Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Why is a raised serum lactate concerning in a patient with shock?
AIt shows only that the patient has eaten a large meal in the past hour
BIt confirms a bacterial infection is present
CIt suggests tissues are short of oxygen and using anaerobic metabolism
DIt means the kidneys are working harder than normal to clear fluid
2.Med-surg: cardiovascular & respiratoryHard
A ventilated patient suddenly desaturates to 82%. The cause is not obvious and the ventilator alarms are sounding. What should the nurse do first?
ADisconnect and hand-ventilate with 100% oxygen while calling for help
BIncrease the sedation and watch the monitor for the next half hour
CSilence the alarm and wait for the result of the next routine blood gas
DChange the ventilator settings to a higher rate
3.Med-surg: neuro, endocrine & renalMedium
How do DPP-4 inhibitors such as sitagliptin work?
AThey block glucose reabsorption in the kidney
BThey stop the gut from absorbing fat
CThey prolong the action of gut incretin hormones
DThey replace insulin that the pancreas cannot make
4.Med-surg: neuro, endocrine & renalHard
Which task for a stroke patient can a registered nurse safely delegate to a healthcare assistant (nursing assistant)?
AAssessing a new weakness the patient reports in the leg
BCarrying out the first bedside water swallow screen after admission
CRepositioning the patient every two hours as set out in the care plan
DTeaching the patient how to take a new anticoagulant
5.Med-surg: GI, perioperative & oncologyMedium
Which description fits a category (stage) 4 pressure ulcer?
AFull-thickness loss with exposed bone, tendon or muscle
BA shallow wound into the dermis only
CIntact skin with redness that does not blanch
DA blister filled with clear fluid over the heel or sacrum
6.Med-surg: GI, perioperative & oncologyHard
A patient with cirrhosis and ascites has a falling urine output and a rising creatinine. They have not received nephrotoxic drugs and are not dehydrated. Which complication is likely?
ANephrotic syndrome
BPolycystic kidney disease
CHepatorenal syndrome
DUrinary tract infection
7.Clinical nursingMedium
A nurse gives a patient analgesia for post-operative pain. What should be done next?
AGive a second analgesic straight away just in case
BAssume the pain has gone if the patient is quiet and has their eyes closed
CReassess the pain and any side effects once the drug has had time to work
DWait until the next shift before asking the patient about the pain
8.Clinical nursingHard
A postoperative patient has a heart rate of 115/min, temperature 38.6 °C, respiratory rate 26/min and blood pressure 85/50 mmHg despite a fluid bolus. What does this most likely indicate?
AMild dehydration only
BA normal inflammatory response in the first days after surgery
CAnxiety about discharge
DSeptic shock requiring urgent critical care review
9.Lab values & electrolytesMedium
A patient receiving chemotherapy has an ANC of 300/µL and a new temperature of 38.3 °C (100.9 °F). What should the nurse do first?
AGive acetaminophen (paracetamol) and recheck the temperature in 4 hours
BEncourage oral fluids and record the fever in the chart
CRemove extra blankets and offer a tepid sponge bath
DReport it at once so cultures and antibiotics start quickly
10.Lab values & electrolytesHard
A patient receiving IV magnesium sulfate has a respiratory rate of 9/min and absent patellar reflexes. After stopping the infusion, which medication should the nurse expect to give?
ACalcium gluconate
BPotassium chloride
CSodium bicarbonate
DProtamine sulfate
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 18 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 18 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a respiratory acidosis: pH 7.25, PaCO₂ 78 mmHg (10.4 kPa), HCO₃⁻ 33 mmol/L. Use the rules ‘HCO₃⁻ rises 1 mmol/L per 10 mmHg (acute) or 3.5 mmol/L per 10 mmHg (chronic)’ to classify it. Click your answer.
pH 7.25PaCO₂ 78 mmHg (10.4 kPa)HCO₃⁻ 33 mmol/L
1acute
2chronic
3acute on chronic
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1second-degree AV block type II
2third-degree (complete) AV block
3first-degree AV block
4second-degree AV block type I (Wenckebach)
15.Prioritization & delegationMedium
An anxious patient is breathing very fast and has tingling fingers. The blood gas shows pH 7.51 and PaCO₂ 29 mmHg (3.9 kPa). What should the nurse do first?
AEncourage the patient to breathe even faster
BGive oxygen at the highest flow and leave the room
CGive IV sodium bicarbonate as soon as it can be found
DStay with the patient and coach slow, calm breathing
16.Prioritization & delegationHard
Which assignment by the charge nurse should be changed?
AA nursing assistant is assigned to help several stable patients with their meals
BAn LPN/LVN is assigned to admit a new patient from the emergency department
CAn RN is assigned to a patient receiving a blood transfusion
DAn LPN/LVN is assigned to give oral medications to stable patients
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · It suggests tissues are short of oxygen and using anaerobic metabolism
Why this is the answer
When tissues are poorly perfused, cells switch to anaerobic metabolism and produce lactate. A raised lactate is a marker of tissue hypoperfusion and severity in sepsis and shock. Repeated measurements show whether treatment is working.
Answer
C · It suggests tissues are short of oxygen and using anaerobic metabolism
2.Med-surg: cardiovascular & respiratory
Answer: A · Disconnect and hand-ventilate with 100% oxygen while calling for help
Why this is the answer
When a ventilated patient deteriorates suddenly, bag-valve ventilation with 100% oxygen takes the ventilator out of the picture. The nurse then checks for displacement, obstruction, pneumothorax and equipment failure (often remembered as DOPE) and calls for senior help.
Answer
A · Disconnect and hand-ventilate with 100% oxygen while calling for help
3.Med-surg: neuro, endocrine & renal
Answer: C · They prolong the action of gut incretin hormones
Why this is the answer
DPP-4 inhibitors slow the breakdown of incretins such as GLP-1, so more insulin is released and less glucagon after meals. They rarely cause hypoglycaemia on their own and are weight-neutral.
Answer
C · They prolong the action of gut incretin hormones
4.Med-surg: neuro, endocrine & renal
Answer: C · Repositioning the patient every two hours as set out in the care plan
Why this is the answer
Repositioning to a set plan is a routine task that trained assistants can carry out. Swallow screening, assessing new symptoms and medication teaching need the nurse's clinical judgement and stay with the registered nurse.
Answer
C · Repositioning the patient every two hours as set out in the care plan
5.Med-surg: GI, perioperative & oncology
Answer: A · Full-thickness loss with exposed bone, tendon or muscle
Why this is the answer
Category 4 has full-thickness loss with exposed bone, tendon or muscle and often undermining or tunnelling. Category 3 reaches the fat but does not expose bone, tendon or muscle.
Answer
A · Full-thickness loss with exposed bone, tendon or muscle
6.Med-surg: GI, perioperative & oncology
Answer: C · Hepatorenal syndrome
Why this is the answer
In hepatorenal syndrome, severe vasodilation in advanced liver disease reduces kidney perfusion, causing kidney failure without another cause. It carries a poor prognosis and is managed by specialists, often with albumin and vasoconstrictors.
Answer
C · Hepatorenal syndrome
7.Clinical nursing
Answer: C · Reassess the pain and any side effects once the drug has had time to work
Why this is the answer
The effect of analgesia should be reassessed when it is expected to work, with side effects such as sedation and breathing checked. The result is documented and the plan adjusted.
Answer
C · Reassess the pain and any side effects once the drug has had time to work
8.Clinical nursing
Answer: D · Septic shock requiring urgent critical care review
Why this is the answer
Infection signs with hypotension not responding to fluid suggest septic shock. Vasopressors and critical care input are likely needed, along with antibiotics and source control.
Answer
D · Septic shock requiring urgent critical care review
9.Lab values & electrolytes
Answer: D · Report it at once so cultures and antibiotics start quickly
Why this is the answer
Neutropenic fever is a medical emergency, because infection can progress to sepsis rapidly without the usual signs of inflammation. Blood cultures are taken and broad-spectrum antibiotics are started promptly as prescribed.Checked against:Watch Out for Fever · CDC (2024); What You Need to Know: Neutropenia and Risk for Infection · CDC
Answer
D · Report it at once so cultures and antibiotics start quickly
10.Lab values & electrolytes
Answer: A · Calcium gluconate
Why this is the answer
Absent reflexes and slow breathing indicate magnesium toxicity. The infusion is stopped, the provider is called, the airway and breathing are supported, and IV calcium gluconate is given as prescribed to counteract magnesium.
Answer
A · Calcium gluconate
11.Arterial blood gas interpretation
Answer: PaCO₂ = 35 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·18 + 8 = 35 mmHg
range: 33–37 mmHg
Answer
PaCO₂ = 35 mmHg
12.Arterial blood gas interpretation
Answer: acute on chronic
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected HCO₃⁻
acute: 24 + 1·3.8 = 27.8 mmol/L
chronic: 24 + 3.5·3.8 = 37.3 mmol/L
Compare
measured: 33 mmol/L → acute on chronic
Answer
acute on chronic
13.ECG rhythm strip interpretation
Answer: pause = 2.16 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
54 small boxes from R to R across the pause
Convert
pause = 54 × 0.04 s = 2.16 s
Compare with P–P
2.16 ÷ 0.96 ≈ 2.3 P–P cycles, not a whole number
Answer
pause = 2.16 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: second-degree AV block type I (Wenckebach)
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 5 QRS complexes in 6 s, × 10 = 50 per minute.
2. Rhythm: regularly irregular, the QRS complexes come in groups separated by a pause (group beating).
3. P waves: upright and regular (P–P 0.88 s, 68 per minute); one P in every 4 is not followed by a QRS.
4. PR interval: lengthens 0.18 → 0.32 → 0.38 s, then a P wave is not conducted.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type I (Wenckebach)
Answer
second-degree AV block type I (Wenckebach)
15.Prioritization & delegation
Answer: D · Stay with the patient and coach slow, calm breathing
Why this is the answer
These results show respiratory alkalosis caused by hyperventilation. Calming the patient and coaching slower breathing lets carbon dioxide return to normal; the nurse also looks for physical causes.
Answer
D · Stay with the patient and coach slow, calm breathing
16.Prioritization & delegation
Answer: B · An LPN/LVN is assigned to admit a new patient from the emergency department
Why this is the answer
Admitting a new patient includes the initial assessment and plan of care, which belong to the RN. The other assignments match each staff member’s role.
Answer
B · An LPN/LVN is assigned to admit a new patient from the emergency department