Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
Which energy-conservation advice is most useful for a patient with severe COPD?
ASit down for tasks such as washing and dressing, and pace activities
BHold the breath while lifting heavy objects
CAvoid any activity at all, staying in a chair to save their energy
DDo all the household tasks quickly in the morning to get them done
2.Med-surg: cardiovascular & respiratoryHard
A patient has sudden severe chest pain spreading to the back between the shoulder blades. Which finding most supports aortic dissection rather than myocardial infarction?
AA large difference in blood pressure between the arms
BPain that started at rest
CSweating, nausea and pallor that started with the pain
DA heart rate of 104/min and a respiratory rate of 22/min
3.Med-surg: neuro, endocrine & renalMedium
An 82-year-old taking apixaban fell three weeks ago. Since then their family has noticed increasing confusion and headaches. Which condition is most likely?
ANormal ageing with mild memory loss
BSubarachnoid haemorrhage from an aneurysm
CChronic subdural haematoma
DAcute extradural haematoma
4.Med-surg: neuro, endocrine & renalHard
On the first day after a kidney transplant, urine output suddenly falls from 200 mL/h to 10 mL/h. What should the nurse check first?
AThat the catheter is not blocked or kinked
BThe patient's temperature and pulse
CThe patient's blood glucose level
DWhether the patient has eaten
5.Med-surg: GI, perioperative & oncologyMedium
Which advice helps a patient with haemorrhoids?
ASit on the toilet for long periods to empty fully
BEat more fibre, drink enough fluid and avoid straining
CTake a codeine-based painkiller every day
DEat less fibre so that stools are smaller
6.Med-surg: GI, perioperative & oncologyHard
Which history should most alert the nurse to a possible latex allergy before surgery?
AFeeling sick after eating shellfish once
BHay fever every spring since childhood
CA rash after taking amoxicillin as a child, with a family history of asthma
DItching with bananas, avocado and kiwi, and many operations
7.Clinical nursingMedium
A blood transfusion is about to start. What is the most important safety check?
AChecking the patient's dietary preferences
BChecking the patient's weight only
CPositive patient identification matched to the blood component at the bedside
DWarming all blood in a microwave
8.Clinical nursingHard
A patient with severe sepsis starts bleeding from cannula sites and the gums, with a low platelet count and prolonged clotting times. What is most likely?
ADisseminated intravascular coagulation
BAn allergic reaction to the cannula
CHaemophilia A
DVitamin C deficiency
9.Lab values & electrolytesMedium
When should a blood specimen tube be labeled?
AIn the laboratory, by the staff who receive the unlabeled sample
BAt the nurses' station, after all samples for the shift are drawn
CAt the bedside, in the patient's presence, using two identifiers
DBefore entering the room, so tubes are ready for the next patients
10.Lab values & electrolytesHard
Four patients had a thyroidectomy earlier today. Which result should the nurse act on first?
AHemoglobin 12.1 g/dL (121 g/L) after surgery
BGlucose 145 mg/dL (8.0 mmol/L) after surgery
CSodium 136 mEq/L on IV fluids after surgery
DCalcium 7.2 mg/dL (1.8 mmol/L) with tingling lips
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 31 mmHg (4.1 kPa). Use the rule that in acute respiratory alkalosis HCO₃⁻ falls by 2 mmol/L for every 10 mmHg that PaCO₂ is below 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
At sea level, a practice gas taken on 35% oxygen shows PaO₂ 72 mmHg (9.6 kPa) and PaCO₂ 51 mmHg (6.8 kPa). Use PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 to find the A–a gradient.
Measure the QT interval and the R–R interval on this regular lead II strip, then calculate the rate-corrected QTc with Fridericia’s formula QTc = QT/∛RR (both in seconds). Give the answer in seconds to three decimals.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
QTc = s
14.ECG rhythm strip interpretationHard
A monitored patient is found unresponsive and not breathing normally, and no carotid pulse can be felt. The monitor shows this organised rhythm. What is this situation called? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1pulseless electrical activity (PEA)
2sinus bradycardia
3ventricular fibrillation
4asystole
15.Prioritization & delegationMedium
A patient’s urinary catheter has drained no urine for two hours, and the lower abdomen is swollen. What should the nurse do first?
ACheck the tubing for kinks or obstruction
BGive a prescribed diuretic straight away
CRemove the catheter and wait for the patient to void
DEncourage the patient to drink more water
16.Prioritization & delegationHard
A patient has a heart rate of 38/min, feels dizzy and has a blood pressure of 80/50 mmHg. Which drug is usually given first, as prescribed?
AMetoprolol
BAtropine
CDigoxin
DDiltiazem
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · Sit down for tasks such as washing and dressing, and pace activities
Why this is the answer
Planning and pacing, sitting for tasks, keeping frequently used items within reach and breathing out during effort reduce breathlessness. Complete inactivity worsens deconditioning, so activity is encouraged within limits.
Answer
A · Sit down for tasks such as washing and dressing, and pace activities
2.Med-surg: cardiovascular & respiratory
Answer: A · A large difference in blood pressure between the arms
Why this is the answer
A difference of more than about 20 mmHg in systolic pressure between the arms, a pulse deficit or a new aortic regurgitation murmur suggests dissection. Sweating, tachycardia and rest pain also occur in MI. Thrombolysis and anticoagulants could be disastrous in dissection, so the distinction matters.
Answer
A · A large difference in blood pressure between the arms
3.Med-surg: neuro, endocrine & renal
Answer: C · Chronic subdural haematoma
Why this is the answer
Older people have brain atrophy that stretches the bridging veins, and anticoagulants increase bleeding. A slow venous bleed can cause gradual confusion, headache or weakness over weeks. A CT scan is needed.
Answer
C · Chronic subdural haematoma
4.Med-surg: neuro, endocrine & renal
Answer: A · That the catheter is not blocked or kinked
Why this is the answer
A sudden drop in output after transplant may be caused by a blocked catheter, often from clots. The nurse checks the tubing and may flush the catheter per protocol, and then escalates urgently, because vascular thrombosis or rejection are also possible.
Answer
A · That the catheter is not blocked or kinked
5.Med-surg: GI, perioperative & oncology
Answer: B · Eat more fibre, drink enough fluid and avoid straining
Why this is the answer
Soft stools reduce straining and pressure on the anal cushions. Long sitting on the toilet and constipating drugs such as codeine should be avoided.
Answer
B · Eat more fibre, drink enough fluid and avoid straining
6.Med-surg: GI, perioperative & oncology
Answer: D · Itching with bananas, avocado and kiwi, and many operations
Why this is the answer
Latex–fruit syndrome links latex allergy with foods such as banana, avocado, kiwi and chestnut. Repeated exposure, for example through many operations or catheters, also increases risk.
Answer
D · Itching with bananas, avocado and kiwi, and many operations
7.Clinical nursing
Answer: C · Positive patient identification matched to the blood component at the bedside
Why this is the answer
The patient's identity on the wristband is checked against the compatibility label and prescription at the bedside. Baseline observations are taken before starting.
Answer
C · Positive patient identification matched to the blood component at the bedside
8.Clinical nursing
Answer: A · Disseminated intravascular coagulation
Why this is the answer
In DIC, widespread activation of clotting consumes platelets and clotting factors, causing both small clots and bleeding. Treating the underlying cause and replacing blood products as needed are key.
Answer
A · Disseminated intravascular coagulation
9.Lab values & electrolytes
Answer: C · At the bedside, in the patient's presence, using two identifiers
Why this is the answer
Specimens are labeled immediately after collection, at the bedside, after checking two patient identifiers such as name and date of birth. Pre-labeling or labeling away from the patient can put the wrong patient's name on the sample, which can lead to harmful decisions.
Answer
C · At the bedside, in the patient's presence, using two identifiers
10.Lab values & electrolytes
Answer: D · Calcium 7.2 mg/dL (1.8 mmol/L) with tingling lips
Why this is the answer
Hypocalcemia after thyroid surgery, from parathyroid injury, can progress to tetany and laryngospasm. Tingling lips are an early sign, so the nurse assesses the airway and Chvostek and Trousseau signs and reports at once. The other results are expected after surgery.Checked against:Calcium Blood Test · MedlinePlus (NIH) (2024)
Answer
D · Calcium 7.2 mg/dL (1.8 mmol/L) with tingling lips
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 22.2 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|31 − 40| = 9 mmHg → 0.9 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 − 2·0.9 = 22.2 mmol/L
Answer
HCO₃⁻ = 22.2 mmol/L
12.Arterial blood gas interpretation
Answer: A–a gradient = 113.8 mmHg
Derived values: calculated serum osmolality is 2·Na⁺ + glucose + urea with all values in mmol/L (2·Na⁺ + glucose/18 + BUN/2.8 with glucose and BUN in mg/dL); normal is about 275–295 mOsm/kg. The P/F ratio is PaO₂ divided by FiO₂ as a fraction. The alveolar oxygen pressure is PAO₂ = FiO₂·(760 − 47) − PaCO₂/0.8 mmHg at sea level, and the A–a gradient is PAO₂ − PaO₂.
QT and QTc: the QT interval runs from the start of the QRS complex to the end of the T wave. It shortens as the heart rate rises, so it is corrected for rate with the R–R interval in seconds: Bazett QTc = QT/√RR and Fridericia QTc = QT/∛RR. Bazett is the formula most textbooks use; it over-corrects at fast rates, where Fridericia is preferred. Limits differ between references: a QTc above about 0.45 s in men or 0.46 s in women is usually called prolonged, and above 0.50 s markedly prolonged.
Measure
QT = 10 × 0.04 = 0.40 s
RR = 21 × 0.04 = 0.84 s
Fridericia’s formula
QTc = 0.40/∛0.84 = 0.40/0.9435 = 0.424 s
Answer
QTc = 0.424 s
Within the usual limits (about 0.45 s for men, 0.46 s for women). (424 ms)
14.ECG rhythm strip interpretation
Answer: pulseless electrical activity (PEA)
Pulseless electrical activity (PEA): PEA cannot be seen on a strip. The monitor shows organised electrical activity (a rhythm other than VF, VT or asystole) but the patient has no palpable pulse, so it is recognised by checking the patient. In adult resuscitation guidelines PEA and asystole are the non-shockable cardiac arrest rhythms: high-quality CPR, epinephrine as soon as possible and a search for reversible causes (the Hs and Ts, such as hypovolaemia, hypoxia, tension pneumothorax and cardiac tamponade). VF and pulseless VT are the shockable rhythms.
What the strip shows
1. Rate: R–R = 36 small boxes, 1500 ÷ 36 ≈ 42 per minute.
2. Rhythm: regular, every R–R is 1.44 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.14 s, constant, within 0.12–0.20 s.
5. QRS: 0.08 s, narrow (below 0.12 s).
sinus bradycardia
What the patient shows
no pulse despite organised electrical activity: pulseless electrical activity (PEA), a non-shockable cardiac arrest rhythm
Answer
pulseless electrical activity (PEA)
Answer
pulseless electrical activity (PEA)
PEA is recognised at the bedside, never from the strip alone. This is exam practice, not clinical guidance.
15.Prioritization & delegation
Answer: A · Check the tubing for kinks or obstruction
Why this is the answer
Sudden lack of drainage with a full bladder usually means a kinked or blocked catheter. The nurse checks the tubing and position first, then follows the policy for irrigation or replacement.
Answer
A · Check the tubing for kinks or obstruction
16.Prioritization & delegation
Answer: B · Atropine
Why this is the answer
Atropine is the first-line drug for symptomatic bradycardia. Metoprolol, digoxin and diltiazem slow the heart and would make things worse; pacing may be needed if atropine does not work.