Read the pH: below 7.35 is acidosis, above 7.45 alkalosis.
Find the value that explains it: PaCO₂ moving opposite to the pH is respiratory, HCO₃⁻ moving with the pH is metabolic.
Look at the other value: normal means uncompensated, abnormal in the compensating direction means partial compensation, and a normal pH with both abnormal means full compensation.
In a metabolic acidosis, compare PaCO₂ with Winter’s formula, 1.5·HCO₃⁻ + 8 ± 2, and calculate the anion gap Na⁺ − (Cl⁻ + HCO₃⁻).
Check a high anion gap with the delta ratio and, when albumin is low, with the corrected gap.
ECG rhythm strip interpretation
Paper (25 mm/s, 10 mm/mV)
1 small box = 0.04 s, 1 large box = 0.20 s, 10 mm = 1 mV
Heart rate, regular rhythm
300 ÷ large boxes = 1500 ÷ small boxes = 60 ÷ RR (s)
Heart rate, irregular rhythm
QRS complexes in 6 s × 10
Normal PR interval
0.12–0.20 s
Normal QRS duration
< 0.12 s
QTc (Bazett)
QT/√RR
QTc (Fridericia)
QT/∛RR
QTc (Framingham)
QT + 154·(1 − RR)
Sinus rates
bradycardia < 60, normal 60–100, tachycardia > 100 /min
Escape rates
junctional 40–60, ventricular 20–40 /min
Fast rhythms
SVT 150–250 /min (narrow), VT > 100 /min (wide)
Method
Rate: for a regular rhythm divide 300 by the large boxes or 1500 by the small boxes between two R waves; for an irregular rhythm count the QRS complexes in 6 seconds and multiply by 10.
Rhythm: compare the R–R intervals. Equal is regular; a repeating pattern is regularly irregular; no pattern at all is irregularly irregular.
P waves: is there an upright P wave in lead II before every QRS, all alike? Look for fibrillatory or sawtooth waves, inverted P waves and P waves without a QRS.
PR interval: from the start of P to the start of the QRS, normally 0.12–0.20 s and constant. Watch whether it lengthens, stays fixed before a dropped beat, or varies at random.
QRS duration: below 0.12 s is narrow; 0.12 s or more is wide. Then name the rhythm, and for the QT use QTc = QT/√RR (Bazett) with times in seconds.
Prioritization & delegation
Method
Ask what will harm the patient soonest if nothing is done.
Apply ABC (C-A-B in cardiac arrest), then Maslow: physiological needs before safety, safety before psychological needs.
Compare the options: acute before chronic, unstable before stable, unexpected before expected, systemic before local, and check each finding against the patient’s baseline.
Assess before you act unless it is an emergency; then choose the step the others depend on.
For delegation, check the five rights: task, circumstance, person, directions and supervision. Assessment, teaching and evaluation stay with the RN.
2Practice problems
1.Med-surg: cardiovascular & respiratoryMedium
A patient with COPD is prescribed long-term oxygen therapy. How many hours a day is it usually needed to improve survival?
AAt least 15 hours a day
BAbout one hour each morning
COnly during meals
DOnly when walking outside
2.Med-surg: cardiovascular & respiratoryHard
A patient with severe sepsis becomes increasingly breathless over 24 hours. SpO₂ stays low despite high-flow oxygen, and the chest X-ray shows bilateral infiltrates. The heart function is normal. Which condition is most likely?
ASpontaneous pneumothorax
BAcute left ventricular failure after an MI
CAcute respiratory distress syndrome
DAn acute asthma attack
3.Med-surg: neuro, endocrine & renalMedium
A patient receives phenytoin through a nasogastric tube along with continuous enteral feed. Which issue should the nurse know about?
APhenytoin must be crushed and mixed into the feed bag
BThe feed can reduce phenytoin absorption, so the feed is often paused around the dose
CPhenytoin makes the feed curdle, so the two must never be used in one patient
DThe feed increases phenytoin levels and causes toxicity within hours
4.Med-surg: neuro, endocrine & renalHard
After a total thyroidectomy, a patient becomes anxious with stridor and a tense swelling in the neck. What should the nurse do first?
AApply an ice pack to the neck and lie the patient flat
BGive analgesia and reassess the swelling again in an hour
CAsk the patient to talk as much as possible to test the voice
DCall for emergency help: a haematoma may compress the airway
5.Med-surg: GI, perioperative & oncologyMedium
How should a patient with facial burns usually be positioned?
ALying flat with the head lower than the feet
BIn any position that keeps the face covered
CLying face down on the pillow to protect the airway
DWith the head of the bed raised to reduce swelling
6.Med-surg: GI, perioperative & oncologyHard
An hour after a line flush, a patient receiving parenteral nutrition has rigors and a temperature of 39.1 °C. What should the nurse suspect and do?
AA normal reaction; give paracetamol and continue the infusion
BLow blood glucose; give a sugary drink
CFluid overload; reduce the infusion rate only
DLine infection; escalate and take blood cultures
7.Clinical nursingMedium
Which oxygen device delivers a precise, fixed concentration of oxygen?
AVenturi mask
BNon-rebreathe mask
CSimple face mask
DNasal cannula
8.Clinical nursingHard
A patient with new fast atrial fibrillation has chest pain, a blood pressure of 75/40 mmHg and is confused. What does this indicate?
AAnxiety about the new diagnosis that will settle with reassurance and rest alone
CA normal response to atrial fibrillation needing no action
DA stable rhythm that can safely be reviewed at the next routine ward round
9.Lab values & electrolytesMedium
A urine culture is ordered for a patient with an indwelling urinary catheter. How should the nurse collect the sample?
ARemove the catheter and culture the catheter tip
BDisconnect the catheter from the tubing and let it drain
CAspirate from the sampling port with a sterile syringe
DPour urine from the drainage bag into a sterile cup
10.Lab values & electrolytesHard
Three days after starting haloperidol, a patient has a temperature of 40 °C, severe muscle rigidity and confusion. Which laboratory result would the nurse expect?
AA very high creatine kinase (CK)
BA very low serum sodium
CA very high serum lithium
DA very low white cell count
11.Arterial blood gas interpretationMedium
A practice gas shows PaCO₂ 70 mmHg (9.3 kPa). Use the rule that in acute respiratory acidosis HCO₃⁻ rises by 1 mmol/L for every 10 mmHg that PaCO₂ is above 40, starting from HCO₃⁻ 24 mmol/L, to find the expected HCO₃⁻.
A practice gas shows a metabolic alkalosis with HCO₃⁻ 46 mmol/L. Use expected PaCO₂ = 0.7·HCO₃⁻ + 21 to find the expected PaCO₂.
HCO₃⁻ 46 mmol/L
PaCO₂ = mmHg
13.ECG rhythm strip interpretationMedium
This lead II strip shows sinus rhythm with one pause. Measure the pause, the R–R interval across it, in seconds.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
pause = s
14.ECG rhythm strip interpretationHard
Interpret this lead II strip with the five steps in order: rate, rhythm, P waves, PR interval, QRS duration. At which step do you find the first abnormal finding? Click it.
lead II, 25 mm/s, 10 mm/mV1 small box = 0.04 s, 1 large box = 0.20 sstrip length 6 s
1rate
2rhythm
3P waves
4PR interval
5QRS duration
15.Prioritization & delegationMedium
A patient has a new plaster cast that is still drying. How should the nurse handle it?
ABy resting it directly on a hard surface
BWith the fingertips, pressing firmly to test it
CWith the palms of the hands, not the fingertips
DBy covering it tightly with a plastic sheet
16.Prioritization & delegationHard
Which finding after a laparoscopic cholecystectomy is expected and needs only reassurance and comfort measures?
ARight shoulder pain from the gas used during surgery
BA heart rate of 125/min with a falling blood pressure
CIncreasing abdominal pain with a temperature of 39 °C
DYellow skin with dark urine on the second day
3Solutions
1.Med-surg: cardiovascular & respiratory
Answer: A · At least 15 hours a day
Why this is the answer
Long-term oxygen therapy improves survival in COPD with chronic hypoxaemia when used for at least 15 hours a day, including overnight. Patients must not smoke, because of the fire risk. Ambulatory oxygen for exercise is a separate assessment.
Answer
A · At least 15 hours a day
2.Med-surg: cardiovascular & respiratory
Answer: C · Acute respiratory distress syndrome
Why this is the answer
ARDS is acute, non-cardiogenic pulmonary oedema caused by widespread inflammation, triggered by sepsis, pneumonia, trauma or pancreatitis. It causes severe hypoxaemia that responds poorly to oxygen, with bilateral infiltrates not explained by heart failure. Treatment includes lung-protective ventilation and often prone positioning.
Answer
C · Acute respiratory distress syndrome
3.Med-surg: neuro, endocrine & renal
Answer: B · The feed can reduce phenytoin absorption, so the feed is often paused around the dose
Why this is the answer
Enteral feeds can bind phenytoin and greatly reduce how much is absorbed. Local protocols usually pause the feed before and after the dose and flush the tube. Drug levels are monitored.
Answer
B · The feed can reduce phenytoin absorption, so the feed is often paused around the dose
4.Med-surg: neuro, endocrine & renal
Answer: D · Call for emergency help: a haematoma may compress the airway
Why this is the answer
A rapidly enlarging neck haematoma with stridor is an airway emergency. Urgent help is called; in many units the clips or sutures are removed at the bedside to release the haematoma (following local emergency procedures) before definitive airway management and surgery.
Answer
D · Call for emergency help: a haematoma may compress the airway
5.Med-surg: GI, perioperative & oncology
Answer: D · With the head of the bed raised to reduce swelling
Why this is the answer
Raising the head reduces facial and airway swelling. The airway is monitored closely because swelling can increase over the first 24–48 hours.
Answer
D · With the head of the bed raised to reduce swelling
6.Med-surg: GI, perioperative & oncology
Answer: D · Line infection; escalate and take blood cultures
Why this is the answer
Fever and rigors after flushing a central line suggest a catheter-related bloodstream infection. The nurse escalates urgently, takes cultures from the line and peripherally per policy, and starts sepsis care.
Answer
D · Line infection; escalate and take blood cultures
7.Clinical nursing
Answer: A · Venturi mask
Why this is the answer
A Venturi mask entrains a set amount of room air, giving a fixed oxygen percentage regardless of the patient's breathing pattern. This makes it useful for patients at risk of hypercapnia.
A tachyarrhythmia with adverse features such as shock, myocardial ischaemia or reduced consciousness is unstable. Urgent senior help is needed, and synchronised cardioversion is often used.
Answer
B · Haemodynamic instability needing urgent treatment, possibly electrical cardioversion
9.Lab values & electrolytes
Answer: C · Aspirate from the sampling port with a sterile syringe
Why this is the answer
The catheter sampling port is cleaned and urine is aspirated with a sterile syringe, keeping the system closed. Urine in the drainage bag has been standing and can contain bacteria that multiplied there; opening the system raises the risk of infection.
Answer
C · Aspirate from the sampling port with a sterile syringe
10.Lab values & electrolytes
Answer: A · A very high creatine kinase (CK)
Why this is the answer
These signs suggest neuroleptic malignant syndrome, a medical emergency. Muscle rigidity releases CK, often to very high levels, and the white count is often raised. Myoglobin can damage the kidneys. The antipsychotic is stopped and supportive care is started.
Answer
A · A very high creatine kinase (CK)
11.Arterial blood gas interpretation
Answer: HCO₃⁻ = 27 mmol/L
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Change in PaCO₂
|70 − 40| = 30 mmHg → 3 × 10 mmHg
Expected HCO₃⁻
HCO₃⁻ = 24 + 1·3 = 27 mmol/L
Answer
HCO₃⁻ = 27 mmol/L
12.Arterial blood gas interpretation
Answer: PaCO₂ = 53.2 mmHg
Expected compensation: in metabolic acidosis Winter’s formula predicts PaCO₂ = 1.5·HCO₃⁻ + 8 ± 2 mmHg; a measured value above that range points to an additional respiratory acidosis, below it to an additional respiratory alkalosis. The anion gap AG = Na⁺ − (Cl⁻ + HCO₃⁻), normally about 8–12 mmol/L, separates high-gap from normal-gap metabolic acidosis; low albumin hides a high gap (add 2.5 per g/dL that albumin is below 4.0). The delta ratio (AG − 12)/(24 − HCO₃⁻) between about 0.8 and 2 fits a pure high-gap acidosis (some texts use 1 instead of 0.8), below that an added normal-gap acidosis, and above 2 an added metabolic alkalosis.
Expected PaCO₂
0.7·46 + 21 = 53.2 mmHg
Answer
PaCO₂ = 53.2 mmHg
The rise has a limit: PaCO₂ rarely goes above about 55 mmHg from compensation alone.
13.ECG rhythm strip interpretation
Answer: pause = 1.4 s
Narrow-complex tachycardia and pauses: supraventricular tachycardia (SVT) is a regular tachycardia at about 150–250/min with narrow QRS complexes; the P waves are usually not visible because they are hidden in the QRS complex or the T wave. Sinus tachycardia in an adult at rest is usually below about 150/min and has a visible P wave before every QRS; atrial flutter with 2:1 conduction often runs at about 150/min and shows sawtooth waves. In sinus arrest the sinus node stops firing for a moment: a pause with no P wave and no QRS whose length is not a whole number of P–P cycles (a pause of exactly two or three cycles points to sinus exit block instead).
Measure
35 small boxes from R to R across the pause
Convert
pause = 35 × 0.04 s = 1.4 s
Compare with P–P
1.40 ÷ 0.88 ≈ 1.6 P–P cycles, not a whole number
Answer
pause = 1.4 s
No P wave appears in the pause, and the pause is not a whole number of P–P cycles: sinus arrest. A pause of exactly two or three cycles would point to sinus exit block.
14.ECG rhythm strip interpretation
Answer: rate
Five steps for every strip: 1. rate (300 or 1500 method, or the 6-second method if irregular); 2. rhythm: are the R–R intervals equal; 3. P waves: present, upright in lead II, one before every QRS and all alike; 4. PR interval: 0.12–0.20 s and constant; 5. QRS duration: below 0.12 s. Only after the five steps name the rhythm. Normal sinus rhythm passes all five: 60–100/min, regular, upright P before every QRS, PR 0.12–0.20 s, QRS below 0.12 s.
Five steps
1. Rate: R–R = 32 small boxes, 1500 ÷ 32 ≈ 47 per minute.
2. Rhythm: regular, every R–R is 1.28 s.
3. P waves: upright, one before every QRS, all alike.
4. PR interval: 0.12 s, constant, within 0.12–0.20 s.
5. QRS: 0.10 s, narrow (below 0.12 s).
First abnormal step
rate → sinus bradycardia
Answer
rate
15.Prioritization & delegation
Answer: C · With the palms of the hands, not the fingertips
Why this is the answer
A wet plaster cast can be dented by fingertips, causing pressure points under the cast. It is handled with the palms, supported on pillows and left uncovered to dry.
Answer
C · With the palms of the hands, not the fingertips
16.Prioritization & delegation
Answer: A · Right shoulder pain from the gas used during surgery
Why this is the answer
Gas used to inflate the abdomen irritates the diaphragm and causes referred shoulder pain, which settles in a day or two. Jaundice, fever with worsening pain and signs of shock suggest complications.
Answer
A · Right shoulder pain from the gas used during surgery