Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient's blood pressure is 120/60 mmHg. What is the approximate mean arterial pressure?
A90 mmHg
B60 mmHg
C100 mmHg
D80 mmHg
2.Med-surg: cardiovascular & respiratoryHard
Before the morning dose of digoxin, a patient's apical pulse is 54/min and they feel nauseated. What should the nurse do?
AGive the dose and an antiemetic, then recheck the pulse tomorrow
BGive the dose, because only a radial pulse counts
CWithhold the dose and report it, as toxicity is possible
DGive half the dose and recheck the pulse in an hour
3.Med-surg: neuro, endocrine & renalMedium
Which blood gas pattern is typical of acute kidney injury?
ALow pH and low bicarbonate
BHigh pH and low carbon dioxide
CLow pH and high carbon dioxide only
DHigh pH and high bicarbonate
4.Med-surg: neuro, endocrine & renalHard
Which nursing care is important for a patient receiving mannitol for raised intracranial pressure?
AGiving the drug orally with meals to reduce nausea
BStopping the fluid balance chart during treatment
CClose monitoring of urine output, sodium and osmolality
DClamping the catheter to keep fluid in the body
5.Med-surg: GI, perioperative & oncologyMedium
For how long are special precautions often taken with body fluids after many chemotherapy drugs?
AThey are never needed
BCommonly about 48 hours
COnly during the infusion
DFor a whole year
6.Med-surg: GI, perioperative & oncologyHard
A patient with diabetes has rapidly spreading redness around a small wound, severe pain out of proportion, fever and crackling under the skin. What should the nurse suspect?
AA healing venous ulcer
BA simple insect bite
CMild contact dermatitis
DNecrotising fasciitis
7.Clinical nursingMedium
What should a nurse do during a generalised tonic-clonic seizure?
APut a tongue depressor between the teeth so that the tongue is not bitten
BProtect the head, time the seizure and do not put anything in the mouth
CGive the patient a drink of water
DHold the limbs firmly to stop the jerking and prevent injury
8.Clinical nursingHard
Which nursing assessment best helps detect early deterioration in a patient after major surgery?
ARegular full sets of observations with an early warning score and trend review
BChecking the wound only at discharge
CAsking the patient only whether they feel well
DMeasuring temperature once a day
9.Lab values & electrolytesMedium
When should a patient with chronic kidney disease take a phosphate binder such as calcium acetate or sevelamer?
AOnly when the patient feels unwell
BWith meals
CAt bedtime on an empty stomach
DOnly once a week
10.Lab values & electrolytesHard
A patient receiving chemotherapy has a white cell count of 1.8 × 10³/µL with 20% neutrophils and 5% bands. What is the absolute neutrophil count (ANC)?
A450/µL
B1,800/µL
C360/µL
D4,500/µL
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 59 mmHg (7.9 kPa). Use the rule that in chronic respiratory acidosis HCO₃⁻ rises by 3.5 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a respiratory acidosis: pH 7.19, PaCO₂ 74 mmHg (9.9 kPa), HCO₃⁻ 27 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.19PaCO₂ 74 mmHg (9.9 kPa)HCO₃⁻ 27 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
Identify the rhythm on this lead II strip. Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1ventricular tachycardia
2ventricular fibrillation
3atrial flutter, 2:1 conduction
4atrial fibrillation
15.Prioritization & delegationMedium
A patient with asthma has two inhalers: a corticosteroid and salbutamol (albuterol). Which statement shows a need for further teaching?
A“I will rinse my mouth after using the steroid inhaler.”
B“I will carry my salbutamol inhaler with me.”
C“I will use my steroid inhaler every day, even when I feel well.”
D“I will use my steroid inhaler when I have a sudden attack.”
16.Prioritization & delegationHard
Which patient with cirrhosis should the nurse see first?
AVomiting bright red blood, heart rate 120/min
BLong-standing jaundice and itchy skin, asking for cream
CWants to talk about stopping drinking alcohol for good
DLarge ascites that is unchanged from yesterday
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: D · 80 mmHg
Why this is the answer
MAP ≈ diastolic + (systolic − diastolic) ÷ 3 = 60 + 60 ÷ 3 = 80 mmHg. The heart spends longer in diastole, so MAP is closer to the diastolic value. A MAP of at least about 65 mmHg is a common target for organ perfusion.
Answer
D · 80 mmHg
2.Med-surg: cardiovascular & respiratory
Answer: C · Withhold the dose and report it, as toxicity is possible
Why this is the answer
A common rule is to withhold digoxin and inform the prescriber if the apical pulse is below 60/min (or below the set parameter) or if there are toxic features such as nausea, vomiting, visual disturbance or a new arrhythmia. A digoxin level, ECG, potassium and renal function are usually checked. The nurse does not change a dose on their own initiative.
Answer
C · Withhold the dose and report it, as toxicity is possible
3.Med-surg: neuro, endocrine & renal
Answer: A · Low pH and low bicarbonate
Why this is the answer
Failing kidneys cannot excrete acid or regenerate bicarbonate, causing a metabolic acidosis with low pH and low bicarbonate. The patient may breathe faster to blow off CO2 as compensation.
Answer
A · Low pH and low bicarbonate
4.Med-surg: neuro, endocrine & renal
Answer: C · Close monitoring of urine output, sodium and osmolality
Why this is the answer
Mannitol draws water out of the brain into the blood and is excreted by the kidneys, causing a large diuresis. Monitoring for dehydration, hypotension, electrolyte disturbance and high osmolality is required, and a urinary catheter is usually needed.
Answer
C · Close monitoring of urine output, sodium and osmolality
5.Med-surg: GI, perioperative & oncology
Answer: B · Commonly about 48 hours
Why this is the answer
Many cytotoxic drugs are excreted in urine, faeces, vomit and other fluids for some time after administration. Local policies often require gloves and gowns for handling body fluids for about 48 hours, and longer for some drugs.
Answer
B · Commonly about 48 hours
6.Med-surg: GI, perioperative & oncology
Answer: D · Necrotising fasciitis
Why this is the answer
Necrotising soft tissue infection spreads rapidly along fascial planes and can cause septic shock. It is a surgical emergency needing urgent debridement, IV antibiotics and sepsis care.
Answer
D · Necrotising fasciitis
7.Clinical nursing
Answer: B · Protect the head, time the seizure and do not put anything in the mouth
Why this is the answer
Remove nearby hazards, cushion the head, note the time and do not restrain or put objects in the mouth. Once jerking stops, place the patient in the recovery position and check the airway.
Answer
B · Protect the head, time the seizure and do not put anything in the mouth
8.Clinical nursing
Answer: A · Regular full sets of observations with an early warning score and trend review
Why this is the answer
Track-and-trigger systems such as NEWS2 combine respiratory rate, SpO2, blood pressure, pulse, consciousness and temperature to identify deterioration early.
Answer
A · Regular full sets of observations with an early warning score and trend review
9.Lab values & electrolytes
Answer: B · With meals
Why this is the answer
Phosphate binders work in the gut by binding phosphate from food, so they are taken with meals. Taken between meals, they have little effect.
Answer
B · With meals
10.Lab values & electrolytes
Answer: A · 450/µL
Why this is the answer
ANC = 1,800 × (0.20 + 0.05) = 450/µL. A value below 500/µL is severe neutropenia with a high risk of serious infection, so neutropenic precautions and early reporting of fever are essential.Checked against:Blood Differential · MedlinePlus (NIH) (2024)
Answer
A · 450/µL
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 30.65 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|59 − 40| = 19 mmHg → 1.9 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 3.5·1.9 = 30.65 mmol/L
Answer
HCO₃⁻ = 30.65 mmol/L
12.Arterial blood gas interpretation
Answer: acute
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·3.4 = 27.4 mmol/L
chronic: 24 + 3.5·3.4 = 35.9 mmol/L
Compare
measured: 27 mmol/L → acute
Answer
acute
13.ECG rhythm strip interpretation
Answer: pause = 2.08 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
52 small boxes from R to R across the pause
Convert
pause = 52 × 0.04 s = 2.08 s
Compare with P–P
2.08 ÷ 0.88 ≈ 2.4 P–P cycles, not a whole number
Answer
pause = 2.08 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: ventricular tachycardia
Ventricular rhythms: ventricular tachycardia is a run of three or more wide (0.12 s or more) complexes in a row at more than 100/min, usually 150–250/min, regular, without related P waves. Ventricular fibrillation is a chaotic, irregular waveform with no identifiable P waves, QRS complexes or T waves and no countable rate. Asystole is an almost flat line with no ventricular activity; a flat line is always confirmed by checking the patient, the leads and the gain and a second lead. In resuscitation guidelines VF and pulseless VT are the shockable rhythms and asystole is not.
Five steps
1. Rate: R–R = 10 small boxes, 1500 ÷ 10 ≈ 150 per minute.
2. Rhythm: regular, every R–R is 0.40 s.
3. P waves: none identifiable.
4. PR interval: not measurable.
5. QRS: 0.16 s, wide (0.12 s or more).
Interpretation
ventricular tachycardia
Answer
ventricular tachycardia
In resuscitation guidelines VF and pulseless VT are the shockable rhythms. This is identification practice only.
15.Prioritization & delegation
Answer: D · “I will use my steroid inhaler when I have a sudden attack.”
Why this is the answer
Inhaled corticosteroids reduce inflammation over time and do not relieve an acute attack. Salbutamol (albuterol) is the quick-relief inhaler; rinsing after steroids helps prevent oral thrush.
Answer
D · “I will use my steroid inhaler when I have a sudden attack.”
16.Prioritization & delegation
Answer: A · Vomiting bright red blood, heart rate 120/min
Why this is the answer
Vomiting blood with a fast pulse suggests bleeding esophageal varices, which can quickly be fatal. The other findings are chronic or stable.