-surg: GI, perioperative & oncologyHard
Which patient is at highest risk of respiratory depression from a postoperative opioid PCA?
AA patient with no other medical problems who receives paracetamol
BA patient whose pain score is 8/10 and who is wide awake and alert
CA young patient who has used opioids regularly for many months
DAn opioid-naive older patient with sleep apnoea who also takes a sedative
7.Clinical nursingMedium
What should a nurse do during a generalised tonic-clonic seizure?
AHold the limbs firmly to stop the jerking and prevent injury
BPut a tongue depressor between the teeth so that the tongue is not bitten
CProtect the head, time the seizure and do not put anything in the mouth
DGive the patient a drink of water
8.Clinical nursingHard
Why should chronic hypernatraemia be corrected gradually?
AFast correction causes osmotic demyelination from swelling of the kidneys
BSlow correction is only needed in children
CFast correction causes severe hyperkalaemia
DLowering the sodium too fast can cause cerebral oedema
9.Lab values & electrolytesMedium
A patient takes valproate (valproic acid) for epilepsy. Which tests are monitored regularly?
ASerum lithium and urine specific gravity
BLiver function tests and platelet count
CThyroid function and serum calcium
DTroponin and B-type natriuretic peptide
10.Lab values & electrolytesHard
A patient on a thiazide diuretic has a sodium of 129 mEq/L, a potassium of 3.2 mEq/L and feels weak. Which explanation fits best?
AThe results are typical of kidney failure
BThe patient has primary hyperaldosteronism with high sodium
CThe patient is overhydrated from IV fluids only
DThe diuretic is causing sodium and potassium loss
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 151 mmol/L, glucose 12.6 mmol/L and urea 19.2 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 151 mmol/Lglucose 12.6 mmol/Lurea 19.2 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.08, PaCO₂ 42 mmHg (5.6 kPa), HCO₃⁻ 12 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.08PaCO₂ 42 mmHg (5.6 kPa)HCO₃⁻ 12 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows atrial flutter. How many flutter waves per QRS complex are there (the n of n:1 conduction)?
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
flutter waves per QRS =
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1asystole
2third-degree (complete) AV block
3sinus bradycardia
4junctional rhythm
15.Prioritization & delegationMedium
Which action helps prevent a catheter-associated urinary tract infection?
ALeaving the catheter in place longer than needed
BKeeping the drainage bag below the level of the bladder
CDisconnecting the bag every shift to empty it
DRaising the drainage bag above the bladder when walking
16.Prioritization & delegationHard
Which patient’s planned discharge should the nurse question?
AA patient with pneumonia who has been without fever for 48 hours on oral antibiotics
BA patient two days after surgery with a new heart rate of 112/min and a temperature of 38.4 °C
CA patient after a hernia repair who is passing urine and eating
DA patient with a stable cast who is walking safely with crutches
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Some warning signs, such as a fast heartbeat, may be masked
Why this is the answer
Beta-blockers can blunt adrenergic symptoms of hypoglycaemia such as palpitations and tremor. Sweating usually remains. Patients should check their glucose if they feel unwell and know their other warning signs.
Answer
B · Some warning signs, such as a fast heartbeat, may be masked
2.Med-surg: cardiovascular & respiratory
Answer: D · Circulation, sensation and movement of the hand, and the site
Why this is the answer
After radial access, the compression device and puncture site are checked for bleeding or haematoma, and the hand for colour, warmth, capillary refill, sensation and movement. Radial artery occlusion and forearm compartment syndrome are possible complications.
Answer
D · Circulation, sensation and movement of the hand, and the site
3.Med-surg: neuro, endocrine & renal
Answer: B · An expanding neck swelling with noisy breathing
Why this is the answer
A neck haematoma after carotid surgery can compress the airway quickly. It needs immediate senior help and may need the wound opened. Neurological checks for new stroke and cranial nerve damage are also part of routine care.
Answer
B · An expanding neck swelling with noisy breathing
4.Med-surg: neuro, endocrine & renal
Answer: C · Give IV antibiotics at once and start sepsis treatment
Why this is the answer
Meningococcal septicaemia can kill within hours. Antibiotics must not be delayed for a lumbar puncture or scan. Fluids and other sepsis care are started, and a lumbar puncture is often unsafe in a shocked patient.
Answer
C · Give IV antibiotics at once and start sepsis treatment
5.Med-surg: GI, perioperative & oncology
Answer: A · Long inflation can cause nerve and muscle damage
Why this is the answer
A tourniquet creates a bloodless field but causes limb ischaemia. Inflation time and pressure are recorded and the surgeon is told at set intervals, as long inflation can damage nerves and muscle.
Answer
A · Long inflation can cause nerve and muscle damage
6.Med-surg: GI, perioperative & oncology
Answer: D · An opioid-naive older patient with sleep apnoea who also takes a sedative
Why this is the answer
Risk factors include opioid-naive status, older age, obstructive sleep apnoea, obesity, renal or hepatic impairment, lung disease and concurrent sedatives (benzodiazepines, gabapentinoids). These patients need closer monitoring of sedation, respiratory rate and saturation, sometimes continuously.
Answer
D · An opioid-naive older patient with sleep apnoea who also takes a sedative
7.Clinical nursing
Answer: C · Protect the head, time the seizure and do not put anything in the mouth
Why this is the answer
Remove nearby hazards, cushion the head, note the time and do not restrain or put objects in the mouth. Once jerking stops, place the patient in the recovery position and check the airway.
Answer
C · Protect the head, time the seizure and do not put anything in the mouth
8.Clinical nursing
Answer: D · Lowering the sodium too fast can cause cerebral oedema
Why this is the answer
In chronic hypernatraemia, brain cells adapt by holding extra solutes. If sodium falls too quickly, water moves into brain cells and causes cerebral oedema, so correction is controlled.
Answer
D · Lowering the sodium too fast can cause cerebral oedema
9.Lab values & electrolytes
Answer: B · Liver function tests and platelet count
Why this is the answer
Valproate can cause liver toxicity and thrombocytopenia, so liver tests and the platelet count are monitored. It can also raise ammonia; confusion or vomiting should prompt an ammonia level.Checked against:Valproic Acid · StatPearls (NCBI Bookshelf) (2024)
Answer
B · Liver function tests and platelet count
10.Lab values & electrolytes
Answer: D · The diuretic is causing sodium and potassium loss
Why this is the answer
Thiazide diuretics commonly cause hyponatremia and hypokalemia, especially in older adults. The nurse reports the results, and the prescriber reviews the drug and electrolyte replacement.Checked against:Thiazide Diuretics · StatPearls (NCBI Bookshelf) (2025)
Answer
D · The diuretic is causing sodium and potassium loss
11.Arterial blood gas interpretation
Answer: Osm = 334 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·151 + 12.6 + 19.2 = 333.8 ≈ 334 mOsm/kg
Answer
Osm = 334 mOsm/kg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·12 + 8 = 26 → 24–28 mmHg
Compare
measured: 42 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: flutter waves per QRS = 3
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Flutter waves
F–F = 5 small boxes = 0.20 s → 1500 ÷ 5 = 300 per minute
QRS complexes
R–R = 15 small boxes = 0.60 s → 1500 ÷ 15 = 100 per minute
conduction ratio = 300 ÷ 100 = 3:1
Answer
flutter waves per QRS = 3
14.ECG rhythm strip interpretation
Answer: asystole
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: no countable ventricular rate.
2. Rhythm: none; an almost flat line.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: no QRS complexes.
Interpretation
asystole
Answer
asystole
A flat line is always checked: look at the patient, the leads and the gain, and view a second lead, because a loose electrode or fine VF can look like asystole.
15.Prioritization & delegation
Answer: B · Keeping the drainage bag below the level of the bladder
Why this is the answer
Keeping the bag below the bladder prevents backflow, and the closed system is not broken. Catheters are removed as soon as they are no longer needed.
Answer
B · Keeping the drainage bag below the level of the bladder
16.Prioritization & delegation
Answer: B · A patient two days after surgery with a new heart rate of 112/min and a temperature of 38.4 °C
Why this is the answer
A new fever and tachycardia after surgery can signal infection or another complication, so the nurse should assess and raise the concern before discharge. The other patients are stable and meeting expected goals.
Answer
B · A patient two days after surgery with a new heart rate of 112/min and a temperature of 38.4 °C