Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
How does ezetimibe lower cholesterol?
AIt increases cholesterol loss in the urine
BIt reduces absorption of cholesterol from the gut
CIt blocks cholesterol production by enzymes in the liver
DIt dissolves plaques already in the arteries
2.Med-surg: cardiovascular & respiratoryHard
After a car crash, a patient is severely breathless with absent breath sounds on the right, a deviated trachea, distended neck veins and BP 76/40 mmHg. What is the immediate management?
AInsertion of a urinary catheter to monitor output
BUrgent needle or finger decompression of the right chest
CLying the patient flat with the legs raised
DA chest X-ray to confirm the diagnosis before any treatment
3.Med-surg: neuro, endocrine & renalMedium
A patient with a spinal cord injury can still feel a light touch around the anus. What does this show?
AThe sensation is only a spinal reflex and has no real meaning for recovery
BThe injury is incomplete, which suggests a better chance of recovery
CThe injury is complete, and recovery is not possible
DThe patient has an injury of the brain, not the cord
4.Med-surg: neuro, endocrine & renalHard
The night after hip surgery, an 84-year-old becomes suddenly confused and tries to pull out their IV line. What is the most appropriate first step?
AApply wrist restraints to protect the IV line
BTell the family that this is the start of dementia
CAsk for a strong sedative so that the patient can sleep
DLook for causes such as low oxygen, pain, retention or infection
5.Med-surg: GI, perioperative & oncologyMedium
After a spinal anaesthetic, which nursing check is particularly important?
APeak flow before and after each meal
BPupil reaction every five minutes for the next full day
CBlood glucose every 15 minutes overnight
DReturn of leg sensation and movement, and passing urine
6.Med-surg: GI, perioperative & oncologyHard
A patient with a severe flare of ulcerative colitis develops abdominal distension, fever and tachycardia, and the stool frequency has dropped. What should the nurse suspect?
AHaemorrhoids caused by diarrhoea
BThe flare is getting better
CSimple constipation from low intake
DToxic megacolon
7.Clinical nursingMedium
A patient is receiving enteral feeding through a nasogastric tube. How should they be positioned during feeding?
AWith the head of the bed raised to at least 30 degrees
BLying on the left side with the head down to help the feed drain
CLying completely flat
DIn any position, as long as the feed runs slowly
8.Clinical nursingHard
A nurse teaches a patient with diabetes about foot care. Which statement shows a need for further teaching?
A"I will wear well-fitting shoes."
B"I will walk barefoot at home to toughen my feet."
C"I will see the podiatrist about hard skin."
D"I will check my feet every day for cuts or blisters."
9.Lab values & electrolytesMedium
A patient takes low-dose methotrexate weekly for rheumatoid arthritis. Which laboratory tests are monitored regularly?
ATroponin, creatine kinase and myoglobin
BSerum lithium, sodium and urine specific gravity
CComplete blood count, liver tests and kidney function
DSerum amylase, lipase and blood ketones
10.Lab values & electrolytesHard
A patient has fatigue, weight loss, darkening of the skin and low blood pressure. Results: sodium 130 mEq/L, potassium 5.6 mEq/L. Which test pattern would confirm primary adrenal insufficiency (Addison disease)?
AHigh cortisol with a high ACTH
BLow cortisol with a high ACTH
CHigh cortisol with a low ACTH
DLow cortisol with a low ACTH
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 16 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 16 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic alkalosis with HCO₃⁻ 41 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 41 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
Interpret this lead II rhythm strip. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1junctional rhythm
2normal sinus rhythm
3sinus tachycardia
4first-degree AV block
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A stable adult with normal vital signs has a cut on the hand that needs sutures and nothing else. Which ESI level fits?
ALevel 4
BLevel 2
CLevel 5
DLevel 3
16.Prioritization & delegationHard
A patient has a chest drain for a pneumothorax. The nurse sees constant bubbling in the water-seal chamber. What does this most likely mean?
AThe drain is working normally and no action is needed
BThe suction is set too low and needs to be turned up
CAn air leak in the patient or the system that needs checking
DThe lung has fully re-expanded, so the drain is ready to come out
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · It reduces absorption of cholesterol from the gut
Why this is the answer
Ezetimibe blocks the intestinal cholesterol transporter (NPC1L1), so less dietary and biliary cholesterol is absorbed and LDL falls. It is often added to a statin. Statins act by inhibiting HMG-CoA reductase in the liver.
Answer
B · It reduces absorption of cholesterol from the gut
2.Med-surg: cardiovascular & respiratory
Answer: B · Urgent needle or finger decompression of the right chest
Why this is the answer
These signs indicate a tension pneumothorax, which causes obstructive shock. It is decompressed immediately (needle or finger thoracostomy) without waiting for an X-ray, followed by a chest drain. The nurse gives high-flow oxygen and calls for senior help.
Answer
B · Urgent needle or finger decompression of the right chest
3.Med-surg: neuro, endocrine & renal
Answer: B · The injury is incomplete, which suggests a better chance of recovery
Why this is the answer
Preserved sensation or movement in the lowest sacral segments (sacral sparing) means the injury is incomplete. Incomplete injuries have a much better chance of some functional recovery.
Answer
B · The injury is incomplete, which suggests a better chance of recovery
4.Med-surg: neuro, endocrine & renal
Answer: D · Look for causes such as low oxygen, pain, retention or infection
Why this is the answer
Acute confusion after surgery is often delirium. The nurse first looks for causes: hypoxia, pain, retention, constipation, infection, low glucose, dehydration and drugs. Sedation and restraints can make it worse and are a last resort.
Answer
D · Look for causes such as low oxygen, pain, retention or infection
5.Med-surg: GI, perioperative & oncology
Answer: D · Return of leg sensation and movement, and passing urine
Why this is the answer
The nurse monitors the level of the block, recovery of leg movement and sensation, BP and bladder function. Urinary retention is common, and early mobilisation is only safe once motor function returns.
Answer
D · Return of leg sensation and movement, and passing urine
6.Med-surg: GI, perioperative & oncology
Answer: D · Toxic megacolon
Why this is the answer
Toxic megacolon is dilatation of the inflamed colon with systemic toxicity and a high risk of perforation. Antimotility drugs and opioids are avoided, an abdominal X-ray is done and the surgical team is involved.
Answer
D · Toxic megacolon
7.Clinical nursing
Answer: A · With the head of the bed raised to at least 30 degrees
Why this is the answer
Keeping the head raised to at least 30–45° during feeding and for a period afterwards lowers the risk of aspiration pneumonia.
Answer
A · With the head of the bed raised to at least 30 degrees
8.Clinical nursing
Answer: B · "I will walk barefoot at home to toughen my feet."
Why this is the answer
Diabetic neuropathy and poor circulation mean small injuries can become ulcers. Patients should avoid walking barefoot, inspect their feet daily and get professional foot care.
Answer
B · "I will walk barefoot at home to toughen my feet."
9.Lab values & electrolytes
Answer: C · Complete blood count, liver tests and kidney function
Why this is the answer
Methotrexate can cause bone marrow suppression, liver toxicity and, as it is cleared by the kidneys, toxicity when kidney function falls. The CBC, liver tests and creatinine are checked regularly, and folic acid is usually given to reduce adverse effects.Checked against:Methotrexate · StatPearls (NCBI Bookshelf) (2024)
Answer
C · Complete blood count, liver tests and kidney function
10.Lab values & electrolytes
Answer: B · Low cortisol with a high ACTH
Why this is the answer
In primary adrenal insufficiency the adrenal glands fail, so cortisol is low and the pituitary responds with high ACTH, which also darkens the skin. Low cortisol with low ACTH suggests a pituitary cause. An ACTH stimulation test confirms the diagnosis.Checked against:Adrenocorticotropic Hormone (ACTH) · MedlinePlus (NIH) (2023); Cortisol Test · MedlinePlus (NIH) (2024)
Answer
B · Low cortisol with a high ACTH
11.Arterial blood gas interpretation
Answer: PaCO₂ = 32 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·16 + 8 = 32 mmHg
range: 30–34 mmHg
Answer
PaCO₂ = 32 mmHg
12.Arterial blood gas interpretation
Answer: PaCO₂ = 49.7 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·41 + 21 = 49.7 mmHg
Answer
PaCO₂ = 49.7 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: first-degree AV block
Rhythm criteria (lead II): sinus rhythm has an upright P wave before every QRS, a constant PR of 0.12–0.20 s and a narrow QRS: normal sinus rhythm at 60–100/min, sinus bradycardia below 60, sinus tachycardia above 100. Atrial fibrillation: no P waves, a fibrillatory baseline and an irregularly irregular R–R. Atrial flutter: sawtooth flutter waves at about 250–350/min with a fixed conduction ratio such as 2:1 or 4:1. First-degree AV block: sinus rhythm with a constant PR above 0.20 s. Junctional rhythm: narrow QRS at 40–60/min with absent or inverted P waves (PR below 0.12 s, or P after the QRS). A PVC is an early, wide (0.12 s or more), bizarre QRS without a P wave, with the T wave in the opposite direction and usually a full compensatory pause; in bigeminy every second beat is a PVC.
Five steps
1. Rate: R–R = 17 small boxes, 1500 ÷ 17 ≈ 88 per minute.
2. Rhythm: regular, every R–R is 0.68 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.28 s, constant, longer than 0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
Interpretation
first-degree AV block
Answer
first-degree AV block
14.ECG rhythm strip interpretation
Answer: rate
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 12 small boxes, 1500 ÷ 12 ≈ 125 per minute.
2. Rhythm: regular, every R–R is 0.48 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
rate → sinus tachycardia
Answer
rate
15.Prioritization & delegation
Answer: A · Level 4
Why this is the answer
For a stable patient, ESI levels 3 to 5 depend on the expected resources: two or more is level 3, one is level 4 and none is level 5. Simple suturing counts as one resource, so this is level 4.
Answer
A · Level 4
16.Prioritization & delegation
Answer: C · An air leak in the patient or the system that needs checking
Why this is the answer
Continuous bubbling in the water-seal chamber signals an air leak. The nurse checks the connections from the patient to the drain and reports a leak that cannot be fixed.
Answer
C · An air leak in the patient or the system that needs checking