Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A chest drain water-seal chamber bubbles continuously, even when the patient is not coughing. What does this suggest?
AThe lung has fully re-expanded and the drain is ready to remove
BAn air leak from the lung or from the drainage system
CThe suction source has been switched off
DThe drain is blocked by a clot in the tubing
2.Med-surg: cardiovascular & respiratoryHard
A nurse is planning care for four patients. Which patient should be assessed first?
AA patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
BA patient with a venous ulcer due for a dressing change
CA patient with stable heart failure waiting for the daily weight
DA patient with controlled hypertension asking about salt
3.Med-surg: neuro, endocrine & renalMedium
Why is good blood pressure control important in chronic kidney disease?
AIt slows the decline in kidney function
BIt cures chronic kidney disease
CIt lowers the blood glucose
DIt raises the haemoglobin level in the blood
4.Med-surg: neuro, endocrine & renalHard
A patient with diabetes insipidus after head trauma needs hourly urine output measurement. Which task can be delegated to a trained healthcare assistant (nursing assistant)?
ADeciding whether to give the next desmopressin dose
BMeasuring hourly urine and reporting results above a set amount
CAssessing the patient's level of consciousness
DInterpreting the serum sodium results
5.Med-surg: GI, perioperative & oncologyMedium
Why is a pregnancy test often done before surgery in women who could be pregnant?
AAnaesthesia, drugs and some tests may harm a fetus
BPregnant women cannot sign consent forms
CIt is needed to calculate the anaesthetic drug dose
DPregnancy always makes surgery impossible
6.Med-surg: GI, perioperative & oncologyHard
After a high-voltage electrical injury, a patient's urine is dark red-brown. What does this suggest and what is the usual aim?
ANormal concentrated urine; restrict fluids
BMyoglobin from muscle damage; a higher urine output target
CA urinary infection; send a sample and wait for the result
DBleeding from the bladder; stop all fluids
7.Clinical nursingMedium
After thyroid surgery, a patient has tingling around the mouth and muscle cramps. Which electrolyte problem should be suspected?
AHyperkalaemia
BHypermagnesaemia
CHypocalcaemia
DHypernatraemia
8.Clinical nursingHard
An arterial blood gas shows a low PaO2 with a low or normal PaCO2. How is this classified?
ANormal blood gas
BMetabolic acidosis
CType 2 respiratory failure
DType 1 respiratory failure
9.Lab values & electrolytesMedium
A patient with hyponatremia from SIADH starts tolvaptan. Why is the serum sodium checked frequently in the first day?
AThe sodium always falls further
BThe drug lowers blood glucose sharply
CThe sodium can rise too quickly
DThe drug causes severe hyperkalemia
10.Lab values & electrolytesHard
A patient with diabetes and chronic kidney disease had a CT scan with IV contrast. Two days later, the creatinine has risen from 1.4 to 2.0 mg/dL (124 to 177 µmol/L). Which action is most appropriate?
ARestrict all fluids to protect the kidneys from more contrast
BIgnore it, because contrast never affects kidney function
CGive extra metformin, because the glucose rises after contrast
DReport it, monitor urine output and hold metformin until reviewed
11.Arterial blood gas interpretationMedium
Practice values: Na⁺ 145 mmol/L, glucose 25.3 mmol/L and urea 12.5 mmol/L. Calculate the serum osmolality Osm = 2·Na⁺ + glucose + urea to the nearest whole number.
Na⁺ 145 mmol/Lglucose 25.3 mmol/Lurea 12.5 mmol/L
Osm = mOsm/kg
12.Arterial blood gas interpretationHard
At sea level, a practice gas taken on 50% oxygen shows PaO₂ 91 mmHg (12.1 kPa) and PaCO₂ 36 mmHg (4.8 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1atrial fibrillation
2sinus rhythm with PVCs
3sinus arrhythmia
4junctional rhythm
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1third-degree (complete) AV block
2sinus bradycardia
3second-degree AV block type I (Wenckebach)
4second-degree AV block type II
15.Prioritization & delegationMedium
The day after a total thyroidectomy, a patient reports tingling around the mouth and in the fingers. What should the nurse do first?
AGive the patient’s routine oral iron supplement early
BEncourage deep breaths into a paper bag until it passes
CCheck for signs of low calcium and inform the provider
DReassure the patient that this is normal after neck surgery
16.Prioritization & delegationHard
Which assignment to an LPN/LVN is most appropriate?
AA patient with stable COPD who needs scheduled nebulized bronchodilators and oral medications
BA patient transferred from intensive care one hour ago
CA patient with new atrial fibrillation who has just started an IV diltiazem infusion
DA patient who needs discharge teaching for newly started warfarin
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · An air leak from the lung or from the drainage system
Why this is the answer
Intermittent bubbling on expiration or coughing is expected while a pneumothorax drains. Continuous bubbling suggests a persistent air leak from the lung (such as a bronchopleural fistula) or from a loose connection or a tube that has slipped out. Check the system from the patient downwards and report it.
Answer
B · An air leak from the lung or from the drainage system
2.Med-surg: cardiovascular & respiratory
Answer: A · A patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
Why this is the answer
A falling saturation with new drowsiness suggests acute respiratory failure, possibly with hypercapnia, and needs immediate assessment. The other patients are stable and their needs can wait briefly.
Answer
A · A patient with COPD whose SpO₂ fell from 90% to 83% with new drowsiness
3.Med-surg: neuro, endocrine & renal
Answer: A · It slows the decline in kidney function
Why this is the answer
Hypertension is both a cause and a result of CKD. Controlling it, often with an ACE inhibitor or ARB when albuminuria is present, slows the loss of kidney function and reduces cardiovascular risk.
Answer
A · It slows the decline in kidney function
4.Med-surg: neuro, endocrine & renal
Answer: B · Measuring hourly urine and reporting results above a set amount
Why this is the answer
Measuring and recording urine output with clear instructions on when to report is suitable for a trained assistant. Medication decisions, neurological assessment and interpreting results stay with the registered nurse.
Answer
B · Measuring hourly urine and reporting results above a set amount
5.Med-surg: GI, perioperative & oncology
Answer: A · Anaesthesia, drugs and some tests may harm a fetus
Why this is the answer
Unknown pregnancy can change the decision to operate, the timing, and the choice of drugs and X-rays. Testing is offered with consent, according to local policy.
Answer
A · Anaesthesia, drugs and some tests may harm a fetus
6.Med-surg: GI, perioperative & oncology
Answer: B · Myoglobin from muscle damage; a higher urine output target
Why this is the answer
Electrical injury can cause extensive muscle breakdown, releasing myoglobin that can damage the kidneys. A higher urine output target is set, with fluids titrated and creatine kinase and kidney function monitored.
Answer
B · Myoglobin from muscle damage; a higher urine output target
7.Clinical nursing
Answer: C · Hypocalcaemia
Why this is the answer
Damage to the parathyroid glands lowers calcium, causing perioral tingling, tetany and positive Chvostek or Trousseau signs.
Answer
C · Hypocalcaemia
8.Clinical nursing
Answer: D · Type 1 respiratory failure
Why this is the answer
Type 1 respiratory failure is hypoxaemia without hypercapnia, as in pneumonia or pulmonary embolism. Type 2 includes a raised PaCO2 from inadequate ventilation, as in COPD exacerbations.
Answer
D · Type 1 respiratory failure
9.Lab values & electrolytes
Answer: C · The sodium can rise too quickly
Why this is the answer
Tolvaptan blocks ADH receptors in the kidney, causing free water loss. Sodium can rise too fast, risking osmotic demyelination, so treatment is started in hospital with frequent sodium checks. Fluid restriction is usually avoided at the start.
Answer
C · The sodium can rise too quickly
10.Lab values & electrolytes
Answer: D · Report it, monitor urine output and hold metformin until reviewed
Why this is the answer
A creatinine rise of 0.3 mg/dL or more within 48 hours meets the criteria for AKI, and contrast is a recognized risk factor, especially in CKD and diabetes. The nurse reports it, monitors fluid balance and holds metformin until kidney function is reviewed, as metformin can accumulate.Checked against:Acute Kidney Injury · StatPearls (NCBI Bookshelf) (2026); Abdominal CT scan · MedlinePlus (NIH) (2024); Acute kidney failure · MedlinePlus (NIH) (2026)
Answer
D · Report it, monitor urine output and hold metformin until reviewed
11.Arterial blood gas interpretation
Answer: Osm = 328 mOsm/kg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Calculated osmolality
Osm = 2·145 + 25.3 + 12.5 = 327.8 ≈ 328 mOsm/kg
Answer
Osm = 328 mOsm/kg
12.Arterial blood gas interpretation
Answer: A–a gradient = 220.5 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
Alveolar oxygen
PAO₂ = 0.5·713 − 36/0.8 = 356.5 − 45 = 311.5 mmHg
Gradient
A–a = 311.5 − 91 = 220.5 mmHg
Answer
A–a gradient = 220.5 mmHg
13.ECG rhythm strip interpretation
Answer: atrial fibrillation
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: 8 QRS complexes in 6 s, × 10 = 80 per minute.
2. Rhythm: irregularly irregular, R–R from 0.50 to 1.00 s with no pattern.
3. P waves: none; the baseline shows small irregular fibrillatory waves.
4. PR interval: not measurable.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
atrial fibrillation
Answer
atrial fibrillation
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.84 s, 71 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: constant at 0.20 s in the conducted beats.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: C · Check for signs of low calcium and inform the provider
Why this is the answer
Damage to the parathyroid glands during thyroid surgery can cause hypocalcemia. Tingling, muscle cramps and a positive Chvostek or Trousseau sign need prompt reporting and calcium replacement as prescribed.
Answer
C · Check for signs of low calcium and inform the provider
16.Prioritization & delegation
Answer: A · A patient with stable COPD who needs scheduled nebulized bronchodilators and oral medications
Why this is the answer
A stable COPD patient with routine treatments has predictable care. A recent ICU transfer and a newly started IV rate-control infusion need RN assessment, and initial teaching about a new high-alert drug belongs to the RN.
Answer
A · A patient with stable COPD who needs scheduled nebulized bronchodilators and oral medications