Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient has a heart rate of 36/min with hypotension and dizziness. Which drug is usually the first choice?
AIntravenous adenosine
BIntravenous amiodarone
CIntravenous atropine
DOral bisoprolol
2.Med-surg: cardiovascular & respiratoryHard
A hypotensive patient has a temperature of 39.2 °C, warm flushed skin, a bounding pulse and a fast heart rate. Which type of shock is most likely?
ACardiogenic shock
BHypovolaemic shock from bleeding
CEarly septic (distributive) shock
DObstructive shock from tamponade
3.Med-surg: neuro, endocrine & renalMedium
A patient with primary adrenal insufficiency has a fever. What is the usual sick-day advice for steroid replacement?
AStop the steroid until the fever has settled
BKeep the usual dose and avoid drinking extra fluids for now
CIncrease the glucocorticoid dose, often doubling it
DHalve the dose to reduce the side effects
4.Med-surg: neuro, endocrine & renalHard
The nurse has four patients. Which one needs to be seen first?
AA patient with Parkinson's disease whose next dose is due in two hours
BA patient with hypothyroidism asking when to take levothyroxine
CA patient with stable CKD waiting for a renal diet review
DA patient on insulin for DKA whose potassium is now 2.9 mmol/L
5.Med-surg: GI, perioperative & oncologyMedium
Which instruction is important during bowel preparation for colonoscopy?
AEat a high-fibre meal the evening before the test
BTake the preparation only if the bowels have not opened
CAvoid all fluids for 24 hours before the test
DDrink plenty of clear fluids while taking the preparation
6.Med-surg: GI, perioperative & oncologyHard
Which history should most alert the nurse to a possible latex allergy before surgery?
AFeeling sick after eating shellfish once
BHay fever every spring since childhood
CA rash after taking amoxicillin as a child, with a family history of asthma
DItching with bananas, avocado and kiwi, and many operations
7.Clinical nursingMedium
A patient started on an ACE inhibitor develops a persistent dry cough. What is the likely cause?
AAsthma caused by a beta-blocker
BPulmonary embolism
CA recognised side effect of the ACE inhibitor
DAn allergic reaction to a recently given penicillin
8.Clinical nursingHard
A patient after abdominal surgery has not passed urine for eight hours, has lower abdominal discomfort and a palpable bladder. What is the most likely problem?
AAcute kidney injury with no urine production
BDehydration only
CAcute urinary retention
DUrinary tract infection without retention
9.Lab values & electrolytesMedium
A blood sample drawn just after a patient ate a fatty meal is reported as "lipemic." What does this mean for the results?
AThe sample shows the patient has diabetic ketoacidosis
BHigh fat in the sample may interfere with some test results
CThe sample was contaminated by an IV fluid with dextrose
DThe results are more accurate than in a fasting sample
10.Lab values & electrolytesHard
On the evening after surgery, a patient’s hemoglobin has fallen from 12.5 g/dL to 8.1 g/dL (125 to 81 g/L), and the heart rate is 118/min. What is the most likely problem?
ANormal dilution after surgery that needs no action
BDehydration
CAn improving condition
DBleeding
11.Arterial blood gas interpretationMedium
A practice arterial blood gas shows pH 7.20, PaCO₂ 40 mmHg (5.3 kPa) and HCO₃⁻ 15 mmol/L. The primary disorder is metabolic acidosis. How far is it compensated? Click your answer.
pH 7.20PaCO₂ 40 mmHg (5.3 kPa)HCO₃⁻ 15 mmol/L
1uncompensated
2partially compensated
3fully compensated
12.Arterial blood gas interpretationHard
A practice gas shows pH 7.31, PaCO₂ 31 mmHg (4.1 kPa) and HCO₃⁻ 15 mmol/L, with Na⁺ 145 and Cl⁻ 91 mmol/L. Use the anion gap and the delta ratio to click the best interpretation.
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
Which action by a nursing assistant needs the nurse to step in?
ALowering the bed to its lowest position and locking the wheels after care
BCleaning hands before entering the room
CTaking an oral temperature just after the patient drank cold water
DPutting the call light within the patient’s reach
16.Prioritization & delegationHard
A patient in acute mania paces constantly, has lost weight and will not sit down to eat. Which intervention is most helpful?
AOffer high-calorie finger foods and drinks the patient can take while moving
BLeave meals in the room and let the patient eat whenever and whatever they choose
CWait until the mania settles before worrying about nutrition
DInsist that the patient sits at the table until the meal is finished
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: C · Intravenous atropine
Why this is the answer
Atropine is an antimuscarinic that removes vagal tone and raises the heart rate. It is first-line for symptomatic bradycardia. If it fails, other options include a drug infusion or cardiac pacing. Adenosine, bisoprolol and amiodarone all slow conduction.
Answer
C · Intravenous atropine
2.Med-surg: cardiovascular & respiratory
Answer: C · Early septic (distributive) shock
Why this is the answer
Early septic shock often causes warm peripheries and bounding pulses because of widespread vasodilation. Cardiogenic, hypovolaemic and obstructive shock usually cause cool, clammy skin from vasoconstriction. Septic shock can later become "cold" as it progresses.
Answer
C · Early septic (distributive) shock
3.Med-surg: neuro, endocrine & renal
Answer: C · Increase the glucocorticoid dose, often doubling it
Why this is the answer
During illness, people on steroid replacement need more glucocorticoid. Sick-day rules usually advise doubling the dose during fever and using emergency injectable hydrocortisone or seeking urgent care if they vomit and cannot keep tablets down, to prevent adrenal crisis.
Answer
C · Increase the glucocorticoid dose, often doubling it
4.Med-surg: neuro, endocrine & renal
Answer: D · A patient on insulin for DKA whose potassium is now 2.9 mmol/L
Why this is the answer
Insulin drives potassium into cells, and a potassium of 2.9 mmol/L during DKA treatment can cause life-threatening arrhythmias. The insulin rate and potassium replacement need urgent review under the protocol. The other patients are stable.
Answer
D · A patient on insulin for DKA whose potassium is now 2.9 mmol/L
5.Med-surg: GI, perioperative & oncology
Answer: D · Drink plenty of clear fluids while taking the preparation
Why this is the answer
Bowel preparation causes profuse diarrhoea, which can lead to dehydration and electrolyte disturbance. Patients follow a low-residue diet, then clear fluids, and drink plenty of extra clear fluid.
Answer
D · Drink plenty of clear fluids while taking the preparation
6.Med-surg: GI, perioperative & oncology
Answer: D · Itching with bananas, avocado and kiwi, and many operations
Why this is the answer
Latex–fruit syndrome links latex allergy with foods such as banana, avocado, kiwi and chestnut. Repeated exposure, for example through many operations or catheters, also increases risk.
Answer
D · Itching with bananas, avocado and kiwi, and many operations
7.Clinical nursing
Answer: C · A recognised side effect of the ACE inhibitor
Why this is the answer
Dry cough is a common side effect of ACE inhibitors such as ramipril. An angiotensin II receptor blocker is often substituted.
Answer
C · A recognised side effect of the ACE inhibitor
8.Clinical nursing
Answer: C · Acute urinary retention
Why this is the answer
Anaesthesia, opioids and pain can cause retention. A bladder scan confirms residual volume; catheterisation is often needed.
Answer
C · Acute urinary retention
9.Lab values & electrolytes
Answer: B · High fat in the sample may interfere with some test results
Why this is the answer
Lipemia makes serum cloudy and can interfere with several laboratory methods, giving inaccurate results. The test may need to be repeated, often after a fast, according to laboratory advice.
Answer
B · High fat in the sample may interfere with some test results
10.Lab values & electrolytes
Answer: D · Bleeding
Why this is the answer
A fall of more than 4 g/dL with a fast heart rate suggests ongoing blood loss. The nurse assesses the wound and drains, monitors the vital signs and escalates urgently. Some dilution from IV fluids is common, but not this much, and not with tachycardia.Checked against:Hemoglobin Test · MedlinePlus (NIH) (2024)
Answer
D · Bleeding
11.Arterial blood gas interpretation
Answer: uncompensated
Reading a blood gas (ROME): first the pH: below 7.35 is acidaemia, above 7.45 alkalaemia. Then find the value that explains it. PaCO₂ (normal 35–45 mmHg, 4.7–6.0 kPa) is the respiratory part and moves Opposite to the pH in a respiratory disorder; HCO₃⁻ (normal 22–26 mmol/L) is the metabolic part and moves in the same direction as the pH (Respiratory Opposite, Metabolic Equal). The other value shows the compensation: normal means uncompensated; abnormal in the direction that pulls the pH back while the pH is still abnormal means partially compensated; a normal pH with both values abnormal means fully compensated. Ranges differ slightly between laboratories; these are practice values.
ROME, value by value
pH 7.20: acidaemia (below 7.35)
PaCO₂ 40 mmHg: normal (35–45)
HCO₃⁻ 15 mmol/L: low (22–26)
Compensation
Clinically, also check the expected compensation: Winter’s formula expects PaCO₂ 28.5–32.5 mmHg, so the measured 40 mmHg points to an additional respiratory acidosis (a mixed disorder). The answer above is the ROME exam classification.
uncompensated
Answer
uncompensated
12.Arterial blood gas interpretation
Answer: added metabolic alkalosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Anion gap
AG = 145 − (91 + 15) = 39
Delta ratio
(39 − 12)/(24 − 15) = 3
added metabolic alkalosis
Answer
added metabolic alkalosis
13.ECG rhythm strip interpretation
Answer: QTc = 0.427 s
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 9 × 0.04 = 0.36 s
RR = 15 × 0.04 = 0.60 s
Fridericia’s formula
QTc = 0.36/∛0.60 = 0.36/0.8434 = 0.427 s
Answer
QTc = 0.427 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (427 ms)
14.ECG rhythm strip interpretation
Answer: PR interval
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 18 small boxes, 1500 ÷ 18 ≈ 83 per minute.
2. Rhythm: regular, every R–R is 0.72 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.24 s, constant, longer than 0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
First abnormal step
PR interval → first-degree AV block
Answer
PR interval
15.Prioritization & delegation
Answer: C · Taking an oral temperature just after the patient drank cold water
Why this is the answer
A cold drink lowers mouth temperature for a short time, so the reading will be falsely low. The nurse should ask the assistant to wait before measuring. The other actions are correct.
Answer
C · Taking an oral temperature just after the patient drank cold water
16.Prioritization & delegation
Answer: A · Offer high-calorie finger foods and drinks the patient can take while moving
Why this is the answer
Patients in mania may be too active to sit and eat. Portable high-calorie foods and fluids help meet physiological needs, which are a priority.
Answer
A · Offer high-calorie finger foods and drinks the patient can take while moving