Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient on furosemide has a serum potassium of 3.0 mmol/L (3.0 mEq/L). Which symptoms may this cause?
ASevere headache and a stiff neck
BMuscle weakness, cramps and an irregular pulse
CTingling around the lips and painful spasm of the hands
DFacial flushing, fever and a skin rash
2.Med-surg: cardiovascular & respiratoryHard
A patient with heart failure on a 1.5 L/day fluid restriction complains of severe thirst. Which measure is most appropriate?
ANo fluids at all until the next morning's weight
BMouth care, counted ice chips and fluids spread through the day
CSalty snacks to stimulate saliva and relieve dryness
DUnlimited water, because thirst must always be satisfied
3.Med-surg: neuro, endocrine & renalMedium
A patient wakes up with stroke symptoms. They went to bed well at 23:00 and woke at 06:30. Which time is used as the time of onset?
A06:30, when the symptoms were first noticed
B23:00, when they were last known to be well
CThe time of arrival at the hospital
DThe time the CT scan was performed
4.Med-surg: neuro, endocrine & renalHard
A man with chronic urinary retention is catheterised. Over the next hours he passes very large volumes of urine. What is the main nursing concern?
AA rise in blood glucose from the urine
BRupture of the bladder from the catheter
CA urinary infection caused by the high flow of urine
DFluid and electrolyte loss from post-obstructive diuresis
5.Med-surg: GI, perioperative & oncologyMedium
Which measure helps reduce the risk of delirium in an older surgical patient?
AGiving a sleeping tablet every night
BMaking sure they have their glasses and hearing aids
CKeeping the room dark during the day
DMoving them to a new bed space each night to reduce boredom
6.Med-surg: GI, perioperative & oncologyHard
Four patients from a house fire arrive in the emergency department. Which should the nurse assess first?
AA blistered forearm burn and a small cut on the knee
BCircumferential chest burns, with breathing becoming shallow and laboured
CPartial-thickness burns to both legs, with pain rated 8/10
DRedness on the backs of both hands, and very anxious
7.Clinical nursingMedium
What is the first-line drug treatment for anaphylaxis?
AOral antihistamine such as cetirizine
BInhaled steroid
CIntramuscular adrenaline
DIntravenous paracetamol
8.Clinical nursingHard
A patient has new facial weakness. Which feature suggests a stroke rather than Bell's palsy?
AThe patient has pain behind the ear
BThe forehead can still be wrinkled on the affected side
CThe whole of one side of the face, including the forehead, is weak
DThe patient has had a recent cold
9.Lab values & electrolytesMedium
A patient takes low-dose methotrexate weekly for rheumatoid arthritis. Which laboratory tests are monitored regularly?
AComplete blood count, liver tests and kidney function
BTroponin, creatine kinase and myoglobin
CSerum amylase, lipase and blood ketones
DSerum lithium, sodium and urine specific gravity
10.Lab values & electrolytesHard
Three days after starting haloperidol, a patient has a temperature of 40 °C, severe muscle rigidity and confusion. Which laboratory result would the nurse expect?
AA very low serum sodium
BA very low white cell count
CA very high creatine kinase (CK)
DA very high serum lithium
11.Arterial blood gas interpretationMedium
A practice gas shows a metabolic acidosis with HCO₃⁻ 16 mmol/L. Use Winter’s formula to find the expected PaCO₂ (the centre of the range) in mmHg.
HCO₃⁻ 16 mmol/L
PaCO₂ = mmHg
12.Arterial blood gas interpretationHard
A practice gas shows a metabolic acidosis: pH 7.09, PaCO₂ 31 mmHg (4.1 kPa), HCO₃⁻ 9 mmol/L. Compare the measured PaCO₂ with Winter’s formula. Click your interpretation.
pH 7.09PaCO₂ 31 mmHg (4.1 kPa)HCO₃⁻ 9 mmol/L
1appropriate compensation
2added respiratory acidosis
3added respiratory alkalosis
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
This lead II strip shows a conduction problem between the atria and the ventricles. Which rhythm is it? Click your answer.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1first-degree AV block
2third-degree (complete) AV block
3second-degree AV block type II
4second-degree AV block type I (Wenckebach)
15.Prioritization & delegationMedium
A patient’s urinary catheter has drained no urine for two hours, and the lower abdomen is swollen. What should the nurse do first?
ACheck the tubing for kinks or obstruction
BEncourage the patient to drink more water
CRemove the catheter and wait for the patient to void
DGive a prescribed diuretic straight away
16.Prioritization & delegationHard
After a vaginal birth, the uterus is firm and central, but bright red blood keeps trickling steadily. What should the nurse suspect?
ANormal lochia for the first hour
BA tear in the birth canal or cervix
CA full bladder pushing the uterus aside
DUterine atony that needs more massage
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: B · Muscle weakness, cramps and an irregular pulse
Why this is the answer
The adult reference range is about 3.5–5.0 mmol/L, so 3.0 mmol/L is low. Hypokalaemia causes weakness, cramps, constipation and arrhythmias, with flattened T waves and U waves on the ECG. Tingling lips and hand spasm suggest low calcium.
Answer
B · Muscle weakness, cramps and an irregular pulse
2.Med-surg: cardiovascular & respiratory
Answer: B · Mouth care, counted ice chips and fluids spread through the day
Why this is the answer
Spreading fluids through the day, using small cups, sucking ice chips (counted in the total), sugar-free gum and regular mouth care help patients tolerate fluid restriction. Salty foods increase thirst and fluid retention.
Answer
B · Mouth care, counted ice chips and fluids spread through the day
3.Med-surg: neuro, endocrine & renal
Answer: B · 23:00, when they were last known to be well
Why this is the answer
For "wake-up strokes", onset is taken as the time the patient was last known well, because the stroke could have happened at any point since then. This often places the patient outside the standard thrombolysis window, although advanced imaging can sometimes identify patients who may still benefit.
Answer
B · 23:00, when they were last known to be well
4.Med-surg: neuro, endocrine & renal
Answer: D · Fluid and electrolyte loss from post-obstructive diuresis
Why this is the answer
After relief of chronic obstruction, the kidneys may pass large volumes of urine and salt. Hypovolaemia and electrolyte problems can follow. Strict fluid balance, blood pressure checks and electrolyte monitoring are needed.
Answer
D · Fluid and electrolyte loss from post-obstructive diuresis
5.Med-surg: GI, perioperative & oncology
Answer: B · Making sure they have their glasses and hearing aids
Why this is the answer
Delirium prevention includes using glasses and hearing aids, orientation, good sleep, hydration, nutrition, early mobilisation, pain control, avoiding unnecessary sedatives and involving family.
Answer
B · Making sure they have their glasses and hearing aids
6.Med-surg: GI, perioperative & oncology
Answer: B · Circumferential chest burns, with breathing becoming shallow and laboured
Why this is the answer
Circumferential full-thickness burns of the chest form rigid eschar that restricts chest expansion and can cause respiratory failure. This patient needs immediate breathing assessment, senior help and possibly urgent escharotomy. The others need care but are not immediately life-threatening.
Answer
B · Circumferential chest burns, with breathing becoming shallow and laboured
7.Clinical nursing
Answer: C · Intramuscular adrenaline
Why this is the answer
Adrenaline IM into the thigh (for adults typically 0.5 mg, i.e. 0.5 mL of 1 mg/mL; US guidance 0.3–0.5 mg) is first line, repeated after 5 minutes if needed. Antihistamines and steroids are not first-line treatments.
Answer
C · Intramuscular adrenaline
8.Clinical nursing
Answer: B · The forehead can still be wrinkled on the affected side
Why this is the answer
In a stroke (upper motor neurone lesion), the forehead is usually spared because it has bilateral cortical supply. Bell's palsy (lower motor neurone) weakens the whole side, including the forehead.
Answer
B · The forehead can still be wrinkled on the affected side
9.Lab values & electrolytes
Answer: A · Complete blood count, liver tests and kidney function
Why this is the answer
Methotrexate can cause bone marrow suppression, liver toxicity and, as it is cleared by the kidneys, toxicity when kidney function falls. The CBC, liver tests and creatinine are checked regularly, and folic acid is usually given to reduce adverse effects.Checked against:Methotrexate · StatPearls (NCBI Bookshelf) (2024)
Answer
A · Complete blood count, liver tests and kidney function
10.Lab values & electrolytes
Answer: C · A very high creatine kinase (CK)
Why this is the answer
These signs suggest neuroleptic malignant syndrome, a medical emergency. Muscle rigidity releases CK, often to very high levels, and the white count is often raised. Myoglobin can damage the kidneys. The antipsychotic is stopped and supportive care is started.
Answer
C · A very high creatine kinase (CK)
11.Arterial blood gas interpretation
Answer: PaCO₂ = 32 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Winter’s formula
PaCO₂ = 1.5·16 + 8 = 32 mmHg
range: 30–34 mmHg
Answer
PaCO₂ = 32 mmHg
12.Arterial blood gas interpretation
Answer: added respiratory acidosis
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
1.5·9 + 8 = 21.5 → 19.5–23.5 mmHg
Compare
measured: 31 mmHg → added respiratory acidosis
Answer
added respiratory acidosis
13.ECG rhythm strip interpretation
Answer: pause = 2.16 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
54 small boxes from R to R across the pause
Convert
pause = 54 × 0.04 s = 2.16 s
Compare with P–P
2.16 ÷ 0.88 ≈ 2.5 P–P cycles, not a whole number
Answer
pause = 2.16 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: second-degree AV block type II
AV blocks: march out the P waves and check which ones are followed by a QRS. First-degree: every P conducted, PR constant and above 0.20 s. Second-degree type I (Mobitz I, Wenckebach): the PR lengthens from beat to beat until one P wave is not conducted, then the cycle starts again (group beating). Second-degree type II (Mobitz II): the PR of the conducted beats stays constant, and P waves are suddenly not conducted; the QRS is often wide. Third-degree (complete) block: P waves and QRS complexes are each regular but independent, the PR varies at random and the atrial rate is faster than the escape rate (junctional 40–60/min with a narrow QRS, ventricular 20–40/min with a wide QRS). A 2:1 block cannot be called type I or type II from one strip.
Five steps
1. Rate: 4 QRS complexes in 6 s, × 10 = 40 per minute.
2. Rhythm: the P waves are regular; R–R is regular except for a long pause where a QRS is missing.
3. P waves: upright and regular (P–P 0.92 s, 65 per minute); one P in every 3 is not followed by a QRS.
4. PR interval: constant at 0.16 s in the conducted beats.
5. QRS: 0.08 s, narrow (below 0.12 s).
Interpretation
second-degree AV block type II
Answer
second-degree AV block type II
Type II and third-degree blocks are the ones that can suddenly progress, so textbooks rank them as more serious than type I.
15.Prioritization & delegation
Answer: A · Check the tubing for kinks or obstruction
Why this is the answer
Sudden lack of drainage with a full bladder usually means a kinked or blocked catheter. The nurse checks the tubing and position first, then follows the policy for irrigation or replacement.
Answer
A · Check the tubing for kinks or obstruction
16.Prioritization & delegation
Answer: B · A tear in the birth canal or cervix
Why this is the answer
Continuous bright red bleeding with a firm uterus suggests a laceration of the cervix, vagina or perineum. The nurse reports it so it can be found and repaired.